Find hotels in Santa Isabel from ฿3,816

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Our top choices for Santa Isabel hotels

Hacienda del Sur

Hacienda del Sur
2.0 star property
Santa Isabel
9.6 out of 10, Exceptional, (20)
"Is a beautiful place and the staff Rosie is a plus. "
United States
ivette
The price is ฿2,835
฿4,786 total
includes taxes & fees
22 Jan - 23 Jan 2026
Hacienda del Sur

Hotel Las Vegas

Hotel Las Vegas
3.0 star property
Santa Isabel
8.0 out of 10, Very good, (313)
"Excellent"
United States
Noel
Hotel Las Vegas

Aibonito Hotel 206

Aibonito Hotel 206
3.0 star property
Aibonito
6.4 out of 10, (41)
"There was a note left in the room to request tip and again the water was still cold "
United States
Jose
The price is ฿3,888
฿4,160 total
includes taxes & fees
24 Jan - 25 Jan 2026
Aibonito Hotel 206

Hotel El Eden

Hotel El Eden
3.0 star property
Juana Diaz
8.6 out of 10, Excellent, (572)
"Nice place"
United States
Sandra
Hotel El Eden

1912 Boutique Hotel

1912 Boutique Hotel
2.0 star property
Cayey
9.6 out of 10, Exceptional, (29)
"The room are amazing the staff is very attentive and the location is perfect. "
United States
Estiven
The price is ฿5,291
฿5,767 total
includes taxes & fees
7 Jan - 8 Jan 2026
1912 Boutique Hotel

Aibonito Hotel 205

Aibonito Hotel 205
3.0 star property
Aibonito
7.6 out of 10, Good, (21)
"The shareable space it kept nice, clean & well decorated. The room we had was clean as well. "
United States
Hector
The price is ฿4,513
฿4,829 total
includes taxes & fees
26 Dec - 27 Dec
Aibonito Hotel 205

The Place at the Sea

The Place at the Sea
2.0 star property
Ponce
9.2 out of 10, Wonderful, (216)
"Everything was excellent, rooms super clean, friendly staff. Great location right by the beach. Will definitely stay on our next vacations."
United States
Ednardo
The Place at the Sea

Hotel Nuevo Mejico

Hotel Nuevo Mejico
3.5 star property
Ponce
8.0 out of 10, Very good, (707)
"Excellent and very clean! Will stay again when we visit."
United States
Blaise
Hotel Nuevo Mejico

Spark by Hilton Ponce

Spark by Hilton Ponce
3.5 star property
Ponce
8.6 out of 10, Excellent, (1620)
"The staff were very friendly, excellent service, and good food."
United States
lismauby
The price is ฿4,343
฿4,734 total
includes taxes & fees
19 Jan - 20 Jan 2026
Spark by Hilton Ponce

Holiday Inn Ponce & Tropical Casino by IHG

Holiday Inn Ponce & Tropical Casino by IHG
3.5 star property
Ponce
8.8 out of 10, Excellent, (1002)
"Staying at this location felt like home away from home! "
United States
Kimora
The price is ฿4,451
฿4,940 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Ponce & Tropical Casino by IHG

Solace by the Sea

Solace by the Sea
3.0 star property
Ponce
6.2 out of 10, (1000)
"It was ok"
United States
Luz
Solace by the Sea

Meliá Century Hotel Ponce

Meliá Century Hotel Ponce
3.5 star property
Ponce Centro
6.6 out of 10, (1005)
"Staff was very personable and helpful, parking in a crowded downtown area was a huge plus, historic building and great location for local sightseeing."
United States
Gerald
The price is ฿3,993
฿4,353 total
includes taxes & fees
4 Jan - 5 Jan 2026
Meliá Century Hotel Ponce

Aloft Ponce Hotel & Casino

Aloft Ponce Hotel & Casino
3.5 star property
Ponce
8.6 out of 10, Excellent, (1052)
"Clean room, great staff, & great amenities available"
United States
Vanessa
The price is ฿5,571
฿6,184 total
includes taxes & fees
5 Jan - 6 Jan 2026
Aloft Ponce Hotel & Casino

