A space shuttle exhibit with a large model of a space shuttle, a red pillar, and informational displays.

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Our top choices for St. Louis Science Center hotels

Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 1 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Great Breakfast Great Staff"
United States
Alan
The price is ฿4,805
฿5,666 total
includes taxes & fees
20 Jul - 21 Jul
Hampton Inn & Suites St. Louis at Forest Park

Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park
3.0 star property
2 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,001 reviews)
"Enjoyed our stay"
United States
Sheryl
The price is ฿4,954
฿5,793 total
includes taxes & fees
5 Jul - 6 Jul
Drury Inn & Suites St. Louis Forest Park

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End, 1.8 km from St. Louis Science Center
9.0 out of 10, Wonderful, (1,014 reviews)
"Great hotel!"
United States
Terence Peter
The price is ฿5,369
฿7,314 total
includes taxes & fees
5 Jul - 6 Jul
The Royal Sonesta Chase Park Plaza St. Louis

AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End, 1.8 km from St. Louis Science Center
9.0 out of 10, Wonderful, (773 reviews)
"Nice area to walk to dinner and drinks"
United States
patricia
The price is ฿5,069
฿5,977 total
includes taxes & fees
10 Jul - 11 Jul
AC Hotel St. Louis Central West End

Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown
3.0 star property
Midtown, 2.7 km from St. Louis Science Center
9.0 out of 10, Wonderful, (767 reviews)
"Nice stay. Staff was nice."
United States
Regina
The price is ฿4,802
฿5,615 total
includes taxes & fees
13 Jul - 14 Jul
Element by Marriott St. Louis Midtown

Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 0.9 km from St. Louis Science Center
8.6 out of 10, Excellent, (1,001 reviews)
"Breakfast is different from every other hotel breakfast which is refreshing. Nice accommodations."
United States
Brian
The price is ฿5,240
฿6,127 total
includes taxes & fees
19 Jul - 20 Jul
Home2 Suites by Hilton St. Louis/Forest Park

Aloft by Marriott St. Louis Cortex

Aloft by Marriott St. Louis Cortex
3.0 star property
Central West End, 1.8 km from St. Louis Science Center
8.6 out of 10, Excellent, (958 reviews)
"Great Stay"
United States
Larry
The price is ฿3,787
฿4,428 total
includes taxes & fees
5 Jul - 6 Jul
Aloft by Marriott St. Louis Cortex

Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End, 1.7 km from St. Louis Science Center
8.6 out of 10, Excellent, (1,001 reviews)
"Great hotel in a nice spot - close to both downtown and SLU/Wash U. Nice staff and clean room. Great coffee bar for the AM."
United States
Jason
The price is ฿4,323
฿5,462 total
includes taxes & fees
19 Jul - 20 Jul
Hotel Indigo St Louis - Central West End by IHG

The West End

The West End
2.0 star property
Central West End, 2.3 km from St. Louis Science Center
8.6 out of 10, Excellent, (569 reviews)
"Great location"
United States
Joe
The price is ฿3,663
฿4,948 total
includes taxes & fees
6 Jul - 7 Jul
The West End

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End, 1.3 km from St. Louis Science Center
8.2 out of 10, Very good, (1,003 reviews)
"Beautiful hotel in a convenient locations. Walking distance to great restaurants and coffee shops."
United States
Gary
The price is ฿4,348
฿5,127 total
includes taxes & fees
2 Aug - 3 Aug
DoubleTree by Hilton St. Louis Forest Park

Central West End B&B

Central West End B&B
3.5 star property
Central West End, 3 km from St. Louis Science Center
8.0 out of 10, Very good, (56 reviews)
"Really enjoyed the comfort. I would recommend this place to anyone. Very nice breakfast also!!! "
United States
Stacee
The price is ฿5,474
฿6,887 total
includes taxes & fees
3 Jul - 4 Jul
Central West End B&B

Forest Park Hotel by MDR

Forest Park Hotel by MDR
3.0 star property
The Hill, 1.8 km from St. Louis Science Center
7.4 out of 10, Good, (1,620 reviews)
"Good place to stay"
United States
Jeremy
The price is ฿2,459
฿3,030 total
includes taxes & fees
5 Jul - 6 Jul
Forest Park Hotel by MDR

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
2.5 star property
The Hill, 1.8 km from St. Louis Science Center
5.8 out of 10, (1,002 reviews)
"Clean hotel, nice service!!"
United States
Mary
The price is ฿2,811
฿3,287 total
includes taxes & fees
5 Jul - 6 Jul
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 

