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Find hotels in Hartsville, SC from ฿1,943

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24 Dec - 25 Dec
Tomorrow
25 Dec - 26 Dec
This weekend
26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for Hartsville hotels

Reception
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville
2.5 star property
Hartsville
8.6 out of 10, Excellent, (679)
"very friendly older property but clean"
United States
Tamiko
The price is ฿2,618
฿2,932 total
includes taxes & fees
23 Jan - 24 Jan 2026
Fairfield Inn by Marriott Hartsville
Dining
Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville
2.5 star property
Hartsville
9.2 out of 10, Wonderful, (479)
"Staff was very friendly and accommodating!! Rooms were very clean! "
United States
Julia
The price is ฿3,801
฿4,257 total
includes taxes & fees
24 Jan - 25 Jan 2026
Hampton Inn & Suites Hartsville
Free daily continental breakfast
The Landmark Inn

The Landmark Inn

The Landmark Inn
2.5 star property
Hartsville
7.0 out of 10, Good, (315)
"Great staff"
United States
Thomas
The price is ฿2,240
฿2,617 total
includes taxes & fees
7 Jan - 8 Jan 2026
The Landmark Inn
Lobby
Quality Inn Hartsville

Quality Inn Hartsville

Quality Inn Hartsville
2.5 star property
Hartsville
6.0 out of 10, (329)
"Lady at desk was plesant and helpful. Sstart3ed to ask for our money back"
United States
Cynthia
The price is ฿1,913
฿2,164 total
includes taxes & fees
11 Jan - 12 Jan 2026
Quality Inn Hartsville
Rooftop terrace
The Mantissa Hotel

The Mantissa Hotel

The Mantissa Hotel
3.0 star property
Hartsville
9.2 out of 10, Wonderful, (270)
"Very nice spacious rooms friendly staff"
United States
Duane
The price is ฿5,042
฿5,647 total
includes taxes & fees
30 Dec - 31 Dec
The Mantissa Hotel
Lobby
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2504)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
The price is ฿1,933
฿2,165 total
includes taxes & fees
25 Dec - 26 Dec
Howard Johnson by Wyndham Florence
Lobby
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2202)
"Breakfast was great, room very clean ."
United States
Leann
The price is ฿2,633
฿2,949 total
includes taxes & fees
11 Jan - 12 Jan 2026
Park Inn by Radisson Florence, SC
Exterior
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1176)
"Great location, friendly staff. "
United States
Defelicio
The price is ฿3,019
฿3,381 total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn & Suites Florence Center Area
Terrace/patio
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
8.8 out of 10, Excellent, (1010)
"Great experience in a nice hotel in downtown."
United States
HATIM
The price is ฿3,111
฿3,484 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hyatt Place Florence Downtown
Exterior
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1004)
"Room was clean, staff was courteous and breakfast was great !"
United States
Angela
The price is ฿3,548
฿3,974 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Seasonal outdoor pool
Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

Super 8 by Wyndham Florence
2.0 star property
Florence
7.0 out of 10, Good, (1002)
"Clean room, Courteous Staff."
United States
Rhodney
The price is ฿1,720
฿1,926 total
includes taxes & fees
31 Dec - 1 Jan 2026
Super 8 by Wyndham Florence
Lobby
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
7.8 out of 10, Good, (1253)
"Room was spotless and the staff was friendly..."
United States
Randy
The price is ฿2,457
฿2,752 total
includes taxes & fees
12 Jan - 13 Jan 2026
Quality Inn & Suites Florence Civic Center
Terrace/patio
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very good, (1000)
"Hotel was clean , friendly staff"
United States
Gabriela
The price is ฿2,908
฿3,366 total
includes taxes & fees
30 Dec - 31 Dec
Tru by Hilton Florence I-95
Lobby
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
8.0 out of 10, Very good, (1677)
"Clean room & breakfast was good. Checkin staff was great, friendly and professional. "
United States
Cheryl
The price is ฿2,908
฿3,257 total
includes taxes & fees
28 Dec - 29 Dec
La Quinta Inn & Suites by Wyndham Florence
Restaurant
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (825)
"My go to stay while in Fairfax. "
United States
Gregory
The price is ฿3,037
฿3,402 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Florence Center
Front of property
Best Western Inn

