Find hotels in East Prairie, MO from ฿1,979

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24 Oct - 25 Oct
Tomorrow
25 Oct - 26 Oct
This weekend
24 Oct - 26 Oct
Next weekend
31 Oct - 2 Nov

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Top 10 East Prairie hotels and places to stay

1 bedroom, desk, laptop workspace, blackout curtains
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2.0 star property
7.2 out of 10, Good, (1002)
"Clean and comfortable "
United States
Jim
The price is ฿2,062
฿2,350 total
includes taxes & fees
3 Nov - 4 Nov
Days Inn and Suites by Wyndham Sikeston
Exterior
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 star property
8.8 out of 10, Excellent, (410)
"Nice property and friendly staff."
United States
Nancy
The price is ฿3,468
฿3,926 total
includes taxes & fees
2 Nov - 3 Nov
Hampton Inn Sikeston
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
8.6 out of 10, Excellent, (433)
"Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great."
United States
Kristen
The price is ฿3,311
฿3,749 total
includes taxes & fees
14 Nov - 15 Nov
Holiday Inn Express & Suites Sikeston Southwest by IHG
Free daily full breakfast
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 star property
8.4 out of 10, Very good, (1012)
"Very convenient and great breakfast "
United States
Duwaine
The price is ฿2,758
฿3,144 total
includes taxes & fees
9 Nov - 10 Nov
Best Western Plus Sikeston
Lobby
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, (1001)
"Wonderful place to stay"
United States
Carrie
The price is ฿2,524
฿2,901 total
includes taxes & fees
1 Nov - 2 Nov
Pear Tree Inn Sikeston
Hallway
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
8.4 out of 10, Very good, (696)
"Stayed one night. Good rate for the Hotel "
United States
Paul
The price is ฿1,983
฿2,260 total
includes taxes & fees
26 Oct - 27 Oct
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Front of property – evening/night
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
6.6 out of 10, (598)
"Tracey Allen checked me in. She was great!"
United States
Timothy
The price is ฿1,783
฿1,979 total
includes taxes & fees
30 Oct - 31 Oct
Super 8 by Wyndham Charleston/Sikeston East MO
Lobby
Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of America
2.5 star property
9.0 out of 10, Wonderful, (290)
"Great place and clean"
United States
Jim and Sarah
The price is ฿2,508
฿2,978 total
includes taxes & fees
9 Nov - 10 Nov
Sleep Inn at Discovery Park of America
Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi
Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
6.6 out of 10, (557)
"I enjoyed our stay"
United States
Alex
The price is ฿1,949
฿2,222 total
includes taxes & fees
26 Oct - 27 Oct
Super 8 by Wyndham Sikeston/Miner Area
Seasonal outdoor pool
Hospitality House Union City I 69 / US 51
Hospitality House Union City I 69 / US 51
2.5 star property
6.8 out of 10, (344)
"Great staff wonderful and professional demeanor. Will definitely stay again "
United States
Julius
The price is ฿1,785
฿2,120 total
includes taxes & fees
22 Nov - 23 Nov
Hospitality House Union City I 69 / US 51
Exterior
Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55
2.5 star property
8.4 out of 10, Very good, (273)
"The Jacuzzi was the Best!!! 👏"
United States
Shonta'
The price is ฿2,898
฿3,303 total
includes taxes & fees
30 Oct - 31 Oct
Comfort Inn & Suites Sikeston I-55
Property amenity
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, (1001)
"Very nice and quiet "
United States
Lana
The price is ฿2,950
฿3,392 total
includes taxes & fees
3 Nov - 4 Nov
Drury Inn & Suites Sikeston, MO
Lobby
Quality Inn Union City US 51
Quality Inn Union City US 51
2.5 star property
8.4 out of 10, Very good, (478)
"The Staff for sure is what keeps me coming back! Plus the rooms are very clean!"
United States
Walter
The price is ฿2,347
฿2,787 total
includes taxes & fees
9 Nov - 10 Nov
Quality Inn Union City US 51
Reception
Country Hearth Inn & Suites Union City
Country Hearth Inn & Suites Union City
2.5 star property
8.6 out of 10, Excellent, (542)
"Clean rooms, helpful and polite staff"
United States
Jennifer
The price is ฿2,360
฿2,803 total
includes taxes & fees
27 Oct - 28 Oct
Country Hearth Inn & Suites Union City
Bar (on property)
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
9.2 out of 10, Wonderful, (28)
"Very clean and comfortable room. "
United States
Roxanne
The price is ฿3,442
฿3,897 total
includes taxes & fees
14 Nov - 15 Nov
Fairfield Inn & Suites by Marriott Sikeston
Lobby
Quality Inn Cairo I-57
Quality Inn Cairo I-57
2.5 star property
6.6 out of 10, (271)
"Break fast was excellent "
United States
Uma
The price is ฿2,190
฿2,430 total
includes taxes & fees
31 Oct - 1 Nov
Quality Inn Cairo I-57
Terrace/patio
Hampton Inn Union City
Hampton Inn Union City
2.5 star property
9.4 out of 10, Exceptional, (156)
"Staff was very friendly, room was quiet, easy to get to. Room was clean and comfortable❤️"
United States
Diana
The price is ฿3,363
฿3,994 total
includes taxes & fees
23 Nov - 24 Nov
Hampton Inn Union City
Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets
New Orleans Inn Portageville
New Orleans Inn Portageville
2.5 star property
8.0 out of 10, Very good, (710)
"This is a hidden gem of a place. It is so peaceful and serene. Large clean rooms, hot showers, restaurant next door, cant ask for much more in life. All the staff were excellent as well. "
United States
Quincy
The price is ฿2,623
฿2,832 total
includes taxes & fees
22 Nov - 23 Nov
New Orleans Inn Portageville
Free daily buffet breakfast
Holiday Inn Express & Suites Union City by IHG
Holiday Inn Express & Suites Union City by IHG
2.5 star property
9.2 out of 10, Wonderful, (302)
"I really liked the hotel, it was also walking distance to our destination. "
United States
Devonda
The price is ฿3,475
฿4,127 total
includes taxes & fees
21 Nov - 22 Nov
Holiday Inn Express & Suites Union City by IHG
Gazebo
Travel Inn
Travel Inn
2.5 star property
5.8 out of 10, (112)
"Great place"
United States
Brian
Travel Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

10/10 Excellent
"Always have a great stay when I stay here, thank you. "
De'Tavis 2-night trip
Posted 5 days ago
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

More cheap stays in East Prairie

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr, Sikeston, MO
The price is ฿2,062 per night from 3 Nov to 4 Nov
฿2,062
฿2,350 total
3 Nov - 4 Nov
includes taxes & fees
7.2/10 Good! (1,008 reviews)

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Days Inn and Suites by Wyndham Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
How is it staying in East Prairie?
Visitors will definitely enjoy all that East Prairie has to offer. There are 31 hotels and other accommodation options in the surrounding area. Find out more about East Prairie.
What are the top places to visit in East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Central Park and Sikeston Depot Museum in the area. Take a look at what more there is to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.

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