Search Hotels Near Mission Hope Cancer Center, Santa Maria

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Top Trending Hotels Near Mission Hope Cancer Center

Reception
Hotel Avanti

Hotel Avanti

2.5 star property
2.3 km from Mission Hope Cancer Center
9.0 out of 10, Wonderful, (273)
"The best in Santa Maria "
United States
Josue
The price is ฿2,817
฿3,169 total
includes taxes & fees
7 Dec - 8 Dec
Hotel Avanti
Restaurant
Best Western Plus Big America

Best Western Plus Big America

2.5 star property
2.8 km from Mission Hope Cancer Center
8.8 out of 10, Excellent, (1002)
"great place - clean n comfy beds "
United States
Nancy
The price is ฿3,477
฿3,912 total
includes taxes & fees
7 Dec - 8 Dec
Best Western Plus Big America
Restaurant
Historic Santa Maria Inn

Historic Santa Maria Inn

3.5 star property
2.2 km from Mission Hope Cancer Center
8.4 out of 10, Very good, (1830)
"Our room was awesome, the check in was quick and easy, the bar was open later and we had a great time"
United States
Melody
The price is ฿2,297
฿2,584 total
includes taxes & fees
21 Dec - 22 Dec
Historic Santa Maria Inn
Reception
ECONOMY INN

ECONOMY INN

2.5 star property
2.1 km from Mission Hope Cancer Center
8.0 out of 10, Very good, (72)
"Decent hotel for the price"
United States
ydalid
The price is ฿2,039
฿2,293 total
includes taxes & fees
7 Dec - 8 Dec
ECONOMY INN
Classic Room | Desk, free WiFi
Villa Motel

Villa Motel

2.0 star property
2.4 km from Mission Hope Cancer Center
8.0 out of 10, Very good, (169)
"Staff was very friendly "
United States
erika
The price is ฿2,179
฿2,451 total
includes taxes & fees
9 Dec - 10 Dec
Villa Motel
Premium bedding, in-room safe, blackout curtains, iron/ironing board
Travelodge by Wyndham Santa Maria

Travelodge by Wyndham Santa Maria

2.0 star property
2.9 km from Mission Hope Cancer Center
7.8 out of 10, Good, (1007)
"The guy who check me in was great good customer service "
United States
Angie
The price is ฿3,374
฿3,796 total
includes taxes & fees
14 Dec - 15 Dec
Travelodge by Wyndham Santa Maria
Outdoor pool
Days Inn by Wyndham Santa Maria

Days Inn by Wyndham Santa Maria

2.0 star property
0.8 km from Mission Hope Cancer Center
6.8 out of 10, (1000)
"I was so tired and when i went to check in the guy in the front desk said that check in was at 3 but that if i pay him 40 dollar's more that he would find me a room to check in at that time. I believe it was about noon. "
United States
Francisco Javier
The price is ฿2,413
฿2,715 total
includes taxes & fees
4 Jan - 5 Jan 2026
Days Inn by Wyndham Santa Maria
View from property
Buckboard Motel

Buckboard Motel

2.5 star property
3 km from Mission Hope Cancer Center
6.8 out of 10, (71)
"Excellent place to rest excellent price "
United States
Carlos
The price is ฿1,994
฿2,243 total
includes taxes & fees
7 Dec - 8 Dec
Buckboard Motel
Lobby
Motel 6 Santa Maria, CA - South

Motel 6 Santa Maria, CA - South

2.0 star property
0.5 km from Mission Hope Cancer Center
5.8 out of 10, (510)
"Room was nice and the owner and staff were helpful and kind."
United States
Jason
The price is ฿2,440
฿2,745 total
includes taxes & fees
1 Jan - 2 Jan 2026
Motel 6 Santa Maria, CA - South
Reception
Hampton Inn & Suites Santa Maria

Hampton Inn & Suites Santa Maria

2.5 star property
3.7 km from Mission Hope Cancer Center
9.4 out of 10, Exceptional, (1000)
"Lovely hotel"
United States
Adrian
The price is ฿3,420
฿3,854 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn & Suites Santa Maria
Front of property – evening/night
Wine Stone Inn

Wine Stone Inn

5.0 star property
10.2 km from Mission Hope Cancer Center
9.8 out of 10, Exceptional, (597)
"Room was super clean and roomy ...bed was very comfortable! Love the decor in the entire hotel. Staff was friendly and accommodating. "
United States
shannon
The price is ฿4,565
฿5,433 total
includes taxes & fees
7 Dec - 8 Dec
Wine Stone Inn
Property amenity
Fairfield Inn & Suites by Marriott Santa Maria

Fairfield Inn & Suites by Marriott Santa Maria

2.5 star property
3.3 km from Mission Hope Cancer Center
8.6 out of 10, Excellent, (718)
"Staff for breakfast"
United States
Kiari
The price is ฿3,573
฿4,027 total
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn & Suites by Marriott Santa Maria
Restaurant
Homewood Suites by Hilton Santa Maria

