Prairie Home Holiday Rentals, Missouri: Private House Rentals

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Our top choices for Prairie Home hotels

A swimming pool area with a covered bench, a chair, and a sign indicating pool rules.

A modern room with a blue wall, a gray sofa, a wooden coffee table, and a yellow chair.

A hotel room with a desk, two chairs, a printer, a phone, a framed picture, and a 'No Smoking' sign.

A coffee station with two coffee machines and a variety of coffee pods and cups.

1. Holiday Inn Express Boonville by IHG

Boonville

Thomas

฿4,258

฿5,497 total

includes taxes & fees

8 Nov - 9 Nov

A casino with multiple gaming machines, an ATM, and a staircase leading to upper levels.

An outdoor patio with a fire feature, seating, and hanging flower baskets.

A restaurant interior with a unique hanging light fixture made of bottles, brick walls, and wooden furniture.

A spacious lobby with a patterned carpet, multiple seating areas including sofas and chairs, and a large chandelier.

2. Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

Boonville

Janeice

฿2,283

฿3,026 total

includes taxes & fees

9 Nov - 10 Nov

An indoor swimming pool with lounge chairs and a hot tub, surrounded by wooden walls and windows.

A hotel room with a desk, computer, and a sofa. There is a dining area in the background with chairs and tables.

A hotel room with a bed, a sofa, a coffee table, and framed pictures on the wall.

A hotel with an indoor pool, featuring a prominent sign and a brick facade.

3. Quality Inn & Suites Boonville - Columbia

Boonville

Derek

฿3,353

฿3,826 total

includes taxes & fees

9 Nov - 10 Nov

A hotel lobby with a reception desk, seating area, and a reception counter.

A gym with a treadmill, exercise bike, and weight machine.

A compact hotel room with a flat-screen TV, a microwave, a refrigerator, a bench, and a small table.

A hotel room with two beds, a nightstand, a lamp, and a patterned carpet.

4. Baymont by Wyndham Columbia, MO

Columbia

Susan

฿1,995

฿2,254 total

includes taxes & fees

18 Oct - 19 Oct

A patio area with a fire pit, outdoor seating, and a grill.

A modern dining area with a long wooden table, multiple chairs, a flat-screen TV mounted on a stone wall, and a fireplace.

A modern kitchen with built-in appliances, a wooden countertop, and a seating area with a chair.

A rooftop pool with lounge chairs and umbrellas, surrounded by a brick building with large windows.

5. TownePlace Suites by Marriott Columbia

Columbia

Barb

฿3,954

฿4,506 total

includes taxes & fees

1 Nov - 2 Nov

A modern office space with a meeting area featuring a large table and chairs, a purple accent wall, and a view through large windows.

A modern office space with a desk area, seating, and a hanging chair.

6. Tru By Hilton Columbia South

Columbia

Kevin M.

฿2,997

฿3,416 total

includes taxes & fees

1 Nov - 2 Nov

A covered outdoor seating area with wooden beams and a lantern, overlooking a brick building and greenery.

A modern interior with a seating area, wooden partitions, and large windows.

A formal dining table set with crystal glassware, plates, and napkins, with a decorative crystal centerpiece.

A modern gym with treadmills, weight machines, and free weights.

7. Courtyard by Marriott Columbia Missouri

Columbia

Jeremy

฿3,819

฿4,315 total

includes taxes & fees

18 Oct - 19 Oct

A modern lobby with a sectional sofa, a flat-screen TV, and a glass wall offering a view of the city.

An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and tables.

A hotel room with a large bed, a sofa, a desk, and a television.

A gym with treadmills, elliptical machines, and a bench.

8. Drury Inn & Suites Columbia Stadium Boulevard

Columbia

SHERILYN

฿3,353

฿3,788 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a dining area, a sofa, a TV, and a view of the city.

A banquet hall with round tables set for a formal event, featuring a patterned carpet and a high ceiling with chandeliers.

A hotel room with a large bed, two bedside tables with lamps, a desk with a computer, and a large window offering a view of the city.

