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Our top choices for Medical University of South Carolina hotels

2 Charles | Living area | 42-inch Smart TV with digital channels, TV, Netflix
Beautiful Renovated Apartment Near King Street

Beautiful Renovated Apartment Near King Street

Beautiful Renovated Apartment Near King Street
3.5 star property
Cannonborough Elliotborough, 0.7 km from Medical University of South Carolina
10.0 out of 10, Exceptional, (5)
"Very clean, bright. Very comfortable bed, nice shower and amenities. Also convenient to our venue - within walking distance to our activities."
United States
Anonymous traveller
The price is ฿7,444
฿18,904 total
includes taxes & fees
4 Jan - 5 Jan 2026
Beautiful Renovated Apartment Near King Street
Terrace/patio
The Nickel Hotel

The Nickel Hotel

The Nickel Hotel
4.0 star property
King Street, 0.8 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (82)
"Beautiful hotel!! Close to shopping and dining! Highly recommended!!"
United States
Matthew
The price is ฿7,010
฿8,059 total
includes taxes & fees
5 Jan - 6 Jan 2026
The Nickel Hotel
Premier Suite, Ground Floor | 1 bedroom, premium bedding, down duvets, memory-foam beds
The Iris Charleston

The Iris Charleston

The Iris Charleston
3.0 star property
Cannonborough Elliotborough, 0.9 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (123)
"Clean room and well located"
United States
Stephen
The price is ฿4,209
฿6,946 total
includes taxes & fees
6 Jan - 7 Jan 2026
The Iris Charleston
Traditional Apartment | Private kitchen | Full-sized fridge, microwave, oven, stovetop
The Palmetto House

The Palmetto House

The Palmetto House
2.5 star property
Cannonborough Elliotborough, 0.5 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (15)
"Wonderful experience. Apartment was very nice & in a great location! Highly recommend!"
United States
Jennifer
The price is ฿5,277
฿12,297 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Palmetto House
Lounge
The Loutrel

The Loutrel

The Loutrel
4.0 star property
French Quarter, 1.9 km from Medical University of South Carolina
10.0 out of 10, Exceptional, (1001)
"Beautiful hotel in a great location "
United States
Sean
The Loutrel
Reception
The Pinch Hotel

The Pinch Hotel

The Pinch Hotel
4.0 star property
King Street, 1.2 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (172)
"Wonderful stay at The Pinch! The staff is lovely, friendly and helpful. They were able to offer us an upgrade, and the accommodations are well-designed with high-end finishes. Absolutely recommend! "
United States
Heather
The Pinch Hotel
Room, 1 King Bed | Premium bedding, down duvets, memory-foam beds, individually decorated
Luxurious Private Suites in Downtown Charleston

Luxurious Private Suites in Downtown Charleston

Luxurious Private Suites in Downtown Charleston
3.0 star property
Cannonborough Elliotborough, 0.6 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (70)
"Property was very clean and had all the amenities of a hotel but a lot more room. Bed was very comfortable as well which is a rarity in my opinion. Great walking options for dining. Host was excellent with anything we needed! Did not use the pool so cannot comment."
United States
Helen
The price is ฿5,088
฿8,486 total
includes taxes & fees
28 Dec - 29 Dec
Luxurious Private Suites in Downtown Charleston
Courtyard
Hilton Club Liberty Place Charleston

Hilton Club Liberty Place Charleston

Hilton Club Liberty Place Charleston
3.5 star property
Ansonborough, 1.6 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (889)
"Wonderful two bedroom suite and room was cleaned daily - wonderful location as well."
United States
Liz
The price is ฿6,675
฿7,609 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Club Liberty Place Charleston
Anson Suite | Frette Italian sheets, premium bedding, Tempur-Pedic beds, in-room safe
Zero George Street

Zero George Street

Zero George Street
5.0 star property
Ansonborough, 1.6 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (354)
"A delightful stay in a delightful setting. "
United States
Tommy
The price is ฿8,452
฿9,778 total
includes taxes & fees
5 Jan - 6 Jan 2026
Zero George Street
Terrace/patio
French Quarter Inn

French Quarter Inn

French Quarter Inn
4.0 star property
French Quarter, 1.8 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (1004)
"Phenomenal stay - highly recommend"
United States
Patricia
French Quarter Inn
Apartment | Laptop workspace, iron/ironing board, free WiFi, bed sheets
Perfect Location in Downtown Charleston

Perfect Location in Downtown Charleston

Perfect Location in Downtown Charleston
3.5 star property
Cannonborough Elliotborough, 0.7 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (16)
"This was the cutest place and it had everything we needed! The location was amazing!! 10/10, we’re already talking about coming back! "
United States
Alexandra
The price is ฿5,088
฿17,968 total
includes taxes & fees
5 Jan - 6 Jan 2026
Perfect Location in Downtown Charleston
Front of property
The Spectator Hotel

