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3 Jul - 5 Jul
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10 Jul - 12 Jul

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Our top choices for Isle of Palms South hotels

41-inch Smart TV with cable channels

Weekly Inn

Weekly Inn
2.0 star property
14.7 km from Isle of Palms South
7.6 out of 10, Good, (1,344 reviews)
"We understand for one night but it is a very clean neat place"
United States
Ramon
The price is ฿1,724
฿1,957 total
includes taxes & fees
26 Jul - 27 Jul
Weekly Inn
Terrace/patio

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.2 km from Isle of Palms South
9.2 out of 10, Wonderful, (362 reviews)
"really enjoyed my stay at the hotel"
United States
Stacy
The price is ฿4,069
฿4,618 total
includes taxes & fees
19 Jul - 20 Jul
Home2 Suites By Hilton Jacksonville Downtown
Studio, One King Bed, Non-Smoking | Hypo-allergenic bedding, in-room safe, desk, laptop workspace

Hampton Inn Jacksonville-I-295 East/Baymeadows

Hampton Inn Jacksonville-I-295 East/Baymeadows
2.5 star property
9.9 km from Isle of Palms South
8.4 out of 10, Very good, (1,005 reviews)
"The staff were excellent, especially the desk clerk name Catelynn."
United States
Jerry
The price is ฿3,245
฿3,684 total
includes taxes & fees
12 Jul - 13 Jul
Hampton Inn Jacksonville-I-295 East/Baymeadows
Lobby

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Oceanfront, 4.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (4,094 reviews)
"Great room and very convenient location"
United States
Lyndi
The price is ฿5,561
฿6,312 total
includes taxes & fees
5 Jul - 6 Jul
Margaritaville Jacksonville Beach
Sports facility

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.5 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,077 reviews)
"Great stay!"
United States
William
The price is ฿4,231
฿4,802 total
includes taxes & fees
12 Jul - 13 Jul
Hyatt Place Jacksonville / St. Johns Town Center
Reception

Midtown Lodge

Midtown Lodge
2.5 star property
18.9 km from Isle of Palms South
8.0 out of 10, Very good, (689 reviews)
"Stay was great, I've stayed here multiple times and I would recommend this hotel for convenience to the highway, grocery store ( walmart, Aldi) and close to most places "
United States
Preston
The price is ฿2,155
฿2,446 total
includes taxes & fees
6 Jul - 7 Jul
Midtown Lodge
Premium bedding, desk, blackout curtains, iron/ironing board

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.1 km from Isle of Palms South
7.6 out of 10, Good, (533 reviews)
"The hotel was clean and staff was proficient."
United States
Maxine
The price is ฿2,429
฿2,757 total
includes taxes & fees
6 Jul - 7 Jul
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
Exterior

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.2 km from Isle of Palms South
8.8 out of 10, Excellent, (1,004 reviews)
"Nice staff and very clean"
United States
Amber
The price is ฿3,326
฿3,775 total
includes taxes & fees
12 Jul - 13 Jul
Holiday Inn Express Jacksonville - Blount Island by IHG
Free daily buffet breakfast

Wingate by Wyndham Jacksonville FL

Wingate by Wyndham Jacksonville FL
3.0 star property
15.2 km from Isle of Palms South
7.4 out of 10, Good, (1,009 reviews)
"Clean room great staff always were helpful nice breakfast excellent housekeepers"
United States
Steven
The price is ฿2,963
฿3,363 total
includes taxes & fees
1 Jul - 2 Jul
Wingate by Wyndham Jacksonville FL
On the beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
Oceanfront, 4.6 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,006 reviews)
"Great stay"
United States
Adam
The price is ฿5,055
฿5,738 total
includes taxes & fees
5 Jul - 6 Jul
Best Western Oceanfront
Exterior

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
8.7 km from Isle of Palms South
9.6 out of 10, Exceptional, (111 reviews)
"I really like this location and would definitely stay here again."
United States
Althia
The price is ฿4,114
฿4,669 total
includes taxes & fees
13 Jul - 14 Jul
Hyatt Studios Jacksonville/St Johns Town Center
Exterior

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
22.1 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,671 reviews)
"One of the best places I’ve stayed at. Great food and friendly staff."
United States
Cynthia
The price is ฿6,652
฿7,625 total
includes taxes & fees
8 Jul - 9 Jul
Hyatt Regency Jacksonville
Exterior

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,154 reviews)
"Great location not too far from beaches restsurants, and shopping."
United States
Donna L.
The price is ฿4,575
฿5,193 total
includes taxes & fees
5 Jul - 6 Jul
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Lounge

