A coastal landscape with a wooden deck, lush green foliage, and a view of the ocean under a cloudy sky.

Find hotels in Santana from ฿1,718

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
27 Aug - 28 Aug
Tomorrow
28 Aug - 29 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sep - 6 Sep

Filter by

Star rating

Guest rating

Our top choices for Santana hotels

1. Roça Santo António Ecolodge Hotel

Roça Santo António Ecolodge Hotel
Santana
Germany
Daniel
฿4,008
฿7,662 total
includes taxes & fees
5 Sept - 6 Sept
Roça Santo António Ecolodge Hotel

2. Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection
São Tomé
United Kingdom
Kysha
฿5,777
฿6,804 total
includes taxes & fees
8 Sept - 9 Sept
Omali São Tomé – Principe Collection

3. Pestana São Tomé

Pestana São Tomé
Vila Maria
Canada
alexander
฿9,559
฿10,993 total
includes taxes & fees
1 Sept - 2 Sept
Pestana São Tomé

4. SH Boutique Hotel

SH Boutique Hotel
São Tomé
United States
Simon Peter
฿1,944
฿2,236 total
includes taxes & fees
28 Aug - 29 Aug
SH Boutique Hotel

5. Agua Leve

Agua Leve
São Tomé
฿1,643
฿1,889 total
includes taxes & fees
3 Sept - 4 Sept
Agua Leve

6. Hotel Kenito

Hotel Kenito
São Tomé
United States
Ada
฿2,659
฿3,057 total
includes taxes & fees
1 Sept - 2 Sept
Hotel Kenito

7. Guest House Quinta Natural

Guest House Quinta Natural
Trindade
฿1,211
฿1,921 total
includes taxes & fees
28 Aug - 29 Aug
Guest House Quinta Natural

8. Emoyeni Gardens Hotel

Emoyeni Gardens Hotel
Vila Maria
฿5,067
฿5,827 total
includes taxes & fees
31 Aug - 1 Sept
Emoyeni Gardens Hotel

9. Casa de Ferias

Casa de Ferias
São Tomé
Sweden
Lars Roland
฿622
฿2,405 total
includes taxes & fees
26 Sept - 27 Sept
Casa de Ferias

10. Hotel Central

Hotel Central
São Tomé
Ireland
Mohammad
฿1,650
฿1,898 total
includes taxes & fees
11 Sept - 12 Sept
Hotel Central

11. Welfare Agroturismo

Welfare Agroturismo
Trindade
฿2,543
฿2,924 total
includes taxes & fees
28 Aug - 29 Aug
Welfare Agroturismo

12. Hotel Praia

Hotel Praia
São Tomé
United States
Jonathan
฿4,705
฿5,411 total
includes taxes & fees
28 Aug - 29 Aug
Hotel Praia

13. Miramar São Tomé

Miramar São Tomé
São Tomé
United States
sandra
฿5,642
฿6,488 total
includes taxes & fees
30 Aug - 31 Aug
Miramar São Tomé

14. Praia Accommodation

Praia Accommodation
São Tomé
United States
Daniel
฿3,771
฿4,336 total
includes taxes & fees
11 Sept - 12 Sept
Praia Accommodation

15. Alojamento Santos Silva

Alojamento Santos Silva
São Tomé
฿10,455
฿12,023 total
includes taxes & fees
28 Aug - 29 Aug
Alojamento Santos Silva

16. Mucumbli Hotel

Mucumbli Hotel
Neves
Norway
Morten
฿4,662
฿5,361 total
includes taxes & fees
28 Aug - 29 Aug
Mucumbli Hotel

17. Residencial Aeroporto

Residencial Aeroporto
São Tomé
฿2,102
฿2,418 total
includes taxes & fees
28 Aug - 29 Aug
Residencial Aeroporto

18. Residêncial Tamarindos

Residêncial Tamarindos
Guadalupe
United Kingdom
Maria
฿1,494
฿1,718 total
includes taxes & fees
29 Aug - 30 Aug
Residêncial Tamarindos

