Santa Fe Holiday Rentals, Alachua: Private House Rentals

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Our top choices for Santa Fe hotels

A spacious indoor dining area with multiple tables and chairs, large windows offering a view of palm trees and greenery outside.

A Holiday Inn Express & Suites hotel with a modern design, multiple floors, and a parking lot.

A modern office space with a reception desk, several chairs, a large window, and a colorful abstract painting on the wall.

A lobby with a patterned carpet, two green armchairs, a white sofa, a small round table with a plant, and framed artwork on the wall.

1. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Alachua

Austin

฿3,495

฿3,932 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen area with a central counter, various food stations, and a chalkboard menu.

A reception desk with a "Welcome to the Sun Shine State" sign, a "Treats" sign, and a minibar area with a "Hilton" sign.

A hotel room with two beds, a desk, a chair, a TV, and a couch.

2. Hampton Inn & Suites Alachua I-75

Alachua

Duane

฿3,513

฿3,952 total

includes taxes & fees

10 Nov - 11 Nov

A large, multi-story hotel with a central courtyard, palm trees, and an American flag.

A spacious dining area with multiple tables and chairs, a kitchen area with a coffee station, and large windows allowing natural light.

A living room with a brown leather sofa, a glass-top coffee table, and a framed picture on the wall.

A bar area with wooden chairs, a bar counter, and a television mounted on the wall.

3. Best Western Gateway Grand

Gainesville

Diane

฿2,841

฿3,196 total

includes taxes & fees

2 Nov - 3 Nov

A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a well-maintained outdoor area with a parking lot.

A modern kitchen with blue-tiled walls, stainless steel appliances, and a central island.

A modern lounge area with a flat-screen TV, a fireplace, teal and brown seating, patterned carpet, and a wall-mounted clock.

A hotel lobby with a seating area featuring sofas and armchairs, a central coffee table, and a flat-screen TV mounted on the wall.

4. La Quinta by Wyndham Gainesville

Gainesville

Edwin

฿3,327

฿3,742 total

includes taxes & fees

25 Oct - 26 Oct

A modern bar area with a long counter, green bar stools, and a television displaying a golf game.

A modern kitchen with a central island, bar stools, pendant lighting, and a dining area with a sofa and chairs.

A Fairfield Inn & Suites Marriott hotel with a modern entrance, multiple floors, and a parking lot.

A modern hotel room with a large bed, a desk, a chair, and a TV mounted on the wall.

5. Fairfield Inn & Suites by Marriott Gainesville I-75

Gainesville

Robert

฿3,999

฿4,498 total

includes taxes & fees

8 Nov - 9 Nov

A cozy restaurant with wooden beams, yellow walls, and a bar area with coffee machines.

A spacious lobby with a dining area, a kitchen, and a large window providing a view of the outdoors.

A reception desk with a sign reading "Quality by Choice Hotels," surrounded by various reptile decorations.

A swimming pool with lounge chairs and umbrellas, a covered seating area, and a multi-story building with balconies.

6. Quality Inn Alachua - Gainesville Area

Alachua

Ivelisse

฿2,446

฿2,752 total

includes taxes & fees

22 Nov - 23 Nov

A modern interior with a staircase, a seating area, and a colorful abstract wall design.

A rooftop pool area with lounge chairs, a small table, and a fire pit.

A modern hotel lobby with a round table featuring two drinks, a sofa, and a colorful wall art piece.

A spacious lobby with modern furniture, large windows, and a colorful abstract wall.

7. Hyatt Place Gainesville Downtown

Downtown Gainesville

Brendon

฿3,293

฿3,705 total

includes taxes & fees

2 Nov - 3 Nov

A modern living room with a fireplace, comfortable seating, a flat-screen TV, and a large window.

A modern hotel lobby with a reception desk, seating area with chairs and ottomans, a large artwork, and a corridor leading to other rooms.

A modern hotel lobby with a long dining table, multiple seating areas, and a large window with curtains.

A fire pit area surrounded by stone tiles, with a metal fence in the background.

8. Comfort Suites Gainesville near University

Gainesville

Maricarmen

฿2,819

฿3,272 total

includes taxes & fees

22 Nov - 23 Nov

A multi-story hotel with a central entrance, palm trees, and a clear sky.

A spacious hotel lobby with a modern staircase, a seating area with a sofa and chairs, and a dining area in the background.

A hotel room with a wooden floor, a red armchair, a beige sofa, a TV, and framed artwork on the wall.

A modern living room with a green sofa, a round coffee table, and a fireplace.

9. Country Inn & Suites by Radisson, Gainesville, FL

Gainesville

Tricia

฿2,970

฿3,342 total

includes taxes & fees

15 Nov - 16 Nov

An outdoor patio with wicker furniture, stone walls, and a barbecue grill.

A modern dining area with a wooden table, blue upholstered chairs, and pendant lighting.

A modern hotel room with a flat-screen TV, a dining area with a table and chairs, a kitchenette, and a wardrobe with hanging space.

A modern living room with a sectional sofa, a standing lamp, a large window with sheer curtains, a flat-screen TV, and a built-in air conditioning unit.

10. TownePlace Suites by Marriott Gainesville Northwest

Gainesville

Tanya

฿3,519

฿3,959 total

includes taxes & fees

26 Oct - 27 Oct

A modern breakfast area with labeled dispensers for yogurt, eggs, and milk, a coffee machine, and a chalkboard menu.

An outdoor patio with tables and chairs, a stone wall, and a view of a street with trees and buildings.

A modern reception desk area with a blue geometric wall design, wooden accents, and a visible reception counter.

A Holiday Inn Express building with a modern design, featuring multiple windows and a flat roof.

11. Holiday Inn Express Starke by IHG

Starke

Judy

฿3,461

฿3,842 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.

A modern kitchen with wooden cabinets, a granite countertop, and pendant lighting.

A hotel lobby with a stone wall, a flat-screen TV, orange upholstered seating, and a lamp.

A hotel room with two beds, a large headboard, bedside lamps, and a view of the outdoors through sheer curtains.

12. Drury Inn & Suites Gainesville

Gainesville

Michael

฿3,561

฿4,007 total

includes taxes & fees

2 Nov - 3 Nov

A modern hotel room with a large bed, a desk, a chair, and a TV.

A swimming pool with a wooden deck, lounge chairs, and a red umbrella.

A room with a black leather sofa set, a glass coffee table, and a large black and white mural depicting a street scene.

A workspace with two chairs, a desk, a computer monitor, and a wall-mounted sign reading 'BUSINESS CENTER'.

13. Clarion Pointe Alachua - Gainesville Area

Alachua

Josey

฿2,022

฿2,443 total

includes taxes & fees

22 Nov - 23 Nov

A swimming pool with a metal ladder, surrounded by a white fence and green chairs.

A living room with a curved sofa, a wooden cabinet, and a fish tank.

A hotel room with a patterned carpet, a sofa, a small table, a lamp, and a door with a notice.

A hotel room with a bed, a sofa, a coffee table, and a small table with a lamp.

14. Best Western Waldo Inn and Suites

Waldo

Sarah

฿2,827

฿3,181 total

includes taxes & fees

29 Oct - 30 Oct

A Sleep Inn & Suites building with a sign, surrounded by palm trees and parked cars.

A hotel with a swimming pool, outdoor seating, and a sign for 'Sleep Inn & Suites by Choice Hotels'.

A hotel room with two beds, a desk, a TV, and artwork on the walls.

15. Sleep Inn & Suites University/Shands

Gainesville

Rose

฿2,685

฿3,209 total

includes taxes & fees

11 Nov - 12 Nov

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A hotel room with a sofa, a desk, a chair, a bed, a TV, and a dining table with a glass and cookie.

16. Hotel Indigo Gainesville-Celebration Pointe by IHG

Gainesville

Dalton

฿3,293

฿3,742 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel lobby with a curved ceiling, a central seating area with a sofa and ottoman, a bar area, and a dining space with chairs and tables.

A modern hotel lobby with a breakfast bar, seating area, and a large window.

A hotel reception area with a curved reception desk, a refrigerator stocked with beverages, and a wall with a blue abstract design.

A hotel entrance with a sign reading "Springhill Suites by Marriott" and a modern building in the background.

17. SpringHill Suites by Marriott Gainesville

Gainesville

Hoang

฿2,866

฿3,224 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with wooden cabinets, stainless steel appliances, a microwave, and a coffee maker.

A hotel room with a bed, a TV, a desk, and a sofa.

A hotel room with a sofa, a TV on a wooden stand, a bed with white bedding, a small table, and a painting on the wall.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

18. Staybridge Suites Gainesville I-75 by IHG

Gainesville

Donald

฿4,839

฿5,443 total

includes taxes & fees

25 Oct - 26 Oct

A spacious living area with a curved ceiling, a large flat-screen TV, and a modern sofa.

A modern kitchen with a curved island, pendant lighting, and a map of Gainesville on the wall.

A modern interior with a seating area, large windows, and a stone wall with a menu.

A modern lounge area with seating arrangements, a flat-screen TV, and artwork on the walls.

19. Holiday Inn Gainesville - University Center by IHG

University Heights

Tonya

฿3,327

฿3,742 total

includes taxes & fees

22 Nov - 23 Nov

A modern building with a gray facade, a large window, and a landscaped area with a crocodile sculpture.

A modern dining area with tables and chairs, a kitchen counter, and a sign reading "höm cooking".

A hotel room with two beds, a ceiling fan, a TV, and a desk with a chair.

20. HOM Hotel Gainesville, SureStay Collection by Best Western

Gainesville

Jenna

฿2,434

฿2,738 total

includes taxes & fees

29 Oct - 30 Oct

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Top Santa Fe Hotel Reviews

La Quinta by Wyndham Gainesville

10/10 Excellent

"Great place. Very spacious. Good breakfast."

Red Roof Inn PLUS+ Gainesville

10/10 Excellent

"Surprisingly good facility! Efficient and friendly front desk. Room was very nice. First time traveling with a pet, so received a "pet friendly" room, no carpet and nice area near a wall for our doggy bed. Quiet even though the Interstate was about 100 yards from the window. We often stay with Red Roof, and this was probably the nicest one we have stayed at."

Hotel Indigo Gainesville-Celebration Pointe by IHG

10/10 Excellent

"Great staff interactions."

Drury Inn & Suites Gainesville

10/10 Excellent

"Hotel was immaculate-Staff extremely friendly and Meals included were great"

Hyatt Place Gainesville Downtown

8/10 Good

"Our room has some areas that had not been cleaned properly. There was food debris on the floor around the refrigerator. The only negative about the Hotel is that there is no parking other than a parking garage ($30 a night) a few blocks away or street parking after 8PM. You have to compete with restaurants and businesses for street parking. We needed to leave the hotel at 5am and it was a dark and uncomfortable walk to the garage. A valet would have been nice."

Comfort Suites Gainesville near University

10/10 Excellent

"The amenities Clean Central location Free breakfast and parking!"

Gainesville Lodge

10/10 Excellent

"Upgraded rooms were well appointed and the new coffee shop And bar area was nicely done! We arrived later than intended and Christy was at hand to assist with the key code that had expired ! Great assistance right out of the gate !!"

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

10/10 Excellent

"Clean room, super friendly and helpful staff, and great breakfast. Will stay again when back in the area!"

More cheap stays in Santa Fe

Red Roof Inn PLUS+ Gainesville

3500 Southwest 42nd St Gainesville FL

฿1,905

฿2,143 total

26 Oct - 27 Oct

includes taxes & fees

7.4/10 Good! (1,325 reviews)

Days Inn by Wyndham Gainesville University I-75

920 Nw 69th Ter Gainesville FL

฿2,428

฿2,731 total

25 Oct - 26 Oct

includes taxes & fees

HOM Hotel Gainesville, SureStay Collection by Best Western

3905 Sw 43Rd St Gainesville FL

฿2,434

฿2,738 total

29 Oct - 30 Oct

includes taxes & fees

Sleep Inn & Suites University/Shands

4110 SW 40th Boulevard Gainesville FL

฿2,685

฿3,209 total

11 Nov - 12 Nov

includes taxes & fees

Comfort Inn Gainesville - University Area

3440 SW 40th Blvd Gainesville FL

฿2,709

฿3,236 total

22 Nov - 23 Nov

includes taxes & fees

Comfort Suites Gainesville near University

2603 SW 13TH STREET Gainesville FL

฿2,819

฿3,272 total

22 Nov - 23 Nov

includes taxes & fees

9/10 Wonderful! (1,541 reviews)

Frequently asked questions

What's the best place for a stay in Santa Fe?

Located 18.6 mi (30 km) from the heart of Santa Fe, Drury Inn & Suites Gainesville is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Sleep Inn & Suites University/Shands and Country Inn & Suites by Radisson, Gainesville, FL. See all available top hotels, or vacation rentals in Santa Fe.

If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.

What is staying in Santa Fe like?

Travellers to Santa Fe will find plenty to explore and enjoy. There are 796 hotels and other accommodation options in the surrounding area. Find out more about Santa Fe.

What is there to see in Santa Fe?

Places to visit in the wider area include Turkey Creek Golf Course, O'Leno State Park and San Felasco Hammock Preserve State Park. You'll also find Devil's Milhopper Geological State Park and Gainesville Raceway in the area. Take a look at what more there is to see and do in Expedia's Santa Fe guide.

What's the weather like in Santa Fe?

The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 15°C. The rainiest months in Santa Fe are August, June, July and September, with each month seeing an average of 177 mm of rainfall.

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Find hotels in Santa Fe, FL from ฿2,143

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santa Fe

Check prices for these dates

Filter by

Star rating

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Our top choices for Santa Fe hotels

1. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

2. Hampton Inn & Suites Alachua I-75

3. Best Western Gateway Grand

4. La Quinta by Wyndham Gainesville

5. Fairfield Inn & Suites by Marriott Gainesville I-75

6. Quality Inn Alachua - Gainesville Area

7. Hyatt Place Gainesville Downtown

8. Comfort Suites Gainesville near University

9. Country Inn & Suites by Radisson, Gainesville, FL

10. TownePlace Suites by Marriott Gainesville Northwest

11. Holiday Inn Express Starke by IHG

12. Drury Inn & Suites Gainesville

13. Clarion Pointe Alachua - Gainesville Area

14. Best Western Waldo Inn and Suites

15. Sleep Inn & Suites University/Shands

16. Hotel Indigo Gainesville-Celebration Pointe by IHG

17. SpringHill Suites by Marriott Gainesville

18. Staybridge Suites Gainesville I-75 by IHG

19. Holiday Inn Gainesville - University Center by IHG

20. HOM Hotel Gainesville, SureStay Collection by Best Western

Top Santa Fe Hotel Reviews

La Quinta by Wyndham Gainesville

Red Roof Inn PLUS+ Gainesville

Hotel Indigo Gainesville-Celebration Pointe by IHG

Drury Inn & Suites Gainesville

Hyatt Place Gainesville Downtown

Comfort Suites Gainesville near University

Gainesville Lodge

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

More cheap stays in Santa Fe

Red Roof Inn PLUS+ Gainesville

Days Inn by Wyndham Gainesville University I-75

HOM Hotel Gainesville, SureStay Collection by Best Western

Sleep Inn & Suites University/Shands

Comfort Inn Gainesville - University Area

Comfort Suites Gainesville near University

Frequently asked questions

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