Santa Clara Travel Guide
Panama City
Visit Santa Clara
Things to do
Panama City: Poin Glass Observation Deck Ticket with VR Tour
฿1,053
per adult
100% of travellers recommend
Transfer to Panama Canal (Miraflores Locks)
฿459
per adult
100% of travellers recommend
Panama City: POIN Swing Experience
฿1,053
per adult
100% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
฿1,509
per adult
96% of travellers recommend
Panama City: Poin Full Package Experience
฿5,084
per adult
98% of travellers recommend
Monkey and Sloth Jungle Habitat Panama Tour
฿1,378
per adult
96% of travellers recommend
Top hotels in Santa Clara
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
The price is ฿4,549 per night from 27 Sept to 28 Sept
฿4,549
฿5,004 total
27 Sept - 28 Sept
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,951 reviews)
"All good"
Reviewed on 14 Sept 2026
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
The price is ฿4,197 per night from 27 Sept to 28 Sept
฿4,197
฿4,835 total
27 Sept - 28 Sept
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,716 reviews)
"10/10"
Reviewed on 14 Sept 2026
Central Hotel Panama Casco Viejo
Plaza de la Independencia Casco Viejo Panama City Panama
The price is ฿6,061 per night from 13 Oct to 14 Oct
฿6,061
฿6,668 total
13 Oct - 14 Oct
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and 3 restaurants. Our guests praise the helpful staff and the clean rooms in their ...
9/10 Wonderful! (1,020 reviews)
"The room was small with an inside view."
Reviewed on 13 Sept 2026
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is ฿5,248 per night from 20 Sept to 21 Sept
฿5,248
฿5,773 total
20 Sept - 21 Sept
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.6/10 Excellent! (1,724 reviews)
"Great place"
Reviewed on 14 Sept 2026
Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
The price is ฿9,198 per night from 1 Oct to 2 Oct
฿9,198
฿9,198 total
1 Oct - 2 Oct
includes taxes & fees
Stay at this beach resort in Veracruz. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the pool and the helpful staff in their reviews. ...
7.8/10 Good! (1,078 reviews)
"Location and food options were decent. Amenities, such as the pools and outside activities were nice, but there are some maintenance things that need to be done, such as the pool table being stained and ripped. Coast was nice, but we couldn’t ever going into the water due to health hazards; purple ..."
Reviewed on 13 Sept 2026
Ramada Plaza by Wyndham Panama Punta Pacifica
Via Israel y Calle 71, San Francisco Panama City Panama
Fully refundableReserve now, pay when you stay
The price is ฿3,072 per night from 3 Oct to 4 Oct
฿3,072
฿3,380 total
3 Oct - 4 Oct
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Clara
Find the best Santa Clara areas for the activities you enjoy most. Learn more about Santa Clara
Learn more about Santa Clara
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by Freddy Dominguez
Open Photo by Freddy Dominguez
Bella Vista
Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.
El Cangrejo
The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Lotería Station or Santo Tomás Station to explore sights like Via Espana.
