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Top 10 Mesilla hotels and places to stay

Our top choices for Mesilla hotels

Comfort Inn & Suites Las Cruces Mesilla

2.5 star property
9.0 out of 10, Wonderful, (1005)
"Great place Al the way around. "
The price is ฿3,346
฿3,875 total
includes taxes & fees
7 Sept - 8 Sept
Comfort Inn & Suites Las Cruces Mesilla

Best Western Mission Inn

2.5 star property
8.8 out of 10, Excellent, (1214)
"Best hotel"
The price is ฿2,470
฿2,873 total
includes taxes & fees
8 Sept - 9 Sept
Best Western Mission Inn

Hotel Encanto de Las Cruces

3.5 star property
9.0 out of 10, Wonderful, (1462)
"Great stay!"
The price is ฿3,590
฿5,026 total
includes taxes & fees
1 Sept - 2 Sept
Hotel Encanto de Las Cruces

Home2 Suites by Hilton Las Cruces

3.0 star property
9.4 out of 10, Exceptional, (625)
"Beautiful hotel, loved it! "
The price is ฿4,370
฿5,035 total
includes taxes & fees
1 Sept - 2 Sept
Home2 Suites by Hilton Las Cruces

Comfort Suites Las Cruces I-25 North

2.5 star property
9.2 out of 10, Wonderful, (1002)
"We love staying at the hotel the staff are very friendly and the rooms are amazing "
The price is ฿3,540
฿4,213 total
includes taxes & fees
8 Sept - 9 Sept
Comfort Suites Las Cruces I-25 North

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

3.0 star property
8.2 out of 10, Very good, (2230)
"great stay"
The price is ฿1,917
฿2,255 total
includes taxes & fees
8 Sept - 9 Sept
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

Springhill Suites By Marriott Las Cruces

3.0 star property
8.6 out of 10, Excellent, (909)
"Great location, continental breakfast was awesome and the price couldn’t be beat! "
The price is ฿2,712
฿3,155 total
includes taxes & fees
14 Sept - 15 Sept
Springhill Suites By Marriott Las Cruces

Holiday Inn Express & Suites Las Cruces North by IHG

2.5 star property
9.0 out of 10, Wonderful, (952)
"Clean, friendly staff, good breakfast "
The price is ฿3,712
฿4,290 total
includes taxes & fees
1 Sept - 2 Sept
Holiday Inn Express & Suites Las Cruces North by IHG

Hampton Inn & Suites Las Cruces I-10

2.5 star property
8.8 out of 10, Excellent, (1006)
"Great hotel"
The price is ฿3,415
฿3,953 total
includes taxes & fees
14 Sept - 15 Sept
Hampton Inn & Suites Las Cruces I-10

Days Inn by Wyndham Las Cruces

2.5 star property
8.2 out of 10, Very good, (1203)
"Clean and great location for nigjt stay on road trip"
The price is ฿1,564
฿1,854 total
includes taxes & fees
8 Sept - 9 Sept
Days Inn by Wyndham Las Cruces

Courtyard by Marriott Las Cruces at NMSU

3.0 star property
9.4 out of 10, Exceptional, (482)
"Thanks for a great stay "
The price is ฿4,778
฿5,498 total
includes taxes & fees
28 Sept - 29 Sept
Courtyard by Marriott Las Cruces at NMSU

Drury Inn & Suites Las Cruces

3.0 star property
9.4 out of 10, Exceptional, (1005)
"Nice hotel, will definitely stay there again "
The price is ฿3,298
฿3,820 total
includes taxes & fees
7 Sept - 8 Sept
Drury Inn & Suites Las Cruces

Hilton Garden Inn Las Cruces

3.0 star property
9.0 out of 10, Wonderful, (1004)
"Good location, friendly staff "
The price is ฿3,914
฿4,519 total
includes taxes & fees
1 Sept - 2 Sept
Hilton Garden Inn Las Cruces

Super 8 by Wyndham Las Cruces/White Sands Area

2.0 star property
7.2 out of 10, Good, (1006)
"It was excellent in everything."
The price is ฿1,702
฿2,010 total
includes taxes & fees
8 Sept - 9 Sept
Super 8 by Wyndham Las Cruces/White Sands Area

Hampton Inn & Suites Las Cruces I-25

2.5 star property
8.6 out of 10, Excellent, (1007)
"Good place to stay we where there for one night overall good."
The price is ฿3,304
฿3,827 total
includes taxes & fees
14 Sept - 15 Sept
Hampton Inn & Suites Las Cruces I-25

Studio 6 – Las Cruces, NM - Telshor

2.0 star property
7.0 out of 10, Good, (97)
"Overall good place to stay!"
The price is ฿2,227
฿2,606 total
includes taxes & fees
12 Sept - 13 Sept
Studio 6 – Las Cruces, NM - Telshor

Staybridge Suites Las Cruces by IHG

3.0 star property
8.8 out of 10, Excellent, (1001)
"Very nice clean place to stay. Had everything we needed!!"
The price is ฿4,326
฿4,986 total
includes taxes & fees
1 Sept - 2 Sept
Staybridge Suites Las Cruces by IHG

Century 21 Motel

2.0 star property
6.8 out of 10, (161)
"Friendly staff"
The price is ฿2,005
฿2,559 total
includes taxes & fees
31 Aug - 1 Sept
Century 21 Motel

Econo Lodge Las Cruces University Area

2.0 star property
7.2 out of 10, Good, (637)
"Overall the hotel was friendly and helpful, bed wasn't comfortable at all,room was clean and shower hot water needs to get hotter.."
The price is ฿1,704
฿2,121 total
includes taxes & fees
29 Sept - 30 Sept
Econo Lodge Las Cruces University Area

Sleep Inn University

2.5 star property
7.6 out of 10, Good, (1007)
"Very quiet abd ztaff very friendly "
The price is ฿2,005
฿2,347 total
includes taxes & fees
10 Sept - 11 Sept
Sleep Inn University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Mesilla

Historic adobe buildings surround the plaza where Billy the Kid once stood trial in this charming town. Explore local art galleries and sample authentic Mexican cuisine at La Posta, a restaurant housed in a 19th-century stagecoach stop.

Photo by Lane
Open Photo by Lane

Top Mesilla Hotel Reviews

Frequently asked questions

What's the best place for a stay in Mesilla?

Located 4.5 mi (7.3 km) from the heart of Mesilla, Hotel Encanto de Las Cruces is a top choice for your stay, based on our traveller data. Other good choices for your visit to the area are La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces. See all available top hotels, or vacation rentals in Mesilla.

If I need to cancel my hotel reservation in Mesilla, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesilla.

What are some hotels with pools in Mesilla?

Hotel Encanto de Las Cruces: Hotel located near New Mexico State University. Provides 3 bars, an outdoor pool and a 24-hour fitness centre. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces are two additional hotels that offer an on-site pool. View all hotels with pools in Mesilla.

What is staying in Mesilla like?

Visitors can enjoy all that Mesilla has to offer, including the restaurants, shopping and theatres. In Mesilla, there are 15 hotels and other accommodation options to choose from. Find out more about Mesilla.

What should I do while I'm visiting Mesilla?

Cultural venues include Fountain Theatre and Fountain Theater. Landmarks like Mesillia Plaza and San Albino Basilica might be worth a visit. Additionally, you might want to add Rio Grande to your itinerary. Take a look at what more there is to see and do in Expedia's Mesilla guide.

What's the seasonal weather in Mesilla?

The hottest months are usually June and July, with an average temperature of 28°C, while the coldest months are January and December, with an average of 9°C. Average annual precipitation for Mesilla is 227 mm.