Default HTG hotel image

Search Hotels in North Clayton, St. Louis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for North Clayton hotels

A modern lounge area with a stone fireplace, comfortable seating, and a bar in the background.

1. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
North Clayton
8.8 out of 10, Excellent, (1,002 reviews)
"Great location - staff was awesome!"
United States
Kevin
The price is ฿4,532
฿5,335 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

2. SpringHill Suites St. Louis Brentwood

SpringHill Suites St. Louis Brentwood
3.0 star property
3.6 km from North Clayton
9.0 out of 10, Wonderful, (1,002 reviews)
"Staff was very friendly and rooms were clean."
United States
Aaron
The price is ฿4,195
฿4,949 total
includes taxes & fees
1 Nov - 2 Nov
SpringHill Suites St. Louis Brentwood
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

3. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
3.1 km from North Clayton
9.6 out of 10, Exceptional, (1,001 reviews)
"Excellent place to stay. Beautiful hotel, amazing friendly and attentive staff. Would highly recommend!!"
United States
Janell
The price is ฿4,392
฿5,216 total
includes taxes & fees
1 Nov - 2 Nov
Drury Plaza Hotel St. Louis Brentwood
An outdoor patio with a fire pit, seating, and a building in the background.

4. Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
3 km from North Clayton
9.4 out of 10, Exceptional, (908 reviews)
"Everything is great here. Stay here every time I’m in St. Louis, they are accommodating, nice and it’s very clean. I highly recommend it."
United States
Wendy
The price is ฿3,962
฿4,832 total
includes taxes & fees
18 Oct - 19 Oct
Courtyard by Marriott St. Louis Brentwood
The Clayton Plaza Hotel sign with a stone wall and plants in front.

5. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
0.8 km from North Clayton
9.0 out of 10, Wonderful, (3,472 reviews)
"Great location, lots of things to do in the area and the staff was amazing!"
United States
Daniele
The price is ฿3,072
฿3,586 total
includes taxes & fees
25 Oct - 26 Oct
Clayton Plaza Hotel & Extended Stay
A courtyard with outdoor seating, a central fountain, and a view of a tower.

6. The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
2.7 km from North Clayton
9.4 out of 10, Exceptional, (701 reviews)
"Beautiful hotel and very clean. We had a wonderful stay!"
United States
Rosalyn
The price is ฿5,105
฿5,870 total
includes taxes & fees
1 Nov - 2 Nov
The Knight Center at Washington University
A rooftop restaurant with round tables, chairs, and a view of the city.

7. Moonrise Hotel

Moonrise Hotel
4.0 star property
3.7 km from North Clayton
9.0 out of 10, Wonderful, (2,038 reviews)
"Great location"
United States
Katherine
The price is ฿5,405
฿6,427 total
includes taxes & fees
3 Nov - 4 Nov
Moonrise Hotel
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

8. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
9 km from North Clayton
9.2 out of 10, Wonderful, (1,003 reviews)
"This is a great place to stay at !"
United States
Daisy
The price is ฿3,688
฿4,573 total
includes taxes & fees
18 Oct - 19 Oct
Hyatt Select St. Louis Airport
An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

9. Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport
2.5 star property
9.2 km from North Clayton
9.0 out of 10, Wonderful, (237 reviews)
"Friendly staff, convenient location, quiet room, comfortable bed."
United States
Leia
The price is ฿4,319
฿5,197 total
includes taxes & fees
29 Oct - 30 Oct
Hampton Inn By Hilton St Louis Airport
A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

10. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
3.0 star property
9.7 km from North Clayton
9.2 out of 10, Wonderful, (1,708 reviews)
"Staff was wonderful..great location with BBQ restaurant next door"
United States
Mary
The price is ฿3,246
฿3,854 total
includes taxes & fees
18 Oct - 19 Oct
Wingate by Wyndham St. Louis Airport
An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

11. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 5.9 km from North Clayton
9.4 out of 10, Exceptional, (1,004 reviews)
"It was clean, free parking available and great location for our purpose"
United States
Debbie
The price is ฿4,647
฿5,480 total
includes taxes & fees
9 Nov - 10 Nov
Hampton Inn & Suites St. Louis at Forest Park
A cozy lounge area with leather sofas, a fireplace, and a bar counter.

