What's it like in East Side Pioneers?

Travellers are sure to enjoy a stay in Rochester's East Side Pioneers neighbourhood. Are you looking for East Side Pioneers travel tips? Make sure that you visit Mayo Civic Center and Rochester Art Center while you're in the neighbourhood.

What's the best accommodation in East Side Pioneers?

Based on our traveller data, Hotel Indigo Rochester – Mayo Clinic Area by IHG is one of the top choices for your stay in East Side Pioneers. This hotel is a short 7-minute walk from Mayo Clinic, and it offers a restaurant and a fitness centre. Other good options for your stay in the area include Hilton Rochester Mayo Clinic Area and Broadway Plaza, Trademark Collection by Wyndham .

How many hotels should I expect to find in East Side Pioneers?

If you're searching for places to stay in Rochester, Expedia has something to meet your needs with 22 East Side Pioneers hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in East Side Pioneers, will I receive a refund?

Yes! The majority of room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals in East Side Pioneers.

What can I see and do in this Rochester neighbourhood?

Spend some time exploring the natural setting of East Side Pioneers with a visit to Silver Lake Park and Mayo Park. You could also plan a visit to Mayo Civic Center or Rochester Art Center while you're in the neighbourhood. A few places to visit in the area around East Side Pioneers include Rochester Civic Theater, Rochester Public Library and Shops University Square. While you're out sightseeing, Plummer Building and Soldiers Field Veterans Memorial are a couple of additional sights to visit in Rochester.

The Best Hotels in East Side Pioneers, Rochester - 2026 Updated Prices

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Our top choices for East Side Pioneers hotels

A modern living room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a view of a cityscape through large windows.

1. Hilton Rochester Mayo Clinic Area

East Side Pioneers

Jennifer

฿6,596 total

includes taxes & fees

27 Nov - 28 Nov

A spacious outdoor dining area with multiple tables and chairs, large windows, and a wooden ceiling structure.

2. Hotel Indigo Rochester – Mayo Clinic Area by IHG

East Side Pioneers

Kathleen

฿3,784 total

includes taxes & fees

28 Nov - 29 Nov

A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

3. Broadway Plaza, Trademark Collection by Wyndham

East Side Pioneers

Jennifer

฿6,596 total

includes taxes & fees

27 Nov - 28 Nov

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

4. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester, 1.3 km from East Side Pioneers

Robert Blaise

฿4,336 total

includes taxes & fees

27 Nov - 28 Nov

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

5. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester, 1.1 km from East Side Pioneers

Richard

฿4,609 total

includes taxes & fees

11 Dec - 12 Dec

A modern building with large glass windows and indoor plants.

6. Marriott Rochester Mayo Clinic

Downtown Rochester, 1.2 km from East Side Pioneers

Christine

฿7,760 total

includes taxes & fees

27 Nov - 28 Nov

A coffee shop interior with a wooden counter, menu boards, and seating area.

7. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park, 1.7 km from East Side Pioneers

Neil

฿5,342 total

includes taxes & fees

27 Nov - 28 Nov

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

8. Brentwood Inn & Suites

Downtown Rochester, 1.5 km from East Side Pioneers

Anne

฿4,680 total

includes taxes & fees

15 Nov - 16 Nov

A swimming pool with a glass ceiling, a neon sign for the KAFFLER HOTEL, and a view of the city skyline at dusk.

9. Kahler Grand Hotel

Downtown Rochester, 1.3 km from East Side Pioneers

Jennifer

฿5,381 total

includes taxes & fees

15 Nov - 16 Nov

A poolside area with wicker chairs and potted plants, a tiled floor, and a clear view of the pool.

10. Kahler Inn and Suites - Mayo Clinic Area

Downtown Rochester, 1.4 km from East Side Pioneers

Laura

฿5,580 total

includes taxes & fees

27 Nov - 28 Nov

A garden with a water feature, rocks, and yellow umbrellas.

11. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest, 1.7 km from East Side Pioneers

Jordan

฿4,453 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel lobby with multiple seating areas, including a central dining table with chairs, a bar area, and a seating section with cushioned chairs.

12. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Kutzky Park, 2.4 km from East Side Pioneers

Jackie

฿4,352 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor terrace with tables and chairs, a large umbrella, and a view of a modern building with string lights.

13. Residence Inn by Marriott Rochester Mayo Clinic Area

Downtown Rochester, 1.5 km from East Side Pioneers

Keith

฿5,811 total

includes taxes & fees

27 Nov - 28 Nov

A modern living room with a fireplace, comfortable seating, and large windows.

14. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park, 2.3 km from East Side Pioneers

Sheri

฿4,162 total

includes taxes & fees

25 Nov - 26 Nov

A modern indoor patio with a fire feature, seating, and large windows.

15. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park, 2.3 km from East Side Pioneers

Ashley

฿4,903 total

includes taxes & fees

26 Nov - 27 Nov

An outdoor patio area with a concrete floor, wooden fence, and string lights.

16. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park, 3 km from East Side Pioneers

Brien

฿4,352 total

includes taxes & fees

26 Nov - 27 Nov

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

17. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Kutzky Park, 2.7 km from East Side Pioneers

Paul

฿4,276 total

includes taxes & fees

27 Nov - 28 Nov

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

18. The Berkman

Folwell, 2.8 km from East Side Pioneers

Suzette

฿7,105 total

includes taxes & fees

1 Dec - 2 Dec

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

19. Home2 Suites by Hilton Rochester Mayo Clinic Area

3.4 km from East Side Pioneers

howard

฿4,310 total

includes taxes & fees

13 Dec - 14 Dec

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

20. Hampton Inn Rochester-South

3.3 km from East Side Pioneers

Susan

฿3,780 total

includes taxes & fees

12 Dec - 13 Dec

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Compare popular hotels in East Side Pioneers

Property	Property class	Guest rating
Hilton Rochester Mayo Clinic Area	3.5 star property	9.6 Exceptional 657 reviews	View
Broadway Plaza, Trademark Collection by Wyndham	3.0 star property	9.2 Wonderful 189 reviews	View
Hotel Indigo Rochester – Mayo Clinic Area by IHG	3.5 star property	8.8 Excellent 1,001 reviews	View
TownePlace Suites by Marriott Rochester Mayo Clinic Area	3.0 star property	9.6 Exceptional 577 reviews	View
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	3.0 star property	9.6 Exceptional 755 reviews	View

Where to stay in East Side Pioneers

Find the best East Side Pioneers areas for the activities you enjoy most.

An aerial view of a cityscape with various buildings, including a prominent clock tower and several high-rise structures.

Downtown Rochester

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

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A calm river reflecting a bridge and buildings, surrounded by trees and a clear sky.

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Mayo Civic Center and Cascade Lake Beach.

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A cityscape with a river, a bridge, and various buildings including a large circular structure and a tall skyscraper.

Historic Southwest

While visiting Historic Southwest, you might make a stop by sights like Soldiers Field Veterans Memorial and Plummer House.

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A snowy forest path with leafless trees and a clear sky.

Slatterly Park

While Slatterly Park isn't home to many top sights, Mayo Civic Center and Olmsted County Fairgrounds are some notable places to visit nearby.

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A city skyline with a river reflecting buildings, trees lining the riverbank, and a sunset sky.

Northrup

When in Northrup, you can plan a visit to Mayo Civic Center and Rochester Recreation Center, some noteworthy sights in the nearby area.

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Top East Side Pioneers Hotel Reviews

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent

"Great hotel! Staff was friendly and helpful. Room was clean. Breakfast was good for a continental breakfast. Pool was GREAT! I would definitely stay here again. The only negative about the stay was the mattress. It had almost no support. Not sure if it needs to be replaced or if it's just put in its time, but a firmer mattress would be appreciated."