Find hotels in St. Charles, MN from ฿2,074
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in St. Charles
Pet friendly
Apartment
Condo
Family friendly
Waterpark
Check prices for these dates
Tonight
30 Aug - 31 AugTomorrow
31 Aug - 1 SepNext weekend
4 Sep - 6 SepIn two weeks
11 Sep - 13 SepOur top choices for St. Charles hotels
1. AmericInn by Wyndham Winona
AmericInn by Wyndham WinonaWinona
SANDRA
฿4,025
฿4,493 total
includes taxes & fees
6 Sept - 7 Sept
2. Comfort Inn & Suites Rochester South Mayo Clinic
Comfort Inn & Suites Rochester South Mayo ClinicRochester
Deborah
฿2,747
฿3,162 total
includes taxes & fees
30 Sept - 1 Oct
3. Spark by Hilton Rochester South
Spark by Hilton Rochester SouthRochester
Helena
฿2,552
฿2,938 total
includes taxes & fees
5 Sept - 6 Sept
4. Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHGRochester
Stephanie
฿3,377
฿3,888 total
includes taxes & fees
27 Sept - 28 Sept
5. Hampton Inn Rochester-South
Hampton Inn Rochester-SouthRochester
Lynne
฿3,367
฿3,876 total
includes taxes & fees
7 Sept - 8 Sept
6. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic SRochester
Jason
฿2,505
฿2,884 total
includes taxes & fees
6 Sept - 7 Sept
7. AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo ClinicRochester
Cathy
฿2,580
฿2,970 total
includes taxes & fees
6 Sept - 7 Sept
8. Days Inn by Wyndham Winona
Days Inn by Wyndham WinonaWinona
LeAndre
฿2,252
฿2,513 total
includes taxes & fees
6 Sept - 7 Sept
9. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. MarysKutzky Park
Jon
฿3,695
฿4,254 total
includes taxes & fees
18 Sept - 19 Sept
10. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaHistoric Southwest
Sarah
฿3,781
฿4,353 total
includes taxes & fees
6 Sept - 7 Sept
11. Home2 Suites by Hilton Rochester Mayo Clinic Area
Home2 Suites by Hilton Rochester Mayo Clinic AreaRochester
Vickie
฿4,046
฿4,657 total
includes taxes & fees
5 Sept - 6 Sept
12. Residence Inn by Marriott Rochester Mayo Clinic Area South
Residence Inn by Marriott Rochester Mayo Clinic Area SouthRochester
Richard
฿4,536
฿5,222 total
includes taxes & fees
11 Sept - 12 Sept
13. Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic AreaDowntown Rochester
Valarie
฿4,142
฿4,769 total
includes taxes & fees
4 Sept - 5 Sept
14. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHGKutzky Park
Janet
฿3,576
฿4,117 total
includes taxes & fees
4 Sept - 5 Sept
15. Hampton Inn & Suites Rochester-North
Hampton Inn & Suites Rochester-NorthRochester
Albert
฿3,231
฿3,720 total
includes taxes & fees
5 Sept - 6 Sept
16. Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic AreaRochester
Markus
฿2,270
฿2,613 total
includes taxes & fees
20 Sept - 21 Sept
17. TownePlace Suites by Marriott Rochester Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic AreaKutzky Park
฿4,205
฿4,841 total
includes taxes & fees
4 Sept - 5 Sept
18. Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic AreaDowntown Rochester
Mary Jo
฿4,768
฿5,489 total
includes taxes & fees
18 Sept - 19 Sept
19. Fairfield Inn & Suites by Marriott Winona
Fairfield Inn & Suites by Marriott WinonaWinona
Mary
฿4,738
฿5,289 total
includes taxes & fees
6 Sept - 7 Sept
20. Super 8 by Wyndham Rochester Mayo Clinic Area
Super 8 by Wyndham Rochester Mayo Clinic AreaRochester
Amber
฿1,801
฿2,074 total
includes taxes & fees
6 Sept - 7 Sept
Learn more about St. Charles
Top St. Charles Hotel Reviews
Staybridge Suites Rochester - Mayo Clinic Area by IHG
10/10 Excellent
"Great property. Free breakfast, happy hour a few days, huge lobby and patio are. Convenient shuttle to Mayo Clinic. Fully stocked kitchens, coffee, and dishwasher. Laundry on site if needed."
Aspen Select
10/10 Excellent
"Construction in the area is crazy, but if you are looking for a good price near the Mayo Clinic then this is your hotel. The sister property was almost 3x the price. Still has good access during Mayo construction. Directly across from Saint Mary’s"
Green Gables Inn
10/10 Excellent
"Wonderful property. Comfortable beds. Gorgeous grounds on the river. Brian & Tracy were very welcoming"
Kahler Grand Hotel
8/10 Good
"Toilets were too low for seniors….put higher toilets in. It is ridicules to have to sit almost of the floor, especially in room 562!!! Otherwise every thing was wonderful!!"
Hyatt House Rochester/Mayo Clinic Area
10/10 Excellent
"This property has a good location and since it’s newer, that’s an added bonus. They have a complimentary, elevated breakfast which is great."
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
8/10 Good
"Check out was very confusing. It took about a half hour and I am still not sure if the billing was correct. Food was fine."
Kahler Inn and Suites - Mayo Clinic Area
10/10 Excellent
"The hotel was nice and clean, staff were very pleasant, breakfast was a big tasty buffet. The only complaint was the parking garage was very little and barely fit my mid size SUV because of how low the ceiling was, but there is another garage next to the hotel that was actually cheaper. Also, being on the side where all the construction was going on, but I get it they had to start super early because of the heat. Most importantly though it was with walking distance from all of my Mayo appts and several restaurants."
Hotel Indigo Rochester – Mayo Clinic Area by IHG
10/10 Excellent
"This is my first time staying at Hotel Indigo. The staff was amazing. I had to keep adding nights and they were so accommodating. The room was just right. It was clean , well stocked and easy access to the Mayo Clinic. I really liked the front desk people. Super friendly and helpful. Love the attached restaurant!"
More cheap stays in St. Charles
Super 8 by Wyndham Rochester Mayo Clinic Area
106 SE 21st Street Rochester MN
฿1,801
฿2,074 total
6 Sept - 7 Sept
includes taxes & fees
7.8/10 Good! (1,002 reviews)
Super 8 by Wyndham Winona MN
1025 Sugar Loaf Rd Winona MN
฿2,152
฿2,445 total
13 Sept - 14 Sept
includes taxes & fees
Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
฿2,503
฿2,882 total
31 Aug - 1 Sept
includes taxes & fees
8/10 Very good! (1,007 reviews)
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1517 16th St Sw Rochester MN
฿3,271
฿3,766 total
20 Sept - 21 Sept
includes taxes & fees
Hampton Inn Rochester-South
1755 S Broadway Rochester MN
฿3,367
฿3,876 total
7 Sept - 8 Sept
includes taxes & fees
Brentwood Inn & Suites
123 Fourth Ave. NW Rochester MN
฿4,139
฿4,765 total
3 Sept - 4 Sept
includes taxes & fees
8.8/10 Excellent! (1,002 reviews)
