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Our top choices for Isle of Palms South hotels

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
22.1 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,660 reviews)
"One of the best places I’ve stayed at. Great food and friendly staff."
United States
Cynthia
The price is ฿6,592
฿7,557 total
includes taxes & fees
6 Jul - 7 Jul
Hyatt Regency Jacksonville

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Oceanfront, 4.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (4,072 reviews)
"Great room and very convenient location"
United States
Lyndi
The price is ฿5,562
฿6,313 total
includes taxes & fees
5 Jul - 6 Jul
Margaritaville Jacksonville Beach

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.2 km from Isle of Palms South
8.8 out of 10, Excellent, (1,001 reviews)
"Nice staff and very clean"
United States
Amber
The price is ฿3,230
฿3,666 total
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Express Jacksonville - Blount Island by IHG

Weekly Inn

Weekly Inn
2.0 star property
14.7 km from Isle of Palms South
7.6 out of 10, Good, (1,333 reviews)
"We understand for one night but it is a very clean neat place"
United States
Ramon
The price is ฿1,780
฿2,020 total
includes taxes & fees
1 Jul - 2 Jul
Weekly Inn

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.5 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,069 reviews)
"Location was very convenient"
United States
Thomas
The price is ฿4,232
฿4,803 total
includes taxes & fees
28 Jun - 29 Jun
Hyatt Place Jacksonville / St. Johns Town Center

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.2 km from Isle of Palms South
9.2 out of 10, Wonderful, (357 reviews)
"really enjoyed my stay at the hotel"
United States
Stacy
The price is ฿4,027
฿4,571 total
includes taxes & fees
2 Jul - 3 Jul
Home2 Suites By Hilton Jacksonville Downtown

Hampton Inn & Suites Jacksonville South - Bartram Park

Hampton Inn & Suites Jacksonville South - Bartram Park
3.0 star property
18.4 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,000 reviews)
"The hotel was located in a great area! Plenty of restaurants near the hotel!"
United States
Terri
The price is ฿3,081
฿3,497 total
includes taxes & fees
13 Jul - 14 Jul
Hampton Inn & Suites Jacksonville South - Bartram Park

San Marco Inn East

San Marco Inn East
3.0 star property
19.5 km from Isle of Palms South
8.6 out of 10, Excellent, (1,420 reviews)
"Excellent stay"
United States
shawn
The price is ฿2,268
฿2,574 total
includes taxes & fees
30 Jun - 1 Jul
San Marco Inn East

Midtown Lodge

Midtown Lodge
2.5 star property
18.9 km from Isle of Palms South
8.0 out of 10, Very good, (686 reviews)
"The rooms are nice and clean and it’s peaceful"
United States
Jerrica
The price is ฿1,886
฿2,141 total
includes taxes & fees
25 Jun - 26 Jun
Midtown Lodge

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
8.9 km from Isle of Palms South
9.4 out of 10, Exceptional, (211 reviews)
"Loved our stay"
United States
Jaime
The price is ฿5,900
฿6,696 total
includes taxes & fees
25 Jun - 26 Jun
AC Hotel Jacksonville St Johns Town Center

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.1 km from Isle of Palms South
7.6 out of 10, Good, (527 reviews)
"The hotel was clean and staff was proficient."
United States
Maxine
The price is ฿2,407
฿2,732 total
includes taxes & fees
29 Jun - 30 Jun
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,003 reviews)
"Very enjoyable stay!"
United States
Kristin
The price is ฿4,189
฿4,671 total
includes taxes & fees
6 Jul - 7 Jul
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.7 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,006 reviews)
"Everyone was very nice and the rooms were clean."
United States
Camille
The price is ฿3,988
฿4,527 total
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Wingate by Wyndham Jacksonville FL

Wingate by Wyndham Jacksonville FL
3.0 star property
15.2 km from Isle of Palms South
7.4 out of 10, Good, (1,000 reviews)
"Clean room great staff always were helpful nice breakfast excellent housekeepers"
United States
Steven
The price is ฿2,225
฿2,525 total
includes taxes & fees
30 Jun - 1 Jul
Wingate by Wyndham Jacksonville FL

Wyndham Garden Jacksonville

Wyndham Garden Jacksonville
3.0 star property
15.3 km from Isle of Palms South
8.0 out of 10, Very good, (1,912 reviews)
"I enjoyed the stay"
United States
Siddiq
The price is ฿2,729
฿3,098 total
includes taxes & fees
1 Jul - 2 Jul
Wyndham Garden Jacksonville

Fairfield Inn by Marriott Jacksonville Orange Park

Fairfield Inn by Marriott Jacksonville Orange Park
3.0 star property
27.9 km from Isle of Palms South
7.8 out of 10, Good, (754 reviews)
"Good"
United States
Wilfrid
The price is ฿2,340
฿2,633 total
includes taxes & fees
28 Jun - 29 Jun
Fairfield Inn by Marriott Jacksonville Orange Park

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,142 reviews)
"Great location not too far from beaches restsurants, and shopping."
United States
Donna L.
The price is ฿4,560
฿5,176 total
includes taxes & fees
5 Jul - 6 Jul
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
Oceanfront, 5.2 km from Isle of Palms South
8.6 out of 10, Excellent, (1,001 reviews)
"Great location, great staff."
United States
Donna
The price is ฿6,953
฿7,892 total
includes taxes & fees
30 Jun - 1 Jul
Courtyard by Marriott Jacksonville Beach Oceanfront

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
9.8 km from Isle of Palms South
9.6 out of 10, Exceptional, (112 reviews)
"Great staff and breakfast!"
United States
Kandi
The price is ฿4,713
฿5,350 total
includes taxes & fees
1 Jul - 2 Jul
TownePlace Suites by Marriott® Jacksonville Mayport

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
8.7 km from Isle of Palms South
9.6 out of 10, Exceptional, (102 reviews)
"I really like this location and would definitely stay here again."
United States
Althia
The price is ฿3,931
฿4,461 total
includes taxes & fees
30 Jun - 1 Jul
Hyatt Studios Jacksonville/St Johns Town Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms South

Find the best Isle of Palms South areas for the activities you enjoy most.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

Oceanfront

While visiting Oceanfront, you might make a stop by sights like Oceanfront Park and Northeast Florida Beaches.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Top Isle of Palms South Hotel Reviews

Frequently asked questions

What is Isle of Palms South like?
Travellers will be sure to find plenty to entertain them in Jacksonville Beach's Isle of Palms South neighbourhood.
How many hotels can I expect to find in Isle of Palms South?
Expedia has 7 Isle of Palms South hotels and other accommodation options, and one might make a good home base for venturing out into the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms South, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view the best deals in Isle of Palms South.
What are the top things to see and do in Isle of Palms South?
Cradle Creek Preserve, Windsor Parke Golf Club and Jacksonville Beach Golf Club are just a few of the places to visit in and around Isle of Palms South. Windsor Commons Shopping Center and Harbor City Municipal Golf Course are also worth a visit when you're out sightseeing in Jacksonville Beach.