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Find hotels in Southern Illinois, IL from ฿2,284
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Our top choices for Southern Illinois hotels

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
9.6 out of 10, Exceptional, (1,687 reviews)
The price is ฿3,626
฿4,090 total
includes taxes & fees
7 Jun - 8 Jun

Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
9.0 out of 10, Wonderful, (1,005 reviews)
The price is ฿3,724
฿4,199 total
includes taxes & fees
7 Jun - 8 Jun

Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
9.6 out of 10, Exceptional, (737 reviews)
The price is ฿4,868
฿5,402 total
includes taxes & fees
25 May - 26 May

La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
9.2 out of 10, Wonderful, (1,002 reviews)
The price is ฿3,555
฿3,980 total
includes taxes & fees
21 Jun - 22 Jun

Comfort Suites Mount Vernon
Comfort Suites Mount VernonMount Vernon
9.0 out of 10, Wonderful, (1,046 reviews)
The price is ฿3,682
฿4,152 total
includes taxes & fees
31 May - 1 Jun

Holiday Inn Effingham by IHG
Holiday Inn Effingham by IHGEffingham
9.2 out of 10, Wonderful, (679 reviews)
The price is ฿3,594
฿4,024 total
includes taxes & fees
7 Jun - 8 Jun

Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
8.8 out of 10, Excellent, (1,000 reviews)
The price is ฿2,875
฿3,191 total
includes taxes & fees
21 Jun - 22 Jun

Best Western Plus MidAmerica Hotel
Best Western Plus MidAmerica HotelMascoutah
9.0 out of 10, Wonderful, (1,002 reviews)
The price is ฿3,723
฿4,243 total
includes taxes & fees
26 May - 27 May

Quality Inn Effingham North
Quality Inn Effingham NorthEffingham
8.4 out of 10, Very good, (1,000 reviews)
The price is ฿2,986
฿3,314 total
includes taxes & fees
6 Jun - 7 Jun

Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
9.4 out of 10, Exceptional, (1,001 reviews)
The price is ฿4,084
฿4,899 total
includes taxes & fees
7 Jun - 8 Jun

Best Western Delta Inn
Best Western Delta InnEffingham
9.0 out of 10, Wonderful, (1,005 reviews)
The price is ฿3,582
฿4,012 total
includes taxes & fees
25 May - 26 May

Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHGEffingham
9.4 out of 10, Exceptional, (1,004 reviews)
The price is ฿3,888
฿4,354 total
includes taxes & fees
25 May - 26 May

Fairfield Inn & Suites Marriott Effingham
Fairfield Inn & Suites Marriott EffinghamEffingham
9.0 out of 10, Wonderful, (495 reviews)
The price is ฿3,565
฿3,957 total
includes taxes & fees
21 Jun - 22 Jun

Cobblestone Inn & Suites - Altamont
Cobblestone Inn & Suites - AltamontAltamont
9.6 out of 10, Exceptional, (860 reviews)
The price is ฿3,234
฿3,492 total
includes taxes & fees
31 May - 1 Jun

Comfort Inn & Suites Marion I-57
Comfort Inn & Suites Marion I-57Marion
9.4 out of 10, Exceptional, (1,001 reviews)
The price is ฿4,190
฿5,027 total
includes taxes & fees
31 May - 1 Jun

Baymont by Wyndham Effingham
Baymont by Wyndham EffinghamEffingham
8.2 out of 10, Very good, (1,008 reviews)
The price is ฿2,638
฿2,928 total
includes taxes & fees
1 Jun - 2 Jun

The Principal Hotel
The Principal HotelColumbia
9.8 out of 10, Exceptional, (271 reviews)
The price is ฿3,686
฿4,090 total
includes taxes & fees
25 May - 26 May

Best Western Plus Parkside Inn & Suites
Best Western Plus Parkside Inn & SuitesOlney
9.8 out of 10, Exceptional, (345 reviews)
The price is ฿4,138
฿4,592 total
includes taxes & fees
31 May - 1 Jun

Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis O'Fallon, ILO'Fallon
9.6 out of 10, Exceptional, (1,004 reviews)
The price is ฿4,149
฿4,812 total
includes taxes & fees
14 Jun - 15 Jun

Country Inn & Suites by Radisson, Marion, IL
Country Inn & Suites by Radisson, Marion, ILMarion
8.6 out of 10, Excellent, (1,004 reviews)
The price is ฿3,761
฿4,513 total
includes taxes & fees
21 Jun - 22 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southern Illinois
Apartment

Murphysboro Retreat w/ Deck Near Kinkaid Lake!
Murphysboro Retreat w/ Deck Near Kinkaid Lake!Murphysboro
10.0 out of 10, Exceptional, (1 review)
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Photo by Southernmost Illinois Tourism Bureau
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Top Southern Illinois Hotel Reviews

Super 8 by Wyndham Troy IL/St. Louis Area
10/10 Excellent
More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
The price is ฿1,999 per night from 15 Jun to 16 Jun
฿1,999
฿2,299 total
15 Jun - 16 Jun
includes taxes & fees
6.8/10 (1,010 reviews)






























































































