Find hotels in Dona Ana, NM from ฿1,772

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Our top choices for Dona Ana hotels

Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1000)
In Las Cruces, this hotel offers free breakfast, WiFi, and parking near Luna Rossa Winery. Take a morning swim in the indoor pool, work out at the fitness centre, and experience the clean rooms and helpful staff praised by guests.

"Clean, great staff, comfortable rooms. "
United States
Lizette
The price is ฿2,780
฿3,230 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn & Suites Las Cruces I-10

Courtyard by Marriott Las Cruces at NMSU

Courtyard by Marriott Las Cruces at NMSU
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (508)
Located near New Mexico State University, this hotel offers an outdoor pool and The Bistro restaurant for breakfast and dinner. Enjoy the 24-hour fitness centre and bar after exploring nearby American Southwest Theatre Company and Pan American Centre.

"A very nice, clean, and convenient hotel. The food there was good too. I would stay there again."
United States
Perry
The price is ฿4,077
฿4,701 total
includes taxes & fees
17 Jan - 18 Jan 2026
Courtyard by Marriott Las Cruces at NMSU

Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North
2.5 star property
Las Cruces
9.2 out of 10, Wonderful, (1000)
Experience Las Cruces with a splash in the indoor pool, relaxing hot tub, and rejuvenating spa services at this welcoming hotel. Enjoy free breakfast, WiFi, and parking while being close to Mesilla Valley Mall and Sonoma Ranch Golf Course.

"Hotel was very festive, clean and great customer service "
United States
Vanessa
The price is ฿3,413
฿4,062 total
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites Las Cruces I-25 North

Holiday Inn Express & Suites Las Cruces North by IHG

Holiday Inn Express & Suites Las Cruces North by IHG
2.5 star property
Las Cruces
9.0 out of 10, Wonderful, (981)
Located in Las Cruces, this hotel features an indoor pool and hot tub for year-round relaxation. Clean rooms include refrigerators and microwaves. Enjoy free breakfast, WiFi, and parking while being close to Branigan Cultural Centre and local attractions.

"Breakfast was great."
United States
Ruben
The price is ฿3,677
฿4,247 total
includes taxes & fees
25 Dec - 26 Dec
Holiday Inn Express & Suites Las Cruces North by IHG

Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1001)
This business-friendly Las Cruces hotel offers a refreshing indoor pool, hot tub, and fitness centre. Each room includes a refrigerator and microwave. Luna Rossa Winery and Rio Grande Vineyards are nearby, with free breakfast, WiFi, and parking.

"Comfy convenient to Melilla plaza. "
United States
Dora
The price is ฿3,081
฿3,572 total
includes taxes & fees
30 Dec - 31 Dec
Comfort Inn & Suites Las Cruces Mesilla

Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25
2.5 star property
Las Cruces
8.4 out of 10, Very good, (1001)
"Room and service were great"
United States
Shaun
The price is ฿2,782
฿3,232 total
includes taxes & fees
30 Dec - 31 Dec
Hampton Inn & Suites Las Cruces I-25

Sleep Inn University

Sleep Inn University
2.5 star property
Las Cruces
7.6 out of 10, Good, (1000)
Experience tranquil comfort at this Las Cruces hotel with an indoor pool. Business-friendly amenities include free WiFi, buffet breakfast and parking. Close to Pan American Centre and Aggie Memorial Stadium, it's praised for clean rooms and helpful staff.

"Staff was very friendly and helpful, room was comfortable and clean."
United States
Krystal
The price is ฿1,825
฿2,142 total
includes taxes & fees
18 Jan - 19 Jan 2026
Sleep Inn University

Home2 Suites by Hilton Las Cruces

Home2 Suites by Hilton Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (662)
Enjoy morning workouts in the 24-hour fitness centre before exploring Sonoma Ranch Golf Course and Branigan Cultural Centre. Clean rooms await your return, with free breakfast, WiFi and parking enhancing your comfortable stay.