A hotel lobby with a staircase, a bar area, and seating.

9. Wyndham Executive Center Columbia

Columbia

Shara

฿3,326

฿3,758 total

includes taxes & fees

30 Oct - 31 Oct

A hotel room with a bed, a sofa, a television, and a large window with curtains.

A kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave.

A motel with a covered parking area, multiple rooms, and a visible sign for a nearby Super 8 motel.

A hotel lobby with a reception desk, a framed welcome sign, and a large window with curtains.

10. Super 8 by Wyndham Boonville

Boonville

"Staff was very friendly and helpful. I was working nights on the highway and needed to find a place that would allow me to check in at 5:00am and after calling multiple hotels this was the only that would accommodate me. The room was clean and slightly updated. Only complaint was the bed frame was all metal and made a lot of noise when moving around on the bed. Overall I would stay here again."

John

฿2,394

฿2,732 total

includes taxes & fees

18 Oct - 19 Oct

A spacious living area with a blue sofa, leather armchairs, and a flat-screen TV mounted on a wooden cabinet. Large windows provide a view of parked cars outside.

A hotel lobby with a reception desk, a blue sofa, and a patterned rug.

A hotel room with a large flat-screen TV, two beds, a sofa, and a desk.

A restaurant with multiple tables and chairs, a counter with a coffee machine, and a menu board.

11. Comfort Suites Columbia - University Area

Columbia

Lisa

฿3,289

฿3,716 total

includes taxes & fees

1 Nov - 2 Nov

A modern interior with round tables and chairs, a bar area, and a large window offering a view of the outside.

A multi-story hotel with a covered entrance and a stone facade.

A patio area with outdoor seating, a pool, and a stone building facade.

A modern lounge area with a sofa, round tables, and chairs, a kitchen area, and large windows.

12. Best Western Plus Columbia Inn

Columbia

Shawn

฿2,742

฿3,098 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with clear signage indicating no lifeguard on duty and no diving.

A reception desk with a wooden finish and granite counter, a framed welcome sign, and a lamp.

A wedding reception table with a tiered white cake, floral decorations, and a menu stand.

A hotel room with a bed, a bathroom with a bathtub, a bedside table with a lamp, and a thermostat on the wall.

13. Hampton Inn & Suites Columbia at University

Columbia

Jamie

฿3,563

฿4,025 total

includes taxes & fees

18 Oct - 19 Oct

A modern living room with grey sofas, a coffee table, and a fireplace. There are framed pictures on the wall and a floor lamp.

A modern restaurant with blue cabinets, wooden tables and chairs, and a kitchen area with appliances.

A hotel room with a large bed, a desk with a lamp, a kitchenette, and a bathroom.

A reception desk with a wooden finish, three pendant lights, framed artwork on the wall, and a small display case with pastries.

14. Country Inn & Suites by Radisson, Columbia, MO

Columbia

Susan

฿2,822

฿3,188 total

includes taxes & fees

1 Nov - 2 Nov

A hotel entrance with a covered walkway, a brick facade, and a well-lit exterior.

A buffet with labeled containers of omelets and other food items.

A lobby with four armchairs, a coffee table, and a floor lamp. There are two wall-mounted light fixtures and a decorative wall piece.

A hotel room with two desks, each with a laptop and a chair, and a small cabinet.

15. Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Columbia

Jennifer

฿3,822

฿4,337 total

includes taxes & fees

1 Nov - 2 Nov

A lobby with a reception desk, two sofas, a coffee table, and a patterned rug.

An indoor swimming pool with clear water, surrounded by white walls and a tiled floor.

A hotel room with a large bed, a desk with a flat-screen TV, a chair, a desk lamp, and a nightstand with a lamp.

A modern restaurant with high tables and booths, large windows, and a patterned carpet.

16. Wingate by Wyndham - Columbia

Columbia

Carlos

฿2,887

฿3,262 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor seating area with tables and chairs, a bar, and a fire pit.

A sign for The Broadway hotel, a Doubletree by Hilton, with a water feature in front.