12. The Cheshire

The Cheshire
4.0 star property
3.8 km from North Clayton
8.8 out of 10, Excellent, (1,003 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is ฿4,976
฿5,909 total
includes taxes & fees
18 Oct - 19 Oct
The Cheshire
A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

13. Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
9.4 km from North Clayton
9.2 out of 10, Wonderful, (1,436 reviews)
"Excellent place to stay, highly recommend."
United States
Ethan
The price is ฿3,856
฿4,563 total
includes taxes & fees
18 Oct - 19 Oct
Drury Inn & Suites St. Louis Airport
An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

14. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 7.5 km from North Clayton
8.6 out of 10, Excellent, (1,006 reviews)
"Staff was nice and helpful food was great and room was amazing!!! "
United States
paullita jeanne
The price is ฿5,213
฿6,096 total
includes taxes & fees
18 Oct - 19 Oct
Home2 Suites by Hilton St. Louis/Forest Park
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

15. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
9.7 km from North Clayton
9.2 out of 10, Wonderful, (3,290 reviews)
"Excellent stay"
United States
Murphy
The price is ฿3,017
฿3,583 total
includes taxes & fees
18 Oct - 19 Oct
Pear Tree Inn St. Louis Airport
A buffet with fruits, pastries, and beverages.

16. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
8.6 km from North Clayton
8.4 out of 10, Very good, (1,169 reviews)
"Great stay"
United States
Anthony
The price is ฿3,962
฿4,635 total
includes taxes & fees
29 Oct - 30 Oct
Renaissance St. Louis Airport Hotel
A courtyard with outdoor seating, a fire pit, and a well-maintained garden.

17. Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur
3.0 star property
Creve Coeur, 9 km from North Clayton
8.6 out of 10, Excellent, (1,002 reviews)
"Nice clean property Friendly helpful staff"
United States
Scott
The price is ฿3,806
฿4,424 total
includes taxes & fees
18 Oct - 19 Oct
Courtyard by Marriott St Louis Creve Coeur
A bar area with a long counter displaying numerous bottles of alcohol and several empty wine glasses lined up.

18. Holiday Inn St Louis SW - Route 66 by IHG

Holiday Inn St Louis SW - Route 66 by IHG
3.0 star property
12.4 km from North Clayton
9.2 out of 10, Wonderful, (589 reviews)
"I like the hotel completely. The cleanliness and staff and restaurant were amazing"
United States
Eric
The price is ฿3,957
฿4,706 total
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn St Louis SW - Route 66 by IHG
A modern lobby with a fireplace, comfortable seating, and a large TV screen.

19. Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport
2.5 star property
11.2 km from North Clayton
8.0 out of 10, Very good, (1,103 reviews)
"Property was very clean, and the free breakfast was honestly above and beyond the typical free hotel breakfasts we’ve had."
United States
Ethan
The price is ฿2,822
฿3,301 total
includes taxes & fees
25 Oct - 26 Oct
Best Western Plus St. Louis West-Westport
A swimming pool with a metal ladder, surrounded by chairs and large windows offering a view of the sunset.

20. La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66
3.0 star property
12.3 km from North Clayton
8.4 out of 10, Very good, (1,008 reviews)
"Great place!"
United States
Edward
The price is ฿3,363
฿3,909 total
includes taxes & fees
1 Nov - 2 Nov
La Quinta Inn & Suites by Wyndham St Louis Route 66
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in North Clayton

Find the best North Clayton areas for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top North Clayton Hotel Reviews

Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

10/10 Excellent
"Super friendly and helpful staff! Room was clean and comfortable. The breakfast was nothing special, but they could have used a little more help as there seemed to be one overworked staff member in charge of breakfast. This is a unique and historic building, which adds to the charm of this hotel. All-in-all, a nice place to stay."
Lorna 1-night trip
Posted 13 hours ago
Home2 Suites by Hilton St. Louis Downtown

Frequently asked questions

What is North Clayton like?
Travellers to St. Louis's North Clayton neighbourhood will be sure to enjoy a stay here.
What's a favourite place to stay in North Clayton?
Based on our traveller data, Hampton Inn & Suites Clayton/St. Louis-Galleria Area is one of the top choices for your stay in North Clayton. This hotel offers free breakfast and an indoor pool.
How many hotels will I find in the North Clayton area?
If you're searching for places to stay in St. Louis, choose from one of Expedia's 11 hotels and other accommodation options in North Clayton.
If I need to cancel my hotel reservation in North Clayton, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best deals available in North Clayton.
What is there to do in this St. Louis neighbourhood?
St. Louis Zoo, Shaw Park Tennis Center and Saint Louis Galleria Mall are just a few of the places to visit in and around North Clayton. While you're out sightseeing, Heman Park Tennis Center and Tao Tennis Center are a couple of additional sights to visit in St. Louis.