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Check prices for these dates

This weekend
28 Aug - 30 Aug
Next weekend
4 Sep - 6 Sep

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Our top choices for Murex Lakes hotels

A beach with a view of the ocean and a sunset.

1. Island Inn

Island Inn
3.5 star property
West End, 0.8 km from Murex Lakes
9.4 out of 10, Exceptional, (1,150 reviews)
"Wonderful room and stay. Beachfront!"
United States
Cindi
The price is ฿6,527
฿7,277 total
includes taxes & fees
31 Aug - 1 Sept
Island Inn
A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.

2. Casa Ybel Resort

Casa Ybel Resort
2.5 star property
Ybel, 3 km from Murex Lakes
8.8 out of 10, Excellent, (415 reviews)
"The entire stay was so enjoyable. Staff was friendly and very responsive. Beautiful complex and well maintained"
United States
John
The price is ฿10,007
฿11,157 total
includes taxes & fees
13 Sept - 14 Sept
Casa Ybel Resort
A wooden boardwalk leading to a beach with clear skies and calm waters.

3. Shalimar Beach Resort

Shalimar Beach Resort
3.5 star property
West End, 1.5 km from Murex Lakes
9.8 out of 10, Exceptional, (83 reviews)
"Place is great, highly recommend"
United States
Aldo
The price is ฿7,343
฿8,187 total
includes taxes & fees
1 Sept - 2 Sept
Shalimar Beach Resort
A beach with a variety of seashells and pebbles.

4. Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 5.3 km from Murex Lakes
9.2 out of 10, Wonderful, (2,243 reviews)
"We loved the location to all of our stops during our stay we went to museums and preserves and beaches every day"
United States
David Jeffery
The price is ฿5,933
฿7,530 total
includes taxes & fees
1 Sept - 2 Sept
Sanibel Island Beach Resort
A pool area with lounge chairs and umbrellas, a beach with umbrellas and lounge chairs, and palm trees.

5. Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island, 4.8 km from Murex Lakes
8.6 out of 10, Excellent, (2,689 reviews)
"Great place"
United States
moti
The price is ฿13,086
฿16,383 total
includes taxes & fees
1 Sept - 2 Sept
Sundial Beach Resort & Spa
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

6. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
21.2 km from Murex Lakes
9.4 out of 10, Exceptional, (1,637 reviews)
"Great location and breakfast was wonderdul"
United States
Tom
The price is ฿3,378
฿3,767 total
includes taxes & fees
12 Sept - 13 Sept
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
A pathway leading to a pool area with lounge chairs and umbrellas, surrounded by tropical plants and a thatched-roof structure.

7. Sanibel Inn

Sanibel Inn
3.0 star property
East End, 6.3 km from Murex Lakes
9.2 out of 10, Wonderful, (1,000 reviews)
"Property was clean and very friendly staff food and bar on property and restaurant amazing stay"
United States
William
The price is ฿9,967
฿13,203 total
includes taxes & fees
30 Aug - 31 Aug
Sanibel Inn
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

8. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
14.1 km from Murex Lakes
8.8 out of 10, Excellent, (1,003 reviews)
"Very close to the island, affordable, clean, family friendly, okay breakfast, everyone was very nice"
United States
Laura
The price is ฿2,952
฿3,291 total
includes taxes & fees
1 Sept - 2 Sept
Residence Inn by Marriott Fort Myers Sanibel
A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

9. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
10.9 km from Murex Lakes
8.6 out of 10, Excellent, (1,001 reviews)
"The stay was great."
United States
Scott
The price is ฿6,271
฿8,140 total
includes taxes & fees
10 Sept - 11 Sept
Marriott Sanibel Harbour Resort & Spa
A pathway flanked by palm trees and wooden buildings with thatched roofs.

10. Kona Kai Motel

Kona Kai Motel
2.5 star property
Mid Island, 4.7 km from Murex Lakes
9.0 out of 10, Wonderful, (1,010 reviews)
"Good location"
United States
Presley
The price is ฿5,284
฿6,069 total
includes taxes & fees
1 Sept - 2 Sept
Kona Kai Motel
A rustic outdoor bathroom with a wooden deck, a white sink, and various seashells scattered around.

11. Tarpon Tale Inn

Tarpon Tale Inn
3.0 star property
East End, 7.9 km from Murex Lakes
9.6 out of 10, Exceptional, (409 reviews)
"Everything was great- property was well maintained and had everything we needed. Staff was very friendly and helpful. Location to beach, shops, restaurants was really convenient! We will stay there again next time we go to Sanibel!"
United States
Ruth
Tarpon Tale Inn
A modern kitchen with a marble countertop, wooden cabinets, and a built-in pantry.

