Find hotels in O Brien, FL from ฿2,050

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4 Jan - 5 Jan
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5 Jan - 6 Jan
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9 Jan - 11 Jan
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16 Jan - 18 Jan

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Our top choices for O Brien hotels

Exterior
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1006)
"Great stay. Good breakfast. "
United States
Bob
The price is ฿3,688
฿4,149 total
includes taxes & fees
6 Jan - 7 Jan
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Breakfast area
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (478)
"Good overnight experience on a car trip. Nice staff."
United States
Luis
The price is ฿3,283
฿3,693 total
includes taxes & fees
1 Feb - 2 Feb
Hampton Inn & Suites Alachua I-75
Exterior
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
Lake City
8.8 out of 10, Excellent, (1039)
"Very clean property and a full hot breakfast buffet! "
United States
Julie
The price is ฿3,093
฿3,479 total
includes taxes & fees
1 Feb - 2 Feb
La Quinta Inn & Suite by Wyndham Lake City
Exterior
Tru by Hilton Lake City

Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1008)
"Cleanliness friendly service, very good free breakfast."
United States
Marsha
The price is ฿3,161
฿3,556 total
includes taxes & fees
25 Jan - 26 Jan
Tru by Hilton Lake City
Lobby
Best Western Plus Lake City

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1032)
"Great place to stay"
United States
Jack
The price is ฿3,025
฿3,403 total
includes taxes & fees
5 Jan - 6 Jan
Best Western Plus Lake City
Lobby
Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1005)
"Clean room, staff, everyone super helpful ."
United States
Devang
The price is ฿4,697
฿5,284 total
includes taxes & fees
5 Jan - 6 Jan
Hampton Inn & Suites Lake City
Lobby
Comfort Suites Lake City

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.6 out of 10, Exceptional, (1001)
"Great staff"
United States
Alison
The price is ฿3,376
฿3,798 total
includes taxes & fees
11 Jan - 12 Jan
Comfort Suites Lake City
Lobby
Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (176)
"Very clean, friendly staff, safe and quiet "
United States
Amy
The price is ฿3,373
฿3,795 total
includes taxes & fees
13 Jan - 14 Jan
Fairfield Inn & Suites Lake City
Exterior
Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1002)
"Great place"
United States
John
The price is ฿2,995
฿3,369 total
includes taxes & fees
11 Jan - 12 Jan
Holiday Inn & Suites Lake City by IHG
Exterior
Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.2 out of 10, Good, (670)
"It was clean, quiet, safe."
United States
donna
The price is ฿2,090
฿2,351 total
includes taxes & fees
7 Jan - 8 Jan
Super 8 by Wyndham Lake City
BBQ/picnic Area
Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.8 out of 10, Excellent, (1004)
"We had a good stay, the room was clean, check in quick and easy, the bed was comfortable."
United States
Alan
The price is ฿2,117
฿2,381 total
includes taxes & fees
5 Jan - 6 Jan
Americas Best Value Inn Lake City
Pillow-top beds, in-room safe, desk, blackout curtains
Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1005)
"Staff was great"
United States
Thomas
The price is ฿1,992
฿2,241 total
includes taxes & fees
5 Jan - 6 Jan
Days Inn by Wyndham Lake City I-75
Standard Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board
Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (622)
"Clean rooms, very friendly staff"
United States
Kristin L
The price is ฿2,144
฿2,358 total
includes taxes & fees
18 Jan - 19 Jan
Quality Inn White Springs Suwanee
Standard Cabin, 1 Queen Bed | Exterior
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (162)
"Fantastic place! Very nice amenities and service was wonderful"
United States
Annette
The price is ฿2,653
฿5,692 total
includes taxes & fees
13 Jan - 14 Jan
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Terrace/patio
Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (742)
"This is an excellent hotel while you roadtrip:)"
United States
Desiree Moreno
The price is ฿3,741
฿4,209 total
includes taxes & fees
11 Jan - 12 Jan
Home2 Suites by Hilton Lake City
Outdoor pool, pool loungers
Quality Inn Lake City

Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
7.8 out of 10, Good, (956)
"very clean room, great staff, we will be staying there again when we come to see our daughter "
United States
Gary
The price is ฿2,117
฿2,381 total
includes taxes & fees
3 Feb - 4 Feb
Quality Inn Lake City
1 bedroom, laptop workspace, free WiFi, bed sheets
Vista Verde Farm Retreat

Vista Verde Farm Retreat

Vista Verde Farm Retreat
2.0 star property
Lake City
9.6 out of 10, Exceptional, (13)
"This is my second time staying on this property and I love it "
United States
brandie
The price is ฿3,178
฿5,673 total
includes taxes & fees
5 Jan - 6 Jan
Vista Verde Farm Retreat
Iron/ironing board, free WiFi, bed sheets
Regal Inn

Regal Inn

Regal Inn
2.5 star property
Lake City
8.6 out of 10, Excellent, (547)
"Room was spotless"
United States
Judith
The price is ฿1,956
฿2,200 total
includes taxes & fees
6 Jan - 7 Jan
Regal Inn
Reception
BlueGem Motel

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (397)
"Great place to stay."
United States
Wesley
The price is ฿2,814
฿3,165 total
includes taxes & fees
8 Jan - 9 Jan
BlueGem Motel
Property amenity
Courtyard By Marriott Lake City

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (182)
"Nice place for a weekend trip to the springs close by.Would definitely stay here again."
United States
Mary
The price is ฿3,373
฿3,795 total
includes taxes & fees
11 Jan - 12 Jan
Courtyard By Marriott Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City

10/10 Excellent
"We did not eat at the hotel. "
Renee 1-night trip
Posted 4 days ago
Courtyard By Marriott Lake City

More cheap stays in O Brien

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

3340 W US Highway 90 Lake City FL
The price is ฿2,112 per night from 1 Feb to 2 Feb
฿2,112
฿2,376 total
1 Feb - 2 Feb
includes taxes & fees
8.2/10 Very Good! (90 reviews)

Frequently asked questions

Where is the best place to stay in O Brien?
La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Tru by Hilton Lake City. See all available top hotels, or vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
La Quinta Inn & Suite by Wyndham Lake City: Offers on-the-go, an indoor pool and free self parking. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Tru by Hilton Lake City are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Lafayette Blue Springs State Park in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

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