What's it like in San Antonio?

Travellers to the San Antonio neighbourhood in Cali will be sure to enjoy their stay.

What's the best accommodation in San Antonio?

Based on our traveller data, Alko Hotel Casa Nispero is one of the top choices for your stay in San Antonio. This hotel offers free breakfast and a restaurant. Other good options for your stay in the area include Viajero Cali Hostel & Salsa School and San Antonio Hotel Boutique .

How many hotels will I be able to find in the San Antonio area?

If you're searching for places to stay in Cali, Expedia has something to meet your needs with 52 San Antonio hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in San Antonio, will I receive a refund?

Yes, most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to review the top deals on offer in San Antonio.

What can I see and do in this Cali neighbourhood?

Centro Cultural de Cali, Religious Art Museum and Enrique Buenaventura Municipal Theater are just a few of the places to visit in and around San Antonio. While you're out sightseeing, La Merced Archaeological Museum and Calima Gold Museum of the Bank of the Republic are a couple of additional sights to visit in Cali.

The Best Hotels in San Antonio, Cali - 2026 Updated Prices

An aerial view of a historic city center with terracotta-roofed buildings, a prominent red-brick structure, and modern high-rises in the background.

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Our top choices for San Antonio hotels

A lobby with a fountain, indoor plants, a dining area, and a painting of a house on the wall.

1. San Antonio Hotel Boutique

San Antonio

Jung

฿2,744 total

26 Sept - 27 Sept

An outdoor patio with a glass table and chairs, surrounded by lush greenery and illuminated by green lighting.

2. Alko Hotel Casa Nispero

San Antonio

Catherine

฿4,826 total

30 Sept - 1 Oct

An indoor dining area with tables and chairs, surrounded by hanging plants and greenery.

3. Viajero Cali Hostel & Salsa School

San Antonio

Jasmine

฿1,741 total

12 Oct - 13 Oct

A hallway with a large potted plant, a wooden bench, and a chandelier.

4. Casa feliz

San Antonio

฿489 total

2 Oct - 3 Oct

A modern kitchen with a central island, two wicker bar stools, a red pendant light, and a large window with a view.

5. Epifania Guest House

San Antonio

฿703 total

28 Sept - 29 Sept

A modern living room with a sofa, a coffee table, and decorative items.

6. Hotel habitat san antonio

San Antonio

฿1,599 total

9 Oct - 10 Oct

A courtyard with a wooden table and chairs, surrounded by potted plants and a climbing plant wall.

7. Hotel Casa Bresse

San Antonio

Stanislaw

฿1,619 total

27 Sept - 28 Sept

A stone fountain with a child statue, surrounded by potted plants and a tiled wall with a window and a framed picture.

8. casa hostal ave maria san antonio cali

San Antonio

Meyer

฿542 total

26 Sept - 27 Sept

A hotel lobby with a grand chandelier, seating area, and a decorative plant centerpiece.

9. Hotel Dann Carlton Cali

El Peñon, 0.4 km from San Antonio

Doris

฿3,993 total

26 Sept - 27 Sept

A restaurant with outdoor seating, a brick wall, and hanging lights.

10. Hotel el Peñón By Bithotels

El Peñon, 0.4 km from San Antonio

Avadawn

฿2,026 total

27 Sept - 28 Sept

A hotel with a modern facade, a prominent sign, and a landscaped entrance area.

11. InterContinental Cali by IHG

El Peñon, 0.3 km from San Antonio

Pedro

฿4,652 total

24 Oct - 25 Oct

A rooftop pool with a tiled edge, a sign indicating a Jacuzzi, and a view of a cityscape with buildings and hills in the background.

12. Faranda Collection Cali, a member of Radisson Individuals

La Merced, 0.6 km from San Antonio

Jose

฿3,784 total

3 Oct - 4 Oct

A modern hotel with a flat facade, balconies with plants, and a visible entrance.

13. Hotel Foresto 365

El Peñon, 0.5 km from San Antonio

Axel

฿2,016 total

26 Sept - 27 Sept

A rooftop pool area with lounge chairs, a hot tub, and tropical plants.

14. Veca Flats Centenario

Juanambú, 0.7 km from San Antonio

Danny Carlos

฿2,395 total

26 Sept - 27 Sept

A modern building with a sign for 'Passiflora Luxury Suites' at the entrance.

15. Passiflora luxury suite

1 km from San Antonio

Saul

฿1,603 total

27 Sept - 28 Sept

A historic building with a central courtyard, stone steps, and a traditional balcony.

16. Hotel Stein Colonial

Juanambú, 0.6 km from San Antonio

kevin

฿1,764 total

27 Sept - 28 Sept

A modern outdoor patio area with a staircase leading to an upper level, a seating area with chairs, and a bar counter.