19. CAMPISMO PRAIA GRANDE

CAMPISMO PRAIA GRANDE
Malanza
United Kingdom
John
฿1,613
฿1,855 total
includes taxes & fees
28 Aug - 29 Aug
CAMPISMO PRAIA GRANDE

20. Nour Apartments

Nour Apartments
São Tomé
฿1,613
฿1,855 total
includes taxes & fees
28 Aug - 29 Aug
Nour Apartments
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Santana

Head to Estadio Nacional 12 de Julho and São Sebastião Museum—just two of the sights around Santana.

See all hotels in Santana
A wooden bench overlooking a calm sea with a small island in the distance and lush greenery on the right.
Photo by Fabrice Récalt

Top Santana Hotel Reviews

More cheap stays in Santana

Nour Apartments

Nour Apartments

Rua 3 de Fevereiro São Tomé
฿1,613
฿1,855 total
28 Aug - 29 Aug
includes taxes & fees
Nour Apartments
Hotel Kenito

Hotel Kenito

Campo de Milho São Tomé
฿2,659
฿3,057 total
1 Sept - 2 Sept
includes taxes & fees
Hotel Kenito
Praia Inhame Eco-Lodge

Praia Inhame Eco-Lodge

Porto Alegre 64 Malanza
฿2,778
฿3,194 total
27 Sept - 28 Sept
includes taxes & fees
8.8/10 Excellent! (27 reviews)
Praia Inhame Eco-Lodge
Sweet Guest House

Sweet Guest House

Vila Dolores n. 087 São Tomé
Get ratesSweet Guest House
Inviting 10 Bed Apartment in Sao Tome

Inviting 10 Bed Apartment in Sao Tome

Avenida Marginal 12 de Julho São Tomé São Tomé
Get ratesInviting 10 Bed Apartment in Sao Tome
Pousada Roça São João dos Angolares

Pousada Roça São João dos Angolares

Cidade dos Angolares São João dos Angolares Sao Tome
Get ratesPousada Roça São João dos Angolares

Frequently asked questions

Where is the best place to stay in Santana?
Based on our traveller data, Roça Santo António Ecolodge Hotel is one of the top choices for your stay. This hotel offers free breakfast and a restaurant. Pool and Beach Villa in Santana is another good choice for your visit. See all available top hotels, or vacation rentals in Santana.
What are some of the best holiday rentals that Santana has to offer?
Alojamento Santos Silva: This holiday home rental outside of Santana offers an outdoor pool, a garden and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include an oven, a microwave and kitchenware. See all vacation rentals in Santana.
If I need to cancel my hotel reservation in Santana, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santana.
What's the best family accommodation in Santana?
Roça Santo António Ecolodge Hotel is a hotel with a children's pool and a restaurant, and it's a top choice on Expedia for families. Also, attractions in the area such as Cloçon Téla Chocolate Factory are fun for the whole family. Find more child-friendly accommodations in Santana.
What are some accommodation options with pools in Santana?
Roça Santo António Ecolodge Hotel is a top hotel with a children's pool, an outdoor pool and free buffet breakfast. View all hotels with pools in Santana.
How is it to stay in Santana?
Those travelling to Santana will definitely enjoy the sights to see and things to do. In Santana, there are 4 hotels and other accommodation options to choose from. Find out more about Santana.
What are the top places to visit in Santana?
Places to visit in the wider area include Estadio Nacional 12 de Julho, São Sebastião Museum and São Nicolau Waterfall. You'll also find Pico São Tomé and Cloçon Téla Chocolate Factory in the area. Take a look at what more there is to see and do in Expedia's Santana guide.
What's the weather like in Santana?
The hottest months are usually March and April, with an average temperature of 28°C, while the coldest months are July and August, with an average of 25°C. The rainiest months in Santana are November, October, December and April, with each month seeing an average of 249 mm of rainfall.