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Our top choices for Midtown hotels

Element St. Louis Midtown

Element St. Louis Midtown
3.0 star property
Midtown
9.0 out of 10, Wonderful, (734 reviews)
"Clean room and spacious "
United States
Vivian
The price is ฿4,350
฿5,086 total
includes taxes & fees
21 May - 22 May
Element St. Louis Midtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.8 out of 10, Good, (1,002 reviews)
"Great, convenient location. Rooms were nice and complimentary breakfast was great. "
United States
Marty
The price is ฿3,544
฿4,215 total
includes taxes & fees
26 May - 27 May
Residence Inn by Marriott St Louis Downtown

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
16 km from Midtown
9.2 out of 10, Wonderful, (1,014 reviews)
"Rooms were outstanding and breakfast was good"
United States
james
The price is ฿3,802
฿4,666 total
includes taxes & fees
2 Jun - 3 Jun
Hyatt Select St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
17.3 km from Midtown
9.4 out of 10, Exceptional, (2,981 reviews)
"Room was quiet, good breakfast, easy access to airport, also offer long term parking and airport shuttle."
United States
LeAndra
The price is ฿3,222
฿3,793 total
includes taxes & fees
10 May - 11 May
Pear Tree Inn St. Louis Airport

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
27.6 km from Midtown
8.6 out of 10, Excellent, (696 reviews)
"This place is independently owned and the owners show pride. The room and common areas were spotless. The breakfast had choices and was very good. The mattress must be new, it was the most comfortable mattress I’ve slept on. I will stay here again. "
United States
Eric
The price is ฿4,640
฿5,335 total
includes taxes & fees
13 May - 14 May
Country Hearth Inn & Suites Edwardsville St. Louis

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
27.8 km from Midtown
9.2 out of 10, Wonderful, (863 reviews)
"Very good staff and great breakfast service."
United States
Denise
The price is ฿4,640
฿5,335 total
includes taxes & fees
17 May - 18 May
Holiday Inn Express & Suites Edwardsville by IHG

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
29.2 km from Midtown
8.0 out of 10, Very good, (1,005 reviews)
"The room was excellent"
United States
willie
The price is ฿2,191
฿2,432 total
includes taxes & fees
14 May - 15 May
Super 8 by Wyndham Troy IL/St. Louis Area

Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
16.7 km from Midtown
9.2 out of 10, Wonderful, (1,223 reviews)
"Friendly staff, great breakfast, clean room."
United States
Phil
The price is ฿3,737
฿4,385 total
includes taxes & fees
31 May - 1 Jun
Drury Inn & Suites St. Louis Airport

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
3.0 star property
17.2 km from Midtown
9.2 out of 10, Wonderful, (1,601 reviews)
"Parking was convenient and felt safe, the staff was able to accommodate an earlier check in, and the room was pretty clean overall."
United States
Hector
The price is ฿3,544
฿4,173 total
includes taxes & fees
14 May - 15 May
Wingate by Wyndham St. Louis Airport

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
24.2 km from Midtown
8.4 out of 10, Very good, (843 reviews)
"Very friendly staff, comfortable room and convenient location "
United States
Aimee
The price is ฿3,396
฿3,905 total
includes taxes & fees
25 May - 26 May
Comfort Inn Edwardsville - St. Louis

The Principal Hotel

The Principal Hotel
3.5 star property
21.4 km from Midtown
9.8 out of 10, Exceptional, (258 reviews)
"Location is great.Beds were very comfortable."
United States
Denise
The price is ฿3,635
฿4,034 total
includes taxes & fees
10 May - 11 May
The Principal Hotel

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
11.9 km from Midtown
9.0 out of 10, Wonderful, (1,543 reviews)
"Excellent place to stay with 6 restaurants to pickf from"
United States
Dennis
The price is ฿2,513
฿3,392 total
includes taxes & fees
7 Jun - 8 Jun
River City Casino & Hotel

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
24.8 km from Midtown
9.6 out of 10, Exceptional, (1,003 reviews)
"Excellent staff Very kind and helpful"
United States
Michael
The price is ฿4,511
฿5,214 total
includes taxes & fees
21 May - 22 May
Drury Inn & Suites St. Louis Arnold

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
2.5 star property
24.8 km from Midtown
9.4 out of 10, Exceptional, (1,006 reviews)
"Friendly, helpful staff!"
United States
Melissa
The price is ฿3,053
฿3,530 total
includes taxes & fees
20 May - 21 May
Pear Tree Inn St. Louis Arnold

Hampton Inn & Suites St. Louis/South I-55

Hampton Inn & Suites St. Louis/South I-55
2.5 star property
19.8 km from Midtown
9.6 out of 10, Exceptional, (1,002 reviews)
"Staff was friendly, breakfast was delicious. I really enjoyed my stay"
United States
Jenny
The price is ฿4,081
฿4,693 total
includes taxes & fees
7 Jun - 8 Jun
Hampton Inn & Suites St. Louis/South I-55

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
29.4 km from Midtown
9.4 out of 10, Exceptional, (767 reviews)
"Great place to stay and get good sleep and an excellent breakfast."
United States
debbie
The price is ฿3,768
฿4,182 total
includes taxes & fees
26 May - 27 May
Holiday Inn Express Troy by IHG

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 3.4 km from Midtown
9.4 out of 10, Exceptional, (3,406 reviews)
"Excellent location , clean hotel , great food selection "
United States
Haydee
The price is ฿5,800
฿6,781 total
includes taxes & fees
8 May - 9 May
Drury Plaza Hotel St. Louis at the Arch

Best Western St. Louis Inn

Best Western St. Louis Inn
2.5 star property
22.7 km from Midtown
8.2 out of 10, Very good, (1,012 reviews)
"Our room was clean and staff was super friendly!"
United States
Amber
The price is ฿2,616
฿3,008 total
includes taxes & fees
18 May - 19 May
Best Western St. Louis Inn

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
23.3 km from Midtown
7.8 out of 10, Good, (1,206 reviews)
"This place is always clean and staff is always friendly. I stay here we very week for work "
United States
Steve
The price is ฿2,739
฿3,163 total
includes taxes & fees
10 May - 11 May
Wingate by Wyndham St. Louis/Fenton Route 66

Hilton St. Louis Airport

Hilton St. Louis Airport
3.5 star property
16.3 km from Midtown
7.6 out of 10, Good, (1,003 reviews)
"Great breakfast, the room was comfortable nice bed. It's an older hotel but it's nicely located close to the golf course for a college event. Ate downtown by the river at Toni's "
United States
Heidi
The price is ฿4,081
฿4,870 total
includes taxes & fees
5 Jun - 6 Jun
Hilton St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Top Midtown Hotel Reviews

Frequently asked questions

What is Midtown like?
Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on our traveller data, Residence Inn by Marriott St Louis Downtown is one of the top choices for your stay in Midtown. This hotel is a short 14-minute walk from St. Louis University, and it offers an indoor pool and in-room kitchens. Another good choice for your stay in the neighbourhood is Element St. Louis Midtown.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 35 Midtown hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.
What are the top things to see and do in Midtown?
Explore Midtown's landmarks such as Washington Avenue Historic District, Scott Joplin House State Historic Site and Samuel Cupples House and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighbourhood. Favourite places to visit in the surrounding area include St. Louis Union Station, Busch Stadium and Gateway Arch. While you're out sightseeing, .ZACK Theater and The MOTO Museum are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.

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