Find hotels in Puxico, MO from ฿1,993

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Puxico hotels

1. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (911 reviews)
"Hotel Staff was very friendly!"
United States
Alice
The price is ฿3,305
฿3,734 total
includes taxes & fees
28 Jun - 29 Jun
Fairfield Inn & Suites by Marriott Poplar Bluff

2. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (862 reviews)
"Nice quiet overnight stay."
United States
Tammy
The price is ฿3,059
฿3,425 total
includes taxes & fees
5 Jul - 6 Jul
Hampton Inn Poplar Bluff

3. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (1,006 reviews)
"Great place to stay. Clean, great staff and the food is good. Would stay again."
United States
Stephanie
The price is ฿3,594
฿4,059 total
includes taxes & fees
21 Jun - 22 Jun
Drury Inn & Suites Poplar Bluff

4. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very good, (1,000 reviews)
"Clean and parking was easy."
United States
Amy
The price is ฿2,450
฿2,744 total
includes taxes & fees
11 Jun - 12 Jun
Motel 6 Poplar Bluff, MO

5. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (746 reviews)
"Great staff especially Ms Wilma at the front desk!"
United States
Denise
The price is ฿3,174
฿3,586 total
includes taxes & fees
14 Jun - 15 Jun
Holiday Inn Poplar Bluff by IHG

6. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (95 reviews)
"This was such a quaint hotel in Marble Hill. The staff was friendly and attentive and the breakfast and little store are such a fun addition. We will be back!"
United States
Betsy
The price is ฿3,362
฿3,659 total
includes taxes & fees
8 Jun - 9 Jun
EC Reed's Mercantile and Hotel

7. Econo Lodge Dexter

Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (263 reviews)
"Room was ok, I was there for 4 nights and they never even emptied the trash"
United States
Robert
The price is ฿1,862
฿2,091 total
includes taxes & fees
16 Jun - 17 Jun
Econo Lodge Dexter

8. Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (409 reviews)
"Clean room, staff was super helpful"
United States
Katherine
The price is ฿2,837
฿3,186 total
includes taxes & fees
7 Jun - 8 Jun
Travelodge by Wyndham Dexter

9. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
2.5 star property
Poplar Bluff
7.8 out of 10, Good, (415 reviews)
"Room smelt very clean. Breakfast was good"
United States
Lori
The price is ฿3,060
฿3,456 total
includes taxes & fees
5 Jul - 6 Jul
Comfort Inn Poplar Bluff North

10. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
9.8 out of 10, Exceptional, (36 reviews)
"The property was clean and the staff was friendly. "
United States
Shelia
The price is ฿3,582
฿4,023 total
includes taxes & fees
14 Jun - 15 Jun
Hampton Inn By Hilton Dexter

11. OYO Hickory House Inn

OYO Hickory House Inn
2.5 star property
Dexter
5.6 out of 10, (138 reviews)
"We enjoyed every moment of our stay. Wonderful service—everyone was friendly and helpful."
United States
Albert
The price is ฿1,629
฿1,993 total
includes taxes & fees
18 Jun - 19 Jun
OYO Hickory House Inn

12. Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
Poplar Bluff
6.6 out of 10, (647 reviews)
"Easy to check in"
United States
Aisa
The price is ฿1,944
฿2,197 total
includes taxes & fees
30 Jun - 1 Jul
Super 8 by Wyndham Poplar Bluff Missouri

13. Dexter Inn

Dexter Inn
2.5 star property
Dexter
7.0 out of 10, Good, (348 reviews)
"Nice rooms, friendly staff, "
United States
Sarah
The price is ฿2,124
฿2,385 total
includes taxes & fees
22 Jun - 23 Jun
Dexter Inn

14. Lake Wappapello

Lake Wappapello
2.0 star property
Williamsville
10.0 out of 10, Exceptional, (2 reviews)
"Pet friendly. Family-friendly "
United States
Tonya
The price is ฿2,499
฿2,636 total
includes taxes & fees
7 Jun - 8 Jun
Lake Wappapello
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Puxico

Head to sights like Mark Twain National Forest and Mingo Wilderness as you discover Puxico.

Photo by Mike McClain
Open Photo by Mike McClain

Top Puxico Hotel Reviews

More cheap stays in Puxico

Frequently asked questions

What's the best place for a stay in Puxico?
Hampton Inn Poplar Bluff, located 18.8 mi (30.3 km) from the heart of Puxico, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Motel 6 Poplar Bluff, MO and Drury Inn & Suites Poplar Bluff. See all available top hotels, or vacation rentals in Puxico.
If I need to cancel my hotel reservation in Puxico, will I receive a refund?
Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.
What is staying in Puxico like?
Travellers to Puxico will find plenty to explore and enjoy. There are 56 hotels and other accommodation options in the surrounding area. Find out more about Puxico.
What is there to see in Puxico?
A couple of favourite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Take a look at what more there is to see and do in Expedia's Puxico guide.
What's the seasonal weather in Puxico?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Puxico is 1502 mm.

Explore a world of travel with Expedia