17. Hampton by Hilton Cali, Colombia

1.1 km from San Antonio

Juan

฿2,555 total

2 Oct - 3 Oct

A modern indoor space with hanging wicker lamps, large windows, and indoor plants.

18. Now Hotel Cali - Adults Only

Juanambú, 1.1 km from San Antonio

Osvaldo

฿2,678 total

27 Sept - 28 Sept

19. Hotel Dann Cali

El Peñon, 0.4 km from San Antonio

Holmes

฿3,798 total

26 Sept - 27 Sept

A spacious lobby with a beige sofa, a chandelier, and a reception desk.

20. Hotel Obelisco

El Peñon, 0.7 km from San Antonio

Carlos

฿2,612 total

30 Sept - 1 Oct

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Compare popular hotels in San Antonio

Property	Property class	Guest rating
San Antonio Hotel Boutique	3.0 star property	9.2 Wonderful 69 reviews	View
Alko Hotel Casa Nispero	4.0 star property	9.4 Exceptional 246 reviews	View
Hotel Casa Bresse	2.5 star property	9.2 Wonderful 5 reviews	View
Viajero Cali Hostel & Salsa School	2.0 star property	9.0 Wonderful 68 reviews	View
casa hostal ave maria san antonio cali	2.0 star property	4.0 2 reviews	View

Where to stay in San Antonio

Find the best San Antonio areas for the activities you enjoy most.

A cityscape with dense urban buildings, a prominent hill, and a distant mountain range under a cloudy sky.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

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A yellow monument with a bell, surrounded by trees and a fence.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

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An aerial view of a city with dense high-rise buildings, a roundabout, and surrounding greenery.

El Peñon

While El Peñon may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Centenario Commercial Center and Gato de Tejada Monument.

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Las Vegas

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Pance

While Pance may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Chorrera del Indio and Los Arrayanes Recreational Center.

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Top San Antonio Hotel Reviews

Hilton Garden Inn Cali Ciudad Jardin

10/10 Excellent

"Overall the facilities are good. My room was silent and well equipped. Location convenient if you need to stay in the southern part of the city. Staff friendly and helpful. Two issues: scratches on the room floors and malfunction of the phone. Could never contact the front desk by phone."

Alko Hotel Casa Nispero

8/10 Good

"The hotel is as pictured although some of its amenities require a bit more upkeep. For example, our bathroom door was quirky and didn't always close. The entryway to the pool was tight and right in front of the hotel bar, and the pool shower was across from the restaurant tables. The cleaning staff is amazing and truly kind, but sadly we were not as keen with the reception staff. It seemed like there was a lot of mis/or lack there of communication between the staff and the management and general procedures were not answered within a timely manner."

San Antonio Hotel Boutique

10/10 Excellent

"I had an enjoyable albeit short (3 nights) stay at the San Antonio Hotel Boutique. Unfortunately, I left my phone in the taxi that dropped me off but Fonseco at the front desk was very helpful in trying to locate the driver. Although we were unable to contact him, I have since been in touch with someone who has the phone and am coordinating its return to the US. Both of the hotel proprietors, Ricardo and Nelson, were also extremely helpful and fluent English speakers. My room had a safe and was very comfortable and quiet, and came with breakfast each morning, with a selection that included eggs, ham, cheese, toast, coffee/chocolate/tea, juice and fruit. The San Antonio neighborhood was safe to walk around with excellent restaurants, art galleries, cafes and shops within walking distance - I visited and would recommend for dining La Boheme, Primos, and the Valle Pacific Ancestral Restaurante (shoutout to my server Dayana!). I was in Cali for a short side trip from Bogata in between dental clinic appointments and would have been more adventurous and explored more of the city but the short duration of my stay and not having a phone limited my choices. I also enjoyed the warmer weather compared to Bogota and definitely hope to go back some day for a longer visit!"

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Our top choices for San Antonio hotels

1. San Antonio Hotel Boutique

2. Alko Hotel Casa Nispero

3. Viajero Cali Hostel & Salsa School

4. Casa feliz

5. Epifania Guest House

6. Hotel habitat san antonio

7. Hotel Casa Bresse

8. casa hostal ave maria san antonio cali

9. Hotel Dann Carlton Cali

10. Hotel el Peñón By Bithotels

11. InterContinental Cali by IHG

12. Faranda Collection Cali, a member of Radisson Individuals

13. Hotel Foresto 365

14. Veca Flats Centenario

15. Passiflora luxury suite

16. Hotel Stein Colonial

17. Hampton by Hilton Cali, Colombia

18. Now Hotel Cali - Adults Only

19. Hotel Dann Cali

20. Hotel Obelisco

Compare popular hotels in San Antonio

Where to stay in San Antonio

Ciudad Jardín

Granada

El Peñon

Las Vegas

Pance

Top San Antonio Hotel Reviews

Hilton Garden Inn Cali Ciudad Jardin

Frequently asked questions