The Best Hotels Closest to Don and Sybil Harrington Cancer Center in Amarillo - 2026 Updated Prices

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Our top choices for Don and Sybil Harrington Cancer Center hotels

A spacious lobby with a modern design, featuring a seating area with colorful cushions, a large chandelier, and a flat-screen TV mounted on the wall.

A vending area with snack and drink options, including a refrigerated section with beverages and a shelf stocked with various snacks.

An indoor swimming pool with clear water, a tiled floor, and a ceiling with recessed lighting.

1. Best Western Plus Medical Center

0.4 km from Don and Sybil Harrington Cancer Center

Elizabeth

฿3,080

฿3,541 total

includes taxes & fees

27 Sept - 28 Sept

A spacious restaurant with high ceilings, stone walls, and large windows.

An indoor swimming pool with clear poolside areas, safety signs, and seating arrangements.

A hotel room with two beds, each with a headboard, bedside lamps, and a patterned throw blanket.

A multi-story hotel with a prominent entrance, multiple balconies, and a clear blue sky.

2. Drury Inn & Suites Amarillo

1.9 km from Don and Sybil Harrington Cancer Center

Randall

฿3,589

฿4,128 total

includes taxes & fees

27 Sept - 28 Sept

A modern room with a sofa, a chair, a lamp, and a television.

A modern hotel dining area with multiple tables and chairs, a large TV screen, and a central pillar with a geometric design.

A hotel room with a bed, a sofa, a desk with a chair, a TV, and a framed picture on the wall.

A modern lobby with seating areas, a reception desk, and a decorative tree centerpiece.

3. Holiday Inn Express & Suites Amarillo West by IHG

1.4 km from Don and Sybil Harrington Cancer Center

Jeannie

฿3,357

฿3,861 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio with a fire feature, seating, and a grill area.

A modern kitchen with a central island, a red waffle sign, and a coffee station.

A hotel hallway with a patterned carpet, white doors, and recessed lighting.

A modern hotel with a clear entrance, a covered waiting area, and a sign indicating a 15' clearance.

4. Hampton Inn & Suites Amarillo West

1.7 km from Don and Sybil Harrington Cancer Center

Miguel

฿3,434

฿3,949 total

includes taxes & fees

18 Oct - 19 Oct

A multi-story hotel with a modern design, featuring a prominent entrance and a parking lot.

A modern hotel lobby with a dining area, a reception desk, and a seating area with a coffee table.

A rooftop patio with outdoor seating, stone walls, and large windows.

An indoor swimming pool with lounge chairs and a view of the night sky through large windows.

5. Hyatt Place Amarillo-West

2.2 km from Don and Sybil Harrington Cancer Center

Vanessa

฿3,552

฿4,156 total

includes taxes & fees

4 Oct - 5 Oct

A modern lounge area with seating, tables, and a kitchen area.

A gym with treadmills, exercise balls, and weightlifting equipment.

A pool table in a room with a mural, seating, and a large window.

A modern food service area with a central counter, a refrigerated display, and various food items.

6. Tru By Hilton Amarillo West

2.1 km from Don and Sybil Harrington Cancer Center

Cory

฿2,775

฿3,213 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor seating area with a fire pit, lounge chairs, and a building with large windows and a covered patio.

A swimming pool with clear blue water, a diving board, and a seating area with chairs and tables.

A modern hotel room with a kitchenette, a bed, a desk, and a large window.

A multi-story hotel with a modern design, featuring a prominent entrance with outdoor seating and a covered area.

7. TownePlace Suites by Marriott Amarillo West/Medical Center

1.2 km from Don and Sybil Harrington Cancer Center

angela

฿5,631

฿6,476 total

includes taxes & fees

27 Sept - 28 Sept

An outdoor seating area with stone flooring, cushioned benches, and green chairs.

A hotel room with a bed, desk, and seating area.

A modern hotel lobby with a seating area, a bar, and a dining space.

A modern bar area with seating, a bar counter, and a television mounted on the ceiling.

