Louisiana Holiday Rentals, Missouri: Private House Rentals

A river with a large, rusted metal bridge and a smaller bridge in the background.

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Our top choices for Louisiana hotels

A gazebo with a table and benches, surrounded by trees and a body of water.

A hotel room with a desk, a television, a chair, a small refrigerator, a lamp, and a plant.

A hotel room with a bed, two sofas, a small table, a desk with a chair, a TV, and a potted plant.

A hotel room with a bed, a desk, a chair, a television, a microwave, and a lamp.

1. River's Edge Motel

Louisiana

Kim

฿2,791

฿3,169 total

includes taxes & fees

14 Oct - 15 Oct

A restaurant with a bar area, wooden flooring, checkered tablecloths, and a brick wall.

A row of multi-story buildings with a variety of storefronts, including a coffee shop and a restaurant.

A downtown area with a mix of historic and modern buildings, a prominent Mercantile Bank, and a view of a lake.

A staircase with wooden steps and a wooden handrail, leading up a brick wall.

2. The Eagles Nest Inn

Louisiana

Kimberly

฿3,935

฿4,468 total

includes taxes & fees

2 Nov - 3 Nov

A cozy living area with a leather sofa, a wooden coffee table, and a patterned armchair. A brick wall and wooden shelves with various items are visible.

A storefront with a sign reading "105 EAST WASHINGTON STREET PITTSFIELD, ILLINOIS 62363".

A cozy indoor space with a round table and chairs, a bookshelf with books, and a ceiling fan.

A cozy interior with a round dining table, chairs, a chandelier, and a view through large windows.

3. William Watson Hotel

Pittsfield

Mary

฿2,850

฿3,134 total

includes taxes & fees

15 Oct - 16 Oct

A hallway with wooden doors leading to a dining area with a table and chairs.

A kitchen with wooden cabinets, a granite countertop, and a built-in sink.

A hotel corridor with a wooden railing, a ceiling fan, and a lamp.

A neatly made bed with a headboard, two bedside tables with lamps, a waste bin, and a window with curtains.

4. Green Acres Hotel

Pittsfield

Kimberly

฿3,962

฿4,358 total

includes taxes & fees

14 Oct - 15 Oct

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A hotel kitchen with a buffet setup, including a coffee station and various food items.

A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

5. Best Western On The River

Hannibal

Wei

฿3,688

฿4,254 total

includes taxes & fees

21 Oct - 22 Oct

A hallway with a light blue wall, wooden shelves, and a door marked with the number 2.

A white building with a covered porch, numbered doors, and outdoor seating.

A cozy living room with a wooden dresser, a sofa, and a dining area with a table and chairs.

A cozy living room with a wooden coffee table, a sofa, and a chair. There are potted plants and a television on the wall.

6. Monroe Street Suites

Pittsfield

Isidro

฿3,159

฿3,475 total

includes taxes & fees

14 Oct - 15 Oct

A bakery display with various baked goods and packaged snacks.

A bathroom with a shower, tiled walls, and a wooden floor.

A two-story building with a brick facade, large windows, and a flat roof.

A hotel room with two beds, a bedside table with a lamp, a window with curtains, and a mirror on the wall.

7. Rodeway Inn Pittsfield

Pittsfield

Teresa

฿2,089

฿2,297 total

includes taxes & fees

1 Nov - 2 Nov

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

8. Sleep Inn & Suites Hannibal West

Hannibal

Patricia

฿3,974

฿4,623 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a bed, a sofa, a desk, and a lamp.

A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.

9. Comfort Inn & Suites - Hannibal

Hannibal

Jerry

฿2,607

฿3,108 total

includes taxes & fees

8 Nov - 9 Nov

A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

A hotel room with a large bed, a desk with a chair, a window with curtains, and a wall-mounted artwork.

A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

A long hallway with a patterned carpet, wooden paneling on the walls, and a ceiling light.

10. Super 8 by Wyndham Hannibal

Hannibal

Betty

฿2,070

฿2,388 total

includes taxes & fees

21 Oct - 22 Oct

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

A hotel entrance with a central fountain, large columns, and a clear sky.

A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

11. Quality Inn & Suites Hannibal West

Hannibal

Gayle

฿2,553

฿2,970 total

includes taxes & fees

8 Nov - 9 Nov

A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

A coffee station with a coffee machine, cups, and a sign that says "RISE & SHINE."

