Dona Ana Holiday Rentals, Las Cruces: Private House Rentals

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Our top choices for Dona Ana hotels

A modern breakfast bar with a coffee machine, cereal and fruit options, and a yogurt, eggs, and milk dispenser.

A large, modern building with a curved roof and large glass windows, likely a hotel or conference center.

A modern hotel lobby with a wooden ceiling, a seating area with a sofa and chairs, a small table with a computer, and a decorative wall with a map design.

A hotel room with a blue sofa, a wooden coffee table, two beds with white bedding, a headboard with a blue accent, a framed picture on the wall, and a window with a geometric blind.

1. Holiday Inn Express & Suites Las Cruces North by IHG

Las Cruces

Deanna

฿4,262

฿4,917 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with a fire pit, sofas, and chairs.

A modern lounge area with a sofa, chairs, and tables, featuring pendant lighting and large windows.

A modern hotel room with a wooden desk, a grey sofa, a small ottoman, a television, and a bed with a white headboard.

A modern hotel room with a large bed, a desk with a computer, a television, and a kitchenette.

2. Home2 Suites by Hilton Las Cruces

Las Cruces

Annette

฿4,184

฿4,829 total

includes taxes & fees

31 Oct - 1 Nov

A hotel lobby with a 'Connect & Print' service area, a fireplace, and a seating area with blue chairs.

A hallway with two refrigerated beverage dispensers stocked with various drinks and snacks.

A lobby with a stone wall, a fireplace, and blue chairs.

A reception desk with a wooden finish, a sign reading "Corner Market," and a display of snacks.

3. Fairfield Inn by Marriott Las Cruces

Las Cruces

Lola

฿4,345

฿5,129 total

includes taxes & fees

1 Nov - 2 Nov

A pool area with a hot tub, lounge chairs, and a lifeguard stand.

A hotel room with a blue accent wall, a sofa, a bed, a desk, and a mirror.

A modern lobby with a sofa set, a small table with a potted plant, and a patterned wall.

A hotel with a modern design, featuring a covered entrance and multiple floors.

4. Comfort Suites Las Cruces I-25 North

Las Cruces

Jessica

฿3,476

฿4,149 total

includes taxes & fees

1 Nov - 2 Nov

A multi-story building with a stone facade, a central entrance with a wooden archway, and a blue car parked in front.

An outdoor patio with stone pillars, green chairs, and a table.

A restaurant with a bar area, wooden chairs, a round table, and wall art.

A hotel lobby with multiple seating areas, including round tables and sofas, a bar area with a television, and a large window with curtains.

5. Staybridge Suites Las Cruces by IHG

Las Cruces

beatrice

฿3,738

฿4,323 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with wicker furniture, a barbecue grill, and a stone wall.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A pool area with blue chairs and a no diving sign.

A TownePlace Suites Marriott hotel with a stone facade, multiple windows, and a covered entrance.

6. Towneplace Suites by Marriott Las Cruces

Las Cruces

Salome

฿3,896

฿4,502 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a central dining area, multiple seating options, and a modern chandelier.

An indoor swimming pool with clear water, tiled edges, and a metal safety railing.

A lobby with teal armchairs, a coffee bar, and a dining area.

A hotel with a modern facade, multiple parking spaces, and a well-lit entrance.

7. Hampton Inn & Suites Las Cruces I-10

Las Cruces

Brandon

฿3,693

฿4,272 total

includes taxes & fees

1 Nov - 2 Nov

A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows allowing natural light.

A hotel room with a sofa, a dining table, a kitchen area with a microwave, refrigerator, and sink.

A spacious living area with a fireplace, comfortable seating, and a television.

8. Hampton Inn & Suites Las Cruces I-25

Las Cruces

Magdalena

฿3,965

฿4,580 total

includes taxes & fees

25 Oct - 26 Oct

A pool area with a fountain, palm trees, and outdoor seating.

A hallway with a tiled floor, a chandelier, potted plants, and a cross at the end.