8. Springhill Suites by Marriott Amarillo

1.6 km from Don and Sybil Harrington Cancer Center

Michael

฿4,066

฿4,676 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with two beds, a TV, a window with blinds, a framed picture on the wall, and a bedside lamp.

A multi-story hotel with a prominent 'My Place' sign, a parking lot, and a well-lit facade.

A modern kitchen with a black microwave, coffee maker, and a refrigerator.

9. My Place Hotel - Amarillo West/ Medical Center, TX

1.6 km from Don and Sybil Harrington Cancer Center

justin

฿3,201

฿3,681 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio with a stone fireplace, a grill, and a dining area with chairs and tables.

A hotel with a modern design, featuring a covered entrance, outdoor seating, and a well-maintained landscape.

A hotel lobby with a reception desk, seating area, and a large window with a view.

A spacious lobby with a fireplace, seating area, and a bar.

10. Homewood Suites by Hilton Amarillo

2.2 km from Don and Sybil Harrington Cancer Center

todd

฿2,966

฿3,411 total

includes taxes & fees

4 Oct - 5 Oct

A swimming pool with clear water, a brick deck, and a waterfall feature.

A hotel breakfast area with a self-service station, coffee makers, and various food containers.

A traditional living room with leather sofas, a fireplace, and a clock on the wall.

A hotel room with two beds, a desk with a computer, a chair, and a window with curtains.

11. Country Inn & Suites by Radisson, Amarillo I-40 West, TX

2 km from Don and Sybil Harrington Cancer Center

Gary

฿2,702

฿3,107 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor seating area with wicker chairs and a fire pit.

A sign instructing to clean up after dogs and dispose of waste, with a trash can nearby.

A multi-story hotel with a prominent 'Home2' sign, a covered entrance, and a parking lot.

A hotel room with a bed, a sofa, a desk, and a television.

12. Home2 Suites by Hilton Amarillo

1.3 km from Don and Sybil Harrington Cancer Center

Amanda

฿3,983

฿4,580 total

includes taxes & fees

18 Oct - 19 Oct

A lobby with a reception desk, seating area, and a stone wall with framed pictures.

A hotel lobby with a reception desk, a sofa, a dining area, and a kitchen.

A hotel room with a sofa, a bed, a desk, and a television.

13. Comfort Inn & Suites Amarillo West Near Medical Center

2.2 km from Don and Sybil Harrington Cancer Center

Alvin

฿2,962

฿3,406 total

includes taxes & fees

28 Sept - 29 Sept

A hotel lobby with a blue sofa, a fireplace, a dining area, and a TV mounted on the wall.

A Fairfield Inn & Suites Marriott hotel with a modern design, featuring a large parking lot and well-maintained landscaping.

A reception desk with a wooden finish, a black countertop, and a blue illuminated wall feature.

A modern living room with a fireplace, a blue sectional sofa, and a flat-screen TV mounted on the wall.

14. Fairfield Inn & Suites Amarillo West/Medical Center

1 km from Don and Sybil Harrington Cancer Center

Tania

฿2,969

฿3,482 total

includes taxes & fees

27 Sept - 28 Sept

A modern living room with a blue sofa, wooden flooring, and framed pictures on the walls.

A modern hotel with multiple floors, a parking lot, and a well-lit entrance.

A modern dining area with a wooden table and chairs, a television on a wall, and a view of the outside.

An outdoor patio area with stone walls, seating, and string lights.

15. Everhome Suites Amarillo West - Medical Center

1.2 km from Don and Sybil Harrington Cancer Center

Mohammad

฿3,221

฿3,704 total

includes taxes & fees

15 Oct - 16 Oct

A hotel lobby with a high ceiling, a fireplace, a flat-screen TV, and a large abstract painting on the wall.

A hotel room with a large bed, two bedside lamps, a wooden headboard, a nightstand, and a vase with flowers.

An outdoor patio area with tables and chairs, blue umbrellas, and a building labeled "Residence Inn" in the background.

A hotel room with a dining area, a fireplace, a TV, and a bed.

