Search Hotels in Isle of Palms South, Jacksonville

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Our top choices for Isle of Palms South hotels

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.2 km from Isle of Palms South
8.8 out of 10, Excellent, (1,000 reviews)
"Room was clean and staff is always friendly. "
United States
Cary Jo
The price is ฿3,231
฿3,667 total
includes taxes & fees
16 Mar - 17 Mar
Holiday Inn Express Jacksonville - Blount Island by IHG

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.5 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,007 reviews)
"very friendly staff!! i love staying here!!"
United States
Evani
The price is ฿3,611
฿4,098 total
includes taxes & fees
5 Apr - 6 Apr
Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
22.1 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,539 reviews)
"The room was great with the river view, clean and the staff was great! "
United States
OLGA
The price is ฿4,846
฿5,555 total
includes taxes & fees
3 Apr - 4 Apr
Hyatt Regency Jacksonville

Dune House Hotel and Spa

Dune House Hotel and Spa
4.5 star property
6.8 km from Isle of Palms South
8.8 out of 10, Excellent, (1,003 reviews)
"Great hotel!!…. Beautiful room overlooking the ocean!!!"
United States
David
The price is ฿8,070
฿10,521 total
includes taxes & fees
19 Mar - 20 Mar
Dune House Hotel and Spa

San Marco Inn East

San Marco Inn East
3.0 star property
19.5 km from Isle of Palms South
8.4 out of 10, Very good, (1,396 reviews)
"Probably nicest motel I've stayed at for the price!"
United States
Nelson
San Marco Inn East

Hampton Inn & Suites Jacksonville South - Bartram Park

Hampton Inn & Suites Jacksonville South - Bartram Park
3.0 star property
18.4 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,010 reviews)
"Clean room, good breakfast, friendly and helpful staff. It was my second time staying there, and there's a reason I came back. I'd happily stay there again, too."
United States
Nicolas
The price is ฿3,592
฿4,077 total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites Jacksonville South - Bartram Park

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
4.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (3,759 reviews)
"Yes room was spotless and staff was amazing!"
United States
Martina
The price is ฿5,388
฿6,115 total
includes taxes & fees
5 Apr - 6 Apr
Margaritaville Jacksonville Beach

Weekly Inn

Weekly Inn
2.0 star property
14.7 km from Isle of Palms South
7.6 out of 10, Good, (1,149 reviews)
"Room was clean no frills worth the money for a quick stay. "
United States
Deborah
Weekly Inn

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.8 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,012 reviews)
"Very friendly staff, good restaurants in hotel and in the complex "
United States
Richard
The price is ฿5,039
฿5,618 total
includes taxes & fees
5 Apr - 6 Apr
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms, 2 km from Isle of Palms South
9.4 out of 10, Exceptional, (469 reviews)
"Clean room, amazing staff great location "
United States
Darlene
The price is ฿5,163
฿5,860 total
includes taxes & fees
20 Mar - 21 Mar
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.7 km from Isle of Palms South
8.8 out of 10, Excellent, (1,018 reviews)
"Staff was nice and room was clean "
United States
Charles
The price is ฿3,833
฿4,350 total
includes taxes & fees
4 Apr - 5 Apr
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
9.7 km from Isle of Palms South
9.8 out of 10, Exceptional, (86 reviews)
"New, clean room and nice breakfast."
United States
Gregory
The price is ฿4,244
฿4,817 total
includes taxes & fees
5 Apr - 6 Apr
TownePlace Suites by Marriott® Jacksonville Mayport

Midtown Lodge

Midtown Lodge
2.5 star property
18.9 km from Isle of Palms South
8.2 out of 10, Very good, (608 reviews)
"Friendly staff good location"
United States
STEVE
Midtown Lodge

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.2 km from Isle of Palms South
9.2 out of 10, Wonderful, (295 reviews)
"The room was very clean, the staff very friendly, everything was great! "
United States
Starla
The price is ฿4,000
฿4,540 total
includes taxes & fees
29 Mar - 30 Mar
Home2 Suites By Hilton Jacksonville Downtown

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
4.6 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,017 reviews)
"Great location, breakfast was delicious "
United States
Paul
The price is ฿4,079
฿4,630 total
includes taxes & fees
22 Mar - 23 Mar
Best Western Oceanfront

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,041 reviews)
"Clean room, good breakfast and location"
United States
Jesus
The price is ฿4,156
฿4,717 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.1 km from Isle of Palms South
7.4 out of 10, Good, (413 reviews)
"The room was amazing"
United States
Stephen
The price is ฿2,316
฿2,628 total
includes taxes & fees
2 Apr - 3 Apr
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
5.2 km from Isle of Palms South
8.4 out of 10, Very good, (1,003 reviews)
"very clean room,friendly staff"
United States
john
The price is ฿6,176
฿7,010 total
includes taxes & fees
16 Mar - 17 Mar
Courtyard by Marriott Jacksonville Beach Oceanfront

Marriott Jacksonville Downtown

Marriott Jacksonville Downtown
4.0 star property
22.8 km from Isle of Palms South
8.4 out of 10, Very good, (1,012 reviews)
"Hotel is very clean. Stsff at front desk was very friendly and helpfull."
United States
Sharon
The price is ฿6,382
฿7,243 total
includes taxes & fees
3 Apr - 4 Apr
Marriott Jacksonville Downtown

The Hotel Palms

The Hotel Palms
3.5 star property
6.6 km from Isle of Palms South
9.6 out of 10, Exceptional, (294 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The price is ฿5,986
฿6,795 total
includes taxes & fees
2 Apr - 3 Apr
The Hotel Palms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms South

Find the best Isle of Palms South areas for the activities you enjoy most.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Top Isle of Palms South Hotel Reviews

Frequently asked questions

What is Isle of Palms South like?
Travellers will be sure to find plenty to entertain them in Jacksonville Beach's Isle of Palms South neighbourhood.
How many hotels can I expect to find in Isle of Palms South?
Expedia has 9 Isle of Palms South hotels and other accommodation options, and one might make a good home base for venturing out into the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms South, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view the best deals in Isle of Palms South.
What are the top things to see and do in Isle of Palms South?
Cradle Creek Preserve, Windsor Parke Golf Club and Jacksonville Beach Golf Club are just a few of the places to visit in and around Isle of Palms South. Windsor Commons Shopping Center and Harbor City Municipal Golf Course are also worth a visit when you're out sightseeing in Jacksonville Beach.