The Spectator Hotel

The Spectator Hotel
4.0 star property
French Quarter, 1.9 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (986)
"Excellent 5 star hotel"
United States
John
The Spectator Hotel
Outdoor pool, pool cabanas (surcharge), pool umbrellas
Hotel Bennett

Hotel Bennett

Hotel Bennett
5.0 star property
King Street, 1 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (980)
"Absolutely loved the stay. We’ve stayed a few other times in the past and it never disappoints! If you want a luxury hotel right on King street you can’t do better! We will continue to come back. "
United States
Donald
The price is ฿12,218
฿14,000 total
includes taxes & fees
23 Dec - 24 Dec
Hotel Bennett
Restaurant
The Restoration

The Restoration

The Restoration
4.0 star property
King Street, 1.3 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (1007)
"Great place to stay for a few nights while visiting!"
United States
Kelly
The price is ฿7,406
฿8,703 total
includes taxes & fees
8 Jan - 9 Jan 2026
The Restoration
Lounge
HarbourView Inn

HarbourView Inn

HarbourView Inn
4.0 star property
French Quarter, 2.1 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (1003)
"Clean and spacious room, excellent staff and "treats," and great location - can walk to almost everything."
United States
Nancy
HarbourView Inn
Restaurant
Andrew Pinckney Inn

Andrew Pinckney Inn

Andrew Pinckney Inn
4.0 star property
Ansonborough, 1.7 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (1444)
"Our room at the Andrew Pinckney Inn was impeccably clean. Their breakfast is always enjoyable and being situated in the solarium with a view is great."
United States
Kristopher
Andrew Pinckney Inn
Free daily on-the-go breakfast
The Nicholas

The Nicholas

The Nicholas
3.0 star property
Harleston Village, 1 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (32)
"Really enjoyed my stay. Good plunge pool, very walkable & easy parking. Nice breakfast also included! "
United States
leslieanne
The price is ฿8,282
฿10,749 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Nicholas
Courtyard
Hotel Richemont

Hotel Richemont

Hotel Richemont
4.0 star property
King Street, 1.3 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (58)
"Loved the staff, very kind and helpful.. love the hotel rooms. Area very walkable and safe. Loved the French Bakery across the street. We will be back. "
United States
JANET
The price is ฿8,135
฿9,274 total
includes taxes & fees
23 Dec - 24 Dec
Hotel Richemont
Lobby
The Charleston Place

The Charleston Place

The Charleston Place
5.0 star property
Charleston Historic District, 1.5 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (1004)
"Staff was great, room perfect and we had a lovely time in Charleston!😊"
United States
Janis
The Charleston Place
Free daily self-service breakfast
Indigo Inn

Indigo Inn

Indigo Inn
3.0 star property
Ansonborough, 1.5 km from Medical University of South Carolina
9.4 out of 10, Exceptional, (1005)
"Everything was clean and staff so friendly. "
United States
Tracey
Indigo Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Medical University of South Carolina Hotel Reviews

Planters Inn

Planters Inn

10/10 Excellent
"Staff was great, rooms were clean but a little outdated."
DANA 2-night trip
Posted 4 days ago
Planters Inn

Hotels near other Medical University of South Carolina attractions

Waring Historical Library

Learn about the local history of Charleston with a stop at Waring Historical Library. Discover the lively bars and acclaimed art galleries in this walkable area.
See properties

Macaulay Museum of Dental History

You can browse the exhibits at Macaulay Museum of Dental History, a museum with a storied past, during your travels to Charleston. Stroll along the area's beautiful beaches or simply savour its top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Medical University of South Carolina?
Medical University of South Carolina is located in a historic area of Charleston known for its array of dining options and stunning churches. If you're looking for a convenient place to stay, take a look at the 1157 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to Medical University of South Carolina?
Adjacent to Medical University of South Carolina, The Ashley is one of the top choices for your stay based on our traveller data, and this B&B offers free breakfast and free parking. Other good choices close by include The Francis Marion Hotel and Hyatt Place Charleston/Historic District.
How many hotels should I expect to find near Medical University of South Carolina?
Expedia has 1157 hotels and other accommodation options within a mile from Medical University of South Carolina.
If I need to cancel the hotel reservation for my stay near Medical University of South Carolina, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review the best options available near Medical University of South Carolina.
What can I see and do near Medical University of South Carolina?
Study the collections at Charleston Museum, Aiken-Rhett House Museum or Gibbes Museum of Art. Sights like Charleston Music Hall, Charleston City Market and Dock Street Theater are landmarks to visit in the area. You can catch a show at Music Farm, Charleston Gaillard Center and American Theater.