16. Yellow City Studios

1 km from Don and Sybil Harrington Cancer Center

Ayvan

฿1,915

฿2,202 total

includes taxes & fees

18 Oct - 19 Oct

A spacious living area with a large sofa, a fireplace, and a patterned floor.

A spacious kitchen with a large island, wooden cabinetry, and a minibar area.

A hotel with a large parking lot, a covered entrance, and a prominent American flag.

An indoor swimming pool with a tiled floor, ceiling fans, and a seating area with tables and chairs.

17. Hilton Garden Inn Amarillo

2.4 km from Don and Sybil Harrington Cancer Center

Gregory

฿2,797

฿3,217 total

includes taxes & fees

10 Oct - 11 Oct

An outdoor seating area with a fire feature, surrounded by modern buildings.

A modern bar area with a wooden counter, bar stools, a refrigerator stocked with beverages, and a menu board.

A modern kitchen with a bar area, a round dining table, and a sofa.

A modern living room with a stone wall, a fireplace, and a large sectional sofa.

18. Courtyard by Marriott Amarillo West/Medical Center

1.4 km from Don and Sybil Harrington Cancer Center

Ronnie

฿4,073

฿4,709 total

includes taxes & fees

28 Sept - 29 Sept

A spacious indoor area with wooden flooring, multiple seating arrangements including sofas and tables, and large windows allowing natural light.

A modern interior with a yellow counter, coffee machines, and a rocking chair.

A hotel room with two beds, a headboard, wall art, a lamp, and a window with curtains.

A modern interior with a green carpet, wooden flooring, and a wall with a geometric design.

19. Spark by Hilton Amarillo Medical Center

1.1 km from Don and Sybil Harrington Cancer Center

MICHAEL

฿2,430

฿2,795 total

includes taxes & fees

4 Oct - 5 Oct

A hotel entrance with a glass door, stone pillars, and a clear view of the parking lot.

A hotel reception area with a reception desk, a large mirror, and a patterned floor.

A buffet setup with multiple serving stations, including a toaster and a grill, against a tiled backsplash.

A pool area with two pools, one rectangular and one octagonal, with depth markers and a diving sign.

20. Sleep Inn & Suites West Medical Center

1.1 km from Don and Sybil Harrington Cancer Center

Lina

฿2,563

฿2,947 total

includes taxes & fees

18 Oct - 19 Oct

View all properties

Compare popular hotels close to Don and Sybil Harrington Cancer Center

Property	Property class	Guest rating
Best Western Plus Medical Center	9.4 Exceptional 1,912 reviews	View
Drury Inn & Suites Amarillo	9.4 Exceptional 2,476 reviews	View
Holiday Inn Express & Suites Amarillo West by IHG	9.4 Exceptional 2,304 reviews	View
Hampton Inn & Suites Amarillo West	9.4 Exceptional 515 reviews	View
Hyatt Place Amarillo-West	9.2 Wonderful 1,345 reviews	View

Top Don and Sybil Harrington Cancer Center Hotel Reviews

The Cactus Cove Inn and Suites

10/10 Excellent

"Friendly staff and great breakfast"

Holiday Inn Express & Suites Amarillo West by IHG

8/10 Good

"Good amenities"

Atrea Inn Amarillo

10/10 Excellent

"Really liked the easy check in process, cleanliness of the room, location, the breakfast and courtyard. Would definitely recommend and would stay here again."

Comfort Inn & Suites Amarillo West Near Medical Center

8/10 Good

"-"

Drury Inn & Suites Amarillo

10/10 Excellent

"The staff were all very friendly and helpful. The room was clean spacious. The breakfast and happy hour were both delightful."

Spark by Hilton Amarillo Western Plaza

8/10 Good

"Just what we wanted....clean, inexpensive, and comfortable."

