Santa Ana Travel Guide

Panama City

Plaza Santa Ana, Panama Casco Viejo
Santa Ana

Popular places to visit

Things to do


Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
The price is ฿3,186 per night from 12 Apr to 13 Apr
฿3,186
฿4,466 total
12 Apr - 13 Apr
includes taxes & fees
Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
9/10 Wonderful! (87 reviews)
Nice place, easy walk from Casco Viejo. The pool area was great, but room wasn’t the cleanest. We had to request bedding for the second bed but weren’t given a blanket.

Reviewed on 7 Apr 2026

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is ฿4,146 per night from 5 May to 6 May
฿4,146
฿4,560 total
5 May - 6 May
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,267 reviews)
Very friendly and helpful staff. Floors a bit musty - We got a room on the 24th floor and asked for a change because it was very musty and a bit suffocating. Without any issue we we got another room on the 18th floor which was better. This may be has to do with airflow and the carpet as when in the ...

Reviewed on 10 Apr 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is ฿4,069 per night from 4 May to 5 May
฿4,069
฿4,688 total
4 May - 5 May
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,504 reviews)
Shuttle was small and we had to wait an hour

Reviewed on 9 Apr 2026

Crowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is ฿4,058 per night from 1 May to 2 May
฿4,058
฿4,464 total
1 May - 2 May
includes taxes & fees
Stay at this spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,004 reviews)
The staff greeted us with a warm smile every day. The breakfast was delicious. We would definitely stay here again.

Reviewed on 10 Apr 2026

Sheraton Grand Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
The price is ฿3,653 per night from 12 Apr to 13 Apr
฿3,653
฿4,018 total
12 Apr - 13 Apr
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
7.8/10 Good! (1,008 reviews)
Very nice Hotel. The staff are exceptionally friendly and really care. They were very good to us.

Reviewed on 9 Apr 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
The price is ฿1,817 per night from 12 Apr to 13 Apr
฿1,817
฿1,998 total
12 Apr - 13 Apr
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and room service. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (1,790 reviews)
Excelente

Reviewed on 8 Apr 2026

Principe Hotel and Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

View of the Panama City Old Town

Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Casco Viejo
Balcony of a colonial house, Casco Viejo, Panama City, Panama, Central America

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

San Felipe
Default Image

El Chorrillo

While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Flag of Cerro Ancón are some notable places to visit nearby.

El Chorrillo
Calidonia

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.

Calidonia
Balboa

Balboa

The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Flag of Cerro Ancón are a few top places to visit.

Balboa
Default Image

Curundu

While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.

Curundu


Santa Ana Travel Guide