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Top Trending Hotels Near Mayo Clinic Florida

Breakfast, lunch, dinner served; American cuisine
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (23)
"Great staff and rooms "
United States
Albert
The price is ฿3,860
฿4,381 total
includes taxes & fees
21 Dec - 22 Dec
Hilton Jacksonville At Mayo Clinic
Reception
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (440)
"Great facility to stay."
United States
Gary
The price is ฿4,825
฿5,476 total
includes taxes & fees
25 Nov - 26 Nov
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Terrace/patio
TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East

3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (540)
"Very good hotel"
United States
Careli
The price is ฿3,692
฿4,190 total
includes taxes & fees
25 Nov - 26 Nov
TownePlace Suites by Marriott Jacksonville East
Terrace/patio
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1003)
"Spacious clean room, very quiet during our stay, friendly, helpful staff and breakfast was great."
United States
Joy
The price is ฿3,471
฿3,940 total
includes taxes & fees
30 Nov - 1 Dec
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 star property
2.7 km from Mayo Clinic Florida
8.6 out of 10, Excellent, (1005)
"We enjoyed the stay."
United States
Kenny
The price is ฿3,530
฿4,006 total
includes taxes & fees
29 Nov - 30 Nov
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Terrace/patio
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

3.0 star property
0.3 km from Mayo Clinic Florida
8.4 out of 10, Very good, (750)
"Nice hotel, close to shops and mayo clinic."
United States
Judy
The price is ฿5,214
฿5,917 total
includes taxes & fees
28 Nov - 29 Nov
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
BBQ/picnic Area
Salt Air Inn & Suites

Salt Air Inn & Suites

2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (395)
"A cute little gem with some of the best hospitality in the area. "
United States
Windy
Salt Air Inn & Suites
Lobby
Element Jacksonville Beach

Element Jacksonville Beach

3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (512)
"Clean room and friendly staff."
United States
Lucia
The price is ฿4,113
฿4,668 total
includes taxes & fees
21 Dec - 22 Dec
Element Jacksonville Beach
Exterior
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

2.5 star property
Southside, 7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1007)
"Nice staff nice room"
United States
Thomas
The price is ฿4,242
฿4,815 total
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Property amenity
TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport

3.0 star property
10.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (53)
"This was an awesome place to stay."
United States
Christine
The price is ฿3,765
฿4,273 total
includes taxes & fees
21 Dec - 22 Dec
TownePlace Suites by Marriott® Jacksonville Mayport
Standard Room, 2 Queen Beds, Non Smoking | 1 bedroom, down duvets, minibar, iron/ironing board
The Hotel Palms

The Hotel Palms

3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (291)
"stayed here for an event and it was awesome"
United States
clayton
The price is ฿6,120
฿6,947 total
includes taxes & fees
1 Dec - 2 Dec
The Hotel Palms
2 outdoor pools, open 7:00 AM to 9:00 PM, pool umbrellas, pool loungers
Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2560)
"Very nice oceanfront hotel with a friendly staff and really good breakfast."
United States
Kawanda
The price is ฿4,326
฿4,910 total
includes taxes & fees
25 Nov - 26 Nov
Hampton Inn Jacksonville Beach/Oceanfront
Reception
Ponte Vedra Inn & Club

Ponte Vedra Inn & Club

5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (811)
"Wonderful place to visit to relax. Very clean, very friendly and courteous staff. Great view from the balcony."
United States
Greg
The price is ฿12,920
฿15,345 total
includes taxes & fees
30 Nov - 1 Dec
Ponte Vedra Inn & Club
On the beach, white sand, surfing, kayaking
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3367)
"I had a great weekend stay on my birthday! "
United States
Adrian
Margaritaville Jacksonville Beach
Beach/ocean view
The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach

5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (684)
"Clean room, excellent service and only steps from the ocean. The facility could use some TLC but, all in all, a wonderful place to stay. We’ll be back for sure. "
United States
Robert
The price is ฿12,920
฿15,345 total
includes taxes & fees
23 Nov - 24 Nov
The Lodge and Club at Ponte Vedra Beach
On the beach
Best Western Oceanfront

