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Our top choices for Midtown hotels

Element St. Louis Midtown

Element St. Louis Midtown
3.0 star property
Midtown
9.0 out of 10, Wonderful, (693 reviews)
"Hotel staff and the valet staff were very helpful. This hotel is in an excellent location and there are many places to walk to for food and shopping. Breakfast was amazing with a lot of choices."
United States
Lori
The price is ฿4,440
฿5,192 total
includes taxes & fees
29 Mar - 30 Mar
Element St. Louis Midtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.8 out of 10, Good, (1,001 reviews)
"Beds are nice. Bedrooms are clean. Breakfast was good. Front end staff was attentive and kind. The floors, carpets and elevators need better cleaning"
United States
Maria
The price is ฿3,618
฿4,303 total
includes taxes & fees
15 Apr - 16 Apr
Residence Inn by Marriott St Louis Downtown

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
16 km from Midtown
9.2 out of 10, Wonderful, (1,003 reviews)
"I have always been a fan of the hyatt boutique properties. Great place to stay before an early flight and just enough amenities for comfort. "
United States
Rick
The price is ฿3,819
฿4,689 total
includes taxes & fees
29 Mar - 30 Mar
Hyatt Select St. Louis Airport

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
27.6 km from Midtown
8.6 out of 10, Excellent, (678 reviews)
"Room was great,staff friendly! All together a great stay."
United States
Zachary
The price is ฿4,243
฿4,879 total
includes taxes & fees
24 Mar - 25 Mar
Country Hearth Inn & Suites Edwardsville St. Louis

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
25.8 km from Midtown
9.6 out of 10, Exceptional, (1,003 reviews)
"Very clean place with great food and friendly staff. "
Canada
Kara
The price is ฿3,782
฿4,425 total
includes taxes & fees
3 Apr - 4 Apr
Drury Inn & Suites Southwest St. Louis

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
29.4 km from Midtown
9.4 out of 10, Exceptional, (745 reviews)
"Shower was amazing, clean room, nice staff, decent breakfast"
United States
Paula
The price is ฿4,079
฿4,526 total
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express Troy by IHG

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
17.2 km from Midtown
9.2 out of 10, Wonderful, (1,563 reviews)
The price is ฿3,560
฿4,192 total
includes taxes & fees
5 Apr - 6 Apr
Wingate by Wyndham St. Louis Airport

Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
16.7 km from Midtown
9.2 out of 10, Wonderful, (1,154 reviews)
"Friendly staff, clean and convenient"
United States
Bethany
The price is ฿3,782
฿4,438 total
includes taxes & fees
29 Mar - 30 Mar
Drury Inn & Suites St. Louis Airport

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
23.2 km from Midtown
8.0 out of 10, Very good, (1,153 reviews)
"Clean room, very friendly staff."
United States
Jordan
The price is ฿2,936
฿3,391 total
includes taxes & fees
29 Mar - 30 Mar
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
11.9 km from Midtown
9.0 out of 10, Wonderful, (1,491 reviews)
"Great front desk assistance and nice facility with some non-smoking areas!"
United States
Kimberly
The price is ฿3,552
฿4,614 total
includes taxes & fees
30 Mar - 31 Mar
River City Casino & Hotel

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
17.3 km from Midtown
9.4 out of 10, Exceptional, (2,876 reviews)
"Great stay, super clean and friendly staff."
United States
Edmarie
The price is ฿2,960
฿3,485 total
includes taxes & fees
29 Mar - 30 Mar
Pear Tree Inn St. Louis Airport

The Principal Hotel

The Principal Hotel
3.5 star property
21.4 km from Midtown
9.8 out of 10, Exceptional, (216 reviews)
"I love staying here whenever i come to town."
United States
bonnie
The price is ฿3,711
฿4,118 total
includes taxes & fees
29 Mar - 30 Mar
The Principal Hotel

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 3.4 km from Midtown
9.4 out of 10, Exceptional, (3,354 reviews)
"Wi-fi was great, location was great and staff were really nice!"
United States
Myra L.
The price is ฿5,328
฿6,230 total
includes taxes & fees
29 Mar - 30 Mar
Drury Plaza Hotel St. Louis at the Arch

Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
2.5 star property
Dogtown, 4.8 km from Midtown
9.2 out of 10, Wonderful, (1,005 reviews)
"Staff very friendly and hotel was very nice."
United States
Daniel Richard
The price is ฿4,019
฿4,739 total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn O'Fallon

Hampton Inn O'Fallon
2.5 star property
26.3 km from Midtown
9.2 out of 10, Wonderful, (831 reviews)
"We had a peaceful, clean and friendly stay. Very nice location. "
United States
Carl
The price is ฿3,218
฿3,732 total
includes taxes & fees
4 Apr - 5 Apr
Hampton Inn O'Fallon

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
27.8 km from Midtown
9.2 out of 10, Wonderful, (853 reviews)
"Very good staff and great breakfast service."
United States
Denise
The price is ฿4,802
฿5,522 total
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express & Suites Edwardsville by IHG

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
24.2 km from Midtown
8.4 out of 10, Very good, (832 reviews)
"Very friendly staff, comfortable room and convenient location "
United States
Aimee
The price is ฿3,581
฿4,118 total
includes taxes & fees
16 Apr - 17 Apr
Comfort Inn Edwardsville - St. Louis

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
29.2 km from Midtown
8.0 out of 10, Very good, (1,005 reviews)
"Great for the price"
United States
MARK
The price is ฿2,368
฿2,628 total
includes taxes & fees
24 Mar - 25 Mar
Super 8 by Wyndham Troy IL/St. Louis Area

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
21 km from Midtown
8.6 out of 10, Excellent, (1,870 reviews)
"Great stay! "
United States
Andre
The price is ฿2,142
฿2,618 total
includes taxes & fees
5 Apr - 6 Apr
Motel 6 Hazelwood, MO

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
28.4 km from Midtown
8.8 out of 10, Excellent, (1,007 reviews)
"Great breakfast buffet and fresh made omelettes, room was very clean and comfy!"
United States
Kelley
The price is ฿4,019
฿4,619 total
includes taxes & fees
5 Apr - 6 Apr
Embassy Suites by Hilton St. Louis St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and Enterprise Center.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Top Midtown Hotel Reviews

Frequently asked questions

What is Midtown like?
Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on Expedia customer reviews, Element St. Louis Midtown is the highest ranked property in Midtown. This hotel offers free breakfast and an indoor pool. Another top choice in the area is Residence Inn by Marriott St Louis Downtown.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 35 Midtown hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.
What are the top things to see and do in Midtown?
Explore Midtown's landmarks such as Washington Avenue Historic District, Scott Joplin House State Historic Site and Samuel Cupples House and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighbourhood. Favourite places to visit in the surrounding area include St. Louis Union Station, Enterprise Center and Busch Stadium. While you're out sightseeing, Gateway Arch and .ZACK Theater are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.

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