Find hotels in North Central Florida, FL from ฿1,645

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for North Central Florida hotels

Lobby
Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
8.2 out of 10, Very good, (83)
"Large room, comfortable bed, clean, pet friendly"
United States
D'Ann
The price is ฿1,902
฿2,139 total
includes taxes & fees
28 Dec - 29 Dec
Motel 6 – Lake City, Fl – Medical Center
Free daily buffet breakfast
Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very good, (775)
"Have stayed here whenever we are in town. Always god stay."
United States
Gregg
The price is ฿3,747
฿4,122 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Live Oak by IHG
Double Room, Non Smoking | Laptop workspace, free WiFi
High Springs Country Inn

High Springs Country Inn

High Springs Country Inn
2.0 star property
High Springs
8.2 out of 10, Very good, (17)
"Great remodel of a retro motel."
United States
Kathleen
The price is ฿2,433
฿2,737 total
includes taxes & fees
6 Jan - 7 Jan 2026
High Springs Country Inn
Outdoor pool, pool loungers
Quality Inn & Suites Palatka Riverfront

Quality Inn & Suites Palatka Riverfront

Quality Inn & Suites Palatka Riverfront
2.5 star property
Palatka
8.2 out of 10, Very good, (1000)
"We like the location on the river. Nice grounds. Friendly staff."
United States
Judy
The price is ฿2,833
฿3,144 total
includes taxes & fees
11 Jan - 12 Jan 2026
Quality Inn & Suites Palatka Riverfront
Sports facility
Hampton Inn Palatka

Hampton Inn Palatka

Hampton Inn Palatka
2.5 star property
Palatka
9.2 out of 10, Wonderful, (633)
"The front desk person at check in was very nice and made check in easy. "
United States
Kathleen
The price is ฿3,619
฿4,017 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hampton Inn Palatka
Property amenity
Staybridge Suites Gainesville I-75 by IHG

Staybridge Suites Gainesville I-75 by IHG

Staybridge Suites Gainesville I-75 by IHG
3.0 star property
Gainesville
9.4 out of 10, Exceptional, (910)
"Great hotel with clean rooms and friendly staff!"
United States
Denise
The price is ฿4,319
฿4,859 total
includes taxes & fees
1 Jan - 2 Jan 2026
Staybridge Suites Gainesville I-75 by IHG
Restaurant
The Gator Den Motel

The Gator Den Motel

The Gator Den Motel
2.5 star property
Dunnellon
9.2 out of 10, Wonderful, (487)
"Friendly staff, spacious room, restaurant on premise with good food and cocktails."
United States
Brenda
The price is ฿3,416
฿3,809 total
includes taxes & fees
28 Dec - 29 Dec
The Gator Den Motel
Lobby
Gator Town Inn

Gator Town Inn

Gator Town Inn
2.0 star property
Gainesville
7.6 out of 10, Good, (819)
"A good reasonable hotel for the stay."
United States
Damian
The price is ฿1,989
฿2,237 total
includes taxes & fees
28 Dec - 29 Dec
Gator Town Inn
Basic Room, Non Smoking | Free WiFi, bed sheets
University Inn Gainesville

University Inn Gainesville

University Inn Gainesville
2.0 star property
Gainesville
6.0 out of 10, (69)
"I love staying at the university inn hotel I always have a wonderful stay "
United States
Antonio
The price is ฿1,818
฿2,045 total
includes taxes & fees
28 Dec - 29 Dec
University Inn Gainesville
Lobby
Hampton Inn Gainesville

Hampton Inn Gainesville

Hampton Inn Gainesville
2.5 star property
Gainesville
8.8 out of 10, Excellent, (988)
"Room was super clean, the staff was very nice. The breakfast was very good! "
United States
Chad
The price is ฿2,268
฿2,552 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hampton Inn Gainesville
Exterior
Best Western Starke

Best Western Starke

Best Western Starke
2.5 star property
Starke
8.6 out of 10, Excellent, (665)
"staff was great but construction was noisy."
United States
Duane
The price is ฿2,455
฿2,725 total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Starke
Free buffet breakfast on weekdays
Holiday Inn Express Palatka Northwest by IHG

Holiday Inn Express Palatka Northwest by IHG

Holiday Inn Express Palatka Northwest by IHG
2.5 star property
Palatka
9.2 out of 10, Wonderful, (565)
"Great hotel "
United States
IVORY
The price is ฿3,946
฿4,380 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express Palatka Northwest by IHG
Lobby
SpringHill Suites by Marriott Gainesville

SpringHill Suites by Marriott Gainesville

SpringHill Suites by Marriott Gainesville
3.0 star property
Gainesville
8.8 out of 10, Excellent, (1005)
"Staff was great room was clean breakfast was amazing"
United States
Carol
The price is ฿2,610
฿2,936 total
includes taxes & fees
1 Jan - 2 Jan 2026
SpringHill Suites by Marriott Gainesville
Lobby
Quality Inn Gainesville I-75