Best Western Oceanfront

3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1006)
"Had a great beachfront stay"
United States
Grace
The price is ฿3,989
฿4,528 total
includes taxes & fees
25 Nov - 26 Nov
Best Western Oceanfront
Exterior
Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront

3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1000)
"Easy to walk to the beach and local restaurant"
United States
Allen D
The price is ฿5,485
฿6,226 total
includes taxes & fees
24 Nov - 25 Nov
Four Points by Sheraton Jacksonville Beachfront
On the beach, windsurfing
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (615)
"Everything was perfect! "
United States
Lindsey
The price is ฿4,922
฿5,587 total
includes taxes & fees
25 Nov - 26 Nov
Springhill Suites By Marriott Jacksonville Beach Oceanfront
Free daily buffet breakfast
Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG

3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1000)
"The check in was simple and a room was ready for us before check out time. We were able to rest and sleep well during our stay in Jacksonville Beach."
United States
David
The price is ฿3,951
฿4,484 total
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Express Jacksonville Beach by IHG
Lounge
AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center

2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (160)
"Staff was excellent...highly recommend this Hotel"
Canada
Robert
The price is ฿4,501
฿5,109 total
includes taxes & fees
25 Nov - 26 Nov
AC Hotel Jacksonville St Johns Town Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels close to Mayo Clinic Florida with free breakfast

Reception
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
  • Breakfast included
9.4 out of 10, Exceptional, (440)
The price is ฿4,825
฿5,476 total
includes taxes & fees
25 Nov - 26 Nov
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
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Top guest rated hotels close to Mayo Clinic Florida

Standard Room, 2 Queen Beds, Non Smoking | 1 bedroom, down duvets, minibar, iron/ironing board
The Hotel Palms
The Hotel Palms
3.5 star property
    9.6 out of 10, Exceptional, (291)
    The price is ฿6,120
    ฿6,947 total
    includes taxes & fees
    1 Dec - 2 Dec
    The Hotel Palms
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    Top Mayo Clinic Florida Hotel Reviews

    Hilton Jacksonville At Mayo Clinic

    Hilton Jacksonville At Mayo Clinic

    10/10 Excellent
    "I booked this hotel after seeing it on TikTok and it ended up being the perfect staycation choice. The property is new, modern, and very clean. Our room was cozy with a beautiful view of both the sunset and sunrise. The bed was incredibly comfortable, and I loved the motion-sensor lights along the sides — such a thoughtful touch for nighttime. The bathroom was spacious, and the shower was a great size. The room also had an empty mini fridge (ideal for keeping drinks chilled) and a microwave for leftovers, which made the stay even more convenient. The gym was well-equipped with quality workout machines, much better than the typical hotel gym setup. I didn’t get a chance to check out the pool this time, but I definitely plan to when I return. Overall, this Hilton exceeded my expectations. Stylish, quiet, and comfortable — I’d absolutely stay here again."
    Renee 1-night trip
    Posted 2 days ago
    Hilton Jacksonville At Mayo Clinic

    Hotels near other Mayo Clinic Florida attractions

    Adventure Landing

    4.1/5 (157 reviews)
    This amusement park east of Jacksonville is a fun daytrip for the whole family with thrilling rides, exciting attractions for kids and a shipwreck-themed waterpark.
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    Windsor Parke Golf Club

    Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event.
    See properties

    Frequently asked questions

    What's the area like around Mayo Clinic Florida?
    Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 41 hotels and other accommodation options you'll find within a mile.
    Where is the best place to stay close to Mayo Clinic Florida?
    Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
    How many hotels are there near Mayo Clinic Florida?
    Expedia has 41 hotels and other accommodation options within a mile from Mayo Clinic Florida.
    If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
    Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
    What can I see and do near Mayo Clinic Florida?
    You can enjoy live performances at Players by the Sea and Wilson Center For the Arts. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Gonzales Park. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.