What's it like in Uptown Central?

Guests are sure to enjoy their time checking out all that San Antonio's Uptown Central neighbourhood has to offer. Are you looking for Uptown Central travel tips? Make sure that you visit Marion Koogler McNay Art Museum and Alamo Quarry Market while you're in the neighbourhood.

What's the best accommodation in Uptown Central?

Based on our traveller data, Heritage Inn & Suites San Antonio Airport, Trademark Wyndham is one of the top choices for your stay in Uptown Central. This hotel is a short 14-minute walk from North Star Mall, and it offers free breakfast and an outdoor pool. Other good options for your stay in the area include Wyndham Garden San Antonio Airport and La Quinta Inn & Suites by Wyndham San Antonio Airport .

How many hotels will I be able to find in the Uptown Central area?

Expedia has 392 hotels and other accommodation options in Uptown Central to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Uptown Central, will I receive a refund?

Yes, the majority of room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to view the top deals on offer in Uptown Central.

What can I see and do in this San Antonio neighbourhood?

Uptown Central's sights and attractions like Toilet Seat Museum, Marion Koogler McNay Art Museum and Parchman Stremmel Galleries offer insight into the local culture. You could also plan a visit to Alamo Quarry Market or San Antonio Zoo and Aquarium while you're in the neighbourhood. A few places to visit in the area around Uptown Central include Harry B Orem Stadium, Quarry Golf Club and Regal Alamo Quarry. McDermott Center and Gayle and Tom Benson Stadium are also worth a visit when you're out sightseeing in San Antonio.

The Best Hotels in Uptown Central, San Antonio - 2026 Updated Prices

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Our top choices for Uptown Central hotels

A buffet with various food items, including omelets and other dishes, served in metal containers.

1. Holiday Inn Express San Antonio-Airport by IHG

Uptown Central

Lori

฿4,139 total

includes taxes & fees

23 Nov - 24 Nov

A modern lobby with a sofa, patterned chairs, a central ottoman, and a chandelier.

2. Drury Plaza Hotel San Antonio Airport

Uptown Central

Darlene

฿4,561 total

includes taxes & fees

27 Oct - 28 Oct

A modern bar area with seating and a staircase leading to an upper level.

3. Embassy Suites by Hilton San Antonio Airport

Uptown Central

Trenton

฿5,053 total

includes taxes & fees

1 Nov - 2 Nov

A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

4. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Uptown Central

Roberta

฿3,163 total

includes taxes & fees

1 Nov - 2 Nov

A building with a large arched doorway, a balcony with a railing, and a tree with green foliage in the foreground.

5. Estancia del Norte San Antonio, Tapestry Collection by Hilton

Uptown Central

Lauro

฿4,626 total

includes taxes & fees

5 Nov - 6 Nov

A spacious living area with a dark blue sofa, four grey armchairs, and three metallic coffee tables.

6. La Quinta Inn & Suites by Wyndham San Antonio Airport

Uptown Central

Vanesa

฿3,169 total

includes taxes & fees

27 Oct - 28 Oct

A multi-story hotel with a stone facade, multiple windows, and a sign indicating it is a Homewood Suites Hilton.

7. Homewood Suites by Hilton San Antonio Airport

Uptown Central

Azeneth

฿4,122 total

includes taxes & fees

14 Nov - 15 Nov

A modern living room with a sofa, coffee table, and a large abstract painting.

8. Marriott San Antonio Airport

Uptown Central

Erika

฿4,818 total

includes taxes & fees

22 Nov - 23 Nov

A modern kitchen with a central island, built-in appliances, and a coffee station.

9. Wyndham Garden San Antonio Airport

Uptown Central

Johnny

฿3,367 total

includes taxes & fees

1 Nov - 2 Nov

A modern interior with a curved ceiling, a sectional sofa, a round coffee table, and a dining area with chairs and a table.

10. SpringHill Suites by Marriott San Antonio Airport

Uptown Central

jennifer

฿3,584 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio with metal chairs, a barbecue grill, and string lights.

11. Home2 Suites by Hilton San Antonio Airport, TX

Uptown Central

Darlene

฿4,251 total

includes taxes & fees

15 Nov - 16 Nov

A spacious hotel lobby with a long marble reception desk, multiple seating areas, and a large television screen.

12. Hampton Inn & Suites San Antonio-Airport

Uptown Central

Omar

฿3,335 total

includes taxes & fees

15 Nov - 16 Nov

A hotel lobby with a reception desk, seating area with sofas and chairs, and a patterned carpet.

13. TownePlace Suites by Marriott San Antonio Airport

Uptown Central

Alejandro

฿4,285 total

includes taxes & fees

31 Oct - 1 Nov

A hotel pool area with two pools, a spa lift, and a wheelchair-accessible sign.

