Photo by Caroline Nunez

Find hotels in Mayesville, SC from ฿1,912

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Check prices for these dates

Tonight
24 Dec - 25 Dec
Tomorrow
25 Dec - 26 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Mayesville hotels

BBQ/picnic Area
SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
2.5 star property
Manning
8.6 out of 10, Excellent, (1001)
"Easy check in and out. Friendly staff, quiet and cozy. Breakfast is average but plenty to choose from. "
United States
Monica
The price is ฿2,644
฿2,935 total
includes taxes & fees
1 Jan - 2 Jan 2026
SureStay Hotel by Best Western Manning
Interior entrance
Hampton Inn Manning

Hampton Inn Manning

Hampton Inn Manning
2.5 star property
Manning
8.4 out of 10, Very good, (1000)
"Staff is always super friendly!"
United States
Kirk
The price is ฿3,712
฿4,120 total
includes taxes & fees
24 Jan - 25 Jan 2026
Hampton Inn Manning
Garden
1912 Bed and Breakfast

1912 Bed and Breakfast

1912 Bed and Breakfast
3.5 star property
Sumter
10.0 out of 10, Exceptional, (284)
"Good "
United States
Ronald
The price is ฿3,647
฿4,114 total
includes taxes & fees
5 Jan - 6 Jan 2026
1912 Bed and Breakfast
Desk, iron/ironing board, free cots/infant beds, free WiFi
Holiday Inn Express Sumter by IHG

Holiday Inn Express Sumter by IHG

Holiday Inn Express Sumter by IHG
2.5 star property
Sumter
8.8 out of 10, Excellent, (699)
"My room was spotless. The staff was friendly and the breakfast was awesome. I will definitely be staying at the Holiday Inn Express during my travels. "
United States
Kay
The price is ฿3,048
฿3,414 total
includes taxes & fees
18 Jan - 19 Jan 2026
Holiday Inn Express Sumter by IHG
Exterior
Woodspring Suites Sumter Near Shaw Afb

Woodspring Suites Sumter Near Shaw Afb

Woodspring Suites Sumter Near Shaw Afb
2.5 star property
Sumter
8.2 out of 10, Very good, (141)
"The staff was very friendly and the rooms were clean. "
United States
Kevin
The price is ฿3,235
฿3,623 total
includes taxes & fees
26 Dec - 27 Dec
Woodspring Suites Sumter Near Shaw Afb
Lobby
Tru by Hilton Sumter

Tru by Hilton Sumter

Tru by Hilton Sumter
2.5 star property
Sumter
8.8 out of 10, Excellent, (671)
"Very clean room Will stay here in the future "
United States
michael
The price is ฿2,653
฿2,971 total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru by Hilton Sumter
Exterior
Best Inn of Manning

Best Inn of Manning

Best Inn of Manning
2.5 star property
Manning
8.0 out of 10, Very good, (9)
"Clean, comfortable, and efficient stay with friendly helpful staff and great value for your money."
United States
Loren
The price is ฿2,279
฿2,529 total
includes taxes & fees
1 Jan - 2 Jan 2026
Best Inn of Manning
Lobby
Hyatt Place Sumter / Downtown

Hyatt Place Sumter / Downtown

Hyatt Place Sumter / Downtown
3.0 star property
Sumter
9.2 out of 10, Wonderful, (881)
"Great space good breakfast and spacious rooms clean and comfortable "
United States
Savia
The price is ฿3,577
฿4,006 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hyatt Place Sumter / Downtown
Lobby
Super 8 by Wyndham Manning

Super 8 by Wyndham Manning

Super 8 by Wyndham Manning
2.0 star property
Manning
6.4 out of 10, (374)
"Clean, nice breakfast "
United States
Tanya
The price is ฿1,851
฿2,055 total
includes taxes & fees
4 Jan - 5 Jan 2026
Super 8 by Wyndham Manning
Room, 2 Queen Beds | Individually decorated, individually furnished, desk, free WiFi
Spark by Hilton Sumter

Spark by Hilton Sumter

Spark by Hilton Sumter
2.5 star property
Sumter
7.6 out of 10, Good, (15)
"Really enjoyed my stay. Room was clean and spacious. Jessica was very accommodating, professional and made our stay enjoyable."
United States
Cassandra
The price is ฿3,290
฿3,685 total
includes taxes & fees
30 Dec - 31 Dec
Spark by Hilton Sumter
Lobby sitting area
Baymont by Wyndham Manning

Baymont by Wyndham Manning

Baymont by Wyndham Manning
2.5 star property
Manning
6.8 out of 10, (1000)
"Easy access to highway and plenty of parking"
United States
Jim
The price is ฿2,488
฿2,762 total
includes taxes & fees
28 Dec - 29 Dec
Baymont by Wyndham Manning
Two double beds non smoking | View from room
Hampton Inn Sumter

Hampton Inn Sumter

Hampton Inn Sumter
2.5 star property
Sumter
8.6 out of 10, Excellent, (488)
"Truly enjoy staying here, the staff is extremely friendly and understanding! It is very clean and comfortable! "
United States
Stefanie
The price is ฿2,780
฿3,207 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Sumter
Desk, iron/ironing board, free WiFi, bed sheets
Budget Inn Timmonsville

