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Check prices for these dates

Tonight
26 Aug - 27 Aug
Tomorrow
27 Aug - 28 Aug
This weekend
29 Aug - 31 Aug
Next weekend
5 Sep - 7 Sep

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Top 10 Mesopotamia hotels and places to stay

To Spiti tis Sofias
Interior

To Spiti tis Sofias

10.0 out of 10, Exceptional, (1)
"Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin. "
The price is ฿2,167
฿2,537 total
includes taxes & fees
8 Sept - 9 Sept
To Spiti tis Sofias
Limneon Resort & Spa
3 restaurants, breakfast, lunch, dinner served; Greek cuisine

Limneon Resort & Spa

4.0 star property
9.2 out of 10, Wonderful, (189)
"Wonderful stay. "
The price is ฿3,160
฿3,968 total
includes taxes & fees
4 Sept - 5 Sept
Limneon Resort & Spa
Chloe Hotel
Free daily buffet breakfast

Chloe Hotel

3.0 star property
10.0 out of 10, Exceptional, (84)
"We enjoyed the stay, friendly staff and nice breakfast "
The price is ฿3,324
฿3,964 total
includes taxes & fees
26 Sept - 27 Sept
Chloe Hotel
Esperos Palace Luxury & Spa Hotel
Breakfast, lunch and dinner served

Esperos Palace Luxury & Spa Hotel

4.0 star property
9.0 out of 10, Wonderful, (83)
"Gorgeous and spacious. Very classy and modern. I've stayed here twice and will definitely go back. "
The price is ฿3,494
฿4,348 total
includes taxes & fees
27 Aug - 28 Aug
Esperos Palace Luxury & Spa Hotel
Calma Hotel & Spa
Property grounds

Calma Hotel & Spa

4.0 star property
9.6 out of 10, Exceptional, (34)
"Great place to relax. Very kind staff all over. Nice breakfast buffet."
Calma Hotel & Spa
Hotel Anastassiou
Front of property – evening/night

Hotel Anastassiou

2.0 star property
8.0 out of 10, Very good, (67)
"Nice hotel. Nice room. Nice people!! Not walkable to town but a very short drive! And a very lovable property pup!! Thank you for your hospitality!! "
The price is ฿1,662
฿1,963 total
includes taxes & fees
26 Sept - 27 Sept
Hotel Anastassiou
Orologopoulos Mansion
Deluxe Double or Twin Room | Minibar, in-room safe, soundproofing, iron/ironing board

Orologopoulos Mansion

5.0 star property
9.6 out of 10, Exceptional, (33)
"Wonderful Boutique hotel in center of old town"
Orologopoulos Mansion
Kyknos De Luxe Hotel
Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds

Kyknos De Luxe Hotel

10.0 out of 10, Exceptional, (42)
"Very nice clean, very polite staff and great breakfast!"
The price is ฿2,842
฿3,418 total
includes taxes & fees
27 Aug - 28 Aug
Kyknos De Luxe Hotel
Guesthouse Vissinokipos
Garden

Guesthouse Vissinokipos

9.4 out of 10, Exceptional, (10)
"Wonderfull view and very friendly people.the place is avery dpecial artistic decorated.wonderfull weather.nice varieties for breakfast.price was ver good.i recommend it!"
Guesthouse Vissinokipos
Arhontiko Christodoulou
Exterior

Arhontiko Christodoulou

2.0 star property
Arhontiko Christodoulou
Guest House Ilektra
Exterior

Guest House Ilektra

9.8 out of 10, Exceptional, (6)
"A fantastic experience. Don't hesitate to stop at Ilektra Guest House. People are delicious, the diner was perfect with a lot of mushrooms they got in the mountains during the day. A fabulous place !!! Thanks again to our guests"
The price is ฿1,662
฿1,963 total
includes taxes & fees
27 Aug - 28 Aug
Guest House Ilektra
Anesis Hotel
Property grounds

Anesis Hotel

2.0 star property
9.0 out of 10, Wonderful, (9)
"Fantastic hotel in the heart of Kastoria. The owners are lovely people, very helpful and made me feel right at home. Will definitely stay there again!"
The price is ฿1,839
฿2,165 total
includes taxes & fees
27 Aug - 28 Aug
Anesis Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Mesopotamia

Venture to Kastoria Lake and Dragon's Lair—just two of the sights around Mesopotamia.

See all hotels in Mesopotamia

Top Mesopotamia Hotel Reviews

More cheap stays in Mesopotamia

More cheap stays in Mesopotamia

Hotel Anastassiou

Hotel Anastassiou

1st km Highway Kastoria-Athens, Kastoria, Western Macedonia
The price is ฿1,662 per night from 26 Sept to 27 Sept
฿1,662
฿1,963 total
26 Sept - 27 Sept
includes taxes & fees
8/10 Very Good! (67 reviews)

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Where is the best place for a stay in Mesopotamia?

To Spiti tis Sofias is one of the top choices for your stay based on our traveller data. This guest house offers free parking and free WiFi. Two other choices for your stay in the area are Limneon Resort & Spa and Hotel Anastassiou. See all available top hotels, or vacation rentals in Mesopotamia.

If I need to cancel my hotel reservation in Mesopotamia, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesopotamia.

What is staying in Mesopotamia like?

Travellers to Mesopotamia will find plenty to explore and enjoy. There are 44 hotels and other accommodation options in the surrounding area. Find out more about Mesopotamia.

What are the top places to visit in Mesopotamia?

Places to visit in the wider area include Kastoria Lake, Dragon's Lair and Holy Monastery of Panagias Mauriotissas. You'll also find Folklore Museum of Kastoria and Holy Prophet Elias Church in the area. Take a look at what more there is to see and do in Expedia's Mesopotamia guide.

What's the seasonal weather like in Mesopotamia?

The hottest months are usually August and July, with an average temperature of 20°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Mesopotamia is 707 mm.