14. Hilton Garden Inn San Antonio Airport South

Uptown Central

Willard

฿3,964 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with a central island, a refrigerator, and a coffee machine.

15. Staybridge Suites San Antonio by IHG

Uptown Central

riccara

฿3,690 total

includes taxes & fees

16 Nov - 17 Nov

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

16. Crowne Plaza San Antonio Airport by IHG

Uptown Central

Zachary

฿3,001 total

includes taxes & fees

27 Oct - 28 Oct

A breakfast bar with various food items and kitchen appliances.

17. Spark by Hilton San Antonio Airport

Uptown Central

Brian

฿2,695 total

includes taxes & fees

22 Nov - 23 Nov

A modern bar area with a long counter, multiple bar stools, and a television screen.

18. Courtyard by Marriott San Antonio Airport

Uptown Central

Rory

฿3,565 total

includes taxes & fees

1 Nov - 2 Nov

A buffet area with a variety of food options, a beverage dispenser, and a fruit bowl.

19. Fairfield Inn & Suites San Antonio Airport/North Star Mall

Uptown Central

david m,

฿3,048 total

includes taxes & fees

5 Nov - 6 Nov

A spacious lobby with a beige sofa, a chandelier, a staircase, and a large window overlooking a parking area.

20. Days Inn by Wyndham San Antonio Airport

Uptown Central

LUCERO

฿2,324 total

includes taxes & fees

27 Oct - 28 Oct

View all properties

Compare popular hotels in Uptown Central

Property	Property class	Guest rating
Drury Plaza Hotel San Antonio Airport	3.0 star property	9.4 Exceptional 2,321 reviews	View
Holiday Inn Express San Antonio-Airport by IHG	2.5 star property	9.4 Exceptional 1,000 reviews	View
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham	2.5 star property	9.0 Wonderful 2,324 reviews	View
Estancia del Norte San Antonio, Tapestry Collection by Hilton	3.5 star property	9.0 Wonderful 1,004 reviews	View
Spark by Hilton San Antonio Airport	2.0 star property	8.8 Excellent 1,852 reviews	View

Where to stay in Uptown Central

Find the best Uptown Central areas for the activities you enjoy most.

A boat tour on a canal with a bridge in the background.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

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A riverside walkway with colorful umbrellas, a stone bridge, and historic buildings.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

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A cityscape with a prominent tower, a large body of water, and a sunset.

Medical Center District

While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

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A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

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A historic stone building with a large wooden door, arched windows, and ornate columns.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

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Top Uptown Central Hotel Reviews

Hampton Inn & Suites San Antonio-Airport

10/10 Excellent

"Clean and safe"

Drury Plaza Hotel San Antonio Riverwalk

10/10 Excellent

"We had a wonderful stay at this hotel! The room was spacious, clean, and very comfortable. The location was fantastic—just a few steps away from the beautiful San Antonio River Walk. One of the best things about this hotel is that it offers complimentary breakfast, which is a great bonus in this area. The staff was incredibly friendly, cheerful, and welcoming. We truly enjoyed our stay and would definitely recommend this hotel!"

Search Hotels in Uptown Central, San Antonio

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Our top choices for Uptown Central hotels

1. Holiday Inn Express San Antonio-Airport by IHG

2. Drury Plaza Hotel San Antonio Airport

3. Embassy Suites by Hilton San Antonio Airport

4. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

5. Estancia del Norte San Antonio, Tapestry Collection by Hilton

6. La Quinta Inn & Suites by Wyndham San Antonio Airport

7. Homewood Suites by Hilton San Antonio Airport

8. Marriott San Antonio Airport

9. Wyndham Garden San Antonio Airport

10. SpringHill Suites by Marriott San Antonio Airport

11. Home2 Suites by Hilton San Antonio Airport, TX

12. Hampton Inn & Suites San Antonio-Airport

13. TownePlace Suites by Marriott San Antonio Airport

14. Hilton Garden Inn San Antonio Airport South

15. Staybridge Suites San Antonio by IHG

16. Crowne Plaza San Antonio Airport by IHG

17. Spark by Hilton San Antonio Airport

18. Courtyard by Marriott San Antonio Airport

19. Fairfield Inn & Suites San Antonio Airport/North Star Mall

20. Days Inn by Wyndham San Antonio Airport

Compare popular hotels in Uptown Central

Where to stay in Uptown Central

Downtown San Antonio

Far West Side

Medical Center District

Northwest Side

Stone Oak

Top Uptown Central Hotel Reviews

Hampton Inn & Suites San Antonio-Airport

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