Hilton Ponce Golf & Casino Resort

Hilton Ponce Golf & Casino Resort
4.5 star property
Ponce
8.8 out of 10, Excellent, (1014)
"Food and drinks were great!"
United States
Carlos
The price is ฿7,127
฿7,911 total
includes taxes & fees
25 Dec - 26 Dec
Hilton Ponce Golf & Casino Resort

Ponce Plaza Hotel & Casino

Ponce Plaza Hotel & Casino
3.5 star property
Ponce Centro
9.0 out of 10, Wonderful, (1009)
"Location and great parking"
United States
Roberto A.
Ponce Plaza Hotel & Casino

The Fox Hotel

The Fox Hotel
3.5 star property
Ponce Centro
7.4 out of 10, Good, (983)
"Very nice Hotel, clean and great design."
United States
Bethzaida
The price is ฿3,501
฿3,816 total
includes taxes & fees
11 Jan - 12 Jan 2026
The Fox Hotel

Hotel Vista Bahia & Marina

Hotel Vista Bahia & Marina
3.0 star property
Salinas
8.8 out of 10, Excellent, (30)
"Great stay clean rooms had a lot of amenities to decompress"
United States
Victor
The price is ฿4,513
฿5,074 total
includes taxes & fees
25 Dec - 26 Dec
Hotel Vista Bahia & Marina

Playa Apartments

Playa Apartments
2.5 star property
Salinas
7.6 out of 10, Good, (36)
"Definitely clean, safe, user friendly place"
United States
JULIO
The price is ฿3,927
฿4,791 total
includes taxes & fees
1 Jan - 2 Jan 2026
Playa Apartments

Gladiolas 1207

Gladiolas 1207
3.0 star property
Ponce Centro
6.8 out of 10, (6)
"The property was great; the only thing is we wanted was a broom and mop. But everything else was exceptional !"
United States
Javier
The price is ฿4,980
฿6,161 total
includes taxes & fees
7 Jan - 8 Jan 2026
Gladiolas 1207

La Gozadera Park

La Gozadera Park
1.0 star property
Salinas
The price is ฿4,666
฿5,086 total
includes taxes & fees
23 Jan - 24 Jan 2026
La Gozadera Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Escape to romantic Santa Isabel! Enjoy its dining and beaches.

Aerial view of Wind Turbines in the windfarm of Santa Isabel, Puerto Rico

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Frequently asked questions

What's the best place to stay in Santa Isabel?
Hacienda del Sur is ranked highly by Expedia customers. This hotel offers an outdoor pool and free parking. Another favourite option for your stay based on reviews is Hotel Las Vegas. See all available top hotels, or vacation rentals in Santa Isabel.
If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?
Yes, most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.
What's the best dog-friendly hotel in Santa Isabel?
Hotel Las Vegas is a top dog-friendly option for your stay. See more pet-friendly hotel accommodations in Santa Isabel.
What are some hotels with pools in Santa Isabel?
Hacienda del Sur: Offers free self parking, an outdoor pool and complimentary wireless Internet access. Hilton Ponce Golf & Casino Resort and Aloft Ponce Hotel & Casino are a couple of other choices that feature an on-site pool. View all hotels with pools in Santa Isabel.
What is staying in Santa Isabel like?
Visitors can enjoy all that Santa Isabel has to offer, including the shopping, restaurants and beaches. In Santa Isabel, there are 19 hotels and other accommodation options to choose from. Find out more about Santa Isabel.
What are the top places to visit in Santa Isabel?
A favourite place to visit is Carribbean Cinemas Santa Isabel. You'll also find Playa La Ochenta and Coamo Springs in the area. Take a look at what more there is to see and do in Expedia's Santa Isabel guide.
What's the seasonal weather in Santa Isabel?
The hottest months are usually August and July, with an average temperature of 27°C, while the coldest months are February and March, with an average of 25°C. Average annual precipitation for Santa Isabel is 911 mm.