Search Hotels in East Main Street, Grand Junction

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Check prices for these dates

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19 Dec - 20 Dec
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20 Dec - 21 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for East Main Street hotels

Lobby
Comfort Inn & Suites Fruita - Grand Junction

Comfort Inn & Suites Fruita - Grand Junction

Comfort Inn & Suites Fruita - Grand Junction
2.5 star property
18.5 km from East Main Street
8.4 out of 10, Very good, (1001)
"The location was convenient and the staff was friendly. "
United States
Charles
The price is ฿2,244
฿2,565 total
includes taxes & fees
28 Dec - 29 Dec
Comfort Inn & Suites Fruita - Grand Junction
Exterior
La Quinta Inn & Suites by Wyndham Fruita

La Quinta Inn & Suites by Wyndham Fruita

La Quinta Inn & Suites by Wyndham Fruita
3.0 star property
18.8 km from East Main Street
8.4 out of 10, Very good, (1001)
"Great breakfast and easy to walk to places next door "
United States
Amber
The price is ฿2,477
฿2,830 total
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Fruita
Modern Tiny Home on the Colo. River (9) | Individually decorated, free WiFi, bed sheets
Camp Eddy

Camp Eddy

Camp Eddy
1.0 star property
Pear Park, 1.5 km from East Main Street
9.4 out of 10, Exceptional, (292)
"Very clean tiny house, friendly management."
United States
Brian
The price is ฿1,924
฿3,828 total
includes taxes & fees
1 Jan - 2 Jan 2026
Camp Eddy
Lobby
Best Western Grande River Inn & Suites

Best Western Grande River Inn & Suites

Best Western Grande River Inn & Suites
2.5 star property
8.7 km from East Main Street
8.8 out of 10, Excellent, (793)
"Room and breakfast was typucal, ut bummed the pool and hot tub were closed."
United States
Phil
The price is ฿2,912
฿3,066 total
includes taxes & fees
28 Dec - 29 Dec
Best Western Grande River Inn & Suites
Free daily continental breakfast
Super 8 by Wyndham Fruita

Super 8 by Wyndham Fruita

Super 8 by Wyndham Fruita
2.0 star property
18.5 km from East Main Street
8.4 out of 10, Very good, (1002)
"Nice place with lots of food choices within a walkable block."
United States
Daniel
The price is ฿1,886
฿2,155 total
includes taxes & fees
22 Dec - 23 Dec
Super 8 by Wyndham Fruita
Indoor pool, open 7:00 AM to 10:00 PM, pool loungers
Home2 Suites by Hilton Grand Junction Northwest

Home2 Suites by Hilton Grand Junction Northwest

Home2 Suites by Hilton Grand Junction Northwest
3.0 star property
24 Road Corridor, 5.9 km from East Main Street
9.2 out of 10, Wonderful, (879)
"Great location, clean room, very pleasant staff "
United States
Allison
The price is ฿4,598
฿5,272 total
includes taxes & fees
25 Dec - 26 Dec
Home2 Suites by Hilton Grand Junction Northwest
House, 3 Bedrooms | Private kitchen | Fridge, oven, coffee/tea maker, electric kettle
Bark And Bike Abode 3 Bedroom Home

Bark And Bike Abode 3 Bedroom Home

Bark And Bike Abode 3 Bedroom Home
3.0 star property
17.3 km from East Main Street
The price is ฿5,692
฿16,907 total
includes taxes & fees
19 Jan - 20 Jan 2026
Bark And Bike Abode 3 Bedroom Home
Seasonal outdoor pool, pool umbrellas
Wine Country Inn Palisade

Wine Country Inn Palisade

Wine Country Inn Palisade
3.5 star property
17.1 km from East Main Street
9.6 out of 10, Exceptional, (1005)
"Everything about our stay was excellent and we will definitely stay there in the future."
United States
Bill
Wine Country Inn Palisade
View from property
SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.

SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.

SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.
3.5 star property
Historic Grand Junction, 1.5 km from East Main Street
9.0 out of 10, Wonderful, (1001)
"Very nice family hotel with good breakfast."
United States
Margarita
The price is ฿3,646
฿4,202 total
includes taxes & fees
28 Dec - 29 Dec
SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.
Restaurant
Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown
2.5 star property
Historic Grand Junction, 1.4 km from East Main Street
9.2 out of 10, Wonderful, (986)
"Very nice hotel and would choose it again"
United States
Billy
The price is ฿2,571
฿2,948 total
includes taxes & fees
7 Jan - 8 Jan 2026
Tru by Hilton Grand Junction Downtown
Interior detail
The Hotel Melrose

The Hotel Melrose

The Hotel Melrose
2.0 star property
Historic Grand Junction, 1.3 km from East Main Street
9.2 out of 10, Wonderful, (132)
"Love this little hotel!"
United States
Gregory
The price is ฿6,365
฿7,299 total
includes taxes & fees
20 Dec - 21 Dec
The Hotel Melrose
Terrace/patio
Hotel Maverick

Hotel Maverick

Hotel Maverick
4.0 star property
Capitol Hill, 1.6 km from East Main Street
9.6 out of 10, Exceptional, (1002)
"Excellent place to stay in Grand Junction. "
United States
Steve
Hotel Maverick
Deluxe Room, 1 King Bed | Desk, blackout curtains, iron/ironing board, free WiFi
Ville 718

