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Find hotels in Southern Illinois, IL from ฿1,938
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Our top choices for Southern Illinois hotels

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
9.6 out of 10, Exceptional, (1,663 reviews)
The price is ฿3,585
฿4,044 total
includes taxes & fees
3 May - 4 May

Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
8.8 out of 10, Excellent, (1,007 reviews)
The price is ฿2,793
฿3,099 total
includes taxes & fees
12 Apr - 13 Apr

Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
9.0 out of 10, Wonderful, (1,000 reviews)
The price is ฿3,683
฿4,152 total
includes taxes & fees
19 Apr - 20 Apr

La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
9.2 out of 10, Wonderful, (1,002 reviews)
The price is ฿3,158
฿3,536 total
includes taxes & fees
19 Apr - 20 Apr

Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
9.4 out of 10, Exceptional, (1,007 reviews)
The price is ฿3,424
฿4,108 total
includes taxes & fees
20 Apr - 21 Apr

Comfort Suites Mount Vernon
Comfort Suites Mount VernonMount Vernon
9.0 out of 10, Wonderful, (1,024 reviews)
The price is ฿3,641
฿4,106 total
includes taxes & fees
12 Apr - 13 Apr

Best Western Delta Inn
Best Western Delta InnEffingham
9.2 out of 10, Wonderful, (1,009 reviews)
The price is ฿2,911
฿3,260 total
includes taxes & fees
3 May - 4 May

Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
9.6 out of 10, Exceptional, (726 reviews)
The price is ฿4,477
฿4,968 total
includes taxes & fees
19 Apr - 20 Apr

Home2 Suites By Hilton Effingham
Home2 Suites By Hilton EffinghamEffingham
9.8 out of 10, Exceptional, (40 reviews)
The price is ฿4,479
฿5,016 total
includes taxes & fees
3 May - 4 May

The Principal Hotel
The Principal HotelColumbia
9.8 out of 10, Exceptional, (228 reviews)
The price is ฿3,644
฿4,044 total
includes taxes & fees
12 Apr - 13 Apr

Holiday Inn Effingham by IHG
Holiday Inn Effingham by IHGEffingham
9.0 out of 10, Wonderful, (671 reviews)
The price is ฿3,133
฿3,509 total
includes taxes & fees
19 Apr - 20 Apr

SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend LakeWhittington
8.8 out of 10, Excellent, (945 reviews)
The price is ฿2,762
฿3,065 total
includes taxes & fees
28 Apr - 29 Apr

Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHGEffingham
9.4 out of 10, Exceptional, (999 reviews)
The price is ฿3,618
฿4,051 total
includes taxes & fees
3 May - 4 May

Cobblestone Inn & Suites - Altamont
Cobblestone Inn & Suites - AltamontAltamont
9.6 out of 10, Exceptional, (832 reviews)
The price is ฿3,198
฿3,453 total
includes taxes & fees
29 Apr - 30 Apr

Walker's Bluff Casino Resort
Walker's Bluff Casino ResortCarterville
9.4 out of 10, Exceptional, (424 reviews)
The price is ฿4,198
฿4,659 total
includes taxes & fees
14 Apr - 15 Apr

Comfort Inn & Suites Marion I-57
Comfort Inn & Suites Marion I-57Marion
9.4 out of 10, Exceptional, (1,002 reviews)
The price is ฿3,836
฿4,603 total
includes taxes & fees
12 Apr - 13 Apr

Baymont by Wyndham Effingham
Baymont by Wyndham EffinghamEffingham
8.0 out of 10, Very good, (1,000 reviews)
The price is ฿2,197
฿2,438 total
includes taxes & fees
3 May - 4 May

Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview HeightsFairview Heights
9.2 out of 10, Wonderful, (1,011 reviews)
The price is ฿3,323
฿3,754 total
includes taxes & fees
5 May - 6 May

Ramada by Wyndham Vandalia
Ramada by Wyndham VandaliaVandalia
7.8 out of 10, Good, (826 reviews)
The price is ฿2,197
฿2,394 total
includes taxes & fees
22 Apr - 23 Apr

Charleston House Bed & Breakfast Inn
Charleston House Bed & Breakfast InnCharleston
10.0 out of 10, Exceptional, (3 reviews)
The price is ฿3,071
฿3,408 total
includes taxes & fees
21 Apr - 22 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Photo by Southernmost Illinois Tourism Bureau
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Top Southern Illinois Hotel Reviews

Super 8 by Wyndham Troy IL/St. Louis Area
10/10 Excellent
More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
The price is ฿1,717 per night from 16 Apr to 17 Apr
฿1,717
per night
16 Apr - 17 Apr
6.8/10 (1,001 reviews)











































































