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Check prices for these dates

Next weekend
4 Sep - 6 Sep
In two weeks
11 Sep - 13 Sep

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Our top choices for Main Street Fort Pierce hotels

Lobby lounge

1. Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce
3.0 star property
7.7 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (1,005 reviews)
"Nice hotel, good location"
United States
Wilmer
The price is ฿3,068
฿3,436 total
includes taxes & fees
13 Sept - 14 Sept
Fairfield Inn & Suites by Marriott Fort Pierce
Lobby

2. Hampton Inn & Suites Ft. Pierce

Hampton Inn & Suites Ft. Pierce
2.5 star property
7.9 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (1,003 reviews)
"EVERYTHING WAS EXCELLENT"
United States
ROOSEVELT
The price is ฿2,959
฿3,315 total
includes taxes & fees
13 Sept - 14 Sept
Hampton Inn & Suites Ft. Pierce
Lobby

3. La Quinta Inn & Suites by Wyndham Ft. Pierce

La Quinta Inn & Suites by Wyndham Ft. Pierce
3.0 star property
7.9 km from Main Street Fort Pierce
8.4 out of 10, Very good, (1,001 reviews)
"Very clean friendly staff good breakfast"
United States
riad
The price is ฿2,914
฿3,263 total
includes taxes & fees
2 Sept - 3 Sept
La Quinta Inn & Suites by Wyndham Ft. Pierce
Terrace/patio

4. Home2 Suites by Hilton Ft. Pierce I-95

Home2 Suites by Hilton Ft. Pierce I-95
3.0 star property
7.8 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (269 reviews)
"Nice little breakfast...very clean and easy check in and check out..."
United States
JERRY
The price is ฿3,774
฿4,227 total
includes taxes & fees
12 Sept - 13 Sept
Home2 Suites by Hilton Ft. Pierce I-95
Lobby

5. Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
2.5 star property
8.3 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (881 reviews)
"Great place to stay."
United States
Melissa
The price is ฿3,344
฿3,746 total
includes taxes & fees
11 Sept - 12 Sept
Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
Outdoor spa tub

6. Hutchinson Island Hotel

Hutchinson Island Hotel
2.5 star property
3.1 km from Main Street Fort Pierce
8.2 out of 10, Very good, (1,393 reviews)
"Great place to stay and enjoy the beach!"
United States
Kathleen
The price is ฿3,177
฿4,180 total
includes taxes & fees
10 Sept - 11 Sept
Hutchinson Island Hotel
Room

7. Redfinn Inn

Redfinn Inn
2.5 star property
0.7 km from Main Street Fort Pierce
6.4 out of 10, (413 reviews)
The price is ฿1,743
฿1,953 total
includes taxes & fees
31 Aug - 1 Sept
Redfinn Inn
Restaurant

8. Days Inn & Suites by Wyndham Fort Pierce Midtown

Days Inn & Suites by Wyndham Fort Pierce Midtown
2.0 star property
4.5 km from Main Street Fort Pierce
7.0 out of 10, Good, (1,002 reviews)
"Nice staff and clean rooms but electrical issues and very limited breakfast choices. Price is ideal for budget travels for business."
United States
Janer
The price is ฿2,336
฿2,616 total
includes taxes & fees
1 Sept - 2 Sept
Days Inn & Suites by Wyndham Fort Pierce Midtown
Room

9. Comfort Suites Fort Pierce I-95

Comfort Suites Fort Pierce I-95
2.5 star property
7.7 km from Main Street Fort Pierce
7.8 out of 10, Good, (958 reviews)
"Clean rooms, friendly staff"
United States
Marina
The price is ฿2,758
฿3,089 total
includes taxes & fees
20 Sept - 21 Sept
Comfort Suites Fort Pierce I-95
Exterior

10. Red Roof Inn Ft Pierce

Red Roof Inn Ft Pierce
2.0 star property
4.6 km from Main Street Fort Pierce
7.2 out of 10, Good, (812 reviews)
"Decent"
United States
Colton
The price is ฿2,450
฿2,744 total
includes taxes & fees
31 Aug - 1 Sept
Red Roof Inn Ft Pierce
Breakfast meal

11. TownePlace Suites by Marriott Port St. Lucie I-95

TownePlace Suites by Marriott Port St. Lucie I-95
3.0 star property
21.9 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (1,005 reviews)
"I love the cleanliness of the rooms and property and the beautiful decor. Breakfast was also very good!"
United States
Melinda
The price is ฿3,248
฿3,638 total
includes taxes & fees
4 Sept - 5 Sept
TownePlace Suites by Marriott Port St. Lucie I-95
Pool

12. Best Western Port St. Lucie

Best Western Port St. Lucie
2.5 star property
14 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1,005 reviews)
"Great short term stay"
United States
Patsy
The price is ฿2,831
฿3,170 total
includes taxes & fees
13 Sept - 14 Sept
Best Western Port St. Lucie
Lobby

13. Rodeway Inn Fort Pierce US Highway 1

Rodeway Inn Fort Pierce US Highway 1
2.0 star property
2.9 km from Main Street Fort Pierce
6.8 out of 10, (124 reviews)
"Clean room, convenient location"
United States
Natalia
The price is ฿2,392
฿2,679 total
includes taxes & fees
29 Sept - 30 Sept
Rodeway Inn Fort Pierce US Highway 1
BBQ/picnic Area

