Search Hotels in Otay Mesa West, San Diego
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Otay Mesa West hotels
Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,728 reviews)
"Clean, quiet, helpful staff and simple airport transfers. "
Jill
The price is ฿5,535
฿6,362 total
includes taxes & fees
3 Apr - 4 Apr
Sycuan Casino Resort
Sycuan Casino Resort31.2 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,783 reviews)
"Very clean resort. "
Petrina
Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista9.2 km from Otay Mesa West
9.8 out of 10, Exceptional, (1,112 reviews)
"Great location "
Irma
The price is ฿6,827
฿7,523 total
includes taxes & fees
22 Mar - 23 Mar
Best Western Chula Vista/Otay Valley Hotel
Best Western Chula Vista/Otay Valley Hotel2.4 km from Otay Mesa West
7.8 out of 10, Good, (1,637 reviews)
"Clean rooms and the breakfast was amazing "
Vanessa
The price is ฿3,262
฿3,588 total
includes taxes & fees
15 Mar - 16 Mar
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel10.5 km from Otay Mesa West
9.2 out of 10, Wonderful, (3,747 reviews)
"My favorite place to stay"
Rubidia
The price is ฿4,273
฿4,709 total
includes taxes & fees
15 Mar - 16 Mar
Valli Hi Motel
Valli Hi Motel2.2 km from Otay Mesa West
8.4 out of 10, Very good, (1,000 reviews)
"Excelente "
Julio
SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake12.4 km from Otay Mesa West
9.6 out of 10, Exceptional, (592 reviews)
"Clean room and friendly staff "
Michael
The price is ฿5,405
฿5,956 total
includes taxes & fees
22 Mar - 23 Mar
Sheraton San Diego Resort
Sheraton San Diego Resort21.4 km from Otay Mesa West
8.4 out of 10, Very good, (3,370 reviews)
"Love this hotel will always stay here when I come to San Diego "
Darlene
The price is ฿3,993
฿5,995 total
includes taxes & fees
1 Apr - 2 Apr
San Diego Mission Bay Resort
San Diego Mission Bay ResortMission Bay, 26.8 km from Otay Mesa West
8.4 out of 10, Very good, (1,366 reviews)
"Great place for our family getaway! Loved the S’mores on the beach! "
Dani
The price is ฿7,634
฿10,464 total
includes taxes & fees
5 Apr - 6 Apr
Old Town Inn
Old Town Inn23.7 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,816 reviews)
"Clean, friendly staff, good value, nice pool area"
Mark
Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,070 reviews)
"great stay"
Jose
The price is ฿4,836
฿5,558 total
includes taxes & fees
22 Mar - 23 Mar
Lafayette Hotel & Club
Lafayette Hotel & Club21.3 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,515 reviews)
"Stunning hotel, I could have stayed there all day looking at every little design detail. "
Holly
The price is ฿7,314
฿8,393 total
includes taxes & fees
8 Apr - 9 Apr
Pleasant Inn
Pleasant Inn30.7 km from Otay Mesa West
8.4 out of 10, Very good, (1,333 reviews)
"Great stay!"
Gene
The price is ฿2,955
฿3,391 total
includes taxes & fees
15 Mar - 16 Mar
Best Western Americana Inn
Best Western Americana Inn2.1 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,228 reviews)
"Great stay"
Elisa
The price is ฿3,734
฿4,248 total
includes taxes & fees
18 Mar - 19 Mar
Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San Diego23.2 km from Otay Mesa West
8.4 out of 10, Very good, (1,001 reviews)
"Room was clean, pleasant staff and great breakfast "
Wendy
The price is ฿3,767
฿4,144 total
includes taxes & fees
15 Mar - 16 Mar
The Rambler Hotel
The Rambler Hotel8 km from Otay Mesa West
9.0 out of 10, Wonderful, (2,068 reviews)
"Absolutely amazing stay will def be coming back!"
Victor
The price is ฿3,761
฿4,352 total
includes taxes & fees
25 Mar - 26 Mar
Hampton Inn San Diego-Kearny Mesa
Hampton Inn San Diego-Kearny Mesa29.7 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,011 reviews)
"Absolutely wonderful hotel. Really great location with a lot of convenient dining and shopping options in the area. "
Maxwell
The price is ฿3,862
฿4,431 total
includes taxes & fees
5 Apr - 6 Apr
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld24.7 km from Otay Mesa West
7.4 out of 10, Good, (4,205 reviews)
"Good location friendly staff"
Anya
The price is ฿3,101
฿3,564 total
includes taxes & fees
22 Mar - 23 Mar
Humphreys Half Moon Inn
Humphreys Half Moon Inn22.3 km from Otay Mesa West
9.2 out of 10, Wonderful, (2,805 reviews)
"Great stay, highly recommend."
Ryan
The price is ฿5,657
฿7,135 total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town24.3 km from Otay Mesa West
9.2 out of 10, Wonderful, (718 reviews)
"Great place to stay, nice room Highly recommended !!"
Wilfredo
The price is ฿5,205
฿5,983 total
includes taxes & fees
24 Mar - 25 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa West
Find the best Otay Mesa West areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Ocean Beach
Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach and Dog Beach.
