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Top Trending Hotels Near Mission Bay, San Diego

2 outdoor pools, a heated pool, pool loungers
The Dana on Mission Bay

The Dana on Mission Bay

3.5 star property
Mission Bay
9.0 out of 10, Wonderful, (3903)
"Staff was great, room was spotless, and map was easy to follow."
United States
Rosa
The price is ฿4,755
฿6,103 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Dana on Mission Bay
Exterior
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4.0 star property
Mission Bay
8.4 out of 10, Very good, (1567)
"Loved our stay "
United States
Jeremy
The price is ฿3,705
฿5,947 total
includes taxes & fees
16 Dec - 17 Dec
Hyatt Regency Mission Bay Spa and Marina
Outdoor pool, open 7:00 AM to 10:00 PM, pool cabanas (surcharge)
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4.0 star property
Mission Bay
8.4 out of 10, Very good, (1308)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is ฿5,712
฿8,004 total
includes taxes & fees
8 Dec - 9 Dec
San Diego Mission Bay Resort
Property grounds
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4.0 star property
Mission Bay
8.6 out of 10, Excellent, (2347)
"Amazing place!"
United States
Barak Ben
The price is ฿4,128
฿6,433 total
includes taxes & fees
8 Dec - 9 Dec
Paradise Point Resort & Spa
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
8 km from Mission Bay
8.4 out of 10, Very good, (6069)
"Always an amazing stay"
United States
Jana
The price is ฿4,313
฿5,926 total
includes taxes & fees
9 Dec - 10 Dec
Wyndham San Diego Bayside
Outdoor pool
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4.0 star property
Gaslamp Quarter, 9.7 km from Mission Bay
9.0 out of 10, Wonderful, (3141)
"Great stay"
United States
Laurence
The price is ฿5,428
฿7,760 total
includes taxes & fees
21 Dec - 22 Dec
Hard Rock Hotel San Diego
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 star property
16.7 km from Mission Bay
9.2 out of 10, Wonderful, (3491)
"Clean room nice staff right off of the freeway. "
United States
Olivia
The price is ฿3,705
฿4,083 total
includes taxes & fees
14 Dec - 15 Dec
Best Western Plus Marina Gateway Hotel
Rooftop terrace
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 9.1 km from Mission Bay
8.8 out of 10, Excellent, (2084)
"Room was spotless and location great. "
United States
James
The price is ฿4,435
฿5,143 total
includes taxes & fees
14 Dec - 15 Dec
Palihotel San Diego Gaslamp Quarter
Serves dinner and happy hour
The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
Marina District, 9.3 km from Mission Bay
9.0 out of 10, Wonderful, (2696)
"Clean facilities and friendly staff!"
United States
EMMA
The Horton Grand, Downtown/Gaslamp Quarter
Exterior
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Gaslamp Quarter, 9.6 km from Mission Bay
9.0 out of 10, Wonderful, (1228)
"Very nice clean room and amenities and staff was pleasant and we love the location. "
United States
Arnold
The price is ฿4,374
฿5,072 total
includes taxes & fees
14 Dec - 15 Dec
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Property entrance
The Bristol Hotel San Diego

The Bristol Hotel San Diego

3.5 star property
8.7 km from Mission Bay
8.6 out of 10, Excellent, (1442)
"So clean, Very Nice staff, convenient location ! "
United States
Cindy
The Bristol Hotel San Diego
Garden
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4.0 star property
5.3 km from Mission Bay
9.2 out of 10, Wonderful, (2954)
"Friendly, staff was very helpful, great size rooms, and over all was an amazing stay"
United States
Naya
The price is ฿4,855
฿5,581 total
includes taxes & fees
8 Dec - 9 Dec
Legacy Resort Hotel & Spa
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

3.5 star property
Gaslamp Quarter, 9 km from Mission Bay
9.0 out of 10, Wonderful, (1006)
"Great room, clean, spacious and quiet. "
United States
Maria
The price is ฿3,542
฿4,029 total
includes taxes & fees
9 Dec - 10 Dec
Gaslamp Plaza Suites
Front of property
The Sofia Hotel

