Search Hotels in Siesta Isle, Fort Myers Beach

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Siesta Isle hotels

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
8.8 out of 10, Excellent, (1,001 reviews)
"Great stay"
United States
Andrea
The price is ฿7,568
฿8,438 total
includes taxes & fees
7 Mar - 8 Mar
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
21.1 km from Siesta Isle
9.6 out of 10, Exceptional, (230 reviews)
"Beautiful resort, great communication, super clean "
United States
Ronald
The price is ฿3,141
฿5,625 total
includes taxes & fees
1 Mar - 2 Mar
Matlacha on Shoreview

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
3.0 star property
21.4 km from Siesta Isle
9.4 out of 10, Exceptional, (766 reviews)
"Stayed there several times, for different functions in town. Always nice, clean rooms, and friendly staff. "
United States
Clifton
The price is ฿6,854
฿7,642 total
includes taxes & fees
8 Feb - 9 Feb
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
8.3 km from Siesta Isle
9.0 out of 10, Wonderful, (1,001 reviews)
"Amazing room and view. Great place to stay/vacation. Would come back over and over again. "
United States
Frank
The price is ฿7,664
฿9,814 total
includes taxes & fees
8 Feb - 9 Feb
The Westin Cape Coral Resort At Marina Village

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
9.5 km from Siesta Isle
8.8 out of 10, Excellent, (1,226 reviews)
"Nice room, great tiki bar and pool area, and friendly staff."
United States
Jason
The price is ฿5,223
฿5,824 total
includes taxes & fees
7 Mar - 8 Mar
Dolphin Key Resort

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
9.9 km from Siesta Isle
8.8 out of 10, Excellent, (1,000 reviews)
"Room was clean and staff was fantastic "
United States
Wayne
The price is ฿5,225
฿5,826 total
includes taxes & fees
8 Feb - 9 Feb
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
9.7 km from Siesta Isle
9.2 out of 10, Wonderful, (1,205 reviews)
"Is great place to stay."
United States
Anastassia
The price is ฿4,569
฿5,095 total
includes taxes & fees
8 Feb - 9 Feb
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

The Perry Hotel Naples

The Perry Hotel Naples
4.5 star property
26.4 km from Siesta Isle
9.6 out of 10, Exceptional, (616 reviews)
"Friendly, helpful staff Great location excellent restaurant"
United States
Alan
The price is ฿8,862
฿11,422 total
includes taxes & fees
8 Feb - 9 Feb
The Perry Hotel Naples

Innovation Hotel

Innovation Hotel
4.0 star property
28.2 km from Siesta Isle
9.8 out of 10, Exceptional, (563 reviews)
"This is an excellent hotel, everything is perfect "
United States
Gustavo
The price is ฿14,566
฿16,168 total
includes taxes & fees
18 Feb - 19 Feb
Innovation Hotel

Inn at Pelican Bay

Inn at Pelican Bay
4.0 star property
29.2 km from Siesta Isle
9.6 out of 10, Exceptional, (1,003 reviews)
"Beautiful Inn. Not as close to the beach as I expected."
United States
Lisa
The price is ฿14,250
฿17,719 total
includes taxes & fees
1 Mar - 2 Mar
Inn at Pelican Bay

Fairways Inn of Naples

Fairways Inn of Naples
3.0 star property
28.6 km from Siesta Isle
9.4 out of 10, Exceptional, (1,196 reviews)
"Clean room and nice staff"
United States
Julian
The price is ฿6,000
฿6,660 total
includes taxes & fees
8 Mar - 9 Mar
Fairways Inn of Naples

SpringHill Suites by Marriott Fort Myers Estero

SpringHill Suites by Marriott Fort Myers Estero
2.5 star property
17.9 km from Siesta Isle
9.2 out of 10, Wonderful, (838 reviews)
"Great breakfast and nice clean room"
Canada
John
The price is ฿6,409
฿7,305 total
includes taxes & fees
22 Feb - 23 Feb
SpringHill Suites by Marriott Fort Myers Estero

DoubleTree Suites by Hilton Naples

DoubleTree Suites by Hilton Naples
4.0 star property
26.4 km from Siesta Isle
9.2 out of 10, Wonderful, (1,002 reviews)
"We stay here every year and are never disappointed!"
United States
Alyssa
The price is ฿10,747
฿11,929 total
includes taxes & fees
7 Feb - 8 Feb
DoubleTree Suites by Hilton Naples