14. Residence Inn by Marriott Port St. Lucie

Residence Inn by Marriott Port St. Lucie
3.0 star property
17.8 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (1,000 reviews)
The price is ฿3,344
฿3,746 total
includes taxes & fees
2 Sept - 3 Sept
Residence Inn by Marriott Port St. Lucie
Lobby

15. Hampton Inn & Suites Vero Beach Downtown

Hampton Inn & Suites Vero Beach Downtown
2.5 star property
22.1 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (1,001 reviews)
"Easy access and secure parking"
United States
Cameron
The price is ฿4,046
฿4,531 total
includes taxes & fees
6 Sept - 7 Sept
Hampton Inn & Suites Vero Beach Downtown
Property grounds

16. Road Runner Travel Resort - Caravan Park

Road Runner Travel Resort - Caravan Park
2.5 star property
7 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (102 reviews)
"Our family had an amazing stay, the pool was fun, everyone was friendly and our cabin was the perfect fit. "
United States
Benjamin
The price is ฿5,794
฿6,490 total
includes taxes & fees
31 Aug - 1 Sept
Road Runner Travel Resort - Caravan Park
Front of property

17. At Home Inn

At Home Inn
2.5 star property
8.2 km from Main Street Fort Pierce
8.0 out of 10, Very good, (1,268 reviews)
The price is ฿2,235
฿2,503 total
includes taxes & fees
31 Aug - 1 Sept
At Home Inn
Lobby

18. Days Inn & Suites by Wyndham Fort Pierce I-95

Days Inn & Suites by Wyndham Fort Pierce I-95
2.5 star property
7.8 km from Main Street Fort Pierce
7.4 out of 10, Good, (1,001 reviews)
"Clean rooms - great hotel to stay at!"
United States
Richard
The price is ฿1,979
฿2,216 total
includes taxes & fees
6 Sept - 7 Sept
Days Inn & Suites by Wyndham Fort Pierce I-95
Lobby

19. Sleep Inn Fort Pierce I-95

Sleep Inn Fort Pierce I-95
2.5 star property
7.9 km from Main Street Fort Pierce
7.6 out of 10, Good, (905 reviews)
"Recently remodeled, so it is a nice comfortable stay and of course, the staff is always amazing"
United States
Richard
The price is ฿2,474
฿2,771 total
includes taxes & fees
13 Sept - 14 Sept
Sleep Inn Fort Pierce I-95
Breakfast area

20. Hampton Inn & Suites Port St. Lucie, West

Hampton Inn & Suites Port St. Lucie, West
2.5 star property
17.4 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (1,002 reviews)
"I will definitely be staying there again!!"
United States
Nicholette
The price is ฿2,701
฿3,025 total
includes taxes & fees
12 Sept - 13 Sept
Hampton Inn & Suites Port St. Lucie, West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas for the activities you enjoy most.
A coastal area with a narrow waterway, a beach, and residential buildings.

Lakewood Park

When in Lakewood Park, you can plan a visit to McKee Botanical Garden and Harbor Branch Ocean Discovery Center, some noteworthy sights in the nearby area.

Spanish Lakes Country Club Village

While Spanish Lakes Country Club Village isn't home to many top sights, Harbor Branch Ocean Discovery Center and McKee Botanical Garden are some notable places to visit nearby.

A calm lake reflecting trees and a clear sky.

Spanish Lakes Fairways

While there might not be top attractions in Spanish Lakes Fairways, you can explore the larger area and discover places like Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse.

A coastal city with a bay, mangrove islands, and a clear blue sky.

Meadowood

While Meadowood isn't home to many top sights, Endless Summer Vineyard & Winery and Al's Family Farms are some notable places to visit nearby.

A mosaic sign with 'Mainstreet Fort Pierce' written on it.

Panther Woods

While Panther Woods may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Endless Summer Vineyard & Winery and Al's Family Farms.

Top Main Street Fort Pierce Hotel Reviews

Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina

Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina

10/10 Excellent
"Claro, quedaría más especial así: We had a wonderful experience at this hotel. The room was clean, comfortable, and very nice, and the staff was incredibly friendly and attentive. We were celebrating our honeymoon, and they made our stay even more special by giving us a beautiful newlywed welcome and decorating our room for the occasion. It was such a thoughtful gesture that we truly appreciated. We really enjoyed the location, the atmosphere, and the excellent service. Thank you for making our honeymoon stay so memorable. We would definitely come back and highly recommend this hotel!"
Karen 2-night trip
Posted 2 hours ago
Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina

Frequently asked questions

What is Main Street Fort Pierce like?
Main Street Fort Pierce is a neighbourhood that travellers like for its waterfront, art and shopping. Make sure that you visit Sunrise Theater and Fort Pierce City Marina as part of your Main Street Fort Pierce travel plans.
How many hotels will I find in Main Street Fort Pierce?
Book one of Expedia's 7 hotels and other accommodation options in Main Street Fort Pierce and start exploring everything Fort Pierce has to offer.
If I need to cancel my hotel reservation in Main Street Fort Pierce, will I receive a refund?
Yes! Most room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to get the best options available in Main Street Fort Pierce.
What is there to do in this Fort Pierce neighbourhood?
Sights like Sunrise Theater and Official Highwaymen Art Gallery can be part of your cultural tour of Main Street Fort Pierce. Fort Pierce City Marina and Fort Pierce Farmer's Market are also a couple of places to visit in the neighbourhood. A few places to visit in the area around Main Street Fort Pierce include Manatee Education and Observation Center, House of Seven Gables and A.E. Backus Museum. Marina at Fort Pierce and Causeway Cove are also worth a visit when you're out sightseeing in Fort Pierce.