The Sofia Hotel

3.5 star property
8.7 km from Mission Bay
8.4 out of 10, Very good, (1652)
"Great location and history to the hotel "
United States
Stephanie
The Sofia Hotel
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Gaslamp Quarter, 9.4 km from Mission Bay
9.4 out of 10, Exceptional, (1007)
"The room was immaculate, the staff were helpful and friendly and our stay was so wonderful. "
United States
Samantha Erin
The price is ฿3,877
฿5,417 total
includes taxes & fees
26 Dec - 27 Dec
Staypineapple, Hotel Z, Gaslamp San Diego
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4.0 star property
Marina District, 9.2 km from Mission Bay
9.2 out of 10, Wonderful, (1939)
"Great hotel"
United States
Farzana
The price is ฿5,074
฿7,561 total
includes taxes & fees
18 Dec - 19 Dec
Marriott Marquis San Diego Marina
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillow-top beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
8.2 km from Mission Bay
8.8 out of 10, Excellent, (717)
"Great staff, great location, great value. "
United States
Juan
The price is ฿3,293
฿3,818 total
includes taxes & fees
15 Dec - 16 Dec
The DEXTRO Little Italy, BW Premier Collection
Exterior
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 star property
6.8 km from Mission Bay
9.2 out of 10, Wonderful, (3171)
"Great stay and location!"
United States
Jason
The price is ฿3,475
฿3,994 total
includes taxes & fees
8 Dec - 9 Dec
Bay Club Hotel & Marina
Outdoor pool, a heated pool
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
5.5 km from Mission Bay
8.0 out of 10, Very good, (2427)
"Front desk staff was kind, knowledgeable and efficient "
United States
Elizabeth
The price is ฿2,821
฿3,242 total
includes taxes & fees
9 Dec - 10 Dec
Days Inn by Wyndham San Diego Hotel Circle
Meeting facility
The Westin San Diego Bayview

The Westin San Diego Bayview

4.0 star property
8.5 km from Mission Bay
8.6 out of 10, Excellent, (1049)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is ฿4,314
฿5,927 total
includes taxes & fees
19 Dec - 20 Dec
The Westin San Diego Bayview
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Pacific Beach Park showing a beach

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Belmont Park featuring a park and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Mission Bay Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"The room was pretty great there was a nice view of the town, but we could see homeless people in tents sleeping, so there was that. Front desk was amazing. The bar downstairs was great my husband went down and had a drink and watched some sports. Overall a great trip: for a three-star hotel, it was fantastic! Price of room was average, but the parking was a little much at $37.50 for one 24 hour peri[parking fr 9:00 p.m. to 5:00 a.m. was steep."
Jennifer 1-night trip
Posted 8 hours ago
The DEXTRO Little Italy, BW Premier Collection

Explore a world of travel with Expedia

Frequently asked questions

What is Mission Bay like?
You'll be sure to have fun exploring San Diego's Mission Bay neighbourhood. Looking for sights you might find in a travel guide about Mission Bay? Consider a visit to Mission Bay while you're in the neighbourhood.
What's a favourite hotel to stay in Mission Bay?
Based on Expedia customer reviews, Paradise Point Resort & Spa is the highest ranked property in Mission Bay. This resort offers a marina and 5 outdoor pools. Other favourite options in the area include San Diego Mission Bay Resort and The Dana on Mission Bay.
How many hotels should I expect to find in the Mission Bay area?
If you're searching for places to stay in San Diego, Expedia has something to meet your needs with 46 Mission Bay hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view top deals in Mission Bay.
What is there to do around this San Diego neighbourhood?
Enjoy a stroll along the shore at Mission and Pacific Beaches, Ski Beach and Crown Point Shores while you're in Mission Bay. You could also plan a visit to Mission Bay or Mission Bay Golf Course while you're in the neighbourhood. Hotel Circle, North Cove Beach and Bahia Point Beach are just a few of the places to visit in and around Mission Bay. When you're sightseeing in San Diego, Bay City Brewing Co. and Sail Bay are also worth a stop.