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Our top choices for Sanctuary hotels

Lovers Key Resort

Lovers Key Resort
3.0 star property
30.3 km from Sanctuary
8.8 out of 10, Excellent, (1,024 reviews)
"Wonderful place to relax and a good spot for exploring the coastal area. "
United States
Gerald L.
Lovers Key Resort

Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
30.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,002 reviews)
"Clean and tidy hotel, friendly staff and the breakfast is excellent. 4th time we have stayed here in last 15 months"
United Kingdom
Adam
The price is ฿6,026
฿6,719 total
includes taxes & fees
27 Jan - 28 Jan
Homewood Suites by Hilton - Fort Myers

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
30.8 km from Sanctuary
8.8 out of 10, Excellent, (1,005 reviews)
"Great stay "
United States
Brandon
The price is ฿5,045
฿5,625 total
includes taxes & fees
26 Jan - 27 Jan
Doubletree by Hilton Fort Myers at Bell Tower Shops

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.6 out of 10, Excellent, (806 reviews)
"Good location "
United States
Lynn
The price is ฿4,032
฿4,495 total
includes taxes & fees
25 Jan - 26 Jan
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Redfish Retreat - South End Pool Home

Redfish Retreat - South End Pool Home
2.0 star property
29 km from Sanctuary
The price is ฿8,166
฿25,906 total
includes taxes & fees
26 Jan - 27 Jan
Redfish Retreat - South End Pool Home

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
29.5 km from Sanctuary
8.8 out of 10, Excellent, (1,002 reviews)
"Great stay"
United States
Erica
The price is ฿5,476
฿6,105 total
includes taxes & fees
27 Jan - 28 Jan
Hilton Garden Inn Ft Myers

GullWing Beach Resort

GullWing Beach Resort
3.5 star property
27.3 km from Sanctuary
9.4 out of 10, Exceptional, (932 reviews)
"The view of the beach was spectacular. "
United States
Carol
The price is ฿7,313
฿19,350 total
includes taxes & fees
29 Jan - 30 Jan
GullWing Beach Resort

Flamingo Inn

Flamingo Inn
3.0 star property
26.9 km from Sanctuary
7.8 out of 10, Good, (986 reviews)
"Quiet, clean and updated room. Easy walk to the beach."
United States
KATHLEEN
The price is ฿3,996
฿6,628 total
includes taxes & fees
25 Jan - 26 Jan
Flamingo Inn

Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
25.4 km from Sanctuary
7.4 out of 10, Good, (1,004 reviews)
"Great place to stay."
United States
David
The price is ฿3,500
฿3,903 total
includes taxes & fees
25 Jan - 26 Jan
Candlewood Suites Fort Myers Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
23.1 km from Sanctuary
9.4 out of 10, Exceptional, (1,006 reviews)
"Good conditions..excellent staff "
United States
Edelsi
The price is ฿4,719
฿5,262 total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
22.9 km from Sanctuary
8.4 out of 10, Very good, (1,005 reviews)
"Clean room great breakfast staff very friendly and courteous. "
United States
Paula
The price is ฿4,681
฿5,220 total
includes taxes & fees
27 Jan - 28 Jan
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

TriLuxe Inn & Studios

TriLuxe Inn & Studios
2.0 star property
22.7 km from Sanctuary
8.2 out of 10, Very good, (17 reviews)
"Everything was great, will definitely be coming back"
United States
Ruben
The price is ฿2,782
฿4,112 total
includes taxes & fees
21 Jan - 22 Jan
TriLuxe Inn & Studios

Summerwind Studios

Summerwind Studios
2.0 star property
22.6 km from Sanctuary
8.0 out of 10, Very good, (11 reviews)
"Very clean and roomy. Quiet neighborhood. Loves the shower; so relaxing. Only complaint is that we could have used some drinking glasses. I would stay here again. "
United States
Micki
The price is ฿2,719
฿4,042 total
includes taxes & fees
21 Jan - 22 Jan
Summerwind Studios

Lazy Cuckoo Inn

Lazy Cuckoo Inn
2.0 star property
22.1 km from Sanctuary
9.0 out of 10, Wonderful, (234 reviews)
"Very nice. Great for a short or longer term stay."
United States
Finley
The price is ฿2,500
฿3,798 total
includes taxes & fees
25 Jan - 26 Jan
Lazy Cuckoo Inn

Riverfront Home w Private Dock Pool Beaches

Riverfront Home w Private Dock Pool Beaches
2.0 star property
26 km from Sanctuary
The price is ฿15,137
฿32,370 total
includes taxes & fees
1 Feb - 2 Feb
Riverfront Home w Private Dock Pool Beaches

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
22 km from Sanctuary
8.6 out of 10, Excellent, (923 reviews)
"Staff was very helpful at check-in; room was clean. As a solo female traveler, I felt safe. "
United States
Kimberly
Latitude 26 Waterfront Resort & Marina

Pointe Estero Beach Resort

Pointe Estero Beach Resort
2.0 star property
27.3 km from Sanctuary
9.2 out of 10, Wonderful, (1,001 reviews)
"Nice place Clean rooms Friendly staff "
United States
SALMAN
The price is ฿9,188
฿20,395 total
includes taxes & fees
21 Jan - 22 Jan
Pointe Estero Beach Resort

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
21.8 km from Sanctuary
9.0 out of 10, Wonderful, (1,139 reviews)
"The breakfast was good "
United States
Ileana
The price is ฿5,917
฿7,299 total
includes taxes & fees
22 Jan - 23 Jan
Lani Kai Beachfront Resort

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
25.2 km from Sanctuary
5.8 out of 10, (1,003 reviews)
"Beautiful place "
United States
Blaine
The price is ฿2,540
฿3,051 total
includes taxes & fees
23 Jan - 24 Jan
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
23.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,173 reviews)
"Is great place to stay."
United States
Anastassia
The price is ฿4,469
฿4,983 total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanctuary

Find the best Sanctuary areas for the activities you enjoy most.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Shell Harbor

While Shell Harbor isn't home to many top sights, Sanibel Moorings Botanical Gardens and Sanibel Sea School are some notable places to visit nearby.

Top Sanctuary Hotel Reviews

Frequently asked questions

What is Sanctuary like?
Travellers are sure to enjoy a stay in Sanibel's Sanctuary neighbourhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels will I be able to find in the Sanctuary area?
With 11 Expedia hotels and other accommodation options in Sanctuary to choose from, this is a good starting point for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals available in Sanctuary.
What is there to do around this Sanibel neighbourhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.

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