Fifth Season Suites

8/10 Good

"A nice place. As I was checking in I asked about the pool and was told that it was open but there was a chain & lock on it. Later, I saw some people in the pool and wonder if it was employees. I asked if there was a handicap room or at least first floor. We were assigned a room on first floor but as far from the front as could be. After lugging our things way down there, I found out that we could have parked in the back close to a door near our room. I wish the woman checking me in would have mentioned that, especially since I'd mentioned handicap. And she watched me walk by with everything. It was shift change time and the person taking her place was very helpful. If it wasn't for this woman, I would have given it 5 stars all around."

Days Inn by Wyndham Amarillo - Medical Center

10/10 Excellent

"Got in very late. Bed was tough which I was happy for. Usually bed is overused at a hotel. I appreciated it being hard. Toilets seats didn't stay in on their own in any place i used the bathroom. Didn't like that."

Red Roof Inn Amarillo West

10/10 Excellent

"I drive from CO to TX regularly and have stayed at a lot of road-side hotels on the route. I usually travel with dogs and bikes, which require a large, pet friendly room. This was the largest and nicest room, in the value space, with a reasonable pet-fee, that I've stayed at in several years, and will become my spot to-stop on the route moving forward. The only thing that could use improvement, was the coffee/breakfast situation - but again, what was there was serviceable. We look forward to staying there again in the future!"

Frequently asked questions

What's the area like around Don and Sybil Harrington Cancer Center?

Don and Sybil Harrington Cancer Center is located in a family-friendly area of Amarillo known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 44 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Don and Sybil Harrington Cancer Center?

Holiday Inn Express & Suites Amarillo West by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.9 mi (1.4 km) from Don and Sybil Harrington Cancer Center. Other good options within a short distance include Spark by Hilton Amarillo Medical Center and Red Roof Inn Amarillo West.

How many hotels should I expect to find near Don and Sybil Harrington Cancer Center?

Expedia has 44 hotels and other accommodation options within a mile from Don and Sybil Harrington Cancer Center.

If I need to cancel the hotel reservation for my stay near Don and Sybil Harrington Cancer Center, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to get the best deals near Don and Sybil Harrington Cancer Center.

What can I see and do near Don and Sybil Harrington Cancer Center?

Don Harrington Discovery Center, Amarillo Museum of Art and Amarillo Art Center feature captivating exhibits. Learn about local history at Historic 6th Street Sign and Harrington House. You can enjoy live performances at Amarillo Little Theatre and Globe-News Center.

Search Hotels Near Don and Sybil Harrington Cancer Center, Amarillo

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Our top choices for Don and Sybil Harrington Cancer Center hotels

1. Best Western Plus Medical Center

2. Drury Inn & Suites Amarillo

3. Holiday Inn Express & Suites Amarillo West by IHG

4. Hampton Inn & Suites Amarillo West

5. Hyatt Place Amarillo-West

6. Tru By Hilton Amarillo West

7. TownePlace Suites by Marriott Amarillo West/Medical Center

8. Springhill Suites by Marriott Amarillo

9. My Place Hotel - Amarillo West/ Medical Center, TX

10. Homewood Suites by Hilton Amarillo

11. Country Inn & Suites by Radisson, Amarillo I-40 West, TX

12. Home2 Suites by Hilton Amarillo

13. Comfort Inn & Suites Amarillo West Near Medical Center

14. Fairfield Inn & Suites Amarillo West/Medical Center

15. Everhome Suites Amarillo West - Medical Center

16. Yellow City Studios

17. Hilton Garden Inn Amarillo

18. Courtyard by Marriott Amarillo West/Medical Center

19. Spark by Hilton Amarillo Medical Center

20. Sleep Inn & Suites West Medical Center

Compare popular hotels close to Don and Sybil Harrington Cancer Center

Top Don and Sybil Harrington Cancer Center Hotel Reviews

The Cactus Cove Inn and Suites

Holiday Inn Express & Suites Amarillo West by IHG

Atrea Inn Amarillo

Comfort Inn & Suites Amarillo West Near Medical Center

Drury Inn & Suites Amarillo

Spark by Hilton Amarillo Western Plaza

Fifth Season Suites

Days Inn by Wyndham Amarillo - Medical Center

Red Roof Inn Amarillo West

Frequently asked questions