Find hotels in Prairie Home, MO from ฿1,464

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30 Dec - 31 Dec
Tomorrow
31 Dec - 1 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

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Our top choices for Prairie Home hotels

Exterior
Best Western Plus Columbia Inn

Best Western Plus Columbia Inn

Best Western Plus Columbia Inn
2.5 star property
Columbia
8.8 out of 10, Excellent, (1204)
"Stayed here several times and was very happy with our stay. "
United States
Reynaldo
The price is ฿2,160
฿2,440 total
includes taxes & fees
8 Jan - 9 Jan 2026
Best Western Plus Columbia Inn
Lobby
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1724)
"Was a nice hotel and staff was always around if needed"
United States
Kimberly
The price is ฿2,479
฿2,800 total
includes taxes & fees
20 Jan - 21 Jan 2026
Country Inn & Suites by Radisson, Columbia, MO
Lobby
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia
3.0 star property
Columbia
9.0 out of 10, Wonderful, (1212)
"Clean, friendly staff, comfortable bed and excellent shower ."
United States
dianne
The price is ฿2,519
฿2,846 total
includes taxes & fees
8 Jan - 9 Jan 2026
Wingate by Wyndham - Columbia
Studio Suite, 1 King Bed, Non Smoking | Desk, iron/ironing board, free cots/infant beds, free WiFi
Ramada by Wyndham Columbia

Ramada by Wyndham Columbia

Ramada by Wyndham Columbia
2.5 star property
Columbia
7.6 out of 10, Good, (1006)
"Decent room for the price point "
United States
William
The price is ฿2,057
฿2,324 total
includes taxes & fees
31 Dec - 1 Jan 2026
Ramada by Wyndham Columbia
Indoor pool, outdoor pool
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East
3.0 star property
Columbia
9.6 out of 10, Exceptional, (1349)
"We enjoyed our stay "
United States
Kathryn
The price is ฿3,101
฿3,504 total
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Plaza Hotel Columbia East
Exterior
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG
2.5 star property
Columbia
8.8 out of 10, Excellent, (1000)
"Very clean hotel with friendly staff"
United States
Sara
The price is ฿3,133
฿3,556 total
includes taxes & fees
18 Jan - 19 Jan 2026
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG
Exterior
Wyndham Executive Center Columbia

Wyndham Executive Center Columbia

Wyndham Executive Center Columbia
3.5 star property
Columbia
8.4 out of 10, Very good, (1006)
"Spotless room, friendly staff"
United States
Kent
The price is ฿2,678
฿3,025 total
includes taxes & fees
25 Jan - 26 Jan 2026
Wyndham Executive Center Columbia
Lobby sitting area
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO
2.5 star property
Columbia
8.2 out of 10, Very good, (636)
"Great stay highly recommend "
United States
Michael
The price is ฿1,820
฿2,056 total
includes taxes & fees
8 Jan - 9 Jan 2026
Baymont by Wyndham Columbia, MO
Lobby
Fairfield Inn & Suites by Marriott Columbia

Fairfield Inn & Suites by Marriott Columbia

Fairfield Inn & Suites by Marriott Columbia
2.5 star property
Columbia
8.2 out of 10, Very good, (580)
"The food was great and didn't taste like a breakfast buffet"
United States
Jennie
The price is ฿2,917
฿3,296 total
includes taxes & fees
5 Jan - 6 Jan 2026
Fairfield Inn & Suites by Marriott Columbia
Exterior
Holiday Inn Columbia East by IHG

Holiday Inn Columbia East by IHG

Holiday Inn Columbia East by IHG
3.0 star property
Columbia
8.4 out of 10, Very good, (1003)
"Buffet breakfast was a great option and the staff working it were awesome! "
United States
Matthew
The price is ฿3,545
฿4,040 total
includes taxes & fees
15 Jan - 16 Jan 2026
Holiday Inn Columbia East by IHG
Terrace/patio
Hampton Inn Columbia

Hampton Inn Columbia

Hampton Inn Columbia
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1001)
"Very professional, pleasant and welcoming staff at the hotel. Room neat and clean. Great choice for lodging."
United States
Gabrielle
The price is ฿2,258
฿2,551 total
includes taxes & fees
16 Jan - 17 Jan 2026
Hampton Inn Columbia
Desk, blackout curtains, soundproofing, iron/ironing board
Quality Inn & Suites Columbia I-70

