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Our top choices for Isle of Palms hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (534 reviews)
"My family stayed here. Clean hotel and great breakfast."
United States
Ryan
The price is ฿5,367
฿6,091 total
includes taxes & fees
27 Jun - 28 Jun
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Wingate by Wyndham Jacksonville FL

Wingate by Wyndham Jacksonville FL
3.0 star property
15.4 km from Isle of Palms
7.4 out of 10, Good, (1,018 reviews)
"Clean room great staff always were helpful nice breakfast excellent housekeepers"
United States
Steven
The price is ฿2,341
฿2,657 total
includes taxes & fees
17 Jun - 18 Jun
Wingate by Wyndham Jacksonville FL

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.3 km from Isle of Palms
7.6 out of 10, Good, (505 reviews)
"Clean room , staff was great"
United States
Cameron
The price is ฿2,502
฿2,840 total
includes taxes & fees
11 Jun - 12 Jun
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.4 km from Isle of Palms
9.2 out of 10, Wonderful, (345 reviews)
"really enjoyed my stay at the hotel"
United States
Stacy
The price is ฿4,283
฿4,861 total
includes taxes & fees
5 Jul - 6 Jul
Home2 Suites By Hilton Jacksonville Downtown

Weekly Inn

Weekly Inn
2.0 star property
14.9 km from Isle of Palms
7.6 out of 10, Good, (1,311 reviews)
"We understand for one night but it is a very clean neat place"
United States
Ramon
The price is ฿1,600
฿1,816 total
includes taxes & fees
12 Jun - 13 Jun
Weekly Inn

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.6 km from Isle of Palms
8.8 out of 10, Excellent, (712 reviews)
"Fun if you want to be at the beach or just need a clean place to stay to enjoy the area."
United States
Margot
The price is ฿4,498
฿5,851 total
includes taxes & fees
16 Jun - 17 Jun
Seahorse Oceanfront Inn

Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport
2.5 star property
30.8 km from Isle of Palms
9.0 out of 10, Wonderful, (456 reviews)
"Nice place to stay "
United States
Tanya
The price is ฿2,667
฿3,026 total
includes taxes & fees
14 Jun - 15 Jun
Extended Stay America Premier Suites - Jacksonville - Airport

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
2.1 km from Isle of Palms
9.4 out of 10, Exceptional, (250 reviews)
"Beautiful hotel!! It was extremely quiet and we all slept amazing!!"
United States
christine
The price is ฿5,373
฿6,098 total
includes taxes & fees
3 Jul - 4 Jul
Hilton Jacksonville At Mayo Clinic

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
9.1 km from Isle of Palms
9.4 out of 10, Exceptional, (207 reviews)
"Great stay! Highly recommend and tons to do in the area."
United States
Adam
The price is ฿5,880
฿6,674 total
includes taxes & fees
19 Jun - 20 Jun
AC Hotel Jacksonville St Johns Town Center

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
Oceanfront, 4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1,002 reviews)
"Great stay"
United States
Adam
The price is ฿4,477
฿5,082 total
includes taxes & fees
15 Jun - 16 Jun
Best Western Oceanfront

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Oceanfront, 4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (4,053 reviews)
"Great property right on the beach, excellent views and food and plenty of spacious rooms"
United States
Lakesha
The price is ฿5,505
฿6,248 total
includes taxes & fees
14 Jun - 15 Jun
Margaritaville Jacksonville Beach

Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
Oceanfront, 5 km from Isle of Palms
8.6 out of 10, Excellent, (1,000 reviews)
"Hotel is great staff is great food at restaurant was great"
United States
robin
The price is ฿5,992
฿6,801 total
includes taxes & fees
29 Jun - 30 Jun
Courtyard by Marriott Jacksonville Beach Oceanfront

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,135 reviews)
"Great location not too far from beaches restsurants, and shopping."
United States
Donna L.
The price is ฿4,574
฿5,191 total
includes taxes & fees
28 Jun - 29 Jun
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Days Inn by Wyndham Jacksonville Airport

Days Inn by Wyndham Jacksonville Airport
2.5 star property
31.2 km from Isle of Palms
6.0 out of 10, (1,003 reviews)
"The room was clean with daily visits."
United States
Maxine
The price is ฿1,959
฿2,223 total
includes taxes & fees
11 Jun - 12 Jun
Days Inn by Wyndham Jacksonville Airport

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,056 reviews)
"Great stay!"
United States
William
The price is ฿4,188
฿4,753 total
includes taxes & fees
14 Jun - 15 Jun
Hyatt Place Jacksonville / St. Johns Town Center

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.3 km from Isle of Palms
8.8 out of 10, Excellent, (1,001 reviews)
"Nice staff and very clean"
United States
Amber
The price is ฿3,227
฿3,662 total
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Express Jacksonville - Blount Island by IHG

San Marco Inn East

San Marco Inn East
3.0 star property
19.7 km from Isle of Palms
8.6 out of 10, Excellent, (1,419 reviews)
"Excellent stay"
United States
shawn
The price is ฿2,160
฿2,452 total
includes taxes & fees
15 Jun - 16 Jun
San Marco Inn East

Rodeway Inn Orange Park - Jacksonville near Naval Air Station

Rodeway Inn Orange Park - Jacksonville near Naval Air Station
2.0 star property
27.9 km from Isle of Palms
7.8 out of 10, Good, (239 reviews)
"It was okay for the price"
United States
Dedrick
The price is ฿2,025
฿2,278 total
includes taxes & fees
5 Jul - 6 Jul
Rodeway Inn Orange Park - Jacksonville near Naval Air Station

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
8.9 km from Isle of Palms
9.6 out of 10, Exceptional, (77 reviews)
"Great staff, new hotel, a pleasure to stay in"
United States
Kevin
The price is ฿4,170
฿4,733 total
includes taxes & fees
14 Jun - 15 Jun
Hyatt Studios Jacksonville/St Johns Town Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms

Find the best Isle of Palms areas for the activities you enjoy most.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Top Isle of Palms Hotel Reviews

Frequently asked questions

What is Isle of Palms like?
Travellers are sure to enjoy a stay in Jacksonville Beach's Isle of Palms neighbourhood.
What's a favourite hotel to stay in Isle of Palms?
Based on our traveller data, Residence Inn By Marriott Jacksonville - Mayo Clinic Area is one of the top choices for your stay in Isle of Palms. This hotel offers free breakfast and an outdoor pool.
How many hotels should I expect to find in Isle of Palms?
Expedia has 38 hotels and other accommodation options in Isle of Palms to choose from, making this an ideal home base for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Isle of Palms.
What is there to do in this Jacksonville Beach neighbourhood?
A few places to visit in the area around Isle of Palms include Cradle Creek Preserve, Jacksonville Beach Golf Club and Windsor Parke Golf Club. While you're out sightseeing in Jacksonville Beach, make sure that you visit other sights such as Players by the Sea or Rhoda Martin Cultural Heritage Center.