A brick pathway lined with lush greenery and stone columns, leading to a covered area with a pergola.

A fountain with a lotus design in a pool, surrounded by a balustrade and palm trees.

9. Hotel Encanto de Las Cruces

Las Cruces

Marc

฿2,997

฿4,395 total

includes taxes & fees

1 Nov - 2 Nov

A vending machine, a refrigerator, and a display of travel brochures.

A coffee machine with a coffee cup and a sign above it that says "RISE & SHINE".

An indoor swimming pool with two lanes, safety railings, and clear signage including pool capacity and no diving allowed.

A hotel room with two beds, a refrigerator, a desk with a chair, a mirror, and a window with curtains.

10. Studio 6 – Las Cruces, NM - Telshor

Las Cruces

"It was convenient spot because of how close it was to were I needed to be but the room I stayed in wasn’t the best to say the least. Pillows had hair from other people as well as the bathroom. Floor was dirty with crumbs around. There was another persons back scrubber towel hanging in the bathroom. Left the hotel at 2am because I couldn’t sleep, it sounded like an air compressor was going off for 2 seconds every 3-5 min and that went on all night. I was there for the night and just needed some...

Josue

฿1,980

฿2,329 total

includes taxes & fees

7 Oct - 8 Oct

A lobby with a stone fireplace, sofas, and a glass coffee table.

A courtyard with outdoor seating, a small tree, and a stone wall.

A spacious indoor dining area with high ceilings, large windows, and a variety of seating options including tables and booths.

A living room with a sofa, ottoman, TV, and a desk with a chair. There is a kitchen in the background.

11. Drury Inn & Suites Las Cruces

Las Cruces

Heather

฿3,570

฿4,132 total

includes taxes & fees

18 Oct - 19 Oct

A motel with a large '6' sign, indoor pool, spa, and suites.

A Coca-Cola vending machine, an exit sign, and a tiled floor in a building.

A hotel room with two beds, a desk, and a chair.

A swimming pool with a tiled edge, a lifeguard chair, and a sign indicating a 5ft depth.

12. Motel 6 Las Cruces, NM - Telshor

Las Cruces

Armando

฿1,864

฿2,198 total

includes taxes & fees

13 Oct - 14 Oct

A hotel room with two beds, a desk with a TV, a chair, and two lamps.

A multi-story hotel with a central entrance, balconies, and a parking area.

A living room with striped sofas, a glass coffee table, a fireplace, and a television.

13. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

Las Cruces

Kathy

฿2,001

฿2,353 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a large bed, two bedside lamps, a desk with a chair, a window with curtains, and a cityscape painting on the wall.

A hotel with a stone facade, a covered entrance, and a parking lot.

A dining area with multiple tables and chairs, a kitchen area with a refrigerator and a coffee machine, and a television mounted on the wall.

A hotel lobby with a reception desk, seating area, and a ceiling fan.

14. Super 8 by Wyndham Las Cruces/White Sands Area

Las Cruces

Leanne

฿1,718

฿2,032 total

includes taxes & fees

6 Nov - 7 Nov

A hotel room with a bed, a TV mounted on the wall, a desk, and a sofa.

A small, modern kitchenette with a white countertop, a sink, and a compact refrigerator.

A pool area with lounge chairs and umbrellas, surrounded by a fence and a building with multiple windows and balconies.

A modern hotel with a flat roof, large windows, and a well-lit entrance.

15. Springhill Suites By Marriott Las Cruces

Las Cruces

Verona R.

฿3,745

฿4,331 total

includes taxes & fees

13 Oct - 14 Oct

A buffet area with a variety of baked goods, a coffee station, and a decorative plant.

A patio with a table and chairs, a large tree, a fountain, and a pool in the background.

A cozy living room with a wooden sofa and armchair, a wooden coffee table, and a patterned rug.

16. Best Western Mission Inn

Las Cruces

John

฿2,688

฿3,132 total

includes taxes & fees

12 Oct - 13 Oct

A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.

