Search Hotels Near St Mary's Medical Center, Grand Junction

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28 Dec - 29 Dec
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Our top choices for St Mary's Medical Center hotels

Reception
Castle Creek B&B

Castle Creek B&B

Castle Creek B&B
3.5 star property
0.8 km from St Mary's Medical Center
9.8 out of 10, Exceptional, (208)
"Very pleasant stay…Incredible breakfast"
United States
Michele
Castle Creek B&B
Rooftop terrace
Hotel Maverick

Hotel Maverick

Hotel Maverick
4.0 star property
Capitol Hill, 1.2 km from St Mary's Medical Center
9.6 out of 10, Exceptional, (1001)
"Excellent place to stay in Grand Junction. "
United States
Steve
Hotel Maverick
Restaurant
Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown
2.5 star property
Historic Grand Junction, 2.7 km from St Mary's Medical Center
9.2 out of 10, Wonderful, (1000)
"Good place to stay when you are going on a long trip. Staff was friendly and in a good location of downtown. "
United States
Guru Prasad
The price is ฿2,519
฿2,889 total
includes taxes & fees
7 Jan - 8 Jan 2026
Tru by Hilton Grand Junction Downtown
Property amenity
SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.

SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.

SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.
3.5 star property
Historic Grand Junction, 2.6 km from St Mary's Medical Center
9.0 out of 10, Wonderful, (1004)
"Very nice family hotel with good breakfast."
United States
Margarita
The price is ฿3,879
฿4,470 total
includes taxes & fees
4 Jan - 5 Jan 2026
SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.
Design Double Room, 2 Queen Beds | Premium bedding, down duvets, pillow-top beds, in-room safe
The Hotel Melrose

The Hotel Melrose

The Hotel Melrose
2.0 star property
Historic Grand Junction, 2.7 km from St Mary's Medical Center
9.2 out of 10, Wonderful, (133)
"Love this little hotel!"
United States
Gregory
The price is ฿6,285
฿7,206 total
includes taxes & fees
29 Dec - 30 Dec
The Hotel Melrose
Exterior
Hampton Inn Grand Junction Downtown/Historic Main Street

Hampton Inn Grand Junction Downtown/Historic Main Street

Hampton Inn Grand Junction Downtown/Historic Main Street
2.5 star property
Historic Grand Junction, 2.6 km from St Mary's Medical Center
8.8 out of 10, Excellent, (1000)
"Very clean, well managed, and a nice overall stay"
United States
Jeff
The price is ฿3,028
฿3,472 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn Grand Junction Downtown/Historic Main Street
Terrace/patio
Fairfield Inn & Suites by Marriott Grand Junction Downtown

Fairfield Inn & Suites by Marriott Grand Junction Downtown

Fairfield Inn & Suites by Marriott Grand Junction Downtown
2.5 star property
Historic Grand Junction, 2.6 km from St Mary's Medical Center
8.8 out of 10, Excellent, (688)
"Steve was super friendly and accommodating at both check in and check out. "
United States
Morey
The price is ฿3,796
฿4,353 total
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Grand Junction Downtown
Lobby
Quality Inn Grand Junction near University

Quality Inn Grand Junction near University

Quality Inn Grand Junction near University
3.0 star property
Horizon Drive District, 2.8 km from St Mary's Medical Center
8.6 out of 10, Excellent, (1001)
"Great staff."
United States
Manford
The price is ฿1,715
฿1,966 total
includes taxes & fees
4 Jan - 5 Jan 2026
Quality Inn Grand Junction near University
Terrace/patio
Doubletree Hotel Grand Junction

Doubletree Hotel Grand Junction

Doubletree Hotel Grand Junction
4.0 star property
Horizon Drive District, 3 km from St Mary's Medical Center
8.2 out of 10, Very good, (1003)
"Nice looking hotel."
United States
Richard
The price is ฿2,759
฿3,164 total
includes taxes & fees
13 Jan - 14 Jan 2026
Doubletree Hotel Grand Junction
Free daily continental breakfast
Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado
2.0 star property
Horizon Drive District, 2.8 km from St Mary's Medical Center
7.4 out of 10, Good, (1003)
"Great staff"
United States
Theresa
The price is ฿1,622
฿1,859 total
includes taxes & fees
2 Jan - 3 Jan 2026
Super 8 by Wyndham Grand Junction Colorado
Reception
Ville 718

Ville 718

Ville 718
2.5 star property
Horizon Drive District, 2.7 km from St Mary's Medical Center
6.8 out of 10, (354)
"Very nice quiet place while traveling through town. "
United States
Shane
The price is ฿1,831
฿2,100 total
includes taxes & fees
9 Jan - 10 Jan 2026
Ville 718
Exterior
Days Inn by Wyndham Grand Junction

Days Inn by Wyndham Grand Junction

Days Inn by Wyndham Grand Junction
3.0 star property
Horizon Drive District, 2.5 km from St Mary's Medical Center
5.4 out of 10, (1000)
"Very nice and clean "
United States
Ashley
The price is ฿1,451
฿1,664 total
includes taxes & fees
2 Jan - 3 Jan 2026
Days Inn by Wyndham Grand Junction
House, 2 Bedrooms | Private kitchen | Fridge, oven, coffee/tea maker, toaster
Vintage Parlor 2 Bedroom Home

