Lodging Image

Search Hotels in Midtown, St. Louis

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Star rating

Our top choices for Midtown hotels

Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown
3.0 star property
Midtown
9.0 out of 10, Wonderful, (763 reviews)
"Nice stay. Staff was nice."
United States
Regina
The price is ฿4,450
฿5,204 total
includes taxes & fees
12 Jul - 13 Jul
Element by Marriott St. Louis Midtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.8 out of 10, Good, (1,002 reviews)
"Great, convenient location. Rooms were nice and complimentary breakfast was great. "
United States
Marty
The price is ฿3,890
฿4,626 total
includes taxes & fees
13 Jul - 14 Jul
Residence Inn by Marriott St Louis Downtown

The Principal Hotel

The Principal Hotel
3.5 star property
21.4 km from Midtown
9.6 out of 10, Exceptional, (305 reviews)
"Great hotel and nice staff!"
United States
Michelle
The price is ฿3,719
฿4,127 total
includes taxes & fees
23 Jun - 24 Jun
The Principal Hotel

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
23.2 km from Midtown
7.8 out of 10, Good, (1,373 reviews)
"Will definitely stay again!"
United States
Trevor
The price is ฿3,110
฿3,592 total
includes taxes & fees
22 Jun - 23 Jun
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia
2.5 star property
21.2 km from Midtown
8.6 out of 10, Excellent, (513 reviews)
"The staff was all friendly & very helpful. The room was very comfortable & clean. Breakfast had many choices & was delicious!!! Definitely staying here on all our trips in this area."
United States
Angie
The price is ฿3,484
฿3,867 total
includes taxes & fees
28 Jun - 29 Jun
Hampton Inn St. Louis - Columbia

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
3.0 star property
17.2 km from Midtown
9.2 out of 10, Wonderful, (1,657 reviews)
"Excelent breakfast, clean room, friendly staff."
United States
Irmaris
The price is ฿3,783
฿4,454 total
includes taxes & fees
5 Jul - 6 Jul
Wingate by Wyndham St. Louis Airport

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
27.6 km from Midtown
8.6 out of 10, Excellent, (715 reviews)
"We had a great stay and the breakfast was really good."
United States
Tonya
The price is ฿4,252
฿4,889 total
includes taxes & fees
1 Jul - 2 Jul
Country Hearth Inn & Suites Edwardsville St. Louis

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
17.3 km from Midtown
9.4 out of 10, Exceptional, (3,036 reviews)
"Close to airport, good rate."
United States
Gary
The price is ฿3,461
฿4,075 total
includes taxes & fees
29 Jun - 30 Jun
Pear Tree Inn St. Louis Airport

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
11.9 km from Midtown
9.2 out of 10, Wonderful, (1,622 reviews)
"Would stay again in a heartbeat!"
United States
Austin
The price is ฿3,164
฿4,163 total
includes taxes & fees
29 Jun - 30 Jun
River City Casino & Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
6.8 km from Midtown
9.0 out of 10, Wonderful, (1,972 reviews)
"Super convenient location, friendly staff, cool decor! Will definitely stay here again."
United States
Lindsay
The price is ฿4,406
฿5,240 total
includes taxes & fees
1 Jul - 2 Jul
Moonrise Hotel

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
24.8 km from Midtown
9.6 out of 10, Exceptional, (1,002 reviews)
"Excellent pool and hot tub, super friendly staff, evening reception with snacks and drinks and breakfast were all fantastic. A help yourself soda machine was awesome!"
United States
julie
The price is ฿4,219
฿4,877 total
includes taxes & fees
5 Jul - 6 Jul
Drury Inn & Suites St. Louis Arnold

Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport
2.5 star property
Woodson Terrace, 16.3 km from Midtown
8.8 out of 10, Excellent, (173 reviews)
"Very clean room, great breakfast, friendly staff"
United States
Alana
The price is ฿4,717
฿5,630 total
includes taxes & fees
8 Jul - 9 Jul
Hampton Inn By Hilton St Louis Airport

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
24.2 km from Midtown
8.4 out of 10, Very good, (873 reviews)
"Enjoyed my stay! Hotel was nice and convenient"
United States
Renita M.
The price is ฿3,446
฿3,963 total
includes taxes & fees
4 Jul - 5 Jul
Comfort Inn Edwardsville - St. Louis

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 3.4 km from Midtown
8.6 out of 10, Excellent, (4,138 reviews)
"This was one of the nicest hotels I have ever stayed at for a very affordable price. We would definitely stay here again."
United States
Elisha
The price is ฿5,241
฿6,181 total
includes taxes & fees
28 Jun - 29 Jun
Hyatt Regency St. Louis at The Arch

The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
7.7 km from Midtown
9.4 out of 10, Exceptional, (581 reviews)
"Great location, restaurant was good too. Staff was nice."
United States
RICHOO Bijoo
The price is ฿4,457
฿5,125 total
includes taxes & fees
1 Jul - 2 Jul
The Knight Center at Washington University

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
23.3 km from Midtown
7.8 out of 10, Good, (1,249 reviews)
"nice place"
United States
diana
The price is ฿2,942
฿3,398 total
includes taxes & fees
22 Jun - 23 Jun
Wingate by Wyndham St. Louis/Fenton Route 66

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
29.2 km from Midtown
8.0 out of 10, Very good, (1,003 reviews)
"Good customer service well put together hotel"
United States
Donta
The price is ฿2,242
฿2,488 total
includes taxes & fees
29 Jun - 30 Jun
Super 8 by Wyndham Troy IL/St. Louis Area

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
2.5 star property
24.8 km from Midtown
9.4 out of 10, Exceptional, (1,006 reviews)
"Property was clean, there was plenty of breakfast and the staff was very friendly."
United States
Eliza
The price is ฿2,967
฿3,429 total
includes taxes & fees
5 Jul - 6 Jul
Pear Tree Inn St. Louis Arnold

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
25.8 km from Midtown
8.4 out of 10, Very good, (2,187 reviews)
"Wonderful stay"
United States
Elaina
The price is ฿3,428
฿4,478 total
includes taxes & fees
25 Jun - 26 Jun
Hollywood Casino & Hotel St. Louis

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 3.4 km from Midtown
9.6 out of 10, Exceptional, (3,502 reviews)
"Wonderful place to stay in St Louis! Great location, great staff, wonderful breakfast buffet, and reasonably priced!"
United States
Christopher
The price is ฿5,604
฿6,552 total
includes taxes & fees
28 Jun - 29 Jun
Drury Plaza Hotel St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Top Midtown Hotel Reviews

Frequently asked questions

What is Midtown like?
Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on our traveller data, Residence Inn by Marriott St Louis Downtown is one of the top choices for your stay in Midtown. This hotel is a short 14-minute walk from St. Louis University, and it offers an indoor pool and in-room kitchens. Another good choice for your stay in the neighbourhood is Element by Marriott St. Louis Midtown.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 34 Midtown hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.
What are the top things to see and do in Midtown?
Explore Midtown's landmarks such as Washington Avenue Historic District, Scott Joplin House State Historic Site and Samuel Cupples House and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighbourhood. Favourite places to visit in the surrounding area include St. Louis Union Station, Busch Stadium and Gateway Arch. While you're out sightseeing, .ZACK Theater and Red Flag are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.

Explore a world of travel with Expedia