Search Hotels in Mission Bay, San Diego

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mission Bay hotels

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.6 out of 10, Excellent, (1,444 reviews)
"Great resort!"
United States
Jean-Michelle
The price is ฿5,985
฿8,608 total
includes taxes & fees
27 May - 28 May
San Diego Mission Bay Resort

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.8 out of 10, Excellent, (2,601 reviews)
"Phenomenal stay!! "
United States
Raymond
The price is ฿7,982
฿10,904 total
includes taxes & fees
2 Jun - 3 Jun
Paradise Point Resort & Spa

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay
9.0 out of 10, Wonderful, (4,366 reviews)
"NICE PLACE TO STAY"
United States
René
The price is ฿6,175
฿8,037 total
includes taxes & fees
27 May - 28 May
The Dana on Mission Bay

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1,621 reviews)
"The only place I will stay at in San diego! Clean hotel, great amenities, wonderful staff."
United States
Hanna
The price is ฿6,011
฿8,638 total
includes taxes & fees
26 May - 27 May
Hyatt Regency Mission Bay Spa and Marina

Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
5.3 km from Mission Bay
9.2 out of 10, Wonderful, (1,722 reviews)
"Good location, clean room and nice staff. A great place to stay."
United States
Patricia
The price is ฿5,804
฿6,671 total
includes taxes & fees
7 Jun - 8 Jun
Hampton Inn & Suites San Diego Airport Liberty Station

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.7 km from Mission Bay
9.2 out of 10, Wonderful, (3,831 reviews)
"Great resort "
United States
Ines
The price is ฿4,868
฿5,364 total
includes taxes & fees
24 May - 25 May
Best Western Plus Marina Gateway Hotel

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
28.6 km from Mission Bay
9.0 out of 10, Wonderful, (1,279 reviews)
"Everything was very pleasant,the place was super clean, and the breakfast was delicious👍"
United States
Nancy
The price is ฿3,709
฿4,219 total
includes taxes & fees
28 May - 29 May
Best Western Americana Inn

Ramada by Wyndham San Diego Poway Miramar

Ramada by Wyndham San Diego Poway Miramar
2.0 star property
24.7 km from Mission Bay
7.2 out of 10, Good, (1,004 reviews)
"Well maintained property, staff were professional and very nice"
United States
Cherie
The price is ฿2,762
฿3,039 total
includes taxes & fees
25 May - 26 May
Ramada by Wyndham San Diego Poway Miramar

Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
20.6 km from Mission Bay
8.2 out of 10, Very good, (1,511 reviews)
"Laundry room was extremely clean breakfast pretty nice staff was excellent "
United States
Victoria
The price is ฿3,414
฿3,763 total
includes taxes & fees
14 Jun - 15 Jun
Comfort Inn Chula Vista San Diego South

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
20.7 km from Mission Bay
8.6 out of 10, Excellent, (1,619 reviews)
"Great stay"
United States
Helda
The price is ฿3,499
฿3,849 total
includes taxes & fees
25 May - 26 May
La Quinta Inn by Wyndham San Diego Chula Vista

Days Inn by Wyndham San Diego-East/El Cajon

Days Inn by Wyndham San Diego-East/El Cajon
2.0 star property
25.7 km from Mission Bay
7.8 out of 10, Good, (1,003 reviews)
"Great place definitely recommend"
United States
Trenton
The price is ฿2,911
฿3,208 total
includes taxes & fees
25 May - 26 May
Days Inn by Wyndham San Diego-East/El Cajon

Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista
3.0 star property
29.6 km from Mission Bay
9.8 out of 10, Exceptional, (1,101 reviews)
"Nice place good food for breakfast 👍"
United States
Paul
The price is ฿6,145
฿6,772 total
includes taxes & fees
7 Jun - 8 Jun
Ayres Hotel San Diego South - Chula Vista

TownePlace Suites by Marriott San Diego Airport/Liberty Station

TownePlace Suites by Marriott San Diego Airport/Liberty Station
3.0 star property
5.2 km from Mission Bay
9.0 out of 10, Wonderful, (1,003 reviews)
"Love it great place"
United States
Derek
The price is ฿6,175
฿7,098 total
includes taxes & fees
25 May - 26 May
TownePlace Suites by Marriott San Diego Airport/Liberty Station

