Otay Mesa West Packages (Flight + Hotel)

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Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa West
US Grant Hotel

Downtown San Diego

4 out of top 10 points of interest in this area
4.5/5(138 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Find hotels in Downtown San Diego

Top hotels in Otay Mesa West

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is ฿6,342 per night from 5 Apr to 6 Apr
฿6,342
฿8,980 total
5 Apr - 6 Apr
includes taxes & fees
Paradise Point Resort & Spa
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
The price is ฿2,325 per night from 29 Mar to 30 Mar
฿2,325
฿2,673 total
29 Mar - 30 Mar
includes taxes & fees
7.8/10 Good! (3,278 reviews)
Need to update bedding.

Reviewed on 12 Mar 2026

Best Western Seven Seas
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is ฿12,188 per night from 25 Mar to 26 Mar
฿12,188
฿15,661 total
25 Mar - 26 Mar
includes taxes & fees
9/10 Wonderful! (3,406 reviews)
Hard Rock was very nice, clean and staff was nice. It is catered to mostly adults so I would probably not recommend to stay here with kids next time but a nice hotel nonetheless.

Reviewed on 11 Mar 2026

Hard Rock Hotel San Diego
See all 6,840 properties in Otay Mesa West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Otay Mesa West holiday package cost?
Discover the best of Otay Mesa West from as little as . Choose from a wonderful selection of flights, hotels and rental cars to suit every style and budget. You can score even better deals when you add some experiences or tours to your package.
How do I get a cheap travel package to Otay Mesa West?
Booking an Otay Mesa West holiday package with Expedia is the easiest way to save. We have over 550 partner airlines and 1,000,000 properties across the globe. With such an awesome range to select from, you'll have no trouble putting together your next dream holiday.
Where should I stay in Otay Mesa West?
You'll want to stay where the action is. Many people book hotels around popular attractions, like Las Americas Premium Outlets, North Island Credit Union Amphitheatre and Aquatica.
How far in advance should I book my Otay Mesa West holiday?
Smart travellers will likely want to book early. You can normally start comparing international fares on Expedia up to a year before your intended flight. If you're booking last minute, don't despair. Low prices sometimes appear just weeks before departure dates.
What does an Expedia Otay Mesa West travel package include?
It all depends on what type of getaway you're contemplating. Otay Mesa West holiday deals can include hotels, car rentals and flights. You can mix and match to find the travel package that fits your needs. You can also add on experiences and activities after you've booked to score even bigger discounts.
What should I know before booking an Otay Mesa West travel package?
Get ready to save with an Expedia travel package. Bundle your airfares, rental cars and hotels and pick up fabulous discounts. You're not limited to hotels, though. Book with us and select from beach villas, mountain cabins and everything in between!
Can I choose my airline with an Otay Mesa West Expedia holiday package?
With a holiday package, you're the boss. Whether you'd like to fly to Otay Mesa West in economy or business class, simply pick from the available airline options. Expedia has access to over 550 partner airlines all over the world.
If I'm not able to travel, can I cancel my Otay Mesa West holiday package?
You can. We get that even the best-laid plans can go awry, so we're here to help if you need to make changes to your Otay Mesa West holiday package. You may be able to cancel or change your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if you booked more than 24 hours ago. Head to our Customer Service Portal for further information. Also, be sure to check your itinerary for the nitty-gritty on change fees.

Popular places to visit

San Diego Zoo featuring zoo animals, landscape views and a pond

San Diego Zoo

See nature up-close and personal at one of the country’s largest and most educational zoos.

San Diego Zoo
USS Midway Museum which includes military items

USS Midway Museum

Experience the thrills and hardships of Navy life at this waterfront museum which has become a San Diego landmark.

USS Midway Museum
San Diego Aerial

Naval Base San Diego

Naval Base San Diego is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Experience the entertainment choices and acclaimed theatre scene in this walkable area.

Naval Base San Diego

Things to do

San Diego Premier Bottomless Mimosa Brunch Cruise

City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise

฿2,467
per adult
90% of travellers recommend
City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise
San Diego Zoo Safari Park

San Diego Zoo Safari Park

฿2,422
per adult
88% of travellers recommend
San Diego Zoo Safari Park
Oceanside Whale and Dolphin Watching Adventures

Oceanside Whale and Dolphin Watching Adventures

฿1,770
per adult
90% of travellers recommend
Oceanside Whale and Dolphin Watching Adventures
See all activities in San Diego
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.