Embassy Suites by Hilton Fort Myers Estero

Embassy Suites by Hilton Fort Myers Estero
3.5 star property
18 km from Siesta Isle
9.2 out of 10, Wonderful, (1,104 reviews)
"Convenient location, quiet room, good breakfast. "
United States
Jeff
The price is ฿6,920
฿7,715 total
includes taxes & fees
8 Feb - 9 Feb
Embassy Suites by Hilton Fort Myers Estero

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
10.1 km from Siesta Isle
9.2 out of 10, Wonderful, (1,586 reviews)
"Sweet staff, amazing beach access, pool, restaurant on site. Good value and great stay!"
United States
Freda
The price is ฿12,343
฿14,556 total
includes taxes & fees
9 Feb - 10 Feb
Sanibel Island Beach Resort

TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero
3.5 star property
17.2 km from Siesta Isle
9.4 out of 10, Exceptional, (486 reviews)
"The staff was very accommodating. The location was wonderful, off the main roads but close to everything. I will definitely recommend to others and also stay there again."
United States
Susan
The price is ฿7,507
฿8,371 total
includes taxes & fees
8 Mar - 9 Mar
TownePlace Suites by Marriott Fort Myers Estero

Drury Inn & Suites Fort Myers Airport FGCU

Drury Inn & Suites Fort Myers Airport FGCU
3.0 star property
16.5 km from Siesta Isle
9.8 out of 10, Exceptional, (1,000 reviews)
"Always a great stay"
United States
David
The price is ฿6,268
฿6,988 total
includes taxes & fees
9 Feb - 10 Feb
Drury Inn & Suites Fort Myers Airport FGCU

Hampton Inn & Suites Fort Myers-Estero/FGCU

Hampton Inn & Suites Fort Myers-Estero/FGCU
2.5 star property
18.2 km from Siesta Isle
9.2 out of 10, Wonderful, (1,002 reviews)
"The hotel was everything we were looking for and the staff were super helpful and friendly."
United States
Nancy
The price is ฿6,218
฿6,934 total
includes taxes & fees
9 Feb - 10 Feb
Hampton Inn & Suites Fort Myers-Estero/FGCU

Comfort Suites Fort Myers East I-75

Comfort Suites Fort Myers East I-75
2.5 star property
25.5 km from Siesta Isle
9.6 out of 10, Exceptional, (396 reviews)
"Good hotel for the price "
United Kingdom
Paul
The price is ฿4,019
฿4,481 total
includes taxes & fees
15 Feb - 16 Feb
Comfort Suites Fort Myers East I-75

Island Inn

Island Inn
3.5 star property
15 km from Siesta Isle
9.4 out of 10, Exceptional, (1,127 reviews)
"Everything was wonderful."
United States
Walter
The price is ฿12,343
฿13,762 total
includes taxes & fees
8 Feb - 9 Feb
Island Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Siesta Isle

Find the best Siesta Isle areas for the activities you enjoy most.

Mid Island

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

South Island

While visiting South Island, you might make a stop by sights like Santini Marina Shopping Plaza and Castle Beach.

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

Laguna Shores

While Laguna Shores may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lover's Key Beach and Santini Marina Shopping Plaza.

Top Siesta Isle Hotel Reviews

Frequently asked questions

What is Siesta Isle like?
Travellers will be sure to find plenty to entertain them in Fort Myers Beach's Siesta Isle neighbourhood. Consider a visit to San Carlos Bay - Bunche Beach Preserve as part of your Siesta Isle travel plans.
Where is the best place to stay in Siesta Isle?
Based on Expedia customer reviews, Latitude 26 Waterfront Boutique Resort - Fort Myers Beach is the highest ranked property in Siesta Isle. This hotel offers a marina and free breakfast.
How many hotels will I find in the Siesta Isle area?
When you want to put your feet up after a day of exploring the sights in Fort Myers Beach, you can choose from 18 Expedia hotels and other accommodation options in Siesta Isle.
If I need to cancel my hotel reservation in Siesta Isle, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the best deals in Siesta Isle.
What are the top things to see and do in Siesta Isle?
San Carlos Bay - Bunche Beach Preserve is an attraction you might want to check out while you're in Siesta Isle. Key West Express and Bunche Beach are also worth a visit when you're out sightseeing in Fort Myers Beach.