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Our top choices for Isle of Palms hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (538 reviews)
"My family stayed here. Clean hotel and great breakfast."
United States
Ryan
The price is ฿5,336
฿6,056 total
includes taxes & fees
19 Jun - 20 Jun
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.3 km from Isle of Palms
7.6 out of 10, Good, (514 reviews)
"The hotel was clean and staff was proficient."
United States
Maxine
The price is ฿2,420
฿2,746 total
includes taxes & fees
17 Jun - 18 Jun
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

Wingate by Wyndham Jacksonville FL

Wingate by Wyndham Jacksonville FL
3.0 star property
15.4 km from Isle of Palms
7.4 out of 10, Good, (1,023 reviews)
"Clean room great staff always were helpful nice breakfast excellent housekeepers"
United States
Steven
The price is ฿2,332
฿2,647 total
includes taxes & fees
16 Jun - 17 Jun
Wingate by Wyndham Jacksonville FL

Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport
2.5 star property
30.8 km from Isle of Palms
9.0 out of 10, Wonderful, (463 reviews)
"Nice place to stay "
United States
Tanya
The price is ฿2,651
฿3,009 total
includes taxes & fees
19 Jun - 20 Jun
Extended Stay America Premier Suites - Jacksonville - Airport

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.6 km from Isle of Palms
8.8 out of 10, Excellent, (714 reviews)
"Fun if you want to be at the beach or just need a clean place to stay to enjoy the area."
United States
Margot
The price is ฿4,949
฿6,361 total
includes taxes & fees
17 Jun - 18 Jun
Seahorse Oceanfront Inn

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.4 km from Isle of Palms
9.2 out of 10, Wonderful, (349 reviews)
"really enjoyed my stay at the hotel"
United States
Stacy
The price is ฿3,999
฿4,539 total
includes taxes & fees
28 Jun - 29 Jun
Home2 Suites By Hilton Jacksonville Downtown

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
9.1 km from Isle of Palms
9.4 out of 10, Exceptional, (209 reviews)
"Great stay! Highly recommend and tons to do in the area."
United States
Adam
The price is ฿5,859
฿6,650 total
includes taxes & fees
18 Jun - 19 Jun
AC Hotel Jacksonville St Johns Town Center

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Oceanfront, 4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (4,075 reviews)
"Great room and very convenient location"
United States
Lyndi
The price is ฿5,473
฿6,212 total
includes taxes & fees
17 Jun - 18 Jun
Margaritaville Jacksonville Beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
Oceanfront, 4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1,004 reviews)
"Great stay"
United States
Adam
The price is ฿4,975
฿5,647 total
includes taxes & fees
5 Jul - 6 Jul
Best Western Oceanfront

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,138 reviews)
"Great location not too far from beaches restsurants, and shopping."
United States
Donna L.
The price is ฿4,338
฿4,923 total
includes taxes & fees
30 Jun - 1 Jul
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
2.1 km from Isle of Palms
9.4 out of 10, Exceptional, (253 reviews)
"Beautiful hotel!! It was extremely quiet and we all slept amazing!!"
United States
christine
The price is ฿5,342
฿6,063 total
includes taxes & fees
26 Jun - 27 Jun
Hilton Jacksonville At Mayo Clinic

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
8.9 km from Isle of Palms
9.6 out of 10, Exceptional, (85 reviews)
"I really like this location and would definitely stay here again."
United States
Althia
The price is ฿4,146
฿4,705 total
includes taxes & fees
23 Jun - 24 Jun
Hyatt Studios Jacksonville/St Johns Town Center

Weekly Inn

Weekly Inn
2.0 star property
14.9 km from Isle of Palms
7.6 out of 10, Good, (1,319 reviews)
"We understand for one night but it is a very clean neat place"
United States
Ramon
The price is ฿1,747
฿1,983 total
includes taxes & fees
29 Jun - 30 Jun
Weekly Inn

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,059 reviews)
"Location was very convenient"
United States
Thomas
The price is ฿4,164
฿4,726 total
includes taxes & fees
21 Jun - 22 Jun
Hyatt Place Jacksonville / St. Johns Town Center

Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
Oceanfront, 5 km from Isle of Palms
8.6 out of 10, Excellent, (1,003 reviews)
"Great location, great staff."
United States
Donna
The price is ฿5,663
฿6,427 total
includes taxes & fees
28 Jun - 29 Jun
Courtyard by Marriott Jacksonville Beach Oceanfront

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.3 km from Isle of Palms
8.8 out of 10, Excellent, (1,003 reviews)
"Nice staff and very clean"
United States
Amber
The price is ฿3,208
฿3,641 total
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Express Jacksonville - Blount Island by IHG

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,010 reviews)
"Very enjoyable stay!"
United States
Kristin
The price is ฿4,268
฿4,759 total
includes taxes & fees
28 Jun - 29 Jun
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Days Inn by Wyndham Jacksonville Airport

Days Inn by Wyndham Jacksonville Airport
2.5 star property
31.2 km from Isle of Palms
6.0 out of 10, (1,004 reviews)
"The room was clean with daily visits."
United States
Maxine
The price is ฿2,087
฿2,369 total
includes taxes & fees
16 Jun - 17 Jun
Days Inn by Wyndham Jacksonville Airport

Midtown Lodge

Midtown Lodge
2.5 star property
19.1 km from Isle of Palms
8.0 out of 10, Very good, (682 reviews)
"The rooms are nice and clean and it’s peaceful"
United States
Jerrica
The price is ฿1,856
฿2,106 total
includes taxes & fees
16 Jun - 17 Jun
Midtown Lodge

Hampton Inn Jacksonville-I-295 East/Baymeadows

Hampton Inn Jacksonville-I-295 East/Baymeadows
2.5 star property
10.1 km from Isle of Palms
8.4 out of 10, Very good, (1,010 reviews)
"The staff were excellent, especially the desk clerk name Catelynn."
United States
Jerry
The price is ฿3,194
฿3,625 total
includes taxes & fees
21 Jun - 22 Jun
Hampton Inn Jacksonville-I-295 East/Baymeadows
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms

Find the best Isle of Palms areas for the activities you enjoy most.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Top Isle of Palms Hotel Reviews

Frequently asked questions

What is Isle of Palms like?
Travellers are sure to enjoy a stay in Jacksonville Beach's Isle of Palms neighbourhood.
What's a favourite hotel to stay in Isle of Palms?
Based on our traveller data, Residence Inn By Marriott Jacksonville - Mayo Clinic Area is one of the top choices for your stay in Isle of Palms. This hotel offers free breakfast and an outdoor pool.
How many hotels should I expect to find in Isle of Palms?
Expedia has 38 hotels and other accommodation options in Isle of Palms to choose from, making this an ideal home base for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Isle of Palms.
What is there to do in this Jacksonville Beach neighbourhood?
A few places to visit in the area around Isle of Palms include Cradle Creek Preserve, Jacksonville Beach Golf Club and Windsor Parke Golf Club. While you're out sightseeing in Jacksonville Beach, make sure that you visit other sights such as Players by the Sea or Rhoda Martin Cultural Heritage Center.