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
4.8 km from Mission Bay
9.2 out of 10, Wonderful, (1,062 reviews)
"Staff was so great nice rooms really great stay"
United States
Amelia
The price is ฿4,607
฿5,295 total
includes taxes & fees
26 May - 27 May
Holiday Inn Express San Diego Airport - Old Town by IHG

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
6 km from Mission Bay
8.4 out of 10, Very good, (3,542 reviews)
"Great breakfast and beautiful view!"
Canada
michelle
The price is ฿5,521
฿7,999 total
includes taxes & fees
26 May - 27 May
Sheraton San Diego Resort

Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego
2.5 star property
21.6 km from Mission Bay
8.4 out of 10, Very good, (1,005 reviews)
"Nice place close to I8."
United States
Farrell
The price is ฿4,268
฿4,695 total
includes taxes & fees
31 May - 1 Jun
Best Western Plus La Mesa San Diego

Best Western San Diego/Miramar Hotel

Best Western San Diego/Miramar Hotel
2.5 star property
16.1 km from Mission Bay
8.0 out of 10, Very good, (1,333 reviews)
"Wonderful, kind staff and good breakfast"
United States
Kimberly
The price is ฿3,231
฿3,714 total
includes taxes & fees
28 May - 29 May
Best Western San Diego/Miramar Hotel

Country Inn & Suites by Radisson, San Diego North, CA

Country Inn & Suites by Radisson, San Diego North, CA
3.0 star property
13.8 km from Mission Bay
9.0 out of 10, Wonderful, (1,495 reviews)
"Comfortable place to stay with good breakfast."
United States
David
The price is ฿5,245
฿6,029 total
includes taxes & fees
28 May - 29 May
Country Inn & Suites by Radisson, San Diego North, CA

Courtyard by Marriott San Diego El Cajon

Courtyard by Marriott San Diego El Cajon
3.0 star property
24.5 km from Mission Bay
9.2 out of 10, Wonderful, (1,003 reviews)
"Really nice staff and great hotel!"
Canada
Shana
The price is ฿5,107
฿5,628 total
includes taxes & fees
31 May - 1 Jun
Courtyard by Marriott San Diego El Cajon

Lamplighter Inn & Suites at SDSU

Lamplighter Inn & Suites at SDSU
2.5 star property
15.3 km from Mission Bay
9.0 out of 10, Wonderful, (1,427 reviews)
"Great location good continental breakfast."
United States
Michael
The price is ฿4,349
฿4,903 total
includes taxes & fees
25 May - 26 May
Lamplighter Inn & Suites at SDSU
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach and Dog Beach.

Top Mission Bay Hotel Reviews

Frequently asked questions

What is Mission Bay like?
You'll be sure to have fun exploring San Diego's Mission Bay neighbourhood. Looking for sights you might find in a travel guide about Mission Bay? Consider a visit to Mission Bay while you're in the neighbourhood.
What's a favourite hotel to stay in Mission Bay?
Based on our traveller data, Paradise Point Resort & Spa is one of the top choices for your stay in Mission Bay. This resort offers a marina and 5 outdoor pools. Other good options for your stay in the neighbourhood include Hyatt Regency Mission Bay Spa and Marina and The Dana on Mission Bay.
How many hotels should I expect to find in the Mission Bay area?
If you're searching for places to stay in San Diego, Expedia has something to meet your needs with 46 Mission Bay hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view top deals in Mission Bay.
What is there to do around this San Diego neighbourhood?
Enjoy a stroll along the shore at Mission and Pacific Beaches, Ski Beach and Crown Point Shores while you're in Mission Bay. You could also plan a visit to Mission Bay or North Cove Beach while you're in the neighbourhood. Mission Beach and Hotel Circle are some popular places to visit in the area around Mission Bay. When you're sightseeing in San Diego, Bahia Point Beach and Bay City Brewing Co. are also worth a stop.