Homewood Suites by Hilton Santa Maria

3.0 star property
3.5 km from Mission Hope Cancer Center
8.6 out of 10, Excellent, (31)
"Friendly staff and nice hotel."
United States
Elisa
The price is ฿3,803
฿4,286 total
includes taxes & fees
4 Jan - 5 Jan 2026
Homewood Suites by Hilton Santa Maria
Studio Suite, 2 Double Beds | Desk, blackout curtains, iron/ironing board, free cots/infant beds
Candlewood Suites Santa Maria by IHG

Candlewood Suites Santa Maria by IHG

2.5 star property
3.3 km from Mission Hope Cancer Center
8.6 out of 10, Excellent, (1000)
"Nice, clean hotel "
United States
janice
The price is ฿3,158
฿3,553 total
includes taxes & fees
14 Dec - 15 Dec
Candlewood Suites Santa Maria by IHG
Check-in/check-out kiosk
Solaire Inn & Suites

Solaire Inn & Suites

2.5 star property
3.6 km from Mission Hope Cancer Center
8.2 out of 10, Very good, (1001)
"Clean Staff very helpful "
United States
Sally
The price is ฿2,125
฿2,390 total
includes taxes & fees
7 Dec - 8 Dec
Solaire Inn & Suites
Front of property
Kaleidoscope Inn & Gardens

Kaleidoscope Inn & Gardens

2.5 star property
11.5 km from Mission Hope Cancer Center
8.4 out of 10, Very good, (206)
"Room was clean and the bathroom was excellent "
United States
Michelle
The price is ฿6,604
฿7,430 total
includes taxes & fees
10 Dec - 11 Dec
Kaleidoscope Inn & Gardens
Pet-friendly amenities
Motel 6 Santa Maria, CA - North

Motel 6 Santa Maria, CA - North

2.0 star property
3.4 km from Mission Hope Cancer Center
7.4 out of 10, Good, (1020)
"Room was clean, staff was friendly, has free parking, complimentary coffee and tea in the morning. This was my second time staying here. "
United States
Katrina
The price is ฿1,762
฿1,988 total
includes taxes & fees
7 Dec - 8 Dec
Motel 6 Santa Maria, CA - North
Outdoor pool
Radisson Hotel Santa Maria

Radisson Hotel Santa Maria

3.5 star property
6.8 km from Mission Hope Cancer Center
7.6 out of 10, Good, (1317)
"Good location "
United States
Anthony
The price is ฿3,146
฿3,539 total
includes taxes & fees
4 Jan - 5 Jan 2026
Radisson Hotel Santa Maria
Desk, free WiFi, bed sheets, wheelchair access
Colonial Motel

Colonial Motel

2.0 star property
3.4 km from Mission Hope Cancer Center
6.2 out of 10, (161)
"Affordable "
United States
Albert
The price is ฿2,712
฿3,051 total
includes taxes & fees
7 Dec - 8 Dec
Colonial Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mission Hope Cancer Center Hotel Reviews

Hotel Avanti

Hotel Avanti

10/10 Excellent
"Clean room. Friendly and helpful staff."
dohnanyi 2-night trip
Posted 2 days ago
Hotel Avanti
SeaCrest OceanFront Hotel

SeaCrest OceanFront Hotel

10/10 Excellent
"Our room had a large balcony and from it during daylight hours we could see the ocean. The hotel is on a bluff but has stairs where guests can walk down to Pismo Beach and walk for miles on the pristine sand and then on the Boardwalk. You can also walk to the cute shops and onto the Pismo Pier. The pier has a Christmas tree lit up at night that you can see from the hotel."
Janet 3-night trip
Posted 3 days ago
SeaCrest OceanFront Hotel

Hotels near other Mission Hope Cancer Center attractions

Pacific Conservatory Theatre

You can enjoy a show at Pacific Conservatory Theatre on your trip to Santa Maria. While in this romantic area, you can savour the top-notch restaurants.
See properties

Simas Park

After visiting Simas Park, make a plan to see the other sights and activities in Santa Maria. While in this romantic area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Mission Hope Cancer Center?
Mission Hope Cancer Center is located in a family-friendly area of Santa Maria known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 6 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mission Hope Cancer Center?
Historic Santa Maria Inn is one of the top choices for your stay based on our traveller data, and this hotel offers 2 bars and a restaurant. It's located 1.4 mi (2.2 km) from Mission Hope Cancer Center. Other good options within 5 miles include Hampton Inn & Suites Santa Maria and Hotel Avanti.
How many hotels will I be able to find near Mission Hope Cancer Center?
Expedia has 6 hotels and other accommodation options within a mile from Mission Hope Cancer Center.
If I need to cancel the hotel reservation for my stay near Mission Hope Cancer Center, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the top deals on offer near Mission Hope Cancer Center.
What can I see and do near Mission Hope Cancer Center?
Study the collections at Santa Maria Valley Historical Society, Natural History Museum or Santa Maria Museum of Flight. You can enjoy live performances at Pacific Conservatory Theatre and Santa Maria Civic Theatre. Santa Maria Valley Discovery Museum, Rancho Bowl and Santa Maria Fairpark are fun stops for the whole family while you're in town.