Budget Inn Timmonsville

Budget Inn Timmonsville
2.0 star property
Timmonsville
7.0 out of 10, Good, (321)
"Very nice, always clean and easy on off access from route 95."
United States
Debbie
The price is ฿1,707
฿1,912 total
includes taxes & fees
28 Dec - 29 Dec
Budget Inn Timmonsville
Free daily continental breakfast
Comfort Suites Sumter near Shaw AFB

Comfort Suites Sumter near Shaw AFB

Comfort Suites Sumter near Shaw AFB
2.5 star property
Sumter
7.2 out of 10, Good, (600)
"Very nice rooms"
United States
Seth
The price is ฿3,125
฿3,500 total
includes taxes & fees
1 Jan - 2 Jan 2026
Comfort Suites Sumter near Shaw AFB
Room, 2 Double Beds | Desk, blackout curtains, iron/ironing board, rollaway beds
Americas Best Value Inn Bishopville

Americas Best Value Inn Bishopville

Americas Best Value Inn Bishopville
2.0 star property
Bishopville
7.2 out of 10, Good, (90)
"The room smelled clean, looked clean and I found no bed bugs. To look at it, we were not sure about our choice. But the wife and I were very pleased. If in the area, we will definitely stay there again. "
United States
Charles
The price is ฿2,644
฿2,961 total
includes taxes & fees
26 Dec - 27 Dec
Americas Best Value Inn Bishopville
Basic Double Room | 1 bedroom
Starlight Stays

Starlight Stays

Starlight Stays
2.5 star property
Manning
7.0 out of 10, Good, (7)
"It was nice for the area "
United States
Kendrell
The price is ฿1,915
฿2,126 total
includes taxes & fees
28 Dec - 29 Dec
Starlight Stays
Vending machine
Red Roof Inn Bishopville

Red Roof Inn Bishopville

Red Roof Inn Bishopville
2.0 star property
Bishopville
6.2 out of 10, (139)
"Clean room "
United States
Faith
The price is ฿2,333
฿2,613 total
includes taxes & fees
26 Dec - 27 Dec
Red Roof Inn Bishopville
Lobby
SpringHill Suites Sumter

SpringHill Suites Sumter

SpringHill Suites Sumter
2.5 star property
Sumter
9.4 out of 10, Exceptional, (452)
"Room is perfect"
United States
Sandy
The price is ฿3,888
฿4,355 total
includes taxes & fees
30 Dec - 31 Dec
SpringHill Suites Sumter
Lobby
Super 8 by Wyndham Sumter

Super 8 by Wyndham Sumter

Super 8 by Wyndham Sumter
2.0 star property
Sumter
7.2 out of 10, Good, (407)
"An accessible room had no bars near the toilet and the bed was extra high. "
United States
Omer
The price is ฿1,930
฿2,162 total
includes taxes & fees
31 Dec - 1 Jan 2026
Super 8 by Wyndham Sumter
Interior
Candlewood Suites Sumter by IHG

Candlewood Suites Sumter by IHG

Candlewood Suites Sumter by IHG
2.5 star property
Sumter
8.4 out of 10, Very good, (163)
"Excellent stay"
United States
Ashley
The price is ฿4,168
฿4,668 total
includes taxes & fees
26 Dec - 27 Dec
Candlewood Suites Sumter by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Mayesville

Venture to Riley Field and O'Donnell House—just two of the sights around Mayesville.

See all hotels in Mayesville
Somewhere in rural South Carolina off a back road to my hometown. Saw the sunflower field and had to stop.
Photo by Caroline Nunez
Open Photo by Caroline Nunez

Top Mayesville Hotel Reviews

Hyatt Place Sumter / Downtown

Hyatt Place Sumter / Downtown

10/10 Excellent
"Great space good breakfast and spacious rooms clean and comfortable "
Savia 2-night trip
Posted 5 days ago
Hyatt Place Sumter / Downtown

More cheap stays in Mayesville

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

2816 Paxville Highway Manning SC
The price is ฿2,644 per night from 1 Jan to 2 Jan
฿2,644
฿2,935 total
1 Jan - 2 Jan 2026
includes taxes & fees
8.4/10 Very Good! (1,001 reviews)

Frequently asked questions

What's the best place for a stay in Mayesville?
Tru by Hilton Sumter, located 11.1 mi (17.9 km) from the heart of Mayesville, is a top choice for your stay, based on our traveller data. Other good options for your visit to the area are Woodspring Suites Sumter Near Shaw Afb and Hyatt Place Sumter / Downtown. See all available top hotels, or vacation rentals in Mayesville.
If I need to cancel my hotel reservation in Mayesville, will I receive a refund?
Yes, most room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mayesville.
What is staying in Mayesville like?
Travellers to Mayesville will find plenty to explore and enjoy. There are 73 hotels and other accommodation options in the surrounding area. Find out more about Mayesville.
What are the top places to visit in Mayesville?
Places to visit in the wider area include Riley Field, O'Donnell House and Sumter Mall. You'll also find Palmetto Tennis Center and Swan Lake Iris Gardens in the area. Take a look at what more there is to see and do in Expedia's Mayesville guide.
What's the seasonal weather in Mayesville?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Mayesville is 1329 mm.