Quality Inn & Suites Columbia I-70

Quality Inn & Suites Columbia I-70
2.5 star property
Columbia
7.0 out of 10, Good, (808)
"Clean rooms and excellent service"
United States
Sarah
The price is ฿1,681
฿1,899 total
includes taxes & fees
3 Jan - 4 Jan 2026
Quality Inn & Suites Columbia I-70
Indoor spa tub
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia
2.5 star property
Columbia
8.6 out of 10, Excellent, (1364)
"Great Stay"
United States
chasity
Stoney Creek Hotel Columbia
Desk, blackout curtains, free WiFi, bed sheets
Super 8 by Wyndham Columbia East

Super 8 by Wyndham Columbia East

Super 8 by Wyndham Columbia East
2.0 star property
Columbia
6.4 out of 10, (1000)
"Room was nice."
United States
Alia
The price is ฿1,681
฿1,899 total
includes taxes & fees
12 Jan - 13 Jan 2026
Super 8 by Wyndham Columbia East
Lobby
Drury Inn & Suites Columbia Stadium Boulevard

Drury Inn & Suites Columbia Stadium Boulevard

Drury Inn & Suites Columbia Stadium Boulevard
3.0 star property
Columbia
9.4 out of 10, Exceptional, (1003)
"Very clean and staff was excellent!"
United States
Audrey
The price is ฿2,848
฿3,218 total
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Inn & Suites Columbia Stadium Boulevard
Lobby
Hilton Garden Inn Columbia

Hilton Garden Inn Columbia

Hilton Garden Inn Columbia
3.0 star property
Columbia
8.6 out of 10, Excellent, (526)
"Staff was great!"
United States
Vince
The price is ฿3,388
฿3,844 total
includes taxes & fees
6 Jan - 7 Jan 2026
Hilton Garden Inn Columbia
Casino
Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
3.0 star property
Boonville
8.2 out of 10, Very good, (950)
"Very comfortable room and great location "
United States
Richard
The price is ฿2,394
฿3,111 total
includes taxes & fees
4 Jan - 5 Jan 2026
Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
Lobby
Tru By Hilton Columbia South

Tru By Hilton Columbia South

Tru By Hilton Columbia South
2.5 star property
Columbia
The price is ฿3,319
฿3,783 total
includes taxes & fees
2 Jan - 3 Jan 2026
Tru By Hilton Columbia South
BBQ/picnic Area
TownePlace Suites by Marriott Columbia

TownePlace Suites by Marriott Columbia

TownePlace Suites by Marriott Columbia
3.0 star property
Columbia
9.2 out of 10, Wonderful, (357)
"Great location! Clean"
United States
Tammie
The price is ฿3,454
฿3,937 total
includes taxes & fees
18 Jan - 19 Jan 2026
TownePlace Suites by Marriott Columbia
Property amenity
Courtyard by Marriott Columbia Missouri

Courtyard by Marriott Columbia Missouri

Courtyard by Marriott Columbia Missouri
3.0 star property
Columbia
8.6 out of 10, Excellent, (665)
"Great location. Very clean facility and pleasant staff. "
United States
Cathy
The price is ฿3,201
฿3,617 total
includes taxes & fees
25 Jan - 26 Jan 2026
Courtyard by Marriott Columbia Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Prairie Home Hotel Reviews

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

10/10 Excellent
"Yes, the room nice, comfortable and clean. The staffs were very nice with good costumer services. I surely recommend this property to a friend or family member."
Matenneh 2-night trip
Posted 8 days ago
Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

More cheap stays in Prairie Home

Days Inn by Wyndham Boonville

Days Inn by Wyndham Boonville

2401 Pioneer St Boonville MO
The price is ฿1,293 per night from 12 Jan to 13 Jan
฿1,293
฿1,464 total
12 Jan - 13 Jan 2026
includes taxes & fees
6/10 (1,006 reviews)

Frequently asked questions

What's the best place for a stay in Prairie Home?
Located 15.8 mi (25.4 km) from the heart of Prairie Home, Baymont by Wyndham Columbia, MO is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Stoney Creek Hotel Columbia and Wyndham Executive Center Columbia. See all available top hotels, or vacation rentals in Prairie Home.
If I need to cancel my hotel reservation in Prairie Home, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Prairie Home.
What's it like staying in Prairie Home?
Those travelling to Prairie Home will definitely enjoy the sights to see and things to do. There are 224 hotels and other accommodation options in the surrounding area. Find out more about Prairie Home.
What should I see while I'm in Prairie Home?
Places to visit in the wider area include Warm Springs Ranch, California Country Club and Isle of Capri Casino. You'll also find Rock Bridge Memorial State Park and Shelter Gardens in the area. Take a look at what more there is to see and do in Expedia's Prairie Home guide.
What's the seasonal weather like in Prairie Home?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 2°C. Average annual precipitation for Prairie Home is 1087 mm.