TOP Gay-Friendly Hotels in Knoxville, MD for 2026

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Our top choices for Knoxville LGBT-friendly hotels

1. Holiday Inn Express & Suites Brunswick - Harpers Ferry Area by IHG

Knoxville

Cynthia

฿3,780

฿4,196 total

includes taxes & fees

8 Sept - 9 Sept

2. Holiday Inn Express Charles Town by IHG

Charles Town

IRIS

฿3,913

฿4,422 total

includes taxes & fees

8 Sept - 9 Sept

3. Hampton Inn & Suites Charles Town

Charles Town

Sarah

฿4,324

฿4,843 total

includes taxes & fees

8 Sept - 9 Sept

In-room safe, desk, blackout curtains, iron/ironing board

4. Home2 Suites by Hilton Charles Town

Charles Town

Matthew

฿4,868

฿5,452 total

includes taxes & fees

8 Sept - 9 Sept

5. Hilton Garden Inn Frederick

Frederick

Alfredo

฿3,794

฿4,211 total

includes taxes & fees

7 Sept - 8 Sept

6. Fairfield Inn & Suites by Marriott Frederick

Frederick

Ruby

฿4,212

฿4,675 total

includes taxes & fees

13 Sept - 14 Sept

In-room safe, desk, laptop workspace, iron/ironing board

7. SpringHill Suites by Marriott Frederick

Frederick

William

฿4,149

฿4,605 total

includes taxes & fees

9 Sept - 10 Sept

8. Courtyard by Marriott Frederick

Frederick

Gayle

฿4,046

฿4,491 total

includes taxes & fees

13 Sept - 14 Sept

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Frequently asked questions

Searching for an LGBTQ-friendly hotel in Knoxville?

Whether you are travelling with your partner or flying solo, you'll find gay-friendly hotels in Knoxville on our website. Discover the people, places and traditions found only in Knoxville.

What is the favourite LGBTQ-friendly place to stay in Knoxville?

Holiday Inn Express & Suites Brunswick - Harpers Ferry Area by IHG is a top LGBTQ-friendly hotel, and features free Wi-Fi and Smart TVs.

What is there to see in Knoxville?

During your trip, get out and enjoy everything Knoxville has to offer. You and your travelling companions may want to visit Maryland Heights, South Mountain State Park and Shenandoah River. While you're here, create some great memories of your trip with stops at Potomac River, Lockhouse 33 and Catoctin Valley.

What is an LGBTQ-friendly hotel in Knoxville?

LGBTQ-friendly hotels are places where lesbian, gay, bisexual and transgender travellers are proudly welcomed. Expedia has worked with the International Gay and Lesbian Travel Association (IGLTA) to compile a selection of LGBTQ-friendly hotels worldwide. In Knoxville, hotels affiliated with IGLTA prioritise a diverse environment in which guests are welcomed, respected and not obliged to declare or hide their sexual orientation.

What can I expect from an LGBTQ-friendly Knoxville hotel?

Stay at an LGBTQ-friendly hotel in Knoxville and you won't have to hide or your sexuality or your gender identity when you check in. Many of our LGBTQ-friendly accommodation options offer concierge services that provide information about nearby LGBTQ restaurants and local events.

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Change your mind

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Check availability on Knoxville Gay-Friendly Hotels

Our top choices for Knoxville LGBT-friendly hotels

1. Holiday Inn Express & Suites Brunswick - Harpers Ferry Area by IHG