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.6 out of 10, Good, (1010)
"Spotless room and courteous staff"
United States
Krusaundra
The price is ฿2,768
฿3,101 total
includes taxes & fees
25 Dec - 26 Dec
Best Western Inn
Exterior
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North
2.0 star property
Florence
6.8 out of 10, (1001)
"Clean room , quite area , walking distance "
United States
Gisell
The price is ฿1,824
฿2,043 total
includes taxes & fees
12 Jan - 13 Jan 2026
Days Inn by Wyndham Florence/I-95 North
Lobby sitting area
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
7.8 out of 10, Good, (28)
"Friendly staff and clean environment "
United States
john
The price is ฿2,909
฿3,382 total
includes taxes & fees
31 Dec - 1 Jan 2026
Spark by Hilton Florence North I-95, SC
Room, 1 Queen Bed, Accessible, Non Smoking | In-room safe, desk, iron/ironing board, free cots/infant beds
Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence
2.0 star property
Florence
6.8 out of 10, (1000)
"Good stay "
United States
Jimmy
The price is ฿1,836
฿2,057 total
includes taxes & fees
25 Dec - 26 Dec
Microtel Inn & Suites by Wyndham Florence
Lobby
Comfort Suites Florence I-95

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very good, (1000)
"Pool was clean good breakfast "
United States
Ann
The price is ฿3,193
฿3,701 total
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites Florence I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Hartsville attractions

Kalmia Gardens

4.0/5 (27 reviews)
Explore the great outdoors at Kalmia Gardens, a lovely green space in Hartsville. You'll find more to see and do in this walkable area.
See properties

Coker College

4.2/5 (59 reviews)
Explore the campus of Coker College during your trip to Hartsville. You'll find more to see and do in this walkable area.
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Learn more about Hartsville

Stroll along the scenic Black Creek, where kayakers glide past historic buildings and lush parks. Sonoco Park's trails and Kalmia Gardens' blooms offer peaceful retreats, while Coker University's campus adds a vibrant collegiate atmosphere to this charming Southern town.

See all hotels in Hartsville
The Midnight Rooster is my go to spot in my hometown of Hartsville, SC. Great brunch and coffee! Love the courtyard!
Photo by Caroline Nunez
Open Photo by Caroline Nunez

Top Hartsville Hotel Reviews

More cheap stays in Hartsville

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
The price is ฿1,933 per night from 25 Dec to 26 Dec
฿1,933
฿2,165 total
25 Dec - 26 Dec
includes taxes & fees
8.6/10 Excellent! (2,507 reviews)

Frequently asked questions

What's the best place to stay in Hartsville?
The Mantissa Hotel is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Reviews from our site also recommend Hampton Inn & Suites Hartsville and Fairfield Inn by Marriott Hartsville as top options for your trip. See all available top hotels, or vacation rentals in Hartsville.
If I need to cancel my hotel reservation in Hartsville, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Hartsville.
What's the best LGBTQ-friendly place to stay in Hartsville?
Fairfield Inn by Marriott Hartsville is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Hampton Inn & Suites Hartsville is another good option for your trip. See all available hotels listed as LGBTQ-friendly in Hartsville.
What's the best dog-friendly accommodation option in Hartsville?
Hampton Inn & Suites Hartsville is a top hotel for people travelling with their pets, and offers an outdoor pool and a fitness centre for its human guests. Two other good options for you and your pet include The Landmark Inn and Quality Inn Hartsville. See more pet-friendly hotel accommodations in Hartsville.
What are some accommodation options with pools in Hartsville?
Hampton Inn & Suites Hartsville is a top hotel with a pool, free buffet breakfast and free WiFi. View all hotels with pools in Hartsville.
What's the top hotel in Hartsville with an on-site water park or a water park nearby?
Quality Inn Hartsville is a popular hotel, featuring water park access, a seasonal outdoor pool and free parking. You'll find Neptune Island Waterpark within 5 minutes by car. Take a look at all hotels with or near waterparks in Hartsville.
How is it staying in Hartsville?
Visitors to Hartsville will definitely enjoy the restaurants. Tourists can also enjoy the city's university setting and shopping. In Hartsville, there are 19 hotels and other accommodation options to choose from. Find out more about Hartsville.
What is there to see in Hartsville?
Cultural venues include Hartsville Museum and Center Theatre. Landmarks like Kalmia Gardens and East Home Avenue Historic District might be worth a visit. The picturesque setting of Byerly Park and Segars-McKinnon Heritage Preserve exemplify the area's natural beauty. Take a look at what more there is to see and do in Expedia's Hartsville guide.
What's the seasonal weather like in Hartsville?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Hartsville is 1317 mm.