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Our top choices for Isle of Palms South hotels

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.5 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,077 reviews)
"Location was very convenient"
United States
Thomas
The price is ฿4,231
฿4,802 total
includes taxes & fees
12 Jul - 13 Jul
Hyatt Place Jacksonville / St. Johns Town Center

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.2 km from Isle of Palms South
8.8 out of 10, Excellent, (1,000 reviews)
"Nice staff and very clean"
United States
Amber
The price is ฿3,326
฿3,775 total
includes taxes & fees
12 Jul - 13 Jul
Holiday Inn Express Jacksonville - Blount Island by IHG

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
22.1 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,672 reviews)
"One of the best places I’ve stayed at. Great food and friendly staff."
United States
Cynthia
The price is ฿6,652
฿7,625 total
includes taxes & fees
1 Jul - 2 Jul
Hyatt Regency Jacksonville

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Oceanfront, 4.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (4,094 reviews)
"Great room and very convenient location"
United States
Lyndi
The price is ฿5,561
฿6,312 total
includes taxes & fees
5 Jul - 6 Jul
Margaritaville Jacksonville Beach

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
8.7 km from Isle of Palms South
9.6 out of 10, Exceptional, (111 reviews)
"I really like this location and would definitely stay here again."
United States
Althia
The price is ฿3,930
฿4,460 total
includes taxes & fees
18 Jul - 19 Jul
Hyatt Studios Jacksonville/St Johns Town Center

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.2 km from Isle of Palms South
9.2 out of 10, Wonderful, (363 reviews)
"really enjoyed my stay at the hotel"
United States
Stacy
The price is ฿4,425
฿5,022 total
includes taxes & fees
16 Jul - 17 Jul
Home2 Suites By Hilton Jacksonville Downtown

Hampton Inn & Suites Jacksonville South - Bartram Park

Hampton Inn & Suites Jacksonville South - Bartram Park
3.0 star property
18.4 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,005 reviews)
"The hotel was located in a great area! Plenty of restaurants near the hotel!"
United States
Terri
The price is ฿3,109
฿3,529 total
includes taxes & fees
26 Jul - 27 Jul
Hampton Inn & Suites Jacksonville South - Bartram Park

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.8 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,003 reviews)
"Very enjoyable stay!"
United States
Kristin
The price is ฿4,336
฿4,835 total
includes taxes & fees
19 Jul - 20 Jul
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
Oceanfront, 4.6 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,006 reviews)
"Great stay"
United States
Adam
The price is ฿5,055
฿5,738 total
includes taxes & fees
5 Jul - 6 Jul
Best Western Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
Oceanfront, 5.2 km from Isle of Palms South
8.6 out of 10, Excellent, (1,008 reviews)
"Great location, great staff."
United States
Donna
The price is ฿7,616
฿8,645 total
includes taxes & fees
21 Jul - 22 Jul
Courtyard by Marriott Jacksonville Beach Oceanfront

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.1 km from Isle of Palms South
7.6 out of 10, Good, (533 reviews)
"The hotel was clean and staff was proficient."
United States
Maxine
The price is ฿2,429
฿2,757 total
includes taxes & fees
6 Jul - 7 Jul
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.7 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,002 reviews)
"Everyone was very nice and the rooms were clean."
United States
Camille
The price is ฿4,024
฿4,568 total
includes taxes & fees
19 Jul - 20 Jul
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.8 km from Isle of Palms South
8.8 out of 10, Excellent, (722 reviews)
"We liked the hotel, it was a nice experience. We all had a good time."
United States
Shannon
The price is ฿5,063
฿6,502 total
includes taxes & fees
6 Jul - 7 Jul
Seahorse Oceanfront Inn

San Marco Inn East

San Marco Inn East
3.0 star property
19.5 km from Isle of Palms South
8.6 out of 10, Excellent, (1,428 reviews)
"Excellent stay"
United States
shawn
The price is ฿2,289
฿2,598 total
includes taxes & fees
4 Jul - 5 Jul
San Marco Inn East

Courtyard by Marriott Jacksonville I-295/East Beltway

Courtyard by Marriott Jacksonville I-295/East Beltway
3.0 star property
13.2 km from Isle of Palms South
9.2 out of 10, Wonderful, (711 reviews)
"The breakfast is fabulous "
United States
Ana Maria Román
The price is ฿3,625
฿4,115 total
includes taxes & fees
1 Jul - 2 Jul
Courtyard by Marriott Jacksonville I-295/East Beltway

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
9.8 km from Isle of Palms South
9.6 out of 10, Exceptional, (112 reviews)
"Great staff and breakfast!"
United States
Kandi
The price is ฿4,457
฿5,058 total
includes taxes & fees
12 Jul - 13 Jul
TownePlace Suites by Marriott® Jacksonville Mayport

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,157 reviews)
"Great location not too far from beaches restsurants, and shopping."
United States
Donna L.
The price is ฿4,559
฿5,175 total
includes taxes & fees
26 Jul - 27 Jul
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
8.9 km from Isle of Palms South
9.4 out of 10, Exceptional, (213 reviews)
"Loved our stay"
United States
Jaime
The price is ฿5,953
฿6,757 total
includes taxes & fees
2 Jul - 3 Jul
AC Hotel Jacksonville St Johns Town Center

Residence Inn by Marriott Jacksonville Downtown

Residence Inn by Marriott Jacksonville Downtown
3.0 star property
24 km from Isle of Palms South
9.6 out of 10, Exceptional, (425 reviews)
"Great stay"
United States
Chennoyvia
The price is ฿4,973
฿5,645 total
includes taxes & fees
2 Jul - 3 Jul
Residence Inn by Marriott Jacksonville Downtown

The Hotel Palms Courtyard

The Hotel Palms Courtyard
3.5 star property
6.6 km from Isle of Palms South
9.6 out of 10, Exceptional, (308 reviews)
"Clean, room was very nice, staff was helpful"
United States
Angela
The price is ฿6,322
฿7,176 total
includes taxes & fees
1 Jul - 2 Jul
The Hotel Palms Courtyard
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms South

Find the best Isle of Palms South areas for the activities you enjoy most.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Oceanfront

While visiting Oceanfront, you might make a stop by sights like Oceanfront Park and Northeast Florida Beaches.

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Top Isle of Palms South Hotel Reviews

Frequently asked questions

What is Isle of Palms South like?
Travellers will be sure to find plenty to entertain them in Jacksonville Beach's Isle of Palms South neighbourhood.
How many hotels can I expect to find in Isle of Palms South?
Expedia has 7 Isle of Palms South hotels and other accommodation options, and one might make a good home base for venturing out into the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms South, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view the best deals in Isle of Palms South.
What are the top things to see and do in Isle of Palms South?
Cradle Creek Preserve, Windsor Parke Golf Club and Jacksonville Beach Golf Club are just a few of the places to visit in and around Isle of Palms South. Windsor Commons Shopping Center and Harbor City Municipal Golf Course are also worth a visit when you're out sightseeing in Jacksonville Beach.