Vintage Parlor 2 Bedroom Home

Vintage Parlor 2 Bedroom Home
3.0 star property
Hawthorne Park, 1.6 km from St Mary's Medical Center
The price is ฿3,983
฿13,116 total
includes taxes & fees
28 Jan - 29 Jan 2026
Vintage Parlor 2 Bedroom Home
House, 1 Bedroom | Living area | Smart TV
Home Away From Home 1 Bedroom Home

Home Away From Home 1 Bedroom Home

Home Away From Home 1 Bedroom Home
3.0 star property
Hawthorne Park, 1.7 km from St Mary's Medical Center
The price is ฿3,869
฿12,950 total
includes taxes & fees
4 Jan - 5 Jan 2026
Home Away From Home 1 Bedroom Home
Townhome, 3 Bedrooms | Living area | Smart TV
The Maverick Haus 3 Bedroom Townhouse

The Maverick Haus 3 Bedroom Townhouse

The Maverick Haus 3 Bedroom Townhouse
3.0 star property
Grandview, 1.5 km from St Mary's Medical Center
The price is ฿6,690
฿20,005 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Maverick Haus 3 Bedroom Townhouse
House, 2 Bedrooms | BBQ/picnic Area
My Home Is Your Home 2 Bedroom Home

My Home Is Your Home 2 Bedroom Home

My Home Is Your Home 2 Bedroom Home
3.0 star property
Hawthorne Park, 1.7 km from St Mary's Medical Center
The price is ฿3,983
฿13,116 total
includes taxes & fees
19 Jan - 20 Jan 2026
My Home Is Your Home 2 Bedroom Home
Free continental breakfast
La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction
3.0 star property
Horizon Drive District, 3.3 km from St Mary's Medical Center
8.8 out of 10, Excellent, (2739)
"Easy check in with super friendly staff!!"
United States
Andrew
The price is ฿2,300
฿2,637 total
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Grand Junction
Exterior
Holiday Inn & Suites Grand Junction by IHG

Holiday Inn & Suites Grand Junction by IHG

Holiday Inn & Suites Grand Junction by IHG
3.0 star property
Horizon Drive District, 3.3 km from St Mary's Medical Center
8.6 out of 10, Excellent, (1001)
"Room was clean, front office staff was nice. "
United States
Patricia
The price is ฿2,762
฿3,167 total
includes taxes & fees
30 Dec - 31 Dec
Holiday Inn & Suites Grand Junction by IHG
Room, 2 Double Beds, Accessible, Non Smoking | Iron/ironing board, free cots/infant beds, rollaway beds, free WiFi
Econo Lodge Grand Junction North

Econo Lodge Grand Junction North

Econo Lodge Grand Junction North
2.0 star property
Horizon Drive District, 3.2 km from St Mary's Medical Center
8.4 out of 10, Very good, (1000)
"Hotel was easy to find and worked quite well for a good night sleep after driving 13 hours. "
United States
Peter
The price is ฿1,542
฿1,768 total
includes taxes & fees
7 Jan - 8 Jan 2026
Econo Lodge Grand Junction North
Terrace/patio
Home2 Suites by Hilton Grand Junction Northwest

Home2 Suites by Hilton Grand Junction Northwest

Home2 Suites by Hilton Grand Junction Northwest
3.0 star property
24 Road Corridor, 3.8 km from St Mary's Medical Center
9.2 out of 10, Wonderful, (884)
"Friendly staff, great breakfast."
United States
Larry
The price is ฿4,540
฿5,205 total
includes taxes & fees
4 Jan - 5 Jan 2026
Home2 Suites by Hilton Grand Junction Northwest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St Mary's Medical Center Hotel Reviews

Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown

10/10 Excellent
"Friendly staff, free cocktail, pleasant atmosphere "
Amy 1-night trip
Posted 4 days ago
Tru by Hilton Grand Junction Downtown

Hotels near other St Mary's Medical Center attractions

Western Colorado Center for the Arts

3.7/5 (46 reviews)
You can spend time studying the exhibits at Western Colorado Center for the Arts during your trip to Grand Junction. Visit the notable monuments and top-notch restaurants in this family-friendly area.
See properties

Elliott Tennis Center

Catch an event at Elliott Tennis Center during your trip to Grand Junction.
See properties

Frequently asked questions

What's the area like around St Mary's Medical Center?
St Mary's Medical Center is located in Grand Junction. This scenic area is known for its selection of wineries and hiking. If you're looking for a convenient place to stay, take a look at the 38 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near St Mary's Medical Center?
Hotel Maverick is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and a fitness centre. It's located just a short 0.7 mi (1.2 km) from St Mary's Medical Center. Another good option is Castle Creek B&B, located just 0.5 mi (0.8 km) away.
How many hotels can I expect to find near St Mary's Medical Center?
Expedia has 38 hotels and other accommodation options within a mile from St Mary's Medical Center.
If I need to cancel the hotel reservation for my stay near St Mary's Medical Center, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to get top deals close to St Mary's Medical Center.
What can I see and do near St Mary's Medical Center?
You'll want to browse the exhibits at Cross Orchards Historic Site and John McConnell Math and Science Center. You might spend a leisurely day outdoors at Western Colorado Botanical Gardens and Canyon View Park. Create some family memories at Bananas Fun Park, Grand Junction Motor Speedway and Mesa County Fairgrounds while you're exploring the area around St Mary's Medical Center.