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16 Dec - 17 Dec
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17 Dec - 18 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for St. Jude Children's Research Hospital hotels

Executive Studio Suite, 1 King Bed with Sofa bed, Non Smoking, Ground Floor | In-room dining
The Moose

The Moose

The Moose
4.0 star property
1.2 km from St. Jude Children's Research Hospital
10.0 out of 10, Exceptional, (188)
"I really loved staying here it’s close to everything clean and just like the pictures."
United States
Latasha
The Moose
4 bedrooms, premium bedding, memory-foam beds, individually decorated
Abode Memphis - Pontotoc

Abode Memphis - Pontotoc

Abode Memphis - Pontotoc
5.0 star property
Downtown Memphis, 2.1 km from St. Jude Children's Research Hospital
10.0 out of 10, Exceptional, (6)
"The house was absolutely excellent. The space was perfect, clean, and quiet. "
United States
Myra
The price is ฿4,539
฿15,010 total
includes taxes & fees
21 Dec - 22 Dec
Abode Memphis - Pontotoc
Exterior detail
River Inn of Harbor Town

River Inn of Harbor Town

River Inn of Harbor Town
4.0 star property
1.3 km from St. Jude Children's Research Hospital
9.6 out of 10, Exceptional, (784)
"A very nice area and hotel accomodations. Staff also very nice. "
United States
Pablo
River Inn of Harbor Town
Signature Loft, 1 Bedroom, Non Smoking, City View | In-room dining
The Stallion

The Stallion

The Stallion
4.0 star property
Downtown Memphis, 2.6 km from St. Jude Children's Research Hospital
9.8 out of 10, Exceptional, (172)
"Staff very friendly and helpful. Comfortable, good location, historical. Nice stay"
United States
Karen
The price is ฿2,961
฿5,572 total
includes taxes & fees
6 Jan - 7 Jan 2026
The Stallion
Egyptian cotton sheets, premium bedding, pillow-top beds, minibar
ARRIVE Memphis

ARRIVE Memphis

ARRIVE Memphis
4.0 star property
South Main, 2.7 km from St. Jude Children's Research Hospital
9.6 out of 10, Exceptional, (1003)
"Great stay "
United States
LaKera
The price is ฿5,509
฿6,605 total
includes taxes & fees
25 Dec - 26 Dec
ARRIVE Memphis
Exterior
La Quinta Inn & Suites by Wyndham Memphis Downtown

La Quinta Inn & Suites by Wyndham Memphis Downtown

La Quinta Inn & Suites by Wyndham Memphis Downtown
3.0 star property
Downtown Memphis, 1.4 km from St. Jude Children's Research Hospital
9.2 out of 10, Wonderful, (1299)
"Great stay! Polite,friendly staff. Very clean!!"
United States
Nicholas
The price is ฿3,639
฿4,384 total
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Memphis Downtown
View from property
Residence Inn by Marriott Memphis Downtown

Residence Inn by Marriott Memphis Downtown

Residence Inn by Marriott Memphis Downtown
3.0 star property
Downtown Memphis, 1.5 km from St. Jude Children's Research Hospital
9.2 out of 10, Wonderful, (897)
"Friendly staff, well kept and comfortable rooms. "
United States
Joanne
The price is ฿3,796
฿4,571 total
includes taxes & fees
3 Jan - 4 Jan 2026
Residence Inn by Marriott Memphis Downtown
Room
Home2 Suites By Hilton Memphis Downtown

Home2 Suites By Hilton Memphis Downtown

Home2 Suites By Hilton Memphis Downtown
3.0 star property
Downtown Memphis, 2.3 km from St. Jude Children's Research Hospital
9.4 out of 10, Exceptional, (22)
"Good location..clean hotel "
United States
Ernestine
The price is ฿3,425
฿4,130 total
includes taxes & fees
28 Dec - 29 Dec
Home2 Suites By Hilton Memphis Downtown
Exterior
Big Cypress Lodge