A multi-story hotel with a prominent entrance, a covered area, and a clear sky at dusk.

A modern restaurant with a bar area, red leather chairs, and a large mural on the wall.

17. The Broadway Columbia - a DoubleTree by Hilton

Columbia

Michelle

฿5,159

฿5,854 total

includes taxes & fees

1 Nov - 2 Nov

A spacious bar area with high tables and chairs, a large flat-screen TV mounted on the wall, and a bar stocked with bottles.

A modern bar area with a long counter, bar stools, and a fireplace.

An indoor swimming pool with a tiled floor, a glass barrier, and a lifeguard chair.

A hotel room with a sofa, a green ottoman, a desk with a lamp, and a framed cityscape picture on the wall.

18. Drury Plaza Hotel Columbia East

Columbia

Kevin

฿3,420

฿3,863 total

includes taxes & fees

18 Oct - 19 Oct

19. Hotel Frederick

Boonville

natalie

฿4,130

฿4,712 total

includes taxes & fees

21 Oct - 22 Oct

An indoor swimming pool with wooden beams, stone walls, and artificial trees.

A rustic interior with wooden tables and chairs, a fireplace, and a stone wall.

A spacious lobby with a wooden staircase and a second-floor balcony.

A log cabin-style room with a bed, a fireplace, a stone wall, a TV, and a large window.

20. Stoney Creek Hotel Columbia

Columbia

Brett

฿3,606

฿4,074 total

includes taxes & fees

18 Oct - 19 Oct

View all properties

Hotels recommended for families in Prairie Home

Baymont by Wyndham Columbia, MO

Columbia

฿1,995

฿2,254 total

includes taxes & fees

18 Oct - 19 Oct

Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

Boonville

฿2,283

฿3,026 total

includes taxes & fees

9 Nov - 10 Nov

Quality Inn & Suites Boonville - Columbia

Boonville

฿3,353

฿3,826 total

includes taxes & fees

9 Nov - 10 Nov

Tru By Hilton Columbia South

Columbia

฿2,997

฿3,416 total

includes taxes & fees

1 Nov - 2 Nov

Wyndham Executive Center Columbia

Columbia

฿3,326

฿3,758 total

includes taxes & fees

30 Oct - 31 Oct

Drury Inn & Suites Columbia Stadium Boulevard

Columbia

฿3,353

฿3,788 total

includes taxes & fees

18 Oct - 19 Oct

Holiday Inn Express Boonville by IHG

Boonville

฿4,258

฿5,497 total

includes taxes & fees

8 Nov - 9 Nov

Hotel Frederick

Boonville

฿4,130

฿4,712 total

includes taxes & fees

21 Oct - 22 Oct

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Top Prairie Home Hotel Reviews

Baymont by Wyndham Columbia, MO

10/10 Excellent

"No issues"

Hotel Blu

10/10 Excellent

"It was hard to find, due to us looking for hotel blu, and not a hotel 6 ( the sign had not changed. But overall it was clean, and quiet."

Wingate by Wyndham - Columbia

10/10 Excellent

"Very clean and helpful staff !"

Ramada by Wyndham Columbia

8/10 Good

"Worth the price - room was very clean and updated - the hotel itself is dated and the side door was a bit clunky to get into"

Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

10/10 Excellent

"Everything was excellent. Would definitely recommend"

Drury Plaza Hotel Columbia East

10/10 Excellent

"Great stay at Drury Hotels. Thought the food and drinks in the early evening was a nice touch. Breakfast was also good. Pet friendly. Would recommend."

