Santa Ana Travel Guide

Panama City

Photo by Isa
Photo by Isa

Popular places to visit

Multiplaza Pacific Mall

Multiplaza Pacific Mall

During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Avenida Balboa

Avenida Balboa

You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
Fuerte Amador Resort & Marina

Fuerte Amador Resort & Marina

Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Visit the shops and top-notch restaurants in this vibrant area.

Fuerte Amador Resort & Marina
Panama

Miraflores Locks

Learn about the local history of Ancon when you spend time at Miraflores Locks. Visit the casinos and shops in this vibrant area.

Miraflores Locks
Calle 50

Calle 50

You can find out about the history of Panama City when you stop by Calle 50. Discover the area's shops or seek out its local tours.

Calle 50

Things to do

Slingshot Tour Panama

Slingshot Tour Panama

฿3,778
per adult
76% of travellers recommend
Slingshot Tour Panama
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

฿4,880
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

฿1,051
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
Panama City Visit an Indian town Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

฿1,638
per adult
96% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
Panama City Tour and Panama Canal – Miraflores Locks Experience

Panama City Tour and Panama Canal – Miraflores Locks Experience

฿1,146
per adult
96% of travellers recommend
Panama City Tour and Panama Canal – Miraflores Locks Experience
The Panama Barcrawl - The OG Crawl

The Panama Barcrawl - The OG Crawl

฿2,129
per adult
96% of travellers recommend
The Panama Barcrawl - The OG Crawl
See all activities in Panama City

Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3 out of 5
C. 16 Oeste, Panama City, Provincia de Panamá
The price is ฿2,321 per night from 14 Sept to 15 Sept
฿2,321
฿2,554 total
14 Sept - 15 Sept
includes taxes & fees
Stay at this 3-star condo in Panama City. Enjoy free Wi-Fi, a 24-hour front desk and a garden. Popular attractions Albrook Shopping Mall and Cinta Costera are ...
9.2/10 Wonderful! (44 reviews)
"Very helpful and offered great suggestions. Cant wait to return!"

Reviewed on 12 Jul 2025

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is ฿3,716 per night from 25 Aug to 26 Aug
฿3,716
฿4,088 total
25 Aug - 26 Aug
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (4,153 reviews)
"No tenían abierta la alberca"

Reviewed on 14 Aug 2025

Hotel Riu Plaza Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
The price is ฿2,617 per night from 20 Aug to 21 Aug
฿2,617
฿2,879 total
20 Aug - 21 Aug
includes taxes & fees
Stay at this 4-star spa B&B in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located ...
9/10 Wonderful! (405 reviews)
"The check-in process was quick and easy although there was only one person working and there were several persons waiting to check-in. The room and lobby area were clean. The breakfast had several options which was great. I stayed there during the week previously abd the brekafast was the normal ..."

Reviewed on 11 Aug 2025

Waymore Hotel Spa & Casino
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111, Panama City, Panama
The price is ฿2,478 per night from 18 Aug to 19 Aug
฿2,478
฿2,726 total
18 Aug - 19 Aug
includes taxes & fees
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. ...
7.6/10 Good! (1,002 reviews)
"The hotel was very nice but we never did have hot water in the bathroom the whole time we were there."

Reviewed on 8 Aug 2025

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is ฿3,702 per night from 8 Sept to 9 Sept
฿3,702
฿4,072 total
8 Sept - 9 Sept
includes taxes & fees
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (2,185 reviews)
Quick Stay
"It was just a quick overnight. Having the shuttle to the airport is a real plus."

Reviewed on 12 Aug 2025

Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
The price is ฿6,404 per night from 4 Sept to 5 Sept
฿6,404
฿6,404 total
4 Sept - 5 Sept
includes taxes & fees
Stay at this 4-star beach resort in Veracruz. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the pool and the helpful staff in their reviews. ...
7.2/10 Good! (1,009 reviews)
Grandbaby’s 1st Family Vacay
"Loved to Italian n French food. Bed were very comfortable but pillows were too thick and uncomfortable. Didn’t get the Internet information to connect to. I got a taxi at the airport for my whole family cause it was cheaper than the resorts transportation."

Reviewed on 14 Aug 2025

Dreams Playa Bonita Panama - All Inclusive
See all 1,499 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

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Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Casco Viejo
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San Felipe

While visiting San Felipe, you might make a stop by sights like Metropolitan Cathedral of Panama and Interoceanic Canal Museum.

San Felipe
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El Chorrillo

While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Metropolitan Cathedral of Panama are some notable places to visit nearby.

El Chorrillo
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Curundu

While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.

Curundu
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Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Calidonia
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Balboa

The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Bridge of the Americas are a few top places to visit.

Balboa

Santa Ana Travel Guide