Big Cypress Lodge

Big Cypress Lodge
5.0 star property
Pinch District, 0.9 km from St. Jude Children's Research Hospital
9.0 out of 10, Wonderful, (1718)
"The lodge was amazing, we will be back soon."
United States
Carl
The price is ฿7,209
฿9,253 total
includes taxes & fees
12 Jan - 13 Jan 2026
Big Cypress Lodge
Seasonal outdoor pool
Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown
2.5 star property
Downtown Memphis, 1.1 km from St. Jude Children's Research Hospital
8.8 out of 10, Excellent, (1008)
"Great hotel "
United States
Andre
The price is ฿2,707
฿3,277 total
includes taxes & fees
21 Dec - 22 Dec
Comfort Inn Memphis Downtown
Lobby
Aloft Memphis Downtown

Aloft Memphis Downtown

Aloft Memphis Downtown
3.0 star property
Downtown Memphis, 1.1 km from St. Jude Children's Research Hospital
8.8 out of 10, Excellent, (63)
"Great stay"
United States
Joe Lee
The price is ฿3,463
฿4,175 total
includes taxes & fees
21 Dec - 22 Dec
Aloft Memphis Downtown
Exterior
Hilton Garden Inn Memphis Downtown Beale Street

Hilton Garden Inn Memphis Downtown Beale Street

Hilton Garden Inn Memphis Downtown Beale Street
3.0 star property
Downtown Memphis, 1.5 km from St. Jude Children's Research Hospital
8.8 out of 10, Excellent, (1001)
"Great stay!"
United States
Kimberly Meeks
The price is ฿3,501
฿4,220 total
includes taxes & fees
28 Dec - 29 Dec
Hilton Garden Inn Memphis Downtown Beale Street
Luxury Penthouse, 6 Bedrooms | Individually decorated, individually furnished, laptop workspace
The Rambler

The Rambler

The Rambler
4.0 star property
South Main, 2.5 km from St. Jude Children's Research Hospital
9.2 out of 10, Wonderful, (524)
"Walkable, neat spot."
United States
Teresa
The price is ฿4,157
฿4,999 total
includes taxes & fees
17 Dec - 18 Dec
The Rambler
Terrace/patio
Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis
4.0 star property
Downtown Memphis, 2 km from St. Jude Children's Research Hospital
8.8 out of 10, Excellent, (1405)
"Amazing hotel and staff and very convenient location to restaurants and shopping. "
United States
Timothy
The price is ฿4,221
฿5,076 total
includes taxes & fees
21 Dec - 22 Dec
Hyatt Centric Beale Street Memphis
Exterior
The Central Station Memphis, Curio Collection by Hilton

The Central Station Memphis, Curio Collection by Hilton

The Central Station Memphis, Curio Collection by Hilton
4.0 star property
South Main, 2.9 km from St. Jude Children's Research Hospital
9.0 out of 10, Wonderful, (1007)
"Wonderful staff and ambiance "
United States
Gabriela
The price is ฿3,518
฿4,240 total
includes taxes & fees
21 Dec - 22 Dec
The Central Station Memphis, Curio Collection by Hilton
Hypo-allergenic bedding, pillow-top beds, minibar, in-room safe
The Westin Memphis Beale Street

The Westin Memphis Beale Street

The Westin Memphis Beale Street
4.0 star property
Downtown Memphis, 1.9 km from St. Jude Children's Research Hospital
8.8 out of 10, Excellent, (1003)
"Room and location was very nice. "
United States
DEREX
The price is ฿4,795
฿5,758 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Westin Memphis Beale Street
Exterior
Courtyard by Marriott Downtown Memphis

Courtyard by Marriott Downtown Memphis

Courtyard by Marriott Downtown Memphis
3.0 star property
Downtown Memphis, 1.2 km from St. Jude Children's Research Hospital
8.6 out of 10, Excellent, (951)
"Well located for restaurants. Easy to get to from the interstate. Lacking friendliness. No lotion in the bathroom and no complimentary coffee in the lobby in the morning. "
United States
Mary Nancy
The price is ฿3,715
฿4,474 total
includes taxes & fees
21 Dec - 22 Dec
Courtyard by Marriott Downtown Memphis
Bar (on property)
Canopy by Hilton Memphis Downtown