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
8.9 km from Isle of Palms South
9.4 out of 10, Exceptional, (213 reviews)
"Loved our stay"
United States
Jaime
The price is ฿5,953
฿6,757 total
includes taxes & fees
12 Jul - 13 Jul
AC Hotel Jacksonville St Johns Town Center
Exterior

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.8 km from Isle of Palms South
8.8 out of 10, Excellent, (722 reviews)
"We liked the hotel, it was a nice experience. We all had a good time."
United States
Shannon
The price is ฿5,063
฿6,502 total
includes taxes & fees
8 Jul - 9 Jul
Seahorse Oceanfront Inn
Standard Room, 2 Double Beds, Non Smoking | Individually furnished, laptop workspace, blackout curtains, free WiFi

Suburban Studios Orange Park - Jacksonville near Naval Air Station

Suburban Studios Orange Park - Jacksonville near Naval Air Station
2.0 star property
27.8 km from Isle of Palms South
7.4 out of 10, Good, (46 reviews)
"good place to stay last minute beds are really soft"
United States
tajuan
The price is ฿1,847
฿2,078 total
includes taxes & fees
28 Jul - 29 Jul
Suburban Studios Orange Park - Jacksonville near Naval Air Station
Property amenity

Days Inn by Wyndham Orange Park/Jacksonville

Days Inn by Wyndham Orange Park/Jacksonville
2.0 star property
27.6 km from Isle of Palms South
7.6 out of 10, Good, (1,005 reviews)
"I love the staff, especially Karen made my stay great"
United States
Matthew
The price is ฿2,205
฿2,481 total
includes taxes & fees
13 Jul - 14 Jul
Days Inn by Wyndham Orange Park/Jacksonville
Exterior

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
8.5 km from Isle of Palms South
9.6 out of 10, Exceptional, (1,002 reviews)
"Great place to stay"
United States
Clyde
The price is ฿4,257
฿4,832 total
includes taxes & fees
12 Jul - 13 Jul
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Lobby

Wyndham Garden Jacksonville

Wyndham Garden Jacksonville
3.0 star property
15.3 km from Isle of Palms South
8.0 out of 10, Very good, (1,924 reviews)
"I enjoyed the stay"
United States
Siddiq
The price is ฿2,664
฿3,024 total
includes taxes & fees
13 Jul - 14 Jul
Wyndham Garden Jacksonville
Property amenity

Fairfield Inn by Marriott Jacksonville Orange Park

Fairfield Inn by Marriott Jacksonville Orange Park
3.0 star property
27.9 km from Isle of Palms South
7.8 out of 10, Good, (754 reviews)
"Good"
United States
Wilfrid
The price is ฿2,370
฿2,666 total
includes taxes & fees
14 Jul - 15 Jul
Fairfield Inn by Marriott Jacksonville Orange Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Isle of Palms South

Find the best Isle of Palms South areas for the activities you enjoy most.
A coastal cityscape at dusk with a prominent clock tower, waterfront, and historic buildings.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Oceanfront

While visiting Oceanfront, you might make a stop by sights like Oceanfront Park and Northeast Florida Beaches.

A city skyline with modern skyscrapers, a prominent Wells Fargo building, and a blue bridge over a river.
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

A sunset over a beach with fallen trees and a distant shoreline.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

A golf course with a pond, trees, and buildings in the background.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Top Isle of Palms South Hotel Reviews

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center

10/10 Excellent
"We really enjoyed our stay at the Hyatt. The only issue we experienced was at the pool, there were no towels available, and after asking the front desk multiple times, no one ever brought any out. Aside from that, everything else was great. We had a wonderful experience overall and would definitely stay here again."
Brittney 4-night trip
Posted 2 hours ago
Hyatt Place Jacksonville / St. Johns Town Center

Frequently asked questions

What is Isle of Palms South like?
Travellers will be sure to find plenty to entertain them in Jacksonville Beach's Isle of Palms South neighbourhood.
How many hotels can I expect to find in Isle of Palms South?
Expedia has 7 Isle of Palms South hotels and other accommodation options, and one might make a good home base for venturing out into the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms South, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view the best deals in Isle of Palms South.
What are the top things to see and do in Isle of Palms South?
Cradle Creek Preserve, Windsor Parke Golf Club and Jacksonville Beach Golf Club are just a few of the places to visit in and around Isle of Palms South. Windsor Commons Shopping Center and Harbor City Municipal Golf Course are also worth a visit when you're out sightseeing in Jacksonville Beach.