Spacious 2BR unit near BJ Hospital

Spacious 2BR unit near BJ Hospital
2.0 star property
Central West End, 2.3 km from St. Louis Science Center
2.0 out of 10, (1 review)
"Do not stay here, the host never responded to any messages and we were unable to checkin. We were left seeking other accommodations after hotels.com took almost full payment for a months stay from us and has yet to return it because “they cannot reach the host” . This is a lot of money to be held from us unavailable to make another booking to replace this one. It has been almost 2 months and hotels.com is not responding to my emails about my refund. "
United States
Eric
The price is ฿2,843
฿5,375 total
includes taxes & fees
16 Jul - 17 Jul
Spacious 2BR unit near BJ Hospital

Grand Center Inn

Grand Center Inn
3.0 star property
3.5 km from St. Louis Science Center
9.4 out of 10, Exceptional, (102 reviews)
"Lovely room, easy check in, close to Fox, comfy bed"
United States
Leon and Janis
The price is ฿5,952
฿7,019 total
includes taxes & fees
19 Jul - 20 Jul
Grand Center Inn

The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
4.3 km from St. Louis Science Center
9.4 out of 10, Exceptional, (594 reviews)
"Great location, restaurant was good too. Staff was nice."
United States
RICHOO Bijoo
The price is ฿4,495
฿5,169 total
includes taxes & fees
3 Jul - 4 Jul
The Knight Center at Washington University

Benton Park Inn

Benton Park Inn
3.5 star property
5.5 km from St. Louis Science Center
9.6 out of 10, Exceptional, (335 reviews)
"My 1st Bed&Breakfast! Dan and Rosie made that experience awesome!"
United States
Leidy
The price is ฿4,954
฿5,793 total
includes taxes & fees
5 Jul - 6 Jul
Benton Park Inn

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
3.7 km from St. Louis Science Center
9.0 out of 10, Wonderful, (1,053 reviews)
"Rooms were clean, bar was great, staff was excellent and very helpful "
United States
Paula
The price is ฿3,431
฿4,047 total
includes taxes & fees
5 Jul - 6 Jul
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Moonrise Hotel

Moonrise Hotel
4.0 star property
3.8 km from St. Louis Science Center
9.0 out of 10, Wonderful, (1,987 reviews)
"Super convenient location, friendly staff, cool decor! Will definitely stay here again."
United States
Lindsay
The price is ฿4,727
฿5,622 total
includes taxes & fees
12 Jul - 13 Jul
Moonrise Hotel

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
5.5 km from St. Louis Science Center
9.4 out of 10, Exceptional, (894 reviews)
"Clean room, comfy bed, friendly staff, great location!! Would definitely stay here again!!"
United States
MARY
The price is ฿3,940
฿4,805 total
includes taxes & fees
2 Aug - 3 Aug
Courtyard by Marriott St. Louis Brentwood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to St. Louis Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Indoor pool
Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
9.4
Exceptional
1,003 reviews
View
Lobby
Drury Inn & Suites St. Louis Forest Park
3.0 star property
9.4
Exceptional
1,001 reviews
View
Seasonal outdoor pool
The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
9.0
Wonderful
1,014 reviews
View
Lobby
AC Hotel St. Louis Central West End
4.0 star property
9.0
Wonderful
773 reviews
View
Courtyard
Element by Marriott St. Louis Midtown
3.0 star property
9.0
Wonderful
767 reviews
View

Top St. Louis Science Center Hotel Reviews

Hotels near other St. Louis Science Center attractions

Frequently asked questions

What's the area like around St. Louis Science Center?
St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, take a look at the 60 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near St. Louis Science Center?
Hampton Inn & Suites St. Louis at Forest Park is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.6 mi (1 km) from St. Louis Science Center. Other good choices within a short distance include DoubleTree by Hilton St. Louis Forest Park and Home2 Suites by Hilton St. Louis/Forest Park.
How many hotels should I expect to find close to St. Louis Science Center?
Expedia has 60 hotels and other accommodation options within a mile from St. Louis Science Center.
If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals near St. Louis Science Center.
What can I see and do near St. Louis Science Center?
Cathedral Basilica of St. Louis, Missouri History Museum and St. Louis Art Museum feature captivating exhibits. St. Louis Union Station, Jewel Box and Cherokee Street are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at The Muny Theater, Fox Theater and Powell Symphony Hall.