A coastal cityscape with a prominent Ferris wheel, beachfront, and high-rise buildings.

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Check availability on South Carolina Business Hotels

This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for South Carolina business-friendly hotels

A covered outdoor area with a stone facade, a bench, and a truck parked nearby.

1. Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall
2.5 star property
Greenville
8.2 out of 10, Very good, (1,008 reviews)
"It's our second time here. We love that the location is very accessible to the mall, downtown area and restaurants."
United States
Maia
The price is ฿2,869
฿3,257 total
includes taxes & fees
11 Oct - 12 Oct
Comfort Inn Greenville - Haywood Mall
A modern hotel with a glass facade, a covered entrance, and a clear sky.

2. Hyatt Place Charleston Airport/Convention Center

Hyatt Place Charleston Airport/Convention Center
3.0 star property
North Charleston
9.4 out of 10, Exceptional, (1,269 reviews)
"Great place to stay"
United States
Gabriel
The price is ฿3,691
฿4,376 total
includes taxes & fees
12 Oct - 13 Oct
Hyatt Place Charleston Airport/Convention Center
A rooftop bar with tables and chairs, overlooking a cityscape at dusk.

3. Sheraton Columbia Downtown Hotel

Sheraton Columbia Downtown Hotel
3.5 star property
Downtown Columbia
8.4 out of 10, Very good, (1,003 reviews)
"Great service!"
United States
Bobby
The price is ฿3,826
฿4,285 total
includes taxes & fees
22 Oct - 23 Oct
Sheraton Columbia Downtown Hotel
A hotel with a curved facade, large windows, and a central tower.

4. Town & Country Inn and Suites

Town & Country Inn and Suites
3.0 star property
West Ashley
9.2 out of 10, Wonderful, (1,148 reviews)
"Great location and the room was very comfortable and clean. We will certainly choose this property again!"
United States
Barbara
The price is ฿5,000
฿5,700 total
includes taxes & fees
6 Oct - 7 Oct
Town & Country Inn and Suites
A spacious living area with a staircase, a sofa, a coffee table, and a desk with a chair.

5. Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente
2.5 star property
Greenville
8.0 out of 10, Very good, (1,001 reviews)
"The staff was very helpful and friendly. They were able to answer all of my questions since this was my first time staying there. The breakfast was great! Way more options than I was actually expecting and everything was cooked perfectly."
United States
Chris
The price is ฿2,204
฿2,497 total
includes taxes & fees
1 Nov - 2 Nov
Sleep Inn at Greenville Convention Cente
A hotel with a prominent tower, a covered entrance, and a well-lit facade.

6. La Quinta by Wyndham Haywood Mall-Near Greenville Downtown

La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
3.0 star property
Greenville
7.4 out of 10, Good, (1,132 reviews)
"Great place to stay for the pricing."
United States
James
The price is ฿2,282
฿2,510 total
includes taxes & fees
11 Oct - 12 Oct
La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
An outdoor patio with seating, a fire pit, string lights, and a grill area.

7. Home2 Suites by Hilton Greenville Downtown

Home2 Suites by Hilton Greenville Downtown
3.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1,002 reviews)
"Great staff, great location, great rooms!"
United States
Sylvia
The price is ฿4,651
฿5,116 total
includes taxes & fees
11 Oct - 12 Oct
Home2 Suites by Hilton Greenville Downtown
A modern lobby with a seating area, a large abstract painting, and a staircase.

8. Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood
3.0 star property
Greenville
8.0 out of 10, Very good, (1,004 reviews)
"Great hotel"
United States
Jonathan
The price is ฿2,819
฿3,194 total
includes taxes & fees
19 Oct - 20 Oct
Hyatt Place Greenville/Haywood
A resort with a large pool, palm trees, and a view of the ocean.

9. Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island
4.0 star property
South End
8.8 out of 10, Excellent, (1,533 reviews)
"This is our 5th visit, excellent place to stay"
United States
Scott
The price is ฿5,604
฿7,752 total
includes taxes & fees
1 Nov - 2 Nov
Sonesta Resort Hilton Head Island
A hotel room with two beds, a desk with a computer, a chair, and a view of the outdoors.

10. Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest
2.5 star property
Seven Oaks
5.6 out of 10, (1,000 reviews)
"So dirty place, never come back"
United States
Asmaa
The price is ฿1,782
฿1,925 total
includes taxes & fees
7 Oct - 8 Oct
Baymont by Wyndham Columbia Northwest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Carolina Hotel Reviews

Caribbean Resort & Villas

Caribbean Resort & Villas

10/10 Excellent
"I loved everything with this resort and want to do monthly rental from Nov 1 2026 to March 1 2027 can I get price and book"
Barbara 7-night trip
Posted less than an hour ago
Caribbean Resort & Villas

Frequently asked questions

How much do business-friendly hotels in South Carolina cost?
Prepare to pay between ฿1,925 and ฿7,752 per night for business-friendly hotels in South Carolina. Terrific deals on properties that cater to corporate travellers are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in South Carolina?
There are multiple business-friendly hotels in South Carolina with a total average guest review rating of 8.2, so you're sure to find the perfect place for you. Planning a trip to Myrtle Beach? Hilton Grand Holidays Club Ocean 22 Myrtle Beach is popular with corporate travellers. This 4.5-stars option includes amenities such as pillow top mattresses and an electric car charging station. Marriott's OceanWatch at Grande Dunes also scores top marks from business guests. Make use of a barbecue grill and a sauna at this 4-stars property in Myrtle Beach.
How many business-friendly hotels are there in South Carolina?
There are 824 business-friendly hotels in South Carolina. Wherever your job is taking you, Expedia makes it a breeze to find the perfect space with the amenities you're looking for.
What are the best cheap business-friendly hotels in South Carolina?
When work is taking you out of town in South Carolina, Expedia will help you find the right business-friendly hotel. Hampton Inn Myrtle Beach-West is a budget pick in Myrtle Beach. A swimming pool and express check-out services are some of its many amenities. Searching for wallet-friendly stays in Charleston? Hampton Inn & Suites Charleston Airport is the first choice for many corporate travellers. It comes with conveniences that make it easy to both work and feel at home, including pool sun loungers and a swimming pool. Business-friendly hotels in South Carolina start at only ฿1,925 a night. There are plenty of interesting and free things to do around South Carolina. If your work trip is taking you to Myrtle Beach, try to find time to check out Myrtle Beach Boardwalk. You can also tour the sights on a shoestring in Charleston. Gibbes Museum of Art is a popular free thing to do here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in South Carolina?
Comfortable and economical, motels are the perfect choice for your next business trip in South Carolina. If a meeting or event takes you to Charleston, check out Days Inn by Wyndham Charleston Historic District. It's around 0.16 kilometres south of downtown and comes with amenities like a terrace and complimentary use of a nearby fitness centre. Days Inn by Wyndham Mt Pleasant-Charleston-Patriots Point also welcomes corporate travellers. It has a swimming pool and pool sun loungers and is located about 5 kilometres northeast of central Charleston.There's plenty to see when you've got some free time in Myrtle Beach. Myrtle Beach Boardwalk and Broadway at the Beach are worth adding to your itinerary.
Are there any family-friendly hotels in South Carolina that are also business friendly?
Certainly. Whether you'd like a stay in South Carolina with a conference room or a quiet space to work solo, con buena conexión wifi Expedia's got you covered. Hilton Grand Holidays Club Ocean 22 Myrtle Beach in Myrtle Beach is a fantastic choice. This 4.5-stars business and family-friendly option comes with conveniences like pillow top mattresses and a cafe. Marriott's OceanWatch at Grande Dunes is another option in Myrtle Beach where corporate travellers can fit in some work while jet-setting with family. A playground and a waterslide are two of the amenities that await you at this 4-stars hotel. Myrtle Beach offers plenty of family-friendly attractions when you're ready to go sightseeing. Myrtle Beach Boardwalk and Broadway at the Beach promise fun for all ages.
Are there any 5-star business-friendly hotels in South Carolina?
While there are no 5-star business-friendly hotels in South Carolina, there are still chic properties to choose from. Visiting Myrtle Beach for work? Marriott's OceanWatch at Grande Dunes is a popular option that has everything you need and more when you're on a business trip. Amenities at this 4-star property include a spa tub and a firepit. Marina Inn At Grande Dunes is another great pick that caters to corporate travellers in Myrtle Beach. Also rated 4 stars and offering golf and a swimming pool, you'll find plenty to love about this hotel.
Why book your business-friendly hotel in South Carolina with Expedia?
With useful amenities like meeting rooms, laundry facilities and free parking, our business-friendly hotels come with everything you'll need to get the job done — and then chill! Enter your preferred travel dates and destination and Expedia will help you do the rest.
How can I find cheap business-friendly hotels in South Carolina?
Expedia can help you narrow down your search for cheap business-friendly hotels in South Carolina. Head to the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work comfortably and efficiently, like free WiFi and included breakfast. You can also choose your hotel star rating and budget to keep costs under control.
What is there to do in South Carolina near my business-friendly hotel?
Whether you enjoy shopping, dining, history or culture, South Carolina has something to suit all tastes! The top city of Myrtle Beach has tons of things to do and see, including Myrtle Beach Boardwalk, Broadway at the Beach and SkyWheel Myrtle Beach. If you're arranging a work trip to Charleston, South Carolina Aquarium, Dock Street Theatre and International African American Museum should be on your itinerary.