Southern Illinois Holiday Rentals, Illinois: Private House Rentals

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Our top choices for Southern Illinois hotels

A bar area with a long counter, multiple chairs, and hanging light fixtures.

A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.

A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.

A spacious lobby with a reception desk, seating area, and glass doors leading outside.

1. Drury Plaza Hotel Mt. Vernon

Mount Vernon

Kirstyn

฿3,731

฿4,208 total

includes taxes & fees

1 Nov - 2 Nov

A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and illuminated pillars.

A hotel room with two beds, a large window, and a wall-mounted lamp.

A modern kitchen with a wooden cabinet, coffee maker, and storage shelves.

A buffet with labeled food options including turkey sausage and bacon.

2. Holiday Inn Express & Suites Mount Vernon by IHG

Mount Vernon

John

฿3,840

฿4,328 total

includes taxes & fees

11 Oct - 12 Oct

A hotel lobby with a reception desk, seating area, and a large screen TV.

A hotel room with a marble bathtub, a wooden dining table with chairs, a bed with a headboard, and a nightstand with lamps.

A brick building with a patio area featuring wicker furniture and a table.

A Comfort Suites hotel with a spacious parking lot and a modern brick facade.

3. Comfort Suites Mount Vernon

Mount Vernon

Lori

฿4,112

฿4,631 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a beige sectional sofa, a fireplace, and a view of the outside through large glass doors.

A treats section with a variety of snacks and beverages, including a refrigerated display and shelves stocked with items like Welch's and Bonde.

A modern living area with a sectional sofa, a fireplace, and a flat-screen TV.

A modern hotel lobby with a long dining table, bar stools, a sofa, and a fireplace.

4. Hampton Inn & Suites Effingham

Effingham

Marjorie

฿4,545

฿5,044 total

includes taxes & fees

2 Nov - 3 Nov

A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.

A hotel room with a large bathtub, a desk with a chair, and a bed.

A Fairfield Inn & Suites by Marriott hotel with a parking lot and a clear sky.

A hotel lobby with a reception desk, a red sofa, a potted plant, and a fireplace.

5. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Mount Vernon

Susan

฿3,377

฿3,816 total

includes taxes & fees

17 Oct - 18 Oct

A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.

A hallway with vending machines and a carpeted floor.

6. SureStay Hotel by Best Western Whittington Rend Lake

Whittington

MARK

฿2,874

฿3,189 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with a clear view of the surrounding area, including a seating area with chairs and a view of the outdoors through large windows.

A spacious dining area with a long wooden table, multiple chairs, and pendant lighting.

A hotel room with a desk, two monitors, a keyboard, and a mouse.

A Best Western hotel with a modern facade, a parking lot, and a clear sky.

7. Best Western Delta Inn

Effingham

Susan

฿2,802

฿3,138 total

includes taxes & fees

25 Oct - 26 Oct

A La Quinta hotel with a stone facade, a covered entrance, and a parking lot.

An indoor swimming pool with lounge chairs and a clear view of the pool area.

A modern hotel lobby with a large sun-shaped artwork, multiple seating areas, and a patterned rug.

A hotel room with a large bed, a desk with a chair, a flat-screen TV, a bathtub, and framed pictures on the wall.

8. La Quinta Inn & Suites by Wyndham Effingham

Effingham

Sarah

฿4,000

฿4,480 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a fireplace, a bookshelf, a large wall clock, and a cozy seating area.

A modern living room with a sofa, coffee table, and a dining area with chairs.

A Country Inn & Suites building with a covered entrance and a parking lot.

An indoor swimming pool with clear water, surrounded by white lounge chairs and tables, with a high ceiling and natural light from windows.

9. Country Inn & Suites by Radisson, Marion, IL

Marion

Lisa

฿2,945

฿3,533 total

includes taxes & fees

1 Nov - 2 Nov

A modern indoor pool area with a blue ceiling, large windows, and a pool with a metal ladder.

A modern hotel lobby with a seating area, a reception desk, and a 'Treats' sign in the background.

A modern kitchen with a coffee station, fruit display, and a waffle advertisement.

A snack and treat section with shelves stocked with various snacks, a 'Welcome to our store' sign, and a 'Treats' sign.

10. Hampton Inn O'Fallon

O'Fallon

Edmond

฿3,694

฿4,284 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with high ceilings, multiple seating areas, and large windows allowing natural light.