12. Hyatt Place Fort Myers Estero

Hyatt Place Fort Myers Estero
3.5 star property
29.1 km from Murex Lakes
8.8 out of 10, Excellent, (1,000 reviews)
"Excellent hotel, super accessible and big rooms"
United States
Emmanuel
The price is ฿3,046
฿3,396 total
includes taxes & fees
30 Aug - 31 Aug
Hyatt Place Fort Myers Estero

13. The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 5.4 km from Murex Lakes
9.8 out of 10, Exceptional, (66 reviews)
"Loved staying here, very clean"
United States
Liliana
The price is ฿5,399
฿6,512 total
includes taxes & fees
1 Sept - 2 Sept
The Anchor Inn
A resort with a central pool, multiple lounge areas, and a beach view.

14. Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
12.4 km from Murex Lakes
8.6 out of 10, Excellent, (1,001 reviews)
"very helpful staff and restaurant were excellent."
United States
rick
The price is ฿9,157
฿11,358 total
includes taxes & fees
31 Aug - 1 Sept
Tween Waters Island Resort & Spa
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

15. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
14.7 km from Murex Lakes
8.2 out of 10, Very good, (1,321 reviews)
"We liked the location and the pool. Breakfast was also served and although was not amazing, it was good enough to start off the day. We recommend to any family or people who are looking to go Sanibel Island or Fort Myers Beach and Downtown to stay at this hotel."
United States
Juliana
The price is ฿2,388
฿2,662 total
includes taxes & fees
14 Sept - 15 Sept
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

16. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
17.6 km from Murex Lakes
9.2 out of 10, Wonderful, (1,000 reviews)
"This location is very clean and nice!"
United States
Johny
The price is ฿3,050
฿3,401 total
includes taxes & fees
1 Sept - 2 Sept
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
A beachfront hotel with a pool, beach, and ocean view.

17. DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
15.4 km from Murex Lakes
9.2 out of 10, Wonderful, (1,275 reviews)
"Very nice stay."
United States
Edwin
The price is ฿6,775
฿8,837 total
includes taxes & fees
30 Aug - 31 Aug
DiamondHead Beach Resort
A balcony with a wicker sofa, a yellow table, and a potted plant.

18. Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
16.2 km from Murex Lakes
8.6 out of 10, Excellent, (1,000 reviews)
"Great place to stay"
United States
Rick
The price is ฿3,462
฿3,860 total
includes taxes & fees
30 Aug - 31 Aug
Latitude 26 Waterfront Resort & Marina
A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

19. Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
13.9 km from Murex Lakes
9.4 out of 10, Exceptional, (1,438 reviews)
"Amazing place to stay and relax , stunning location"
United Kingdom
Kate
The price is ฿6,663
฿9,587 total
includes taxes & fees
30 Aug - 31 Aug
Pink Shell Beach Resort and Marina
A modern hotel lobby with a seating area, a reception desk, and a dining area.

20. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
20.2 km from Murex Lakes
8.8 out of 10, Excellent, (1,001 reviews)
"The staff was fantastic and very friendly to work with. Breakfast was wonderful and the hotel room was well kept."
United States
Taylor
The price is ฿3,039
฿3,388 total
includes taxes & fees
20 Sept - 21 Sept
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Murex Lakes

Find the best Murex Lakes areas for the activities you enjoy most.
A coastal scene with a lighthouse, beach, and ocean.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

A coastal scene with a lighthouse, beach, and ocean.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

A coastal scene with a lighthouse, beach, and ocean.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

A cyclist on a paved path alongside a road with cars, palm trees, and a liquor store sign.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach.

Top Murex Lakes Hotel Reviews

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

10/10 Excellent
"Clean room, great staff, delicious breakfast."
Sidney 3-night trip
Posted 3 hours ago
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Frequently asked questions

What's it like in Murex Lakes?
You'll be sure to have fun exploring Sanibel's Murex Lakes neighbourhood.
How many hotels can I expect to find in Murex Lakes?
If you're searching for places to stay in Sanibel, choose from one of Expedia's 16 hotels and other accommodation options in Murex Lakes.
If I need to cancel my hotel reservation in Murex Lakes, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best options available in Murex Lakes.
What is there to do around this Sanibel neighbourhood?
Sanibel Captiva Conservation Foundation, Bailey - Matthews Shell Museum and Sanibel Island Southern Beach are just a few of the places to visit in and around Murex Lakes. When you're sightseeing in Sanibel, Sanibel Historical Museum and Village and BIG Arts Center are also worth a stop.