A covered outdoor area with a patio, seating, and a small lawn.

A hotel dining area with multiple tables and chairs, a coffee station, and a reception desk.

A hotel room with a large bed, a television, a desk, and a chair.

17. Comfort Inn & Suites Las Cruces Mesilla

Las Cruces

Carlos

฿3,398

฿3,938 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with seating arrangements, including sofas and chairs, under a covered structure with a wooden ceiling.

A modern hotel lobby with a large sofa, armchairs, a coffee table, and a TV.

A Courtyard by Marriott hotel with a modern facade, multiple windows, and a covered entrance area.

A modern coffee shop interior with a wooden counter, seating area, and menu boards.

18. Courtyard by Marriott Las Cruces at NMSU

Las Cruces

Linda

฿5,104

฿5,872 total

includes taxes & fees

25 Oct - 26 Oct

A spacious hotel lobby with a modern design, featuring a reception desk, seating area, and potted plants.

A hotel room with a bed, a sofa, a desk, and a TV. There are framed pictures on the wall.

A hotel room with a large bed, a desk, a chair, a flat-screen TV, and a window with curtains.

An indoor swimming pool with clear water, a diving board, and lounge chairs.

19. Comfort Suites University Las Cruces

Las Cruces

Becky Ann

฿2,802

฿3,262 total

includes taxes & fees

1 Nov - 2 Nov

A spacious indoor courtyard with tiled flooring, wooden furniture, and a balcony with a railing.

An indoor swimming pool with tiled flooring, a metal pool ladder, and a few lounge chairs.

A lobby with a tiled floor, a staircase, and a patterned wall hanging.

A dining area with a table and chairs, a remote control on a rug, and a door leading to another room.

20. Ramada Hotel & Conference Center by Wyndham Las Cruces

Las Cruces

Felipe

฿2,567

฿2,987 total

includes taxes & fees

12 Oct - 13 Oct

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Top Dona Ana Hotel Reviews

Motel 6 Las Cruces, NM - Telshor

8/10 Good

"Staff was helpful."

Drury Inn & Suites Las Cruces

10/10 Excellent

"We had a 2 day Birthday weekend getaway and stayed in a King Suite at the Drury Inn. The rooms were bigger than any other Drury Inn we had ever encountered. They also had a separate wet bar area with a huge refrigerator, microwave, and coffee maker. The bed and pillows were extremely comfortable. Everything was clean and modernly appointed. The breakfast was extensive and their coffee was bikd and deliscious. They also have a happy hour in the late afternoon. Both included in the price. The staff, from front desk to breakfast area was always very friendly and attentive. The location is close to everything Mesilla has to offer. We would definitely stay here again, if and when in the area."

Hampton Inn & Suites Las Cruces I-10

10/10 Excellent

"Clean rooms"

Best Western Mission Inn

10/10 Excellent

"Clean room, and easy check in and out. The staff was polite, and the property is safe. Dog friendly, and a good spot if you are stopping in for a night."

Days Inn by Wyndham Las Cruces

8/10 Good

"Vcj"

Super 8 by Wyndham Las Cruces/White Sands Area

10/10 Excellent

"My son and his friends stayed here for 2 nights and they said it was great. I loved that fact that they let 19 year old's stay here, it's hard to find some place that lets some one stay that's under 21. Thank you Super 8 for taking care of my son and his friends!"

Staybridge Suites Las Cruces by IHG

8/10 Good

"Much better than my expectations. Very clean overall. The only complaint i have is the powdered/packaged scrambled eggs in the morning :( which is very common at hotels in USA lately.. But they have a decent breakfast.. Overall very satisfied.."

