Uptown - Upper Duval Travel Guide

Key West

Key West Butterfly and Nature Conservatory featuring flowers, zoo animals and animals
Key West Butterfly and Nature Conservatory featuring flowers, zoo animals and animals
South Beach which includes a sandy beach and a coastal town as well as a large group of people
South Beach featuring swimming, a luxury hotel or resort and a sandy beach
Key West Butterfly and Nature Conservatory showing signage

Popular places to visit

Southernmost Point

Southernmost Point

4/5(39 reviews)

Snap a memorable photograph from the edge of North America at this monumental landmark.

Southernmost Point
South Beach

South Beach

4.5/5(8 reviews)

The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

South Beach
Key West Butterfly and Nature Conservatory showing animals, food and zoo animals

Key West Butterfly and Nature Conservatory

4.5/5(10 reviews)

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

Key West Butterfly and Nature Conservatory

Things to do

Florida: Key West Overseas Highway Self-Driving Tour

Florida: Key West Overseas Highway App-Based Driving Audio Tour

฿468
per traveller
78% of travellers recommend
Florida: Key West Overseas Highway App-Based Driving Audio Tour
Bahama Village Walking Tour

Bahama Village Walking Tour

฿972
per adult
Bahama Village Walking Tour
Key West’s Old Town Treasures: A Self-Guided Audio Tour

Key West’s Old Town Treasures: A Self-Guided Audio Tour

฿486
per adult
Key West’s Old Town Treasures: A Self-Guided Audio Tour
Florida Key West Self-Guided Walking Audio Tour

Florida Key West Self-Guided Walking Audio Tour Via App

฿275
per traveller
Florida Key West Self-Guided Walking Audio Tour Via App
Climb the 88 stairs to the top of the Key West Lighthouse.

Maritime Village to Micro State: A Self Guided Tour of Key West

฿389
per adult
Maritime Village to Micro State: A Self Guided Tour of Key West
Key West History And Culture Walking Tour

Southernmost Key West History and Culture Small-Group Walking Tour

฿1,296
per adult
Southernmost Key West History and Culture Small-Group Walking Tour
See all activities in Key West

Top hotels in Uptown - Upper Duval

Southernmost Beach Resort and Guesthouses
Southernmost Beach Resort and Guesthouses
4 out of 5
1319 Duval Street, Key West, FL
The price is ฿7,432 per night from 14 Jul to 15 Jul
฿7,432
฿10,555 total
14 Jul - 15 Jul
includes taxes & fees
Stay at this 4-star beach hotel in Key West. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the bar in their reviews. ...
8.6/10 Excellent! (2,549 reviews)
"Good accommodation cleanness variety of activities good location we had a great time"

Reviewed on 24 Jun 2025

Southernmost Beach Resort and Guesthouses
The Reach Key West, Curio Collection by Hilton
The Reach Key West, Curio Collection by Hilton
4 out of 5
1435 Simonton Street, Key West, FL
The price is ฿8,324 per night from 8 Jul to 9 Jul
฿8,324
฿11,317 total
8 Jul - 9 Jul
includes taxes & fees
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (999 reviews)
"The staff was very nice. The restaurant at the hotel offered food with impeccable taste."

Reviewed on 25 Jun 2025

The Reach Key West, Curio Collection by Hilton
The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
The price is ฿6,152 per night from 7 Jul to 8 Jul
฿6,152
฿8,385 total
7 Jul - 8 Jul
includes taxes & fees
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...
8/10 Very Good! (1,101 reviews)
"Really nice property, excellent value, friendly staff, great area"

Reviewed on 25 Jun 2025

The Southernmost Inn - Adults Only
Orchid Key Inn - Adults Only
Orchid Key Inn - Adults Only
3.5 out of 5
1004 Duval St, Key West, FL
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...
9.8/10 Exceptional! (1,004 reviews)
"We enjoyed this property so much that extended our stay another day. The breakfast and the evening social were nothing but lovely. It draws a very nice clientele and the staff all were helpful, knowledgeable, and kind. We will definitely go back!"

Reviewed on 25 Jun 2025

Get rates
Orchid Key Inn - Adults Only
Southernmost House
Southernmost House
4 out of 5
1400 Duval Street, Key West, FL
The price is ฿6,699 per night from 9 Jul to 10 Jul
฿6,699
฿10,096 total
9 Jul - 10 Jul
includes taxes & fees
Stay at this 4-star beach hotel in Key West. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (998 reviews)
"Beautiful, romantic location right on the water. Infinity pool overlooking the Gulf. We stayed in Bungalow 103 which was right next to the pool and had a view of the ocean. Room was great with kitchen and walk in shower. We will be back!!"

Reviewed on 21 Jun 2025

Southernmost House
Southwinds Motel
Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL
The price is ฿5,013 per night from 1 Jul to 2 Jul
฿5,013
฿6,554 total
1 Jul - 2 Jul
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and a 24-hour front desk. Our guests praise the breakfast and the pool in their reviews. ...
8.6/10 Excellent! (1,118 reviews)
"Was very clean, air conditioner worked very well, pool was good, but closed pretty early. Great value considering its one of the cheaper places in Kwy West. Will definitely be staying there for our next trip."

Reviewed on 25 Jun 2025

Southwinds Motel
See all 2,807 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

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Old Town Key West

5/5(6 area reviews)

While visiting Old Town Key West, you might make a stop by sights like Duval Street and Saint Mary Star of the Sea.

Old Town Key West
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Downtown Key West

While visiting Downtown Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.

Downtown Key West
Harry S. Truman Little White House which includes a house and cycling

Bahama Village

5/5(1 area review)

Bahama Village is noteworthy for its historical sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
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Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
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Key West Historic District

4.5/5(66 area reviews)

Travellers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to stop by Duval Street and Saint Mary Star of the Sea.

Key West Historic District
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White Street Gallery District

If you're looking for some top things to see and do in White Street Gallery District and surrounding area, you can visit Duval Street and Saint Mary Star of the Sea.

White Street Gallery District

Uptown - Upper Duval Travel Guide