A spacious lobby with a high ceiling, a central seating area with multiple chairs, a reception desk, and a kitchen area in the background.

An outdoor patio area with a table and chairs, a red umbrella, and a brick building facade.

An indoor swimming pool with clear water, tiled walls, and a ceiling with square vents.

11. Drury Inn & Suites Marion

Marion

Racquelle

฿3,126

฿3,751 total

includes taxes & fees

18 Oct - 19 Oct

A modern breakfast bar with a coffee machine, cereal, and fruit display.

A Holiday Inn Express hotel with a brick facade, large windows, and a covered entrance.

A hotel room with a desk equipped with a desktop computer, a printer, and a keyboard. There are two monitors, a chair, and a framed picture on the wall.

A coffee station with multiple coffee dispensers, a hot water station, and a variety of coffee products on display.

12. Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Marion

Jennifer

฿3,873

฿4,647 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a reception desk, seating area, and a kitchen in the background.

A modern kitchen with a central island, bar stools, and various appliances.

A golf course with a flagstick, trees, and a water hazard.

A hotel room with a bed, bedside table, lamp, desk, chair, and a television.

13. Comfort Inn & Suites Marion I-57

Marion

Michele

฿3,315

฿3,977 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.

An outdoor patio area with tables and chairs, large windows, and red umbrellas.

A hotel room with two beds, a desk, a chair, a TV, and a balcony with a view.

A modern indoor seating area with leather chairs and tables, a central round table, and a staircase leading to an upper level.

14. DoubleTree by Hilton Mt. Vernon

Mount Vernon

Kenneth

฿4,299

฿4,838 total

includes taxes & fees

29 Oct - 30 Oct

A lobby with a blue sofa, a brown leather chair, a round coffee table, and a fireplace.

A gym with treadmills, ellipticals, and a mirrored wall.

A hotel room with a large bed, two bedside lamps, a chair, a mirror, and a framed picture on the wall.

A hotel room with a blue wall, a TV on a wooden shelf, a white curtain, a lamp, a brown sofa, a small round table, and a patterned carpet.

15. Fairfield Inn & Suites Marriott Effingham

Effingham

Jeannette

฿3,543

฿3,932 total

includes taxes & fees

2 Nov - 3 Nov

A banquet hall with tables set for a formal event, draped with white fabric and string lights, and a chandelier above.

A spacious restaurant with high ceilings, large windows, and a variety of seating arrangements including tables and chairs.

A Holiday Inn lobby with a reception desk, two armchairs, and a decorative ceiling light.

16. Holiday Inn Effingham by IHG

Effingham

Penny

฿3,832

฿4,291 total

includes taxes & fees

1 Nov - 2 Nov

A self-service breakfast area with a coffee machine, refrigerated display case, and various food items.

A Best Western hotel with a parking lot and a covered entrance.

A gym with treadmills, ellipticals, and weight machines.

A spacious lobby with a sofa, chairs, a coffee table, and a dining area with tables and chairs.

17. Best Western Marion Hotel

Marion

Cornell

฿2,578

฿3,093 total

includes taxes & fees

25 Oct - 26 Oct

A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

An indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls. There are lounge chairs and a small seating area with tables.

A spacious lobby with a large seating area, a reception desk, and a television.

A modern kitchen with a checkered tile backsplash, wooden flooring, and stainless steel appliances.

18. Best Western Plus Centralia Hotel & Suites

Centralia

Jeremy

฿4,673

฿5,232 total

includes taxes & fees

15 Oct - 16 Oct

A Country Inn & Suites building with a covered entrance and a sign.

A restaurant with wooden tables and chairs, a coffee bar with various appliances, and a TV mounted on the wall.

A hotel room with a large bathtub, a bed with a dark headboard, two bedside tables with lamps, and a mirror above the bathtub.

An indoor swimming pool with clear lane markings, a lifeguard chair, and a no diving sign.

19. Country Inn & Suites by Radisson, Effingham, IL

Effingham

Sonya

฿2,992

฿3,320 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with a fire pit, seating, and a covered section.

A hotel room with a large bed, a sofa, a small table, and a wall-mounted TV.

A store interior with refrigerated beverage dispensers, snack shelves, and a display of ceramics.

A modern gym with various exercise equipment, including dumbbells, benches, and a squat rack.

20. Home2 Suites By Hilton Effingham

Effingham

Steve

฿4,339

฿4,859 total

includes taxes & fees

30 Oct - 31 Oct

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Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

9.8/10 (63 reviews)

See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.

See properties

World Wide Technology Raceway

9.0/10 (2 reviews)

Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

See properties

O'Fallon Family Sports Park

8.6/10 (137 reviews)

This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.

See properties

Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

See all hotels in Southern Illinois

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

10/10 Excellent

"Excellent facility and staff."

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent

"Great stay"

Comfort Suites Mount Vernon

8/10 Good

"The front desk staff Kim is very helpful and accommodating, she’s a hard worker too, we had good service from Kim"

Drury Inn & Suites Marion

8/10 Good

"friendly and helpful staff. Great food with many options to choose from. Great hot tub"

Comfort Inn Edwardsville - St. Louis

10/10 Excellent

"Nice location."

Quality Inn & Suites Metropolis I-24

8/10 Good

"Motel is close to the interstate and has a bar and grill next door. Staff was very pleasant and helpful. Lobby and room were clean and neat. The hallway to the room had a musty mildew smell to it. Shower pressure was adequate but weak. TV and Air conditioning were both working well."

Country Inn & Suites by Radisson, Marion, IL

10/10 Excellent

"This is an excellent hotel to stay at. Updated, easy parking, staff is very friendly, breakfast is great, will stay at this hotel again."

More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL

฿1,772

฿2,037 total

5 Nov - 6 Nov

includes taxes & fees

Americas Best Value Inn Collinsville St. Louis

552 Ramada Blvd Collinsville IL

฿1,773

฿2,038 total

18 Oct - 19 Oct

includes taxes & fees

Quality Inn & Suites Metropolis I-24

2118 E 5th St Metropolis IL

฿1,945

฿2,260 total

1 Nov - 2 Nov

includes taxes & fees

7.6/10 Good! (1,000 reviews)

Baymont by Wyndham Effingham

1811 W Fayette Avenue Effingham IL

฿2,433

฿2,701 total

18 Oct - 19 Oct

includes taxes & fees

Country Inn & Suites by Radisson, Effingham, IL

1200 N Raney Effingham IL

฿2,992

฿3,320 total

1 Nov - 2 Nov

includes taxes & fees

8.8/10 Excellent! (1,003 reviews)

Baymont by Wyndham Marion

2608 W Main St Marion IL

฿2,874

฿3,449 total

11 Oct - 12 Oct

includes taxes & fees

8.4/10 Very good! (1,074 reviews)

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Book Hotels in Southern Illinois on Expedia.com

Find hotels in Southern Illinois, IL from ฿2,037

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southern Illinois

Check prices for these dates

Filter by

Star rating

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Our top choices for Southern Illinois hotels

1. Drury Plaza Hotel Mt. Vernon

2. Holiday Inn Express & Suites Mount Vernon by IHG

3. Comfort Suites Mount Vernon

4. Hampton Inn & Suites Effingham

5. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

6. SureStay Hotel by Best Western Whittington Rend Lake

7. Best Western Delta Inn

8. La Quinta Inn & Suites by Wyndham Effingham

9. Country Inn & Suites by Radisson, Marion, IL

10. Hampton Inn O'Fallon

11. Drury Inn & Suites Marion

12. Holiday Inn Express Hotel & Suites Marion Northeast by IHG

13. Comfort Inn & Suites Marion I-57

14. DoubleTree by Hilton Mt. Vernon

15. Fairfield Inn & Suites Marriott Effingham

16. Holiday Inn Effingham by IHG

17. Best Western Marion Hotel

18. Best Western Plus Centralia Hotel & Suites

19. Country Inn & Suites by Radisson, Effingham, IL

20. Home2 Suites By Hilton Effingham

Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

World Wide Technology Raceway

O'Fallon Family Sports Park

Learn more about Southern Illinois

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Inn & Suites St. Louis O'Fallon, IL

Comfort Suites Mount Vernon

Drury Inn & Suites Marion

Comfort Inn Edwardsville - St. Louis

Quality Inn & Suites Metropolis I-24

Country Inn & Suites by Radisson, Marion, IL

More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon

Americas Best Value Inn Collinsville St. Louis

Quality Inn & Suites Metropolis I-24

Baymont by Wyndham Effingham

Country Inn & Suites by Radisson, Effingham, IL

Baymont by Wyndham Marion

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