A building with a covered entrance and a sign indicating a clearance height of 13 feet.

12. Motel 6 Hannibal, MO

Hannibal

Donna B

฿1,944

฿2,243 total

includes taxes & fees

21 Oct - 22 Oct

An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.

A hotel room with a bed, a desk with a chair, a television, and a desk lamp.

A kitchen with a granite countertop, wooden cabinets, and a herringbone-patterned floor.

A clean, modern reception area with a reception desk, a clock, and a potted plant.

13. Baymont by Wyndham Hannibal

Hannibal

brian

฿1,853

฿2,151 total

includes taxes & fees

18 Oct - 19 Oct

A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

A kitchen with wooden cabinets, a granite countertop, and various food items and kitchen appliances.

A hotel room with two beds, a desk, a chair, and a telephone.

A modern building with a red awning, a parking lot, and a sign indicating an entrance.

14. Howard Johnson BY Wyndham Hannibal

Hannibal

Debbie

฿1,962

฿2,278 total

includes taxes & fees

25 Oct - 26 Oct

A reception area with a marble counter, a 'Days Inn' sign, and a welcome mat.

A hotel room with two beds, a desk with a computer, a television, and a small seating area.

A hotel room with a dining area, kitchenette, and a door leading to a hallway.

A laundry room with a washing machine, dryer, and a shelf with detergent bottles.

15. Days Inn by Wyndham Hannibal

Hannibal

Christian

฿1,995

฿2,302 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.

A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.

A swimming pool with lounge chairs and a covered seating area.

16. Lighthouse Inn & Suites

Hannibal

Connie

฿5,358

฿7,344 total

includes taxes & fees

14 Oct - 15 Oct

A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.

A historic building with a stone facade and multiple windows, featuring a sign about Tom Sawyer's fence.

A compact kitchen with a refrigerator, microwave, and sink.

17. Riverside Inn Hannibal

Hannibal

Janee

฿5,052

฿6,992 total

includes taxes & fees

18 Oct - 19 Oct

A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

A fireplace with decorative elements, framed pictures, and a vase of red flowers.

A large, two-story house with a porch and a sign indicating 'ONE WAY'.

A cozy living room with a fireplace, a red armchair, a globe, and various framed pictures on the mantel.

18. Garden House Bed and Breakfast

Hannibal

Debbie

฿3,575

฿4,124 total

includes taxes & fees

15 Oct - 16 Oct

A rooftop terrace with a brick wall, a metal railing, and a table with chairs.

A rustic living room with exposed brick walls, wooden beams, and a cozy fireplace. There are two leather sofas with throw pillows and a fluffy rug.

A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a trash bin.

A storefront with a red and gray facade, large windows, and various beer advertisements.

19. Deck + River View: Loft in Downtown Hannibal

Hannibal

฿4,627

฿8,886 total

includes taxes & fees

15 Oct - 16 Oct

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Learn more about Louisiana

Like rivers? Get away to relaxing Louisiana!

See all hotels in Louisiana

Top Louisiana Hotel Reviews

Quality Inn & Suites Hannibal West

8/10 Good

"Overall the room was clean."

The Eagles Nest Inn

10/10 Excellent

"Cutest place to stay in Louisiana Missouri"

Garden House Bed and Breakfast

8/10 Good

"Beautiful Queen Ann B&B, was reasonably priced and within walking distance to the river and down town Hannibal attractions."

Days Inn by Wyndham Hannibal

10/10 Excellent

"Everything was 5 star rating except the coffee from the automatic coffee dispenser."

William Watson Hotel

10/10 Excellent

"Everything was excellent. Very nice and friendly and helpful"

River's Edge Motel

10/10 Excellent

"we enjoyed our stay at rivers edge. the view was amazing overlooking the Mississippi river. very quaint town and the murals are worth the drive by. room was very clean and the beds were very comfortable. would stay again"

Riverside Inn Hannibal

10/10 Excellent

"Beautiful view of the river! Easy access to downtown and shops/restaurants. The jacuzzi was wonderful and a nice bonus! We’ll definitely stay there again if we’re back in the area."

Monroe Street Suites

10/10 Excellent

"Best place Ive stayed period. 100 percent recommend"

Comfort Inn & Suites - Hannibal

10/10 Excellent

"Rooms were clean. Staff was friendly."

