Santa Ana Travel Guide

Antigua Guatemala


Popular places to visit

Things to do


Top hotels in Santa Ana

Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is ฿2,093 per night from 1 Feb to 2 Feb
฿2,093
per night
1 Feb - 2 Feb
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (3,116 reviews)
Nice room nice pool nice gym. Premier suite was worthwhile

Reviewed on 25 Dec 2025

Barceló Guatemala City
Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center

4.5 out of 5
Calzada Roosevelt 22-43 Guatemala City Guatemala
The price is ฿3,379 per night from 4 Jan to 5 Jan
฿3,379
per night
4 Jan - 5 Jan
Stay at this spa hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
9/10 Wonderful! (1,010 reviews)
Yes

Reviewed on 28 Dec 2025

Tikal Futura Hotel & Convention Center
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
The price is ฿3,303 per night from 11 Jan to 12 Jan
฿3,303
per night
11 Jan - 12 Jan
Stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,632 reviews)
Room fan wasn't working but staff was quick to change our room & upgrade us! Clean and great breakfast. Staff is very friendly. Hot tub is a nice touch to watch the sunset.

Reviewed on 28 Dec 2025

Wyndham Garden Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is ฿7,502 per night from 6 Jan to 7 Jan
฿7,502
per night
6 Jan - 7 Jan
Stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa and 2 restaurants. Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,019 reviews)
Clean room, incredible staff , spa , gardens , food. Amazing Hotel

Reviewed on 29 Dec 2025

Hotel Museo Spa Casa Santo Domingo
Porta Hotel Antigua

Porta Hotel Antigua

4.5 out of 5
8va Calle Poniente No1 Antigua Guatemala Sacatepequez
The price is ฿5,571 per night from 6 Jan to 7 Jan
฿5,571
per night
6 Jan - 7 Jan
Stay at this luxury hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,003 reviews)
Great service

Reviewed on 15 Dec 2025

Porta Hotel Antigua
Adriatika Hotel & Residence

Adriatika Hotel & Residence

4.5 out of 5
4 av 20-44 Zona 14 Guatemala City Guatemala
The price is ฿3,624 per night from 2 Feb to 3 Feb
฿3,624
per night
2 Feb - 3 Feb
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (959 reviews)
It was a very nice stay everything was great

Reviewed on 28 Dec 2025

Adriatika Hotel & Residence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

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Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Barrio de La Concepción
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Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Historic Center


Santa Ana Travel Guide