Photo by Southernmost Illinois Tourism Bureau
Find hotels in Southern Illinois, IL from ฿1,824
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Southern Illinois
Check prices for these dates
Our top choices for Southern Illinois hotels
Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHGEffingham
9.4 out of 10, Exceptional, (1,002 reviews)
"Room was clean, staff was very pleasant, breakfast was delicious and plentiful and we were able to enjoy all amenities. "
Laura
The price is ฿3,210
฿3,595 total
includes taxes & fees
28 Feb - 1 Mar
Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
8.8 out of 10, Excellent, (1,002 reviews)
"Clean, friendly staff and good breakfast. Location is excellent. "
Maria
The price is ฿2,776
฿3,081 total
includes taxes & fees
22 Mar - 23 Mar
La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
9.2 out of 10, Wonderful, (1,005 reviews)
"Staff was amazing and the brekfast was good too!"
Kevin
The price is ฿3,014
฿3,376 total
includes taxes & fees
1 Mar - 2 Mar
Innkeeper Motel
Innkeeper MotelHamel
7.0 out of 10, Good, (4 reviews)
"Good value"
ian
The price is ฿1,960
฿2,175 total
includes taxes & fees
23 Feb - 24 Feb
Quality Inn Effingham North
Quality Inn Effingham NorthEffingham
8.4 out of 10, Very good, (1,002 reviews)
"It’s a good place to stay for a reasonable price."
Brenda
The price is ฿2,473
฿2,745 total
includes taxes & fees
8 Mar - 9 Mar
Quality Inn & Suites Vandalia near I-70 and Hwy 51
Quality Inn & Suites Vandalia near I-70 and Hwy 51Vandalia
8.4 out of 10, Very good, (1,001 reviews)
"I always stay at this hotel when visiting! Its updated and the staff is so attentive!"
Anessa
The price is ฿1,955
฿2,131 total
includes taxes & fees
25 Feb - 26 Feb
Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
9.6 out of 10, Exceptional, (1,662 reviews)
"Hotel is very clean, nicely furnished and the beds were so comfy!"
Christina
The price is ฿3,483
฿3,928 total
includes taxes & fees
26 Feb - 27 Feb
Ramada by Wyndham Vandalia
Ramada by Wyndham VandaliaVandalia
7.8 out of 10, Good, (819 reviews)
"The room was clean, the staff was friendly, respectful and very helpful "
Dianna
The price is ฿2,115
฿2,305 total
includes taxes & fees
23 Feb - 24 Feb
Comfort Suites Effingham Central
Comfort Suites Effingham CentralEffingham
8.8 out of 10, Excellent, (586 reviews)
"This hotel is a great value for the price. Friendly staff, clean room, good nights sleep. I emphasize great value!"
Richard
The price is ฿3,021
฿3,382 total
includes taxes & fees
8 Mar - 9 Mar
Best Western Delta Inn
Best Western Delta InnEffingham
9.2 out of 10, Wonderful, (1,010 reviews)
"Staff very friendly!"
C. Mark
The price is ฿2,588
฿2,898 total
includes taxes & fees
8 Mar - 9 Mar
Holiday Inn Express & Suites Vandalia by IHG
Holiday Inn Express & Suites Vandalia by IHGVandalia
8.8 out of 10, Excellent, (791 reviews)
"Clean room & staff was great!"
Lori
The price is ฿3,639
฿3,966 total
includes taxes & fees
1 Mar - 2 Mar
Super 8 by Wyndham Carbondale
Super 8 by Wyndham CarbondaleCarbondale
7.4 out of 10, Good, (1,005 reviews)
"Great place "
Christy
The price is ฿2,022
฿2,325 total
includes taxes & fees
1 Mar - 2 Mar
Holiday Inn Effingham by IHG
Holiday Inn Effingham by IHGEffingham
9.0 out of 10, Wonderful, (663 reviews)
"Nice place with bar and restaurant on site."
Steve
The price is ฿2,837
฿3,176 total
includes taxes & fees
28 Feb - 1 Mar
Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
9.6 out of 10, Exceptional, (713 reviews)
"Very clean, nice hot breakfast, and kind staff. "
Erin
The price is ฿3,881
฿4,307 total
includes taxes & fees
28 Feb - 1 Mar
Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
9.4 out of 10, Exceptional, (1,003 reviews)
"All of the above, enjoyed the evening meal and breakfast, also staff was very friendly.
"
Barbara
The price is ฿3,079
฿3,694 total
includes taxes & fees
13 Mar - 14 Mar
Home2 Suites By Hilton Effingham
Home2 Suites By Hilton EffinghamEffingham
9.8 out of 10, Exceptional, (38 reviews)
"Very kind staff, very clean, very pleased. "
Erin
The price is ฿3,800
฿4,256 total
includes taxes & fees
28 Feb - 1 Mar
Baymont by Wyndham Effingham
Baymont by Wyndham EffinghamEffingham
8.0 out of 10, Very good, (1,004 reviews)
"The hotel location was good, the room was clean, and the staff was kind."
JoAnn
The price is ฿2,221
฿2,465 total
includes taxes & fees
3 Mar - 4 Mar
Ramada by Wyndham Effingham
Ramada by Wyndham EffinghamEffingham
7.6 out of 10, Good, (1,002 reviews)
"Great, friendly staff, nice room, and good breakfast. "
John L
The price is ฿1,924
฿2,154 total
includes taxes & fees
28 Feb - 1 Mar
Days Inn by Wyndham Effingham
Days Inn by Wyndham EffinghamEffingham
6.0 out of 10, (1,001 reviews)
"I liked the entire stay clean room good staff fully complete breakfast with amenities."
Matt
The price is ฿1,719
฿1,924 total
includes taxes & fees
16 Mar - 17 Mar
Best Western U. S. Inn
Best Western U. S. InnNashville
8.6 out of 10, Excellent, (402 reviews)
"Good staff "
Jose Diego
The price is ฿2,737
฿2,983 total
includes taxes & fees
24 Feb - 25 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southern Illinois
Cottage
Cozy Anna Home Near Southern Illinois Attractions!
Cozy Anna Home Near Southern Illinois Attractions!Anna
10.0 out of 10, Exceptional, (1 review)
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Southern Illinois attractions
Learn more about Southern Illinois
Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
Top Southern Illinois Hotel Reviews
Comfort Suites Fairview Heights - St. Louis
10/10 Excellent
More cheap stays in Southern Illinois
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
The price is ฿1,586 per night from 1 Mar to 2 Mar
฿1,586
฿1,824 total
1 Mar - 2 Mar
includes taxes & fees
7/10 Good! (1,005 reviews)