More cheap stays in Louisiana

Baymont by Wyndham Hannibal

4141 Market St Hannibal MO

฿1,853

฿2,151 total

18 Oct - 19 Oct

includes taxes & fees

Motel 6 Hannibal, MO

123 Huckleberry Heights Dr Hannibal MO

฿1,944

฿2,243 total

21 Oct - 22 Oct

includes taxes & fees

Quality Inn & Suites Hannibal West

120 Lindsey Drive Hannibal MO

฿2,553

฿2,970 total

8 Nov - 9 Nov

includes taxes & fees

8/10 Very good! (1,003 reviews)

Comfort Inn & Suites - Hannibal

4000 Market St Hannibal MO

฿2,607

฿3,108 total

8 Nov - 9 Nov

includes taxes & fees

7.6/10 Good! (762 reviews)

Best Western On The River

401 North 3rd Street Hannibal MO

฿3,688

฿4,254 total

21 Oct - 22 Oct

includes taxes & fees

Sleep Inn & Suites Hannibal West

105 Lakeside Dr Hannibal MO

฿3,974

฿4,623 total

8 Nov - 9 Nov

includes taxes & fees

Frequently asked questions

Where is the best place to stay in Louisiana?

Based on our traveller data, The Eagles Nest Inn is one of the top choices for your stay. This inn is a short 3-minute walk from Mississippi River, and it offers a restaurant and free parking. River's Edge Motel is another good option for your visit. See all available top hotels, or vacation rentals in Louisiana.

If I need to cancel my hotel reservation in Louisiana, will I receive a refund?

Yes, most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Louisiana.

What's the best dog-friendly place to stay in Louisiana?

River's Edge Motel is a top dog-friendly option for your stay. See more pet-friendly hotel accommodations in Louisiana.

What are some hotels with pools in Louisiana?

Quality Inn & Suites Hannibal West: Features a snack bar/deli, an indoor pool and buffet. Best Western On The River and Comfort Inn & Suites - Hannibal are two additional hotels with an on-site pool. View all hotels with pools in Louisiana.

What is staying in Louisiana like?

Visitors to Louisiana will definitely enjoy the riverfront. This city also attracts tourists with its welcoming and relaxing setting. In Louisiana, there are 5 hotels and other accommodation options to choose from. Find out more about Louisiana.

What are the top places to visit in Louisiana?

A favourite place to visit is Mississippi River. You'll also find Clarksville State Game Refuge and Clarksville Riverfront Park in the area. Take a look at what more there is to see and do in Expedia's Louisiana guide.

What's the seasonal weather in Louisiana?

The hottest months are usually July and August, with an average temperature of 23°C, while the coldest months are January and February, with an average of 2°C. Average annual precipitation for Louisiana is 1234 mm.

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Book Hotels in Louisiana on Expedia.com

Find hotels in Louisiana, MO from ฿2,151

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Louisiana

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Louisiana hotels

1. River's Edge Motel

2. The Eagles Nest Inn

3. William Watson Hotel

4. Green Acres Hotel

5. Best Western On The River

6. Monroe Street Suites

7. Rodeway Inn Pittsfield

8. Sleep Inn & Suites Hannibal West

9. Comfort Inn & Suites - Hannibal

10. Super 8 by Wyndham Hannibal

11. Quality Inn & Suites Hannibal West

12. Motel 6 Hannibal, MO

13. Baymont by Wyndham Hannibal

14. Howard Johnson BY Wyndham Hannibal

15. Days Inn by Wyndham Hannibal

16. Lighthouse Inn & Suites

17. Riverside Inn Hannibal

18. Garden House Bed and Breakfast

19. Deck + River View: Loft in Downtown Hannibal

Learn more about Louisiana

Top Louisiana Hotel Reviews

Quality Inn & Suites Hannibal West

The Eagles Nest Inn

Garden House Bed and Breakfast

Days Inn by Wyndham Hannibal

William Watson Hotel

River's Edge Motel

Riverside Inn Hannibal

Monroe Street Suites

Comfort Inn & Suites - Hannibal

More cheap stays in Louisiana

Baymont by Wyndham Hannibal

Motel 6 Hannibal, MO

Quality Inn & Suites Hannibal West

Comfort Inn & Suites - Hannibal

Best Western On The River

Sleep Inn & Suites Hannibal West

Frequently asked questions

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