Quality Inn Gainesville I-75

Quality Inn Gainesville I-75
2.5 star property
Gainesville
7.6 out of 10, Good, (909)
"Room was nice and cleaned and front desk was very helpful "
United States
Jitendra
The price is ฿2,237
฿2,517 total
includes taxes & fees
1 Jan - 2 Jan 2026
Quality Inn Gainesville I-75
Exterior
La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
3.0 star property
Gainesville
9.0 out of 10, Wonderful, (1130)
"Excellent food and lots of choices"
United States
Marianne
The price is ฿3,077
฿3,461 total
includes taxes & fees
27 Dec - 28 Dec
La Quinta by Wyndham Gainesville
Deluxe Room, 2 Queen Beds, Non Smoking | Premium bedding, desk, blackout curtains, free WiFi
HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western
2.5 star property
Gainesville
8.4 out of 10, Very good, (1802)
"Awesome place to stay."
United States
Aristeo
The price is ฿2,363
฿2,658 total
includes taxes & fees
26 Jan - 27 Jan 2026
HOM Hotel Gainesville, SureStay Collection by Best Western
Restaurant
Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1330)
"Great location right off of I 75.. quick stay for a long trip . "
United States
Mariel
The price is ฿3,293
฿3,705 total
includes taxes & fees
1 Jan - 2 Jan 2026
Drury Inn & Suites Gainesville
Lobby
Comfort Suites Gainesville near University

Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
2.5 star property
Gainesville
9.2 out of 10, Wonderful, (1158)
"Great staff, clean room"
United States
Akbar
The price is ฿2,610
฿2,936 total
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites Gainesville near University
Exterior
Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville
3.5 star property
Gainesville
8.4 out of 10, Very good, (1001)
"I will recommend my friends and family to come at this location anytime they are in gainesville "
United States
Recardo
The price is ฿3,009
฿3,386 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hilton University of Florida Conference Center Gainesville
Exterior
Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
3.0 star property
Downtown Gainesville
9.2 out of 10, Wonderful, (1101)
"Great location great staff great experience I have stayed at the hotel before multiple times an again."
United States
Charles
The price is ฿2,773
฿3,120 total
includes taxes & fees
28 Dec - 29 Dec
Hyatt Place Gainesville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Great weekend hotel deals in North Central Florida, FL

Showing deals for:2 Jan - 4 Jan

Image gallery for Quality Inn & Suites Ocala I-75

Room, 1 King Bed, Accessible, Non Smoking | Premium bedding, individually decorated, desk, blackout curtains

Quality Inn & Suites Ocala I-75

2.5 star property
Ocala
8.2/10Very good (302 reviews)
20% off
Price is ฿2,710
฿6,042 total
includes taxes & fees
Quality Inn & Suites Ocala I-75
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular North Central Florida attractions

A distant view of The University of Florida in the morning

University of Florida

4.6/5 (1,701 reviews)
Take a campus tour or just explore the area of University of Florida during your trip to Gainesville. Stroll along the lakeside or attend a sporting event in the area.
See properties
At the Gators home opener with 90,000 of my closest friends. A football game at Florida Field is an incredible experience. Energy not to be missed. This is probably one of the greatest stadiums in college football.
Photo by D Lawrence
Open Photo by D Lawrence

Ben Hill Griffin Stadium

4.5/5 (585 reviews)
Catch an event at Ben Hill Griffin Stadium during your trip to Gainesville. Stroll along the lakeside or attend a sporting event in the area.
See properties

Learn more about North Central Florida

Festivals, a university vibe and sights from Devil's Milhopper Geological State Park to San Felasco Hammock Preserve State Park—discover it all in North Central Florida.

See all hotels in North Central Florida
One of the famous glass bottom boats in Silver Springs State Park (Ocala, FL) floats by on the crystal clear water of the Silver River. If you visit Silver Springs, you must take one of these boat rides. In addition to seeing the underwater springs, we also saw manatees, alligators, turtles, monkeys, and birds on our 90 minute tour. #silversprings #florida
Photo by Jen - Nealys On Wheels
Open Photo by Jen - Nealys On Wheels

Top North Central Florida Hotel Reviews

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"The cabins were extremely clean. Great place to getaway… can’t wait to go back! Such a cute setup… Great location for exploring state parks. No complaints personally… perfect getaway whether alone or with someone A++++"
gilberto 1-night trip
Posted 2 days ago
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

More cheap stays in North Central Florida

Motel 6 Ocala, FL - Conference Center

Motel 6 Ocala, FL - Conference Center

3810 NW Blitchton Road Ocala FL
The price is ฿1,476 per night from 14 Jan to 15 Jan
฿1,476
฿1,645 total
14 Jan - 15 Jan 2026
includes taxes & fees
6/10 (713 reviews)