Ville 718

Ville 718
2.5 star property
Horizon Drive District, 4.6 km from East Main Street
6.8 out of 10, (351)
"Very nice quiet place while traveling through town. "
United States
Shane
The price is ฿1,855
฿2,127 total
includes taxes & fees
20 Dec - 21 Dec
Ville 718
Lobby
Quality Inn Grand Junction near University

Quality Inn Grand Junction near University

Quality Inn Grand Junction near University
3.0 star property
Horizon Drive District, 4.9 km from East Main Street
8.6 out of 10, Excellent, (1000)
"Great staff."
United States
Manford
The price is ฿1,750
฿2,007 total
includes taxes & fees
30 Dec - 31 Dec
Quality Inn Grand Junction near University
Restaurant
Hampton Inn Grand Junction Downtown/Historic Main Street

Hampton Inn Grand Junction Downtown/Historic Main Street

Hampton Inn Grand Junction Downtown/Historic Main Street
2.5 star property
Historic Grand Junction, 1.5 km from East Main Street
8.8 out of 10, Excellent, (1000)
"Very clean, well managed, and a nice overall stay"
United States
Jeff
The price is ฿2,810
฿3,221 total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Grand Junction Downtown/Historic Main Street
Reception
Red Roof Inn Grand Junction

Red Roof Inn Grand Junction

Red Roof Inn Grand Junction
2.0 star property
9.2 km from East Main Street
7.0 out of 10, Good, (1007)
"Front desk was great! "
United States
Susette
The price is ฿1,635
฿1,874 total
includes taxes & fees
21 Dec - 22 Dec
Red Roof Inn Grand Junction
Lobby
Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado
2.0 star property
Horizon Drive District, 4.8 km from East Main Street
7.4 out of 10, Good, (1001)
"Great staff"
United States
Theresa
The price is ฿1,576
฿1,808 total
includes taxes & fees
26 Dec - 27 Dec
Super 8 by Wyndham Grand Junction Colorado
Indoor spa tub
Clarion Inn Grand Junction

Clarion Inn Grand Junction

Clarion Inn Grand Junction
2.5 star property
Horizon Drive District, 5.3 km from East Main Street
8.4 out of 10, Very good, (1701)
"Amazing place ro stay verry accomodateing"
United States
justin
The price is ฿2,263
฿2,595 total
includes taxes & fees
30 Dec - 31 Dec
Clarion Inn Grand Junction
View from property
Fairfield Inn & Suites by Marriott Grand Junction Downtown

Fairfield Inn & Suites by Marriott Grand Junction Downtown

Fairfield Inn & Suites by Marriott Grand Junction Downtown
2.5 star property
Historic Grand Junction, 1.5 km from East Main Street
8.8 out of 10, Excellent, (688)
"Steve was super friendly and accommodating at both check in and check out. "
United States
Morey
The price is ฿3,568
฿4,092 total
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn & Suites by Marriott Grand Junction Downtown
Exterior
Holiday Inn Express & Suites Grand Junction by IHG

Holiday Inn Express & Suites Grand Junction by IHG

Holiday Inn Express & Suites Grand Junction by IHG
2.5 star property
24 Road Corridor, 5.9 km from East Main Street
8.6 out of 10, Excellent, (1000)
"The room was great and the staff was very nice. "
United States
Clarissa
The price is ฿4,904
฿5,623 total
includes taxes & fees
20 Dec - 21 Dec
Holiday Inn Express & Suites Grand Junction by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in East Main Street

Find the best East Main Street areas for the activities you enjoy most.

Redlands

You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.

Downtown

Though Downtown may not have many top sights, you can venture to the surrounding area to see attractions like Western Colorado Botanical Gardens and Bananas Fun Park.

Pear Park

While visiting Pear Park, you might make a stop by sights like Colorado River and James M. Robb – Colorado River State Park.

Historic Grand Junction

Visitors highly recommend Historic Grand Junction for its abundant dining options, and you can make a stop by Museum of the West while you're in town.

Horizon Drive District

Horizon Drive District might not have many top sights, but Grand Junction Motor Speedway and Canyon View Park are two attractions nearby that you can check out.

Top East Main Street Hotel Reviews

Hotel Maverick

Hotel Maverick

10/10 Excellent
"Kind and attentive staff. Beautiful rooftop resterant and patio. "
Shea 1-night trip
Posted 4 days ago
Hotel Maverick

Frequently asked questions

What's it like in East Main Street?
Travellers will be sure to enjoy their time in Grand Junction's East Main Street neighbourhood.
How many hotels can I expect to find in the East Main Street area?
If you're searching for places to stay in Grand Junction, Expedia has something to meet your needs with 22 East Main Street hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in East Main Street, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to get the best deals in East Main Street.
What is there to do around this Grand Junction neighbourhood?
A few places to visit in the area around East Main Street include Museum of the West, Western Colorado Botanical Gardens and Elliott Tennis Center. While you're out sightseeing, Western Colorado Center for the Arts and Tennis Junction Indoor Center are a couple of additional sights to visit in Grand Junction.