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Our top choices for Isle of Palms hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (547 reviews)
"Great place to stay!"
United States
Chad
The price is ฿5,185
฿5,885 total
includes taxes & fees
19 Jul - 20 Jul
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.3 km from Isle of Palms
7.6 out of 10, Good, (528 reviews)
"The hotel was clean and staff was proficient."
United States
Maxine
The price is ฿2,430
฿2,758 total
includes taxes & fees
29 Jun - 30 Jun
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.4 km from Isle of Palms
9.2 out of 10, Wonderful, (359 reviews)
"really enjoyed my stay at the hotel"
United States
Stacy
The price is ฿4,087
฿4,639 total
includes taxes & fees
2 Jul - 3 Jul
Home2 Suites By Hilton Jacksonville Downtown

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.6 km from Isle of Palms
8.8 out of 10, Excellent, (720 reviews)
"We liked the hotel, it was a nice experience. We all had a good time."
United States
Shannon
The price is ฿5,093
฿6,540 total
includes taxes & fees
6 Jul - 7 Jul
Seahorse Oceanfront Inn

Wingate by Wyndham Jacksonville FL

Wingate by Wyndham Jacksonville FL
3.0 star property
15.4 km from Isle of Palms
7.4 out of 10, Good, (1,002 reviews)
"Clean room great staff always were helpful nice breakfast excellent housekeepers"
United States
Steven
The price is ฿2,258
฿2,563 total
includes taxes & fees
28 Jun - 29 Jun
Wingate by Wyndham Jacksonville FL

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
9.1 km from Isle of Palms
9.4 out of 10, Exceptional, (212 reviews)
"Loved our stay"
United States
Jaime
The price is ฿5,955
฿6,759 total
includes taxes & fees
26 Jun - 27 Jun
AC Hotel Jacksonville St Johns Town Center

Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport
2.5 star property
30.8 km from Isle of Palms
9.0 out of 10, Wonderful, (495 reviews)
"Excellent stay!"
United States
Amy
The price is ฿2,709
฿3,075 total
includes taxes & fees
28 Jun - 29 Jun
Extended Stay America Premier Suites - Jacksonville - Airport

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.3 km from Isle of Palms
8.8 out of 10, Excellent, (1,001 reviews)
"Nice staff and very clean"
United States
Amber
The price is ฿3,260
฿3,700 total
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Express Jacksonville - Blount Island by IHG

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
9.7 km from Isle of Palms
9.6 out of 10, Exceptional, (112 reviews)
"Great staff and breakfast!"
United States
Kandi
The price is ฿4,757
฿5,400 total
includes taxes & fees
1 Jul - 2 Jul
TownePlace Suites by Marriott® Jacksonville Mayport

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Oceanfront, 4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (4,061 reviews)
"Great room and very convenient location"
United States
Lyndi
The price is ฿5,593
฿6,348 total
includes taxes & fees
5 Jul - 6 Jul
Margaritaville Jacksonville Beach

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
8.9 km from Isle of Palms
9.6 out of 10, Exceptional, (102 reviews)
"I really like this location and would definitely stay here again."
United States
Althia
The price is ฿4,294
฿4,873 total
includes taxes & fees
17 Jul - 18 Jul
Hyatt Studios Jacksonville/St Johns Town Center

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
3 km from Isle of Palms
9.0 out of 10, Wonderful, (1,002 reviews)
"Nice clean easy stay. Staff interaction was all positive as well. Decent breakfast too."
United States
Heidi
The price is ฿3,792
฿4,304 total
includes taxes & fees
12 Jul - 13 Jul
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Tru by Hilton Jacksonville Airport I-95

Tru by Hilton Jacksonville Airport I-95
2.5 star property
31.5 km from Isle of Palms
9.4 out of 10, Exceptional, (1,116 reviews)
"Very clean, friendly staff and smelled good!!!"
United States
Niki
The price is ฿2,927
฿3,322 total
includes taxes & fees
12 Jul - 13 Jul
Tru by Hilton Jacksonville Airport I-95

Weekly Inn

Weekly Inn
2.0 star property
14.9 km from Isle of Palms
7.6 out of 10, Good, (1,334 reviews)
"We understand for one night but it is a very clean neat place"
United States
Ramon
The price is ฿1,796
฿2,039 total
includes taxes & fees
1 Jul - 2 Jul
Weekly Inn

Midtown Lodge

Midtown Lodge
2.5 star property
19.1 km from Isle of Palms
8.0 out of 10, Very good, (687 reviews)
"Stay was great, I've stayed here multiple times and I would recommend this hotel for convenience to the highway, grocery store ( walmart, Aldi) and close to most places "
United States
Preston
The price is ฿1,896
฿2,153 total
includes taxes & fees
30 Jun - 1 Jul
Midtown Lodge

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
2.1 km from Isle of Palms
9.4 out of 10, Exceptional, (264 reviews)
"Great hotel and very convenient to Mayo."
United States
Margaret
The price is ฿5,953
฿6,756 total
includes taxes & fees
24 Jul - 25 Jul
Hilton Jacksonville At Mayo Clinic

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,064 reviews)
"Great stay!"
United States
William
The price is ฿4,255
฿4,830 total
includes taxes & fees
28 Jun - 29 Jun
Hyatt Place Jacksonville / St. Johns Town Center

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
Oceanfront, 4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1,002 reviews)
"Great stay"
United States
Adam
The price is ฿4,817
฿5,467 total
includes taxes & fees
29 Jun - 30 Jun
Best Western Oceanfront

TownePlace Suites Jacksonville Airport

TownePlace Suites Jacksonville Airport
3.5 star property
31.6 km from Isle of Palms
9.6 out of 10, Exceptional, (368 reviews)
"The cleanest of the hotel was perfect and everything in general was perfect"
United States
Maria
The price is ฿4,458
฿5,060 total
includes taxes & fees
28 Jun - 29 Jun
TownePlace Suites Jacksonville Airport

Casa Marina Hotel

Casa Marina Hotel
3.0 star property
Oceanfront, 4.6 km from Isle of Palms
8.4 out of 10, Very good, (1,002 reviews)
"The dtaff was so friendly and helpful! The breakfast was great and the hotel was very clean. Just wish they had a pool or access to one with neighbor hotel."
United States
candy
The price is ฿4,215
฿4,784 total
includes taxes & fees
22 Jul - 23 Jul
Casa Marina Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms

Find the best Isle of Palms areas for the activities you enjoy most.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Oceanfront

While visiting Oceanfront, you might make a stop by sights like Oceanfront Park and Northeast Florida Beaches.

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Top Isle of Palms Hotel Reviews

Frequently asked questions

What is Isle of Palms like?
Travellers are sure to enjoy a stay in Jacksonville Beach's Isle of Palms neighbourhood.
What's a favourite hotel to stay in Isle of Palms?
Based on our traveller data, Residence Inn By Marriott Jacksonville - Mayo Clinic Area is one of the top choices for your stay in Isle of Palms. This hotel offers free breakfast and an outdoor pool.
How many hotels should I expect to find in Isle of Palms?
Expedia has 39 hotels and other accommodation options in Isle of Palms to choose from, making this an ideal home base for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Isle of Palms.
What is there to do in this Jacksonville Beach neighbourhood?
A few places to visit in the area around Isle of Palms include Cradle Creek Preserve, Jacksonville Beach Golf Club and Windsor Parke Golf Club. While you're out sightseeing in Jacksonville Beach, make sure that you visit other sights such as Players by the Sea or Rhoda Martin Cultural Heritage Center.