More cheap stays in Dona Ana

Days Inn by Wyndham Las Cruces

755 Avenida De Mesilla Las Cruces NM

฿1,660

฿1,967 total

1 Nov - 2 Nov

includes taxes & fees

8.2/10 Very good! (1,647 reviews)

Motel 6 Las Cruces, NM - Telshor

2120 Summit Ct Las Cruces NM

฿1,864

฿2,198 total

13 Oct - 14 Oct

includes taxes & fees

7.2/10 Good! (1,009 reviews)

Sleep Inn University

2121 S Triviz Dr Las Cruces NM

฿2,345

฿2,735 total

6 Nov - 7 Nov

includes taxes & fees

Best Western Mission Inn

1765 S Main St Las Cruces NM

฿2,688

฿3,132 total

12 Oct - 13 Oct

includes taxes & fees

8.8/10 Excellent! (1,253 reviews)

Comfort Suites University Las Cruces

2101 S Triviz Drive Las Cruces NM

฿2,802

฿3,262 total

1 Nov - 2 Nov

includes taxes & fees

Comfort Suites Las Cruces I-25 North

236 N Telshor Blvd. Las Cruces NM

฿3,476

฿4,149 total

1 Nov - 2 Nov

includes taxes & fees

Frequently asked questions

What's the best place to stay in Dona Ana?

Located 7.1 mi (11.4 km) from the heart of Dona Ana, Hotel Encanto de Las Cruces is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Ramada Hotel & Conference Center by Wyndham Las Cruces and La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain. See all available top hotels, or vacation rentals in Dona Ana.

If I need to cancel my hotel reservation in Dona Ana, will I receive a refund?

Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Dona Ana.

What is staying in Dona Ana like?

Those travelling to Dona Ana will definitely enjoy the sights to see and things to do. There are 369 hotels and other accommodation options in the surrounding area. Find out more about Dona Ana.

What are the top places to visit in Dona Ana?

Places to visit in the wider area include Sonoma Ranch Golf Course, Mesilla Valley Mall and Mesillia Plaza. You'll also find New Mexico Farm and Ranch Heritage Museum and Pan American Center in the area. Take a look at what more there is to see and do in Expedia's Dona Ana guide.

What's the seasonal weather like in Dona Ana?

The hottest months are usually June and July, with an average temperature of 28°C, while the coldest months are January and December, with an average of 9°C. Average annual precipitation for Dona Ana is 229 mm.

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Book Hotels in Dona Ana on Expedia.com

Find hotels in Dona Ana, NM from ฿1,967

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Dona Ana

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Dona Ana hotels

1. Holiday Inn Express & Suites Las Cruces North by IHG

2. Home2 Suites by Hilton Las Cruces

3. Fairfield Inn by Marriott Las Cruces

4. Comfort Suites Las Cruces I-25 North

5. Staybridge Suites Las Cruces by IHG

6. Towneplace Suites by Marriott Las Cruces

7. Hampton Inn & Suites Las Cruces I-10

8. Hampton Inn & Suites Las Cruces I-25

9. Hotel Encanto de Las Cruces

10. Studio 6 – Las Cruces, NM - Telshor

11. Drury Inn & Suites Las Cruces

12. Motel 6 Las Cruces, NM - Telshor

13. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

14. Super 8 by Wyndham Las Cruces/White Sands Area

15. Springhill Suites By Marriott Las Cruces

16. Best Western Mission Inn

17. Comfort Inn & Suites Las Cruces Mesilla

18. Courtyard by Marriott Las Cruces at NMSU

19. Comfort Suites University Las Cruces

20. Ramada Hotel & Conference Center by Wyndham Las Cruces

Top Dona Ana Hotel Reviews

Motel 6 Las Cruces, NM - Telshor

Drury Inn & Suites Las Cruces

Hampton Inn & Suites Las Cruces I-10

Best Western Mission Inn

Days Inn by Wyndham Las Cruces

Super 8 by Wyndham Las Cruces/White Sands Area

Staybridge Suites Las Cruces by IHG

More cheap stays in Dona Ana

Days Inn by Wyndham Las Cruces

Motel 6 Las Cruces, NM - Telshor

Sleep Inn University

Best Western Mission Inn

Comfort Suites University Las Cruces

Comfort Suites Las Cruces I-25 North

Frequently asked questions

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