"We had a great stay! Staff were super friendly. Clean and comfortable rooms "
United States
Jessica
The price is ฿3,837
฿4,429 total
includes taxes & fees
28 Dec - 29 Dec
Home2 Suites by Hilton Las Cruces

Comfort Suites University Las Cruces

Comfort Suites University Las Cruces
2.5 star property
Las Cruces
8.0 out of 10, Very good, (1006)
Adjacent to a golf course, this Las Cruces hotel offers a peaceful atmosphere praised by travellers. The indoor pool provides morning refreshment while the fitness centre keeps workouts on track. Located in a safe area close to Aggie Memorial Stadium with free breakfast, WiFi, and parking.

"Amazing staff, clean rooms, great breakfast "
United States
Michelle
The price is ฿2,434
฿2,838 total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Suites University Las Cruces

Towneplace Suites by Marriott Las Cruces

Towneplace Suites by Marriott Las Cruces
3.0 star property
Las Cruces
8.6 out of 10, Excellent, (144)
Discover this hotel with outdoor pool and hot tub near Sonoma Ranch Golf Course. Take advantage of free breakfast, WiFi, and parking. The fitness centre and snack bar add convenience while sofa beds offer extra sleeping space.

"Loved the suite with Full Kitchen! We also enjoyed the breakfast buffet and the pool!"
United States
LAURIE
The price is ฿3,411
฿3,945 total
includes taxes & fees
6 Jan - 7 Jan 2026
Towneplace Suites by Marriott Las Cruces

Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (1000)
Experience comfort at this Las Cruces hotel near Aggie Memorial Stadium and Pan American Centre. Enjoy Great American Grille's breakfast and dinner, relax in the hot tub, or maintain your routine in the 24-hour fitness centre. Clean rooms include refrigerators and microwaves.

"Staff was amazing place was good "
United States
cayetano
The price is ฿2,860
฿3,321 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hilton Garden Inn Las Cruces

Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
3.5 star property
Las Cruces
9.0 out of 10, Wonderful, (1603)
Experience serene relaxation at this historical hotel featuring an outdoor pool with stunning sunset mountain vistas. Enjoy authentic Mexican cuisine at Gardunos, unwind at one of 3 bars, and easily access nearby Mesilla Valley Mall.

"Very friendly and accommodating staff, room spotless and well appointed, food options, beautiful grounds"
United States
Therese H
The price is ฿3,492
฿4,881 total
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Encanto de Las Cruces

Springhill Suites By Marriott Las Cruces

Springhill Suites By Marriott Las Cruces
3.0 star property
Las Cruces
8.4 out of 10, Very good, (960)
Escape to this quiet hotel with a 24-hour fitness centre, outdoor pool, and hot tub. Near local restaurants, shops, and wineries like Luna Rossa and Rio Grande. Enjoy free breakfast, WiFi, and parking while business-ready rooms include sofa beds and refrigerators.

"Would stay again."
United States
Randy
The price is ฿2,893
฿3,358 total
includes taxes & fees
6 Jan - 7 Jan 2026
Springhill Suites By Marriott Las Cruces

Holiday Inn Express Hotel and Suites Las Cruces by IHG

Holiday Inn Express Hotel and Suites Las Cruces by IHG
2.5 star property
Las Cruces
7.8 out of 10, Good, (1000)
Located near American Southwest Theatre Company and Luna Rossa Winery, this hotel offers free breakfast, WiFi, and parking. Guests love the helpful staff and clean rooms. Convenient amenities include a rejuvenating indoor pool for year-round swimming.

"Great place to stay. "
United States
Martin and Nancy
The price is ฿3,453
฿3,982 total
includes taxes & fees
6 Jan - 7 Jan 2026
Holiday Inn Express Hotel and Suites Las Cruces by IHG

Studio 6 – Las Cruces, NM - Telshor

Studio 6 – Las Cruces, NM - Telshor
2.0 star property
Las Cruces
6.8 out of 10, (126)
Unwind at this comfortable Las Cruces motel featuring an indoor pool for morning swims and a hot tub for evening relaxation. With free WiFi and parking, you're just minutes from Sonoma Ranch Golf Course and Branigan Cultural Centre.