Holiday Inn Columbia East by IHG

8/10 Good

"The hotel itself was nice but our bathroom appeared to have some old water damage that was not well repaired"

Red Roof Inn Columbia, MO

8/10 Good

"They were good listeners so not a good first impression but got better"

More cheap stays in Prairie Home

Hotel Blu

3402 Interstate 70 Dr SE Columbia MO

฿1,763

฿1,992 total

19 Oct - 20 Oct

includes taxes & fees

6.6/10 (246 reviews)

Baymont by Wyndham Columbia, MO

2500 I 70 Dr Sw Columbia MO

฿1,995

฿2,254 total

18 Oct - 19 Oct

includes taxes & fees

8.2/10 Very good! (1,068 reviews)

Ramada by Wyndham Columbia

901 Conley Rd Columbia MO

฿2,124

฿2,400 total

18 Oct - 19 Oct

includes taxes & fees

7.4/10 Good! (1,004 reviews)

Best Western Plus Columbia Inn

2904 Clark Lane Columbia MO

฿2,742

฿3,098 total

25 Oct - 26 Oct

includes taxes & fees

Country Inn & Suites by Radisson, Columbia, MO

817 N Keene St Columbia MO

฿2,822

฿3,188 total

1 Nov - 2 Nov

includes taxes & fees

Stoney Creek Hotel Columbia

2601 S Providence Rd Columbia MO

฿3,606

฿4,074 total

18 Oct - 19 Oct

includes taxes & fees

Frequently asked questions

What's the best place for a stay in Prairie Home?

Located 15.7 mi (25.3 km) from the heart of Prairie Home, Baymont by Wyndham Columbia, MO is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Drury Plaza Hotel Columbia East and Stoney Creek Hotel Columbia. See all available top hotels, or vacation rentals in Prairie Home.

If I need to cancel my hotel reservation in Prairie Home, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Prairie Home.

What's it like staying in Prairie Home?

Those travelling to Prairie Home will definitely enjoy the sights to see and things to do. There are 237 hotels and other accommodation options in the surrounding area. Find out more about Prairie Home.

What should I see while I'm in Prairie Home?

Places to visit in the wider area include Warm Springs Ranch, Isle of Capri Casino and Rock Bridge Memorial State Park. You'll also find Shelter Gardens and Columbia Mall in the area. Take a look at what more there is to see and do in Expedia's Prairie Home guide.

What's the seasonal weather like in Prairie Home?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 2°C. Average annual precipitation for Prairie Home is 1087 mm.

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Book Hotels in Prairie Home on Expedia.com

Find hotels in Prairie Home, MO from ฿1,992

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Prairie Home

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Prairie Home hotels

1. Holiday Inn Express Boonville by IHG

2. Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

3. Quality Inn & Suites Boonville - Columbia

4. Baymont by Wyndham Columbia, MO

5. TownePlace Suites by Marriott Columbia

6. Tru By Hilton Columbia South

7. Courtyard by Marriott Columbia Missouri

8. Drury Inn & Suites Columbia Stadium Boulevard

9. Wyndham Executive Center Columbia

10. Super 8 by Wyndham Boonville

11. Comfort Suites Columbia - University Area

12. Best Western Plus Columbia Inn

13. Hampton Inn & Suites Columbia at University

14. Country Inn & Suites by Radisson, Columbia, MO

15. Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

16. Wingate by Wyndham - Columbia

17. The Broadway Columbia - a DoubleTree by Hilton

18. Drury Plaza Hotel Columbia East

19. Hotel Frederick

20. Stoney Creek Hotel Columbia

Hotels recommended for families in Prairie Home

Baymont by Wyndham Columbia, MO

Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

Quality Inn & Suites Boonville - Columbia

Tru By Hilton Columbia South

Wyndham Executive Center Columbia

Drury Inn & Suites Columbia Stadium Boulevard

Holiday Inn Express Boonville by IHG

Hotel Frederick

Top Prairie Home Hotel Reviews

Baymont by Wyndham Columbia, MO

Hotel Blu

Wingate by Wyndham - Columbia

Ramada by Wyndham Columbia

Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

Drury Plaza Hotel Columbia East

Holiday Inn Columbia East by IHG

Red Roof Inn Columbia, MO

More cheap stays in Prairie Home

Hotel Blu

Baymont by Wyndham Columbia, MO

Ramada by Wyndham Columbia

Best Western Plus Columbia Inn

Country Inn & Suites by Radisson, Columbia, MO

Stoney Creek Hotel Columbia

Frequently asked questions

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