Canopy by Hilton Memphis Downtown

Canopy by Hilton Memphis Downtown
4.0 star property
Downtown Memphis, 1.5 km from St. Jude Children's Research Hospital
8.6 out of 10, Excellent, (1002)
"Courteous staff, great location and walking distance to everything. Wining and dining. Food and ambience are superb. "
United States
Dennis
The price is ฿3,640
฿4,385 total
includes taxes & fees
23 Dec - 24 Dec
Canopy by Hilton Memphis Downtown
Breakfast area
voco Hotel Napoleon Memphis by IHG

voco Hotel Napoleon Memphis by IHG

voco Hotel Napoleon Memphis by IHG
4.0 star property
Downtown Memphis, 1.3 km from St. Jude Children's Research Hospital
8.6 out of 10, Excellent, (977)
"The staff was very courteous. The room was clean and the bedding was very comfortable. Although my reason for staying here was to have a staycation and just relax in my room, the location of this property is great and very close to downtown attractions."
United States
Dimika
The price is ฿3,998
฿4,811 total
includes taxes & fees
4 Jan - 5 Jan 2026
voco Hotel Napoleon Memphis by IHG
Exterior
Hampton Inn & Suites Memphis-Beale Street

Hampton Inn & Suites Memphis-Beale Street

Hampton Inn & Suites Memphis-Beale Street
2.5 star property
Downtown Memphis, 1.8 km from St. Jude Children's Research Hospital
8.6 out of 10, Excellent, (1233)
"Excellent hotel in a great location "
United States
Ralph
The price is ฿3,501
฿4,220 total
includes taxes & fees
23 Dec - 24 Dec
Hampton Inn & Suites Memphis-Beale Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Jude Children's Research Hospital Hotel Reviews

voco Hotel Napoleon Memphis by IHG

voco Hotel Napoleon Memphis by IHG

10/10 Excellent
"The staff was very courteous. The room was clean and the bedding was very comfortable. Although my reason for staying here was to have a staycation and just relax in my room, the location of this property is great and very close to downtown attractions."
Dimika 1-night trip
Posted 4 days ago
voco Hotel Napoleon Memphis by IHG

Hotels near other St. Jude Children's Research Hospital attractions

Memphis_CannonCenterforPerformingArts_553248621533125114-3

Cannon Center for Performing Arts

You can make plans for a show at Cannon Center for Performing Arts during your trip to Memphis. Experience the fascinating museums and entertainment choices in this romantic area.
See properties
Memphis_MississippiRiverMuseumatMudIsland_6080321-2

Mississippi River Museum at Mud Island

You can spend time browsing the exhibits at Mississippi River Museum at Mud Island during your trip to Memphis. Experience the area's entertainment choices and fascinating museums.
See properties

Frequently asked questions

What's the area like around St. Jude Children's Research Hospital?
St. Jude Children's Research Hospital is located in Memphis. This historic area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 141 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near St. Jude Children's Research Hospital?
Hu. Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a fitness centre and a bar. It's located just a short 0.9 mi (1.4 km) from St. Jude Children's Research Hospital. Other good options within a short distance include Big Cypress Lodge and Comfort Inn Memphis Downtown.
How many hotels will I find near St. Jude Children's Research Hospital?
Expedia has 141 hotels and other accommodation options within a mile from St. Jude Children's Research Hospital.
If I need to cancel the hotel reservation for my stay near St. Jude Children's Research Hospital, will I receive a refund?
Yes, most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best deals available near St. Jude Children's Research Hospital.
What can I see and do near St. Jude Children's Research Hospital?
Mississippi River Museum at Mud Island, Mud Island River Park and Memphis Music Hall of Fame feature captivating exhibits. While you're exploring, swing by The Peabody Memphis, Sun Studio and Lorraine Motel to learn a bit about the area. You can watch performances at Cannon Center for Performing Arts, Orpheum Theatre and Minglewood Hall if you're interested in local theatre.

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