Find hotels in O Brien, FL from ฿1,385

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Our top choices for O Brien hotels

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (199 reviews)
"Perfect getaway for us with our dogs. It was peaceful and relaxing."
United States
Leila
The price is ฿3,513
฿6,683 total
includes taxes & fees
28 Apr - 29 Apr
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Vista Verde Farm Retreat

Vista Verde Farm Retreat
2.0 star property
Lake City
9.8 out of 10, Exceptional, (17 reviews)
"Beautiful spot with friendly horses :) "
United States
Dagmara
The price is ฿3,633
฿6,310 total
includes taxes & fees
14 Apr - 15 Apr
Vista Verde Farm Retreat

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (706 reviews)
"Breakfast included cooked-to order scrambled eggs & sausage."
United States
Patricia
The price is ฿2,015
฿2,267 total
includes taxes & fees
10 May - 11 May
Super 8 by Wyndham Lake City

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (658 reviews)
"Great breakfast! The best staff you can get at a hotel!"
United States
vicki
The price is ฿2,178
฿2,396 total
includes taxes & fees
27 Apr - 28 Apr
Quality Inn White Springs Suwanee

Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.0 out of 10, Good, (1,003 reviews)
"Low cost but worth it"
United States
Michael
The price is ฿2,070
฿2,328 total
includes taxes & fees
14 Apr - 15 Apr
Days Inn by Wyndham Lake City I-10

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
8.0 out of 10, Very good, (140 reviews)
"Dog friendly and price."
United States
John
The price is ฿2,050
฿2,307 total
includes taxes & fees
14 Apr - 15 Apr
Motel 6 – Lake City, Fl – Medical Center

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (603 reviews)
"room was clean and the air conditioning worked great would recommend"
United States
david
The price is ฿2,081
฿2,341 total
includes taxes & fees
14 Apr - 15 Apr
Palms Garden Inn

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (232 reviews)
"Very nice hotel!"
United States
Travis
The price is ฿3,575
฿4,022 total
includes taxes & fees
26 Apr - 27 Apr
Courtyard By Marriott Lake City

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (499 reviews)
"Breakfast awesome Parking great Staff awesome "
United States
Bryan
The price is ฿3,111
฿3,500 total
includes taxes & fees
10 May - 11 May
Hampton Inn & Suites Alachua I-75

The Blanche

The Blanche
2.0 star property
Lake City
9.2 out of 10, Wonderful, (181 reviews)
"Loved the hotel and the location! The bed was very very soft and the microfiber sheets were thin and hot!"
United States
Kim
The price is ฿4,758
฿5,352 total
includes taxes & fees
14 Apr - 15 Apr
The Blanche

Regal Inn

Regal Inn
2.5 star property
Lake City
8.6 out of 10, Excellent, (578 reviews)
"Nice staff, the room was clean and the bed was comfortable. "
United States
Karen
The price is ฿1,988
฿2,236 total
includes taxes & fees
15 Apr - 16 Apr
Regal Inn

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,041 reviews)
"Clean room, easy check in/out, friendly staff, friendly staff, simple but delicious breakfast. "
United States
Sara
The price is ฿3,317
฿3,732 total
includes taxes & fees
15 Apr - 16 Apr
Best Western Plus Lake City

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.6 out of 10, Excellent, (28 reviews)
"We had a good family getaway and was impressed how the camping experience was . Me and my family had an awesome outdoor experience and we will return again . The people their welcomed you like family and mad the trip and safe "
United States
amy
The price is ฿865
฿1,385 total
includes taxes & fees
14 Apr - 15 Apr
Suwannee River Rendezvous

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,006 reviews)
"Clean place to stay "
United States
Michelle
The price is ฿2,151
฿2,420 total
includes taxes & fees
15 Apr - 16 Apr
Americas Best Value Inn Lake City

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,003 reviews)
"Quiet comfortable and courteous staff. We Had great time!"
United States
Samantha
The price is ฿2,025
฿2,278 total
includes taxes & fees
14 Apr - 15 Apr
Days Inn by Wyndham Lake City I-75

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,004 reviews)
"Great stay, nice area"
United States
Jennifer
The price is ฿3,332
฿3,748 total
includes taxes & fees
19 Apr - 20 Apr
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (224 reviews)
"Great place..great breakfast"
United States
Michelle
The price is ฿3,812
฿4,289 total
includes taxes & fees
21 Apr - 22 Apr
Fairfield Inn & Suites Lake City

Gateway Inn

Gateway Inn
2.5 star property
Lake City
7.8 out of 10, Good, (180 reviews)
"The staff were so nice and welcoming. More than enough space in the rooms!!"
United States
Alyanise
The price is ฿1,666
฿1,874 total
includes taxes & fees
23 Apr - 24 Apr
Gateway Inn

Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.0 out of 10, Very good, (1,008 reviews)
"Great hotel and staff"
United States
Cynthia
The price is ฿2,404
฿2,705 total
includes taxes & fees
10 May - 11 May
Quality Inn Lake City

High Springs Country Inn

High Springs Country Inn
2.0 star property
High Springs
8.4 out of 10, Very good, (26 reviews)
"Friendly and helpful staff, clean room and plenty of parking "
United States
Joseph
The price is ฿2,509
฿2,822 total
includes taxes & fees
16 Apr - 17 Apr
High Springs Country Inn
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

More cheap stays in O Brien

Frequently asked questions

Where is the best place to stay in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are La Quinta Inn & Suite by Wyndham Lake City and Best Western Plus Lake City. See all available top hotels, or vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Provides buffet, an outdoor pool and complimentary high-speed (wired) Internet access. La Quinta Inn & Suite by Wyndham Lake City and Best Western Plus Lake City are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Bob's River Place and Lake City Mall in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

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