"Clean room, friendly & helpful front desk clerk, hot tub bery nice"
United States
Michael
The price is ฿1,804
฿2,124 total
includes taxes & fees
6 Jan - 7 Jan 2026
Studio 6 – Las Cruces, NM - Telshor

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (1001)
This business-friendly hotel offers a relaxing indoor pool and hot tub. Wake up to free breakfast, then drive to nearby attractions like Luna Rossa Winery and Rio Grande Vineyards. Guests consistently praise the helpful staff and convenient free parking.

"Clean room, good breakfast, nice staff, and great pricing. "
United States
Shahzad
The price is ฿2,924
฿3,393 total
includes taxes & fees
6 Jan - 7 Jan 2026
Drury Inn & Suites Las Cruces

Las Cruces Home w/ Fenced Yard: Recently Remodeled

Las Cruces Home w/ Fenced Yard: Recently Remodeled
3.0 star property
Las Cruces
Cosy Las Cruces accommodation with a welcoming patio and well-equipped kitchen for your Southwest adventure. Near local theatres and offering free parking, this air-conditioned cottage provides a comfortable home base.
The price is ฿3,235
฿8,168 total
includes taxes & fees
24 Jan - 25 Jan 2026
Las Cruces Home w/ Fenced Yard: Recently Remodeled

Fairfield Inn by Marriott Las Cruces

Fairfield Inn by Marriott Las Cruces
2.5 star property
Las Cruces
8.6 out of 10, Excellent, (510)
Unwind in Las Cruces with a refreshing morning swim in the outdoor pool and complimentary breakfast to start your day. This hotel offers free parking and a 24-hour fitness centre, all within 10 minutes of New Mexico State University and local attractions.

"Really good breakfast and helpful staff"
United States
Magdalena
The price is ฿3,675
฿4,245 total
includes taxes & fees
6 Jan - 7 Jan 2026
Fairfield Inn by Marriott Las Cruces

Desert Haven Cozy 2-Bedroom Mobile Home Near NMSU 2 Home

Desert Haven Cozy 2-Bedroom Mobile Home Near NMSU 2 Home
3.0 star property
Las Cruces
Smart holiday home with free WiFi, near American Southwest Theatre Company. Enjoy the in-room coffeemaker before exploring nearby hiking trails. Pan American Centre is close by, with Las Cruces International Airport just 16 minutes away.
The price is ฿4,067
฿12,446 total
includes taxes & fees
5 Jan - 6 Jan 2026
Desert Haven Cozy 2-Bedroom Mobile Home Near NMSU 2 Home

Best Western Mission Inn

Best Western Mission Inn
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1230)
Located in Las Cruces, this quiet hotel offers comfortable beds and a relaxing outdoor pool. Start each day with a complimentary buffet breakfast, and enjoy free parking. Helpful staff and nearby restaurants enhance the experience, all minutes from NMSU.

"Very comfortable place to stay"
United States
Maryann
The price is ฿2,380
฿2,776 total
includes taxes & fees
1 Jan - 2 Jan 2026
Best Western Mission Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Dona Ana Hotel Reviews

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Frequently asked questions

What's the best place to stay in Dona Ana?
Located 7.1 mi (11.4 km) from the heart of Dona Ana, Hotel Encanto de Las Cruces is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces. See all available top hotels, or vacation rentals in Dona Ana.
If I need to cancel my hotel reservation in Dona Ana, will I receive a refund?
Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Dona Ana.
What is staying in Dona Ana like?
Those travelling to Dona Ana will definitely enjoy the sights to see and things to do. There are 376 hotels and other accommodation options in the surrounding area. Find out more about Dona Ana.
What are the top places to visit in Dona Ana?
Places to visit in the wider area include Red Hawk Golf Club, Sonoma Ranch Golf Course and Las Cruces Museum of Art. You'll also find Mesilla Valley Mall and Mesillia Plaza in the area. Take a look at what more there is to see and do in Expedia's Dona Ana guide.
What's the seasonal weather like in Dona Ana?
The hottest months are usually June and July, with an average temperature of 28°C, while the coldest months are January and December, with an average of 9°C. Average annual precipitation for Dona Ana is 229 mm.

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