The Best Hotels Closest to Santa Fe Depot Museum in Gainesville - 2026 Updated Prices

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Our top choices for Santa Fe Depot Museum hotels

A modern hotel lobby with a wooden ceiling, a large TV, a sofa, a coffee table, and a patterned floor.

A modern hotel lobby with a wooden ceiling, a reception desk, a seating area with green sofas, and a visible kitchen in the background.

A swimming pool with clear lane markings, adjacent lounge chairs, and a tiled floor.

A spacious indoor area with a curved ceiling, a central bar area, multiple seating arrangements, and a large table in the foreground.

1. Fairfield Inn & Suites by Marriott Gainesville I-35

1.8 km from Santa Fe Depot Museum

Lori

฿3,176

฿3,652 total

includes taxes & fees

7 Sept - 8 Sept

A buffet with labeled containers of omelets and other dishes.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A hotel room with a bed, a desk, a chair, a sofa, and a ceiling fan.

A Holiday Inn Express & Suites building with a covered entrance and a large tree in front.

2. Holiday Inn Express Hotel & Suites Gainesville by IHG

1.1 km from Santa Fe Depot Museum

Julissa

฿3,179

฿3,655 total

includes taxes & fees

10 Sept - 11 Sept

A modern hotel room with a large bed, a desk, a chair, and a sofa.

A gym with treadmills, elliptical machines, and weight machines.

A reception area with a Days Inn sign, a counter with a tiled backsplash, a television, and a coffee machine.

A motel with a covered parking area and multiple cars parked.

3. Days Inn by Wyndham Gainesville

2.5 km from Santa Fe Depot Museum

Sonya

฿2,781

฿3,199 total

includes taxes & fees

31 Aug - 1 Sept

A spacious living area with a sofa, a glass-top coffee table, a desk with a computer, and a magazine rack. There is a dining area with tables and chairs in the background.

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

A vending machine with various drinks and snacks, a push door, and a digital display.

A hotel hallway with carpeted floors, doors on both sides, and a ceiling with recessed lighting.

4. Super 8 by Wyndham Gainesville TX

2.7 km from Santa Fe Depot Museum

Irene

฿2,285

฿2,627 total

includes taxes & fees

31 Aug - 1 Sept

A large indoor swimming pool with clear views through tall windows, a lounge chair, and a table with chairs.

A hotel room with a large bed, wooden headboard, bedside tables, a desk with a chair, and a television.

A reception desk with a sign reading "Comfort Suites." There are two digital kiosks and a reception counter.

A hotel kitchen with a central island, wooden cabinets, and a breakfast bar.

5. Comfort Suites Gainesville

2.5 km from Santa Fe Depot Museum

Jennifer

฿2,354

฿2,707 total

includes taxes & fees

8 Sept - 9 Sept

A kitchen with a countertop, a refrigerator, a ceiling fan, and a window.

A motel with a brick facade, a covered parking area, and a car parked in front.

A hotel room with a desk, a television on a stand, a mirror, and a small cabinet.

A small office with a desk, computer, chair, and a clock on the wall.

6. Budget Host Motel Gainesville

2.7 km from Santa Fe Depot Museum

Mark

฿2,318

฿2,665 total

includes taxes & fees

31 Aug - 1 Sept

A hotel room with two beds, a desk with a chair, a television, and a minibar.

Two refrigerated beverage dispensers labeled 'CHILLED' and 'FROZEN' with various drinks inside.

A modern lobby with a green leather sofa, a glass coffee table, and potted plants.

A breakfast bar with coffee machines, a refrigerator, and a seating area with a wooden table and chairs.

7. Quality Inn Gainesville

0.9 km from Santa Fe Depot Museum

Esmeralda

฿1,730

฿2,014 total

includes taxes & fees

11 Sept - 12 Sept

A spacious living area with a stone accent wall, a brown sofa, and a kitchen in the background.

A hotel room with two beds, a desk with a TV, a mirror, and a lamp.

A long corridor with a dining area featuring tables and chairs, a kitchen area, and a reception desk.

A gazebo with a roof and open sides, surrounded by grass and trees.

8. Loyalty Inn Gainesville

3 km from Santa Fe Depot Museum

Sonija

฿1,639

฿1,885 total

includes taxes & fees

31 Aug - 1 Sept

A hotel room with a bed, a desk with a computer, a TV, a microwave, and a refrigerator.

A modern lobby with a green sofa, blue armchairs, a glass coffee table, and potted plants.

9. Suburban Studios Gainesville

0.9 km from Santa Fe Depot Museum

Michele

฿1,639

฿1,885 total

includes taxes & fees

31 Aug - 1 Sept

A spacious kitchen with checkered flooring, wooden cabinets, and various appliances.

A laundry area with a wall-mounted soap, bleach, and softener dispenser, a washing machine, and stacked dryers.

A modern hotel room with a large bed, a desk, and a view of the cityscape.

A gym with treadmills, elliptical machines, and a weight bench.

