Find hotels in Worthington, MO from ฿2,269

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Check prices for these dates

Tonight
25 Dec - 26 Dec
Tomorrow
26 Dec - 27 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Worthington hotels

Lobby
Knights Inn Kirksville

Knights Inn Kirksville

Knights Inn Kirksville
1.5 star property
Kirksville
7.2 out of 10, Good, (250)
Tranquil accommodation with unique layout ensure no neighbors above or below for ultimate relaxation. Free parking and in-room coffeemakers add convenience, while nearby natural attractions await your exploration.
"Cozy and cool."
United States
Lois
The price is ฿2,113
฿2,374 total
includes taxes & fees
26 Dec - 27 Dec
Knights Inn Kirksville
Room, 2 Double Beds, Non Smoking | Pillow-top beds, desk, blackout curtains, free cots/infant beds
Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area
2.5 star property
Kirksville
9.0 out of 10, Wonderful, (152)
Connected to a golf course in Kirksville, this hotel offers complimentary WiFi, daily buffet breakfast, and free parking. Thousand Hills State Park is nearby, with La Plata Station just 13 minutes away.
"The rooms were clean and the breakfast bar is outstanding staff was very friendly and helpful "
United States
Bill
The price is ฿2,020
฿2,269 total
includes taxes & fees
1 Jan - 2 Jan 2026
Super 8 by Wyndham Kirksville-University Area
Free daily buffet breakfast
Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG
2.5 star property
Kirksville
9.2 out of 10, Wonderful, (511)
Located near a train station in Kirksville, this hotel offers a refreshing indoor pool and 24-hour fitness centre. Guests praise the complimentary breakfast and attentive staff. Thousand Hills State Park is nearby, with free WiFi and parking included.
"Excellent service and stay"
United States
Taylor
The price is ฿3,667
฿4,156 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Kirksville - University Area by IHG
Indoor pool
Days Inn by Wyndham Kirksville

Days Inn by Wyndham Kirksville

Days Inn by Wyndham Kirksville
2.0 star property
Kirksville
6.6 out of 10, (1000)
Enjoy a tranquil escape at this Kirksville hotel offering an indoor pool and convenient bar. Located near Thousand Hills State Park with complimentary breakfast, WiFi, and parking. Guests consistently praise the helpful staff and immaculate accommodation.
"Breakfast was great enjoyed the pool"
United States
Dara
The price is ฿2,024
฿2,273 total
includes taxes & fees
28 Dec - 29 Dec
Days Inn by Wyndham Kirksville
Lobby
Hampton Inn Kirksville

Hampton Inn Kirksville

Hampton Inn Kirksville
2.5 star property
Kirksville
9.2 out of 10, Wonderful, (574)
Located near Thousand Hills State Park, this welcoming hotel offers free breakfast, WiFi, and parking. Enjoy morning swims in the indoor pool or workouts in the fitness centre. Business-friendly amenities and a helpful team ensure a comfortable stay in Missouri.
"Better than a typical hotel, premium bedding, great lobby space for families to gather."
United States
Lynn
The price is ฿3,797
฿4,303 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hampton Inn Kirksville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Worthington Hotel Reviews

Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area

10/10 Excellent
"Will be staying here for future visits to Kirksville."
Scott 1-night trip
Posted 4 days ago
Super 8 by Wyndham Kirksville-University Area
Thousand Hills

Thousand Hills

10/10 Excellent
"Room was in great shape and close to actities I did"
Brice 2-night trip
Posted 2 months ago
Thousand Hills

More cheap stays in Worthington

Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area

1101 Country Club Dr Kirksville MO
The price is ฿2,020 per night from 1 Jan to 2 Jan
฿2,020
฿2,269 total
1 Jan - 2 Jan 2026
includes taxes & fees
9/10 Wonderful! (150 reviews)

Frequently asked questions

What's the best place to stay in Worthington?
Located 17.5 mi (28.2 km) from the heart of Worthington, Super 8 by Wyndham Kirksville-University Area is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Hampton Inn Kirksville and Days Inn by Wyndham Kirksville. See all available top hotels, or vacation rentals in Worthington.
If I need to cancel my hotel reservation in Worthington, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Worthington.
What is staying in Worthington like?
Visitors will definitely enjoy all that Worthington has to offer. There are 45 hotels and other accommodation options in the surrounding area. Find out more about Worthington.
What should I do while I'm visiting Worthington?
Places to visit in the wider area include Thousand Hills State Park, A.T. Still University and Truman State University. Additionally, you'll find Lake Thunderhead in the area. Take a look at what more there is to see and do in Expedia's Worthington guide.
What's the seasonal weather in Worthington?
The hottest months are usually July and August, with an average temperature of 23°C, while the coldest months are January and February, with an average of 0°C. The snowiest months in Worthington are January, November, February and December, with each month seeing an average of 13 cm of snowfall.