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Search Hotels in Middletown, San Diego

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Our top choices for Middletown hotels

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (106)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
2.8 km from Middletown
8.6 out of 10, Excellent, (1454)
"So clean, Very Nice staff, convenient location ! "
United States
Cindy
The Bristol Hotel San Diego

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
2.7 km from Middletown
8.6 out of 10, Excellent, (1065)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is ฿4,253
฿5,844 total
includes taxes & fees
24 Dec - 25 Dec
The Westin San Diego Bayview

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 3.5 km from Middletown
9.2 out of 10, Wonderful, (1951)
"Amazing stay. Absolutely perfect "
United States
Wayne
The price is ฿5,002
฿7,454 total
includes taxes & fees
24 Dec - 25 Dec
Marriott Marquis San Diego Marina

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Little Italy, 2.1 km from Middletown
9.0 out of 10, Wonderful, (104)
"It was a nice place to stay at"
United States
Eric
The price is ฿3,851
฿4,465 total
includes taxes & fees
24 Dec - 25 Dec
Courtyard by Marriott San Diego Downtown Little Italy

Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
Marina District, 3.2 km from Middletown
9.0 out of 10, Wonderful, (1546)
"Clean room, friendly staff, great property. "
United States
MIGUEL
The price is ฿5,340
฿7,333 total
includes taxes & fees
23 Dec - 24 Dec
Embassy Suites by Hilton San Diego Bay Downtown

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
2.2 km from Middletown
8.8 out of 10, Excellent, (743)
"Friendly staff and clean rooms. "
Canada
Justine
The price is ฿3,423
฿3,969 total
includes taxes & fees
24 Dec - 25 Dec
The DEXTRO Little Italy, BW Premier Collection

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay, 6.5 km from Middletown
9.0 out of 10, Wonderful, (3929)
" Nice bay view from room, super friendly staff"
United States
Toshiyuki
The price is ฿4,373
฿5,656 total
includes taxes & fees
18 Dec - 19 Dec
The Dana on Mission Bay

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 3.1 km from Middletown
9.0 out of 10, Wonderful, (1013)
"Yes everything was great I will stay there again."
United States
Sergio
The price is ฿3,744
฿4,259 total
includes taxes & fees
24 Dec - 25 Dec
Gaslamp Plaza Suites

The Wayfarer San Diego

The Wayfarer San Diego
4.0 star property
Mission Beach, 9.3 km from Middletown
9.4 out of 10, Exceptional, (1709)
"Nice rooms, great location!! Staff was very friendly "
United States
Kevin M
The price is ฿6,583
฿7,567 total
includes taxes & fees
21 Dec - 22 Dec
The Wayfarer San Diego

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
2.3 km from Middletown
8.4 out of 10, Very good, (6030)
"Always an amazing stay"
United States
Jana
The price is ฿4,252
฿5,842 total
includes taxes & fees
21 Dec - 22 Dec
Wyndham San Diego Bayside

The Sofia Hotel

The Sofia Hotel
3.5 star property
2.9 km from Middletown
8.4 out of 10, Very good, (1654)
"Great location and history to the hotel "
United States
Stephanie
The Sofia Hotel

Inn By The Sea La Jolla

Inn By The Sea La Jolla
3.5 star property
15.1 km from Middletown
9.4 out of 10, Exceptional, (1739)
"Delightful stay. Perfect location. "
United States
Nicole
The price is ฿4,728
฿5,435 total
includes taxes & fees
21 Dec - 22 Dec
Inn By The Sea La Jolla

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 3.6 km from Middletown
9.4 out of 10, Exceptional, (1000)
"Great location "
United States
Mohammad
The price is ฿2,803
฿4,159 total
includes taxes & fees
4 Jan - 5 Jan 2026
Staypineapple, Hotel Z, Gaslamp San Diego

PB Surf Beachside Inn

PB Surf Beachside Inn
2.5 star property
North Pacific Beach, 10.2 km from Middletown
8.2 out of 10, Very good, (1000)
"Great stay"
United States
Ernest
The price is ฿2,860
฿3,230 total
includes taxes & fees
18 Dec - 19 Dec
PB Surf Beachside Inn

Del Mar Beach Hotel

Del Mar Beach Hotel
2.0 star property
26.3 km from Middletown
9.4 out of 10, Exceptional, (1004)
"Room was great, staff was great!"
United States
Jude
Del Mar Beach Hotel

Pacific View Inn

Pacific View Inn
2.0 star property
North Pacific Beach, 10.1 km from Middletown
7.8 out of 10, Good, (1003)
"Wonderful location, clean rooms. "
United States
Maureen
The price is ฿3,215
฿3,631 total
includes taxes & fees
21 Dec - 22 Dec
Pacific View Inn

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 3.4 km from Middletown
9.0 out of 10, Wonderful, (2870)
"Great Location....tons of walking from the hotel Front desk were very nice and polite will be coming back for sure "
United States
Carlos
The price is ฿5,537
฿8,134 total
includes taxes & fees
18 Dec - 19 Dec
Manchester Grand Hyatt San Diego

La Pensione Hotel

La Pensione Hotel
3.0 star property
Little Italy, 2 km from Middletown
8.6 out of 10, Excellent, (1912)
"Great check-in experience, convenient parking, the room was clean and bed was comfortable. The city view option was exceptionally pleasant. Will stay again! "
United States
Mike
La Pensione Hotel

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
2.2 km from Middletown
9.2 out of 10, Wonderful, (2953)
"Friendly, staff was very helpful, great size rooms, and over all was an amazing stay"
United States
Naya
The price is ฿4,787
฿5,502 total
includes taxes & fees
21 Dec - 22 Dec
Legacy Resort Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Middletown

Find the best Middletown areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Middletown Hotel Reviews

Frequently asked questions

What's it like in Middletown?
Middletown is a neighbourhood that travellers like for its live music, bars and theatres.
How many hotels can I expect to find in the Middletown area?
Expedia has 91 hotels and other accommodation options in Middletown to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Middletown, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to view top deals in Middletown.
What are the top things to see and do in Middletown?
Favourite places to visit in the surrounding area include San Diego Zoo, Hotel Circle and Port of San Diego. While you're out sightseeing, Petco Park and Marston House are a couple of additional sights to visit in San Diego.
How can I get around Middletown and the greater San Diego area?
Ready to get out and explore the city? Middletown Station is the closest metro station.