10. Hampton Inn & Suites Gainesville

6.4 km from Santa Fe Depot Museum

Joanna

฿2,812

฿3,247 total

includes taxes & fees

8 Sept - 9 Sept

A spacious living room with patterned sofas, a coffee table, and a flat-screen TV mounted on the wall.

A reception area with a curved reception desk, a flat-screen TV mounted on the wall, and framed artwork above the desk.

A hotel room with two beds, a desk, a TV, and a window.

A Best Western hotel with a brick facade, a covered entrance, and stone pillars.

11. Best Western Red River Inn & Suites

13.9 km from Santa Fe Depot Museum

Juan

฿3,178

฿3,560 total

includes taxes & fees

15 Sept - 16 Sept

A hotel room with two beds, each with a green headboard, white bedding, and red accents. There are abstract paintings on the wall above the beds.

A small, modern room with a gray sofa, a green armchair, a bed with a red blanket, a white pillow, and a painting on the wall.

A bathroom with a toilet, a shower curtain, a towel rack with towels, and a toilet paper holder.

A compact kitchen area with a microwave and a black dishwasher.

12. Lindsay Inn

7.9 km from Santa Fe Depot Museum

Terri

฿2,318

฿2,596 total

includes taxes & fees

2 Sept - 3 Sept

A spacious lobby with a reception desk, a staircase, and seating area.

A swimming pool with a metal railing, surrounded by lounge chairs and a door in the background.

A hotel with a red roof, a covered entrance, and a sign for La Quinta Inn & Suites.

A spacious lobby with a fireplace, patterned wallpaper, and modern seating arrangements.

13. La Quinta Inn & Suites by Wyndham Gainesville

6.8 km from Santa Fe Depot Museum

Teresa

฿3,068

฿3,598 total

includes taxes & fees

1 Sept - 2 Sept

A hotel room with a bed, bedside table, lamp, and a television on a dresser.

A building with a covered entrance, a clock, and a sign with a flag.

A spacious lobby with a ceiling fan, a reception desk, a refrigerator, and a door leading to the outside.

A kitchen with wooden cabinets, a black countertop, and a black rug.

14. OYO Hotel Valley View TX, I-35

16.5 km from Santa Fe Depot Museum

Raymond

฿2,135

฿2,520 total

includes taxes & fees

13 Sept - 14 Sept

A modern living room with a fireplace, two bean bag chairs, a television, and large windows with blinds.

A modern hotel lobby with dark wood flooring, comfortable seating, a flat-screen TV, and a reception desk.

A living room with a sofa, two bean bags, a coffee table, and a TV mounted on the wall.

A hotel room with a bed, a chair, a small table, and a bathroom with a sink and mirror.

15. Red River Inn And Suites

13.9 km from Santa Fe Depot Museum

Ronn

฿3,444

฿3,857 total

includes taxes & fees

10 Sept - 11 Sept

A rustic interior with wooden floors, hanging plants, and a rustic ceiling.

A rustic dining area with a stone fireplace, wooden ceiling, and a table set for dining.

A wooden cabin with a porch, surrounded by trees and a garden with yellow flowers.

An outdoor seating area with wooden chairs and tables, surrounded by trees and string lights.

16. Oak Meadow Ranch

15 km from Santa Fe Depot Museum

Isaac

฿5,066

฿7,458 total

includes taxes & fees

31 Aug - 1 Sept

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Compare popular hotels close to Santa Fe Depot Museum

Property	Property class	Guest rating
Fairfield Inn & Suites by Marriott Gainesville I-35	8.6 Excellent 1,003 reviews	View
Holiday Inn Express Hotel & Suites Gainesville by IHG	7.8 Good 1,000 reviews	View
Days Inn by Wyndham Gainesville	7.8 Good 1,003 reviews	View
Super 8 by Wyndham Gainesville TX	7.4 Good 1,001 reviews	View
Comfort Suites Gainesville	6.8 1,006 reviews	View

Top Santa Fe Depot Museum Hotel Reviews

Comfort Suites Gainesville

10/10 Excellent

"Clean room and super close to winstar!"

Budget Host Motel Gainesville

8/10 Good

"It was clean, and easy to rent a room for the night. It was also relatively quiet in the room as close to the highway as it was. Compared the cost of other hotels within half a mile it’s definitely economical if you just need a place to rest for the night."

Hampton Inn & Suites Gainesville

10/10 Excellent

"Great Stay"

Lindsay Inn

8/10 Good

"I must admit, when we drove up I was like "what did I sign up for"? We were debating in the car if we even wanted to get out. We walk into the office and was immediately met with a smell. Not to be mean, but we immediately knew the nationality of the people running the office; if you know, you know. I was booked for two nights, but at this point, I was almost willing to take my loss and just leave. Let me tell you, I'm so glad we decided to just go look at the room. We opened the door and it had such a pleasant smell. The room was clean. It definitely took me by surprise. Where we were pleased with the room, of course it had its bad points. For one, once I pulled the covers back to spray it with lysol, we noticed the bedspread was stained with who knows what. The towels were dingy and there was some type of patch covering up something in the bathtub. We didn't complain to the office about any of it. Other than that, it was a doable stay. For the price I would say it was good. My main thing was the fact that it was clean and smelled pleasant."

Red River Inn And Suites

10/10 Excellent

"I had a great stay. Everything was good..."

Best Western Red River Inn & Suites

10/10 Excellent

"Staff was absolutely amazing and friendly. Close to WinStar. Highly recommend"

La Quinta Inn & Suites by Wyndham Gainesville

8/10 Good

"Really clean, comfortable, and spacious roomfor a low price (weeknight). I really didn't think of the La Quinta brand as being a nice hotel, but I would highly recommend this one."

Super 8 by Wyndham Gainesville TX

10/10 Excellent

"Very Friendly People and would definitely recommend to My Friends!"

Quality Inn Gainesville

8/10 Good

"TV remotes not working"

Other attractions near Santa Fe Depot Museum

Cooke County Courthouse

7.6/10 (89 reviews)

After visiting Cooke County Courthouse, make a plan to see the other sights and activities in Gainesville. While you're in the area, find time to visit its casinos.

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Depot Park

Depot Park is just one of the places to see in Gainesville, so why not enjoy the other things to explore during your travels? While in this family-friendly area, find time to visit its casinos.

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Butterfield Stage Players

7.2/10 (64 reviews)

You can enjoy a show at Butterfield Stage Players during your stay in Gainesville. While you're in the area, find time to visit its casinos.

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State Theater

7.4/10 (54 reviews)

You can enjoy a show at State Theater during your stay in Gainesville. While you're in the area, find time to visit its casinos.

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Morton Museum

7.2/10 (68 reviews)

You can spend time studying the exhibits at Morton Museum during your trip to Gainesville. While you're in the area, find time to visit its casinos.

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Tom Thumb Park

After visiting Tom Thumb Park, make a plan to see the other sights and activities in Gainesville. While in this family-friendly area, find time to visit its casinos.

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Jaycee Park

After visiting Jaycee Park, make a plan to see the other sights and activities in Gainesville. While in this family-friendly area, find time to visit its casinos.

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Gainesville War Memorial

8.0/10 (109 reviews)

Find out about the history of Gainesville with a stop at Gainesville War Memorial. While you're in the area, find time to visit its casinos.

See properties

Frequently asked questions

What's the area like around Santa Fe Depot Museum?

Santa Fe Depot Museum is located in a welcoming area of Gainesville known for its first-class casinos. If you're looking for a convenient place to stay, take a look at the 16 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Santa Fe Depot Museum?

Quality Inn Gainesville is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. It's located just a short 0.5 mi (0.9 km) from Santa Fe Depot Museum. Other good options within a short distance include Holiday Inn Express Hotel & Suites Gainesville by IHG and Suburban Studios Gainesville.

How many hotels are there near Santa Fe Depot Museum?

Expedia has 16 hotels and other accommodation options within a mile from Santa Fe Depot Museum.

If I need to cancel the hotel reservation for my stay near Santa Fe Depot Museum, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals near Santa Fe Depot Museum.

What can I see and do near Santa Fe Depot Museum?

You can enjoy live performances at Butterfield Stage Players and State Theater. Get outside and spend some time strolling around Leonard Park, Tom Thumb Park and Jaycee Park. Gainesville War Memorial and Frank Buck Zoo are both worth a visit while you're out exploring.

Search Hotels Near Santa Fe Depot Museum, Gainesville

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Our top choices for Santa Fe Depot Museum hotels

1. Fairfield Inn & Suites by Marriott Gainesville I-35

2. Holiday Inn Express Hotel & Suites Gainesville by IHG

3. Days Inn by Wyndham Gainesville

4. Super 8 by Wyndham Gainesville TX

5. Comfort Suites Gainesville

6. Budget Host Motel Gainesville

7. Quality Inn Gainesville

8. Loyalty Inn Gainesville

9. Suburban Studios Gainesville

10. Hampton Inn & Suites Gainesville

11. Best Western Red River Inn & Suites

12. Lindsay Inn

13. La Quinta Inn & Suites by Wyndham Gainesville

14. OYO Hotel Valley View TX, I-35

15. Red River Inn And Suites

16. Oak Meadow Ranch

Compare popular hotels close to Santa Fe Depot Museum

Top Santa Fe Depot Museum Hotel Reviews

Comfort Suites Gainesville

Budget Host Motel Gainesville

Hampton Inn & Suites Gainesville

Lindsay Inn

Red River Inn And Suites

Best Western Red River Inn & Suites

La Quinta Inn & Suites by Wyndham Gainesville

Super 8 by Wyndham Gainesville TX

Quality Inn Gainesville

Other attractions near Santa Fe Depot Museum

Cooke County Courthouse

Depot Park

Butterfield Stage Players

State Theater

Morton Museum

Tom Thumb Park

Jaycee Park

Gainesville War Memorial

Frequently asked questions