The Best Hotels in Skyline, San Diego - 2026 Updated Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Where to stay in Skyline

Find the best Skyline areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

See properties

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

See properties

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

See properties

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

See properties

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

See properties

Top Skyline Hotel Reviews

Wyndham San Diego Bayside

10/10 Excellent

"We recommend staying here. The location is great, near the water and a couple popular tourist sites, and within walking distance of Little Italy. The staff were friendly and helpful, and rooms were very comfortable. Also a good fairly central location if you’re driving. I’m sure we’ll be back!"

Days Inn by Wyndham San Diego Hotel Circle

6/10 Okay

"The hotel is clean, bed sheets towels. The shower felt like it was going to fall thru the floor. You can hear upper floor people walking and creaking noises. It was creaking alot. Again clean room but not really updated.. the pool area was decent. Heated pool too. If you just want a decent stay. Then it's fine."

Sheraton San Diego Resort

10/10 Excellent

"Awesome resort!! Just a beautiful venue! Every room is modern and most of them have incredible views. The resort is family oriented but not too kid oriented, I say that with best intentions because kids will have a good time. Great for crowds under 21 and over 35. Two restaurants with three bars. The margarita bar is great, and the brewery bar has a great selection. You can order drinks pool side as well, and there’s another bar right by it. $10/night parking is across the street, otherwise you’ll be paying significantly more for on-site or valet. Drop off and pay a tip a bell hop nicely instead. The staff is extremely pleasant and helpful. I don’t remember if I’ve stayed at a hotel where the staff was this happy, it really adds to the environment. The location is a little out of the way being by the airport but the drive is not bad to either downtown or La Jolla. The good thing about the location being away from downtown is that it does make the Sheraton feel a bit more exclusive. Plus if you get a room that faces the city, the skyline and Coronado bridge at night is quite a treat. I think I’ll be staying there again soon and would recommend to friends in the area that it’s an ideal spot for a stay-cation."

Hard Rock Hotel San Diego

6/10 Okay

"first I bought 2 suites for my daughter's graduation. then on arrival they separated us to two different sides of hotel. one room with balcony faced all the air conditioning on top of joining building. disgusting view with loud units. The furniture has stains and wear. the sliding bath door was hanging at end not properly closing. It had water damage at edge. water pressure in one room would only go hot. The pool being at a Hardrock was only 4 ft deep and small. ( they throw pool parties there) Very little arrival parking area. The tile is delaminating from concrete throughout the hotel. loose tiles. I felt ripped off for money we spent on 2 rooms. As for the area. can't go a block with crazy amount of homeless which some harassed my daughter and boyfriend. stunk like pee everywhere . San Diego is letting down its tourists and residents big-time. so much I won't go back. dirty city. the next LA"

Frequently asked questions

What's it like in Skyline?

Travellers will be sure to find plenty to entertain them in San Diego's Skyline neighbourhood.

If I need to cancel my hotel reservation in Skyline, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the top deals on offer in Skyline.

What can I see and do in this San Diego neighbourhood?

A few places to visit in the area around Skyline include Malcolm X Library and Performing Arts Center, Tubman-Chavez Center and Bonita Golf Club. While you're out sightseeing in San Diego, make sure that you visit other sights such as Sweetwater Summit Regional Park or San Diego Voice & Viewpoint.

Explore a world of travel with Expedia

More ways to book

Book Hotels in Skyline on Expedia.com

Search Hotels in Skyline, San Diego

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Our top choices for Skyline hotels

Ayres Lodge Alpine

Sycuan Casino Resort

Ramada by Wyndham San Diego Poway Miramar

Best Western Americana Inn

Days Inn by Wyndham San Diego-East/El Cajon

Pleasant Inn

Comfort Inn Chula Vista San Diego South

La Quinta Inn by Wyndham San Diego Chula Vista

Wyndham Garden San Diego Near SeaWorld

The Alcala Hotel Mission Valley/Seaworld

California Suites Hotel

Kings Inn San Diego

Hotel Palmeras Chula Vista

Best Western San Diego/Miramar Hotel

GreenTree Inn San Diego Mission Bay

The Rambler Hotel

Heritage Inn San Diego

Best Western Plus Marina Gateway Hotel

The Atwood Hotel San Diego - SeaWorld/Zoo

Handlery Hotel

Where to stay in Skyline

Downtown San Diego

Pacific Beach

Mission Beach

Gaslamp Quarter

Mission Bay

Top Skyline Hotel Reviews

Wyndham San Diego